A potential endemic strain in China: NADC34‑like porcine reproductive and respiratory syndrome virus

Nathues C, Janssen E, Duengelhoef A et al. Cross-sectional study on risk factors for Porcine Reproductive and Respiratory Syndrome virus sow herd instability in German breeding herds. Acta Vet Scand 2018; 60 (1): 1–8 In mit PRRSV (Porcine Reproductive and Respiratory Syndrom Virus) infizierten Schweinebeständen zeigen die Tiere oftmals ernsthafte klinische Symptome. Die Schwere der Symptomatik hängt von der Virulenz der jeweiligen Virusstämme ab. Deshalb ist die Impfung gegen diesen Erreger sinnvoll und wird empfohlen, auch wenn sie nicht immer klinische Fälle verhindert bzw. das Virus vollends eliminiert. Aufgrund dessen rückt die Prävention durch Verbesserung der innerbetrieblichen Abläufe zunehmend in den Fokus. Um solche Maßnahmen erfolgreich etablieren zu können, ist es wichtig, den epidemiologischen Status der Herde und mögliche Risikofaktoren zu kennen. Ziel der Studie war deshalb, die Prävalenz der Infektion in Sauenbetrieben in Norddeutschland zu eruieren und verschiedene Arbeitsabläufe hinsichtlich des Risikos der Erregerverbreitung zu untersuchen.

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Faculty Opinions recommendation of Porcine reproductive and respiratory syndrome virus non-structural protein 1 suppresses tumor necrosis factor-alpha promoter activation by inhibiting NF-κB and Sp1.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5531956.5497054 ◽

2010 ◽

Author(s):

D Scott Schmid ◽

Jennifer Folster

Keyword(s):

Tumor Necrosis Factor ◽

Tumor Necrosis Factor Alpha ◽

Tumor Necrosis ◽

Respiratory Syndrome Virus ◽

Structural Protein ◽

Promoter Activation ◽

Necrosis Factor Alpha ◽

Factor Alpha ◽

Necrosis Factor

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Antiviral effect of aqueous extracts of four kinds of tea on porcine reproductive and respiratory syndrome virus

JOURNAL OF HUNAN AGRICULTURAL UNIVERSITY ◽

10.3724/sp.j.1238.2012.00305 ◽

2013 ◽

Vol 38 (3) ◽

pp. 305-309 ◽

Cited By ~ 1

Author(s):

Hong-rui ZHOU ◽

Qi-wu TANG ◽

Xing-long YU ◽

Run-cheng LI ◽

Wei LUO ◽

...

Keyword(s):

Antiviral Effect ◽

Respiratory Syndrome Virus ◽

Aqueous Extracts

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Nucleic Acid Detection of Severe Acute Respiratory Syndrome Virus 2 (SARS-CoV-2): A Research in the Field of Health Economics

SSRN Electronic Journal ◽

10.2139/ssrn.3558020 ◽

2020 ◽

Author(s):

Yanfen Zeng ◽

Min Dou ◽

Yaqian Mao ◽

Yao Li ◽

Xijun Chen ◽

...

Keyword(s):

Nucleic Acid ◽

Health Economics ◽

Severe Acute Respiratory Syndrome ◽

Respiratory Syndrome Virus ◽

Nucleic Acid Detection

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Molecular detection of porcine reproductive and respiratory syndrome virus, porcine circovirus 2 and hepatitis E virus in oral fluid compared to their detection in faeces and serum

BMC Veterinary Research ◽

10.1186/s12917-020-02378-4 ◽

2020 ◽

Vol 16 (1) ◽

Author(s):

Jan Plut ◽

Urska Jamnikar-Ciglenecki ◽

Marina Stukelj

Keyword(s):

Hepatitis E Virus ◽

Oral Fluid ◽

Molecular Detection ◽

Hepatitis E ◽

Porcine Circovirus ◽

Respiratory Syndrome Virus ◽

Porcine Circovirus 2

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129 Genomic Relationship Between PRRSV Wild-type Infection and PRRSV Vaccination for Antibody Response and Reproductive Performance

Journal of Animal Science ◽

10.1093/jas/skab054.032 ◽

2021 ◽

Vol 99 (Supplement_1) ◽

pp. 18-18

Author(s):

Leticia P Sanglard ◽

Felipe Hickmann ◽

Yijian Huang ◽

Kent A Gray ◽

Daniel Linhares ◽

...

Keyword(s):

Antibody Response ◽

Reproductive Performance ◽

Genetic Correlations ◽

Clinical Signs ◽

Respiratory Syndrome Virus ◽

Wild Type ◽

Large White ◽

Selection For ◽

Indicator Trait ◽

Type Infection

Abstract Immunoglobulin G antibody response, measured as sample-to-positive (S/P) ratio, to Porcine Reproductive and Respiratory Syndrome virus (PRRSV) has been proposed as an indicator trait for improved reproductive performance in PRRSV-infected purebred sows and PRRSV-vaccinated crossbred gilts. In this study, we investigated the genetic correlations (rg) of S/P ratio following a PRRSV outbreak and PRRSV-vaccination with performance in non-exposed and PRRSV-exposed sows. PRRSV outbreak phase was defined based on previously described methodologies after the detection of typical clinical signs of PRRSV infection. 541 Landrace sows had S/P ratio measured at ~54 days after the beginning of the PRRSV outbreak (S/Poutbreak), and 906 Landrace x Large White naïve F1 gilts had S/P ratio measured at ~50 days after vaccination with a commercial modified live PRRSV vaccine (S/PVx). 711 and 428 Landrace sows had reproductive performance recorded before and during the PRRSV outbreak, respectively. 811 vaccinated F1 animals had farrowing performance for up to 3 parities. All animals were genotyped for ~28K SNPs. The estimate of rg of S/Poutbreakwith S/PVx was high (rg±SE = 0.72±0.18). Estimates of rg of S/Poutbreak with reproductive performance in F1 sows were low to moderate, ranging from 0.05±0.23 (number stillborn) to 0.30±0.20 (total number born). Estimates of rg of S/PVxwith reproductive performance in non-infected purebred sows were moderate and favorable with number born alive (0.50±0.23), but low (0 to -0.11±0.23) with litter mortality traits. Estimates of rg of S/PVx were moderate and negative (-0.47±0.18) with the number of mummies in PRRSV-infected purebred sows and low with other traits (-0.29±0.18 for total number born to 0.05±0.18 for number stillborn). These results indicate that selection for antibody response following a PRRSV outbreak collected in purebred sows and to PRRSV vaccination collected in commercial crossbred gilts may increase litter size of non-infected and PRRSV-exposed purebred and commercial crossbred sows.

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PRRSV detection by qPCR in processing fluids and serum samples collected in a positive stable breeding herd following mass vaccination of sows with a modified live vaccine

Porcine Health Management ◽

10.1186/s40813-020-00186-8 ◽

2021 ◽

Vol 7 (1) ◽

Author(s):

A. Lebret ◽

P. Berton ◽

V. Normand ◽

I. Messager ◽

N. Robert ◽

...

Keyword(s):

The United States ◽

Live Vaccine ◽

Mass Vaccination ◽

Respiratory Syndrome Virus ◽

Serum Samples ◽

Blood Samples ◽

Stability Monitoring ◽

Breeding Herd ◽

Modified Live Vaccine ◽

Processing Fluid

AbstractIn the last two decades, in France, Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) stabilization protocols have been implemented using mass vaccination with a modified live vaccine (MLV), herd closure and biosecurity measures. Efficient surveillance for PRRSV is essential for generating evidence of absence of viral replication and transmission in pigs. The use of processing fluid (PF) was first described in 2018 in the United States and was demonstrated to provide a higher herd-level sensitivity compared with blood samples (BS) for PRRSV monitoring. In the meantime, data on vertical transmission of MLV viruses are rare even as it is a major concern. Therefore, veterinarians usually wait for several weeks after a sow mass vaccination before starting a stability monitoring. This clinical study was conducted in a PRRSV-stable commercial 1000-sow breed-to-wean farm. This farm suffered from a PRRS outbreak in January 2018. After implementing a stabilisation protocol, this farm was controlled as stable for more than 9 months before the beginning of the study. PF and BS at weaning were collected in four consecutive batches born after a booster sow mass MLV vaccination. We failed to detect PRRSV by qPCR on PF and BS collected in a positive-stable breeding herd after vaccination with ReproCyc® PRRS EU (Boehringer Ingelheim, Ingelheim, Germany).

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