3D PRINTER’S PARAMETER OPTIMIZATION FOR POTENTIAL PATIENT SPECIFIC IMPLANT FABRICATION

2015 ◽  
Vol 76 (7) ◽  
Author(s):  
Abdul Manaf Abdullah ◽  
Dasmawati Mohamad ◽  
Tuan Noraihan Azila Tuan Rahim ◽  
Hazizan Md Akil ◽  
Zainul Ahmad Rajion
Keyword(s):  
Surface Roughness ◽  
Testing Machine ◽  
Patient Specific ◽  
3D Printer ◽  
Topological Properties ◽  
Layer Height ◽  
Universal Testing ◽  
Potential Patient ◽  
Relationship Of ◽  
The Relationship

This study attempted to investigate the effect of printing orientation and layer height on mechanical and topological properties of printed ABS specimens. 2 printing orientations (xy and yz) with 3 different layer heights (0.1, 0.2 and 0.3mm) were chosen and specimens were printed utilizing a 3D printer. Tensile, morphological and topological properties were evaluated utilizing Universal Testing Machine (Shimadzu AGX-2plus), FESEM and surface profilometer respectively. Statistical analysis of two-way Anova was carried out to investigate the relationship of layer height and printing orientation on the tensile strength and surface roughness of the specimens

Strength of Ductile Adhesive Butt Joint Bonded with Dissimilar Adherents: Effect of Surface Roughness

2014 ◽  
Vol 554 ◽  
pp. 366-370 ◽  
Author(s):  
Nurul Atikah ◽  
Mohd Afendi ◽  
Siti Hirmaliza ◽  
Mohd Shukry Abdul Majid ◽  
Nurul Amira ◽  
...  
Keyword(s):  
Surface Roughness ◽  
Static Loading ◽  
Testing Machine ◽  
Butt Joint ◽  
Butt Joints ◽  
Universal Testing ◽  
Different Types ◽  
Relationship Of ◽  
The Relationship ◽  
Effect Of Surface

The purpose of this project is to study the influence of the macroscopic state of surface roughness of the dissimilar adherent on the strength of adhesive joint. In this project, several types of sandpaper were used to produce different surface roughness of stainless steel and aluminium alloy adherents. All bonding surfaces were polished with different types of sandpaper. Butt joints of dissimilar adherent specimen were produced using a ductile adhesive (i.e. Araldite®Standard) with same bond thickness. The specimens were tested under static loading condition using universal testing machine (UTM) to investigate the relationship of the surface roughness and bond strength.

Experimental Research on Relationship of Load and Displacement of Universal Testing Machine

2011 ◽  
Vol 250-253 ◽  
pp. 1582-1587 ◽  
Author(s):  
Jiang Xu ◽  
Li Feng Lu ◽  
Hong Wei Yang ◽  
Jin Neng Wang ◽  
Yuan Zhang
Keyword(s):  
Cyclic Loading ◽  
Testing Machine ◽  
Pressure Head ◽  
Material Testing ◽  
Pressure Plate ◽  
Universal Testing Machine ◽  
Universal Testing ◽  
Material Testing Machine ◽  
Relationship Of ◽  
The Relationship

The related components of material testing machine (e.g., pressure plate, pressure head, compression bar, etc.) produce distortion in the experiment. It is obviously irrational to use the stroke to replace the specimen displacement, which can’t be measured directly by the extensometer in the destructive test. Therefore, the evolution of specimen displacement, machine displacement and stroke of 45 steel, duralumin alloy and sandstone was analyzed under uniaxial monotonic loading and uniaxial cyclic loading. The results show that the deformation of the related components of universal testing machine, which increases/decreases along with the increase/ decrease of load, can’t be ignored. And there is a good one-to-one correspondence between the machine displacement and the load. It also has nothing to do with the types of specimen materials and the experiments. The relationship of machine displacement and the load can be used to determine the specimen displacement indirectly.

Study on Characteristics of Ultrasonic Velocity for the Concrete under Stress

2013 ◽  
Vol 438-439 ◽  
pp. 220-223 ◽  
Author(s):  
Ling Zhang ◽  
Chun Ling Yan
Keyword(s):  
Ultimate Strength ◽  
Ultrasonic Velocity ◽  
Ultrasound Examination ◽  
Testing Machine ◽  
Strength Level ◽  
Growth Trend ◽  
Universal Testing Machine ◽  
Universal Testing ◽  
Three Stages ◽  
The Relationship

Cube concrete (150×150×150mm) of five ages (7, 14, 21, 28 and 35 days) under different stress conducted the ultrasound examination by non-metallic detector and universal testing machine. The results show that the relationship curve of the stress and the ultrasonic velocity can be divided into three stages, the smooth straight stage, the linear deceleration stage and the attenuation destruction stage from the load beginning to the ultimate strength for the same age. There is a growing trend about the ultrasonic velocity with the increase of the age to concrete samples of C10 and C20 in the same loading; however, the overall growth trend of the velocity is not obvious to concrete samples of C30, C35, C40 and C45. It also shows that the relationship curve of strength level and the velocity can be divided into two distinct stages, the sharply increasing stage (C10-C30) and the fluctuating stage (C30-C45). Simultaneously, the paper further illustrates and explains the reasons to appear these stages and the phenomena.

Study on Surface Roughness Based on Dynamic Minimum Thickness of Cut

2011 ◽  
Vol 88-89 ◽  
pp. 34-37
Author(s):  
Kuai Ji Cai
Keyword(s):  
Surface Roughness ◽  
Friction Coefficient ◽  
Atomic Force Microscope ◽  
Surface Quality ◽  
Experimental Verification ◽  
Cutting Parameters ◽  
Minimum Thickness ◽  
Atomic Force ◽  
Relationship Of ◽  
The Relationship

The relationship of the friction coefficient and the MTC were discussed, and the MTC and its effects on surface roughness were a theoretical analysised and experimental verification by AFM (atomic force microscope). The results show that the theoretical MTC tends to be minimal value then before the adhering effect to reach remarkable. Appropriate adjustments cutting parameters, the cutting process can always micro-cutting phase to reach the steady-thin chip, and no plowing phenomenon. So the surface residues highly were reduced and higher surface quality was achieved.

Effect Analysis of Temperature on the Rubber Material Stress-Strain Relationship

2014 ◽  
Vol 977 ◽  
pp. 116-119 ◽  
Author(s):  
Yu Liang Yang ◽  
Liang Qiao ◽  
Cong Wang ◽  
Fei Lu ◽  
Xiao Hui Kang
Keyword(s):  
Environmental Temperature ◽  
Testing Machine ◽  
Test Results ◽  
Stress Strain ◽  
Rubber Material ◽  
Effect Analysis ◽  
Universal Testing ◽  
Different Temperatures ◽  
Strain Relationship ◽  
Relationship Of

For the effect of environmental temperature on the rubber material stress-strain relationships, rubber tensile specimens, compression specimens and shear specimens were made. Through the electronic universal testing machine Instron 5500R, the stress-strain curves of three kinds of specimens at different temperatures were obtained. The test results showed that the stress-strain relationship of rubber material was typically nonlinear. As the temperature increased, the elastic modulus of rubber material decreased.

Research on Surface Roughness of Die Steel in Micro-Etching

2013 ◽  
Vol 785-786 ◽  
pp. 896-900
Author(s):  
Hong Guang Huang ◽  
Guan Wang ◽  
Zhong Ning Guo ◽  
Qing Song ◽  
Yu Deng
Keyword(s):  
Surface Roughness ◽  
Laser Scanning ◽  
Etching Time ◽  
Micro Channel ◽  
Die Steel ◽  
Etching Method ◽  
Etching Factor ◽  
Relationship Of ◽  
The Relationship

In this study, the 300 µm width micro-channel was manufactured by spray etching method. The surface roughness was analyzed by Laser scanning con-focal microscope. The relationship of the surface roughness and etching factor such as spray etching pressure, mask gap and time had been studied. The results show that the surface roughness increases initially, and then reduces with the size of mask gap. While the roughness increases as the spraying pressure increases. The etching time plays slightly effect on roughness for it has no impact on the etch uniformity as mask gap and spray pressure do.

scholarly journals Residual Strength of Carabiners Used by Tree Climbers

2009 ◽  
Vol 35 (2) ◽  
pp. 75-79
Author(s):  
Brian Kane ◽  
H. Dennis Ryan
Keyword(s):  
New York ◽  
Surface Roughness ◽  
Residual Strength ◽  
Testing Machine ◽  
Maximum Load ◽  
Universal Testing Machine ◽  
Universal Testing ◽  
Serious Injury ◽  
Long Term Studies

Tree climbers increasingly use carabiners and apply them in situations for which they are not designed. Because failure of carabiners can result in serious injury or death, the following study tested how well carabiners endure the stress to which climbers subject them. This study distributed carabiners of four types (all manufactured by Petzl) to climbers in Massachusetts and New York, USA, and collected them a year later. Then, carabiners were broken in a universal testing machine and measured the maximum load, as well as surface roughness. No carabiners broke below their rated strength; and used carabiners were, with one exception, as strong as new carabiners. Surface roughness was a weak, but significant, predictor of strength. Findings are discussed in light of climber safety and the importance of conducting long-term studies.

The relationship of vancomycin 24-hour AUC and trough concentration

2021 ◽  
Author(s):  
David E Nix ◽  
Lisa E Davis ◽  
Kathryn R Matthias
Keyword(s):  
Trough Concentration ◽  
Elimination Rate ◽  
Compartment Model ◽  
Patient Specific ◽  
Pharmacokinetic Parameters ◽  
Time Curve ◽  
Dosing Interval ◽  
Trough Concentrations ◽  
Relationship Of ◽  
The Relationship

Abstract Disclaimer In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time. Purpose Prior to the 2020 release of a joint consensus guideline on monitoring of vancomycin therapy for serious methicillin-resistant Staphylococcus aureus (MRSA) infections, clinicians had escalated vancomycin doses for 2 decades while targeting trough concentrations of 15 to 20 µg/mL, leading to an increased frequency of nephrotoxicity. For MRSA infections, the 2020 guideline recommends adjusting doses to achieve a 24-hour area under the concentration-time curve (AUC) of 400 to 600 µg · h/mL; however, monitoring of trough concentrations has been entrenched for 3 decades. Calculating dose regimens based on AUC will require obtaining an increased number of vancomycin serum concentrations and, possibly, advanced software. The aim of this investigation was to determine the relationship between AUC and trough concentration and the influence of dosing regimen on goal achievement. Methods The relationship between trough concentration and AUC was explored through derivation of an equation based on a 1-compartment model and simulations. Results 24-hour AUC is related to dosing interval divided by half-life in a nonlinear fashion. The target trough concentration can be individualized to achieve a desired AUC range, and limiting use of large doses (>15-20 mg/kg) can protect against excessive 24-hour AUC with trough-only monitoring. Conclusion After initially determining pharmacokinetic parameters, subsequent monitoring of AUC can be accomplished using trough concentrations only. Trough concentration may be used as a surrogate for AUC, although the acceptable target trough concentration will vary depending on dosing interval and elimination rate constant. This work included development of an AUC-trough equation to establish a patient-specific target for steady-state trough concentration.

scholarly journals Pharmacokinetic/Toxicodynamic Analysis of Colistin-Associated Acute Kidney Injury in Critically Ill Patients

2017 ◽  
Vol 61 (11) ◽  
Author(s):  
Alan Forrest ◽  
Samira M. Garonzik ◽  
Visanu Thamlikitkul ◽  
Evangelos J. Giamarellos-Bourboulis ◽  
David L. Paterson ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Steady State ◽  
Renal Replacement Therapy ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Kidney Injury ◽  
Patient Factors ◽  
Potential Patient ◽  
Relationship Of ◽  
The Relationship

ABSTRACT Acute kidney injury (AKI) occurs in a substantial proportion of critically ill patients receiving intravenous colistin. In the pharmacokinetic/toxicodynamic analysis reported here, the relationship of the occurrence of AKI to exposure to colistin and a number of potential patient factors was explored in 153 critically ill patients, none of whom were receiving renal replacement therapy. Tree-based modeling revealed that the rates of AKI were substantially higher when the average steady-state plasma colistin concentration was greater than ∼2 mg/liter.

Study on Constitutive Relationship of Fe-36Ni Invar Alloy

2011 ◽  
Vol 291-294 ◽  
pp. 1131-1135
Author(s):  
Guo He Li ◽  
Yu Jun Cai ◽  
Hou Jun Qi
Keyword(s):  
Strain Rate ◽  
Split Hopkinson Pressure Bar ◽  
Testing Machine ◽  
Constitutive Relationship ◽  
Invar Alloy ◽  
Hopkinson Pressure Bar ◽  
Universal Testing ◽  
Split Hopkinson ◽  
Pressure Bar ◽  
Relationship Of

By electronic universal testing machine and Split Hopkinson Pressure Bar, the mechanical properties data of Fe-36Ni invar alloy are gained at a range of temperature from 20°C to 800°C and strain rate from 10-3 /s to 104/s. An improved Johnson-Cook model is presented to describe the mechanical behavior of Fe-36Ni invar alloy at high temperature and high strain rate, and verified by experimental results.

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