Blood Lipid and Percent Body Fat Levels in Down Syndrome versus Non-DS Persons with Mental Retardation

1992 ◽  
Vol 9 (2) ◽  
pp. 123-129 ◽  
Author(s):  
James H. Rimmer ◽  
Dave Braddock ◽  
Glenn Fujiura
Keyword(s):  
Down Syndrome ◽  
Mental Retardation ◽  
Body Fat ◽  
Ldl Cholesterol ◽  
Hdl Cholesterol ◽  
Blood Lipid ◽  
Percent Body Fat ◽  
Regression Approach ◽  
And Storage ◽  
Physiological And Biochemical

Little data exist on the comparison of blood lipids and percent body fat between Down Syndrome and non-DS adults with mental retardation (MR). The following study was undertaken to determine if there were physiological and biochemical differences between these two groups. Subjects included 294 non-DS adults with MR (162 males and 132 females) and 31 adults with Down Syndrome (21 males and 10 females). Level of mental retardation was similar for both groups (males/females, Down vs. non-DS). A two-factor ANOVA with a regression approach was used to analyze the data. Results of the study found that there were no significant differences between the Down Syndrome and non-DS subjects on total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, or percent body fat. The present study suggests that the composition of lipoproteins and storage of body fat are similar in Down Syndrome and non-DS adults with mental retardation, and that the risk for developing coronary heart disease appears to be the same for both groups.

Congruence of Three Risk Indices for Obesity in a Population of Adults with Mental Retardation

1994 ◽  
Vol 11 (4) ◽  
pp. 396-403 ◽  
Author(s):  
James H. Rimmer ◽  
David Braddock ◽  
Glenn Fujiura
Keyword(s):  
At Risk ◽  
Mental Retardation ◽  
Body Fat ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Blood Lipid ◽  
Weight Percent ◽  
Excess Weight ◽  
Lipoprotein Cholesterol ◽  
Percent Body Fat

A body mass index (BMI) greater than 27 has been cited as a risk factor for heart disease and diabetes mellitus resulting from excess weight. The purpose of this study was to determine the association between BMI (>27) and two other obesity indices–height-weight and percent body fat–as well as to investigate the relationship between BMI and three blood lipid parameters–total cholesterol, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) in 329 adults with mental retardation (MR). Males were significantly taller and heavier than females, but females had a significantly higher BMI. Kendall’s Tau-C revealed a significant association between BMI and each of the following: height-weight, percent body fat, LDL-C, and HDL-C. However, there were a significant number of false negatives and false positives on each of the criteria. The congruence between at-risk BMI and two other obesity parameters (height-weight and percent body fat) in a population of adults with MR is not strong. Professionals should employ the BMI along with skinfold measures to assess a person’s at-risk status for excess weight.

Physical Fitness of Trained Runners with and without Mild Mental Retardation

1999 ◽  
Vol 16 (2) ◽  
pp. 126-137 ◽  
Author(s):  
Georgia C. Frey ◽  
Jeffrey A. McCubbin ◽  
Steve Hannigan-Downs ◽  
Susan L Kasser ◽  
Steven O. Skaggs
Keyword(s):  
Mental Retardation ◽  
Physical Fitness ◽  
Body Fat ◽  
Knee Flexion ◽  
Peak Torque ◽  
Percent Body Fat ◽  
Mild Mental Retardation ◽  
Lower Back ◽  
Hamstring Flexibility ◽  
Trained Runners

The purpose of this study was to compare physical fitness levels of trained runners with mild mental retardation (MMR) (7 males and 2 females, age = 28.7 ± 7.4 years, weight = 67.0 ± 11.7 kg) and those without (7 males and 2 females, age = 29.1 ± 7.5, weight = 68.7 ± 8.8 kg). Paired t tests revealed no differences between runners with and without MMR on measures of V̇O2peak (56.3 ± 9.1 vs. 57.7 ± 4.1 ml · kg-1 · min-1), percent body fat (16.6 ± 8.4 vs. 16.6 ± 3.1), and lower back/hamstring flexibility (33.1 ± 10.9 vs. 28.6 ± 10.1 cm). Knee flexion (KF) and extension (KE) strength were significantly greater in runners without MMR compared to those with MMR (KF peak torque = 65.7 ±7.9 vs. 48.7 ± 15.7 ft/lb; KE peak torque = 138.5 ± 17.7 vs. 104.4 ± 29.9 ft/lb). It was concluded that trained runners with MMR can achieve high levels of physical fitness comparable to individuals without MMR.

scholarly journals AMPK subunits harbor largely non-overlapping genetic determinants for body fat mass, glucose- and cholesterol metabolism

2019 ◽  
Author(s):  
Elko Randrianarisoa ◽  
Angela Lehn-Stefan ◽  
Johannes Krier ◽  
Anja Böhm ◽  
Martin Heni ◽  
...  
Keyword(s):  
Insulin Secretion ◽  
Blood Glucose ◽  
Insulin Sensitivity ◽  
Body Fat ◽  
Ldl Cholesterol ◽  
Cholesterol Metabolism ◽  
Hdl Cholesterol ◽  
Oral Glucose ◽  
Genetic Determinants ◽  
The Impact

Abstract Context AMP-activated protein kinase (AMPK) is a heterotrimeric enzyme and central regulator of cellular energy metabolism. The impact of single nucleotide polymorphisms (SNPs) in all seven subunit genes on adiposity, glucose- and lipid metabolism has not been systematically studied yet. Objective To analyze the associations of common SNPs in all AMPK genes, and of different scores thereof, with adiposity, insulin sensitivity, insulin secretion, blood glucose, total-, LDL- and HDL-cholesterol and triglycerides. Study Design and Methods A cohort of 2789 non-diabetic subjects from the Tübingen Family study of type-2 diabetes, metabolically characterized by oral glucose tolerance test and genotyped by genome-wide SNP array was analyzed. Results We identified largely non-overlapping SNP sets across four AMPK genes (PRKAA1, PRKAA2, PRKAG2, PRKAG3) associated with adiposity, insulin sensitivity, insulin secretion, blood glucose, total-/LDL-cholesterol or HDL-cholesterol, respectively. A genetic score of body-fat-increasing alleles revealed per-allele effect sizes on BMI of +0.22 kg/m² (p=2.3·10-7), insulin sensitivity of -0.12·1019 L²/mol² (p=9.9·10-6) and 2-h blood glucose of +0.02 mmol/L (p=0.0048). Similar effects on blood glucose were observed with scores of insulin-sensitivity-reducing, insulin-secretion-reducing and glucose-raising alleles, respectively. A genetic cholesterol score increased total- and LDL-cholesterol by 1.17 mg/dL per allele (p=0.0002 and p=3.2·10-5, respectively), and a genetic HDL score decreased HDL-cholesterol by 0.32 mg/dL per allele (p=9.1·10-6). Conclusions We describe largely non-overlapping genetic determinants in AMPK genes for diabetes-/atherosclerosis-related traits which reflect the metabolic pathways controlled by the enzyme. Formation of trait-specific genetic scores revealed additivity of allele effects, with body-fat-raising alleles reaching a marked effect size.

scholarly journals Effect of feeding goat meat containing low cholesterol and rich omega-6 fatty acid on blood lipid status of white rat (Rattus norvegicus)

2021 ◽  
pp. 1966-1970
Author(s):  
Widiyanto Widiyanto ◽  
Mulyono Mulyono ◽  
Sutrisno Sutrisno ◽  
Eko Pangestu ◽  
Marry Christiyanto ◽  
...  
Keyword(s):  
Total Cholesterol ◽  
Ldl Cholesterol ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Blood Lipid ◽  
Goat Meat ◽  
Cholesterol Levels ◽  
White Rats ◽  
Omega 6 ◽  
Low Cholesterol

Background and Aim: Healthy goat meat is an essential aspect in increasing consumer acceptance for this livestock product. The research aimed to examine the effect of goat meat containing low cholesterol and rich omega-6 fatty acid on the performance and blood lipid status of white rats (Rattus norvegicus). Materials and Methods: Thirty 2-month-old male white rats (R. norvegicus) weighing 195-230 g were randomly divided into three groups, with each group consisting of 10 rats. Group I was treated with a control feed (T0; BR I concentrate). Group II (T1) was treated with a mixed feed containing 50% control feed and 50% goat meat. Group III (T2) was treated with a mixed feed comprising 50% control feed and 50% goat meat with low cholesterol and rich omega-6 fatty acids. Each treatment was given ad libitum for 30 days. The variables measured were dry matter and organic matter consumption, daily body weight gain, feed conversion, triglyceride levels, total cholesterol, high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol, and atherogenic index (AI). The data were analyzed statistically using analysis of variance in a completely randomized design. Results: The total, HDL, and LDL cholesterol levels at T0, T1, and T2 were as follows: 99.97, 35.97, and 50.43 mg/dL (total cholesterol); 108.35, 33.92, and 58.17 mg/dL (HDL cholesterol); and 101.43, 38.09, and 48.65 mg/dL (LDL cholesterol). The highest HDL and the lowest LDL cholesterol levels (p<0.05) were observed in the T2 treatment group, which had the lowest AI (1.69 vs. 1.77 and 2.19). Conclusion: The consumption of goat with low cholesterol and rich omega-6 fatty acids reduces the total cholesterol and LDL cholesterol, raises the HDL cholesterol levels, and decreases the AI.

scholarly journals Associations between choline intake, body composition, lipid profile, and liver status in healthy adults

2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Monika Młodzik-Czyżewska ◽  
Anna Malinowska ◽  
Agata Chmurzyńska
Keyword(s):  
Body Composition ◽  
Body Weight ◽  
Body Fat ◽  
Ldl Cholesterol ◽  
Liver Steatosis ◽  
Hdl Cholesterol ◽  
Body Fat Percentage ◽  
Fat Percentage ◽  
The Mean ◽  
Choline Intake

AbstractCholine is an essential nutrient involved in several processes, including the export of lipids from the liver. Recent studies have underlined that low choline intake may be linked to greater body weight and liver dysfunction. The aim of this study was thus to determine whether choline intake is associated with body weight, body mass index (BMI), body composition, lipid profile, or liver steatosis indices.407 healthy subjects aged 20–40 were enrolled in Poznań, Poland from 2016 to 2018. Food intake was assessed using three-day food records. Choline intake was analyzed using the USDA Database for the Choline Content of Common Foods, which summarizes the levels of choline found in a range of food items. Weight to 0.1 kg and height to 0.01 m were measured using an electronic scale and a stadiometer, respectively. BMI was calculated as body weight in kilograms divided by height in meters squared. Fat mass and lean body mass were determined using whole-body air-displacement plethysmography. Waist and hip circumferences were measured to 0.5 cm using nonelastic tape. Total cholesterol, LDL cholesterol, HDL cholesterol, and triglyceride levels in serum were determined using a biochemical analyzer. The following biomarkers of liver steatosis were calculated: NAFLD liver fat score (NAFLD-LFS), fatty liver index (FLI), and hepatic steatosis index (HSI). To analyze associations between choline intake and these parameters, we used multiple regression with adjustments for age, sex, and energy intake.The mean BMI was 25.9 ± 5.28 kg/m2, the mean body weight was 78.39 ± 18.03 kg, the mean body fat percentage was 29.1 ± 10.79%, and the mean choline intake was 447.93 ± 235 mg/day. Choline intake was negatively associated with body weight, body fat percentage, waist circumference, and FLI index (p < 0.05 for all associations) and positively associated with HDL cholesterol (p < 0.05). There were no associations between choline intake and BMI, hip circumference, total cholesterol, LDL cholesterol, and the following fatty liver indexes: HSI and NAFLD-LFS.Our study suggests that higher choline intake is associated with favorable body composition and may have a protective role on liver status. However, additional studies are needed to understand the effect of choline on these parameters.The authors declare that they have no conflict of interests.This work was supported by the Polish National Science Centre (grants 2014/15/B/NZ9/02134 and 2016/21/N/NZ9/01195).

Effects of Reinforcement Based Exercise on Fitness and Work Productivity in Adults with Mental Retardation

1992 ◽  
Vol 9 (2) ◽  
pp. 148-178 ◽  
Author(s):  
Ronald Croce ◽  
Michael Horvat
Keyword(s):  
Body Weight ◽  
Mental Retardation ◽  
Body Fat ◽  
Treatment Effectiveness ◽  
Fat Body ◽  
Work Productivity ◽  
Exercise Program ◽  
Weight Percent ◽  
Cardiovascular Fitness ◽  
Percent Body Fat

The present study evaluated the effects of a reinforcement based aerobic and resistance exercise program on three obese men with mental retardation and below average fitness levels. A multiple-baseline-across-subjects design was employed to evaluate treatment effectiveness and retention of treatment effects on five dependent measures: body weight, percent body fat (body composition), oxygen consumption (predicted max V̇O2 in ml/kg/min), composite isometric strength (in kg of force), and work productivity (pieces of work completed). Subjects improved during treatment from their baseline scores on cardiovascular fitness, strength, and work productivity measurements (p<.05); however, retention of gains made during treatment were inconsistent and the data that indicated subjects’ scores were regressing back toward baseline measurements. There were no significant differences for body weight and percent body fat measurements for treatment and retention phases (p>.05). Results indicated that adults with mental retardation respond to a progressive exercise program in much the same manner as their nonretarded peers and that such an exercise program can facilitate job performance.

scholarly journals Effects of Aerobic Dancing on Homocysteine and Blood Lipid Status

2010 ◽  
Vol 16 (1) ◽  
pp. 79-85
Author(s):  
Shin Lin TSAI ◽  
Pu Hsi TSAI ◽  
Chou Chun HUANG ◽  
Tswen Kei TANG ◽  
Wein Shiang TSAI
Keyword(s):  
Aerobic Exercise ◽  
Total Cholesterol ◽  
Ldl Cholesterol ◽  
Hdl Cholesterol ◽  
Blood Lipid ◽  
Female Students ◽  
Moderate Intensity ◽  
Lipid Status ◽  
Intensity Of Exercise ◽  
Status Level

LANGUAGE NOTE | Document text in Chinese; abstract also in English. Aerobic exercise can improve blood lipid status, homocysteine help for cardiovascular diseases. The purpose of this study was to investigate the effect of aerobic exercise on homocysteine and blood lipid status level. Eleven female students serve as the experiment subjects. They will do two hours of aerobic dancing without rest. They can drink water whenever they want. The intensity of exercise is between 55%~70% HRmax. Blood of the subjects will be drawn from the vein at pre-exercise, after exercise. Then the concentration of homocysteine, total cholesterol, triacylglycerol, LDL-cholesterol, and HDL-cholesterol will be measured. The results showed that: After Aerobic dancing, homocysteine and triacylglycerol were significant higher (p<.05) than per exercise. LDL-cholesterol in the post Aerobic dancing was significant lower (p<.05) than pre exercise. There were no significant differences in HDL-cholesterol and total cholesterol between pre-exercise and post­exercise. The results indicated that moderate-intensity aerobic dancing can improve blood lipid status. 有氧運動可以預防心血管疾病，而同半胱胺酸都與心血管疾病有關，因此本研究的目的在探討單次有氧舞蹈前後對同半胱胺酸及血脂狀態的影響。本研究以十一位女性大學生為受試者，從事連續二小時的有氧舞蹈，運動期間並不休息，可自由飲水，並將運動強度控制在55%~70%最大心跳率。在運動前後測量血漿中同半胱胺酸、總膽固醇、三酸甘油酯、低密度脂蛋白膽固醇及高密度脂蛋白膽固醇。結果發現：有氧舞蹈後同半胱胺酸及三酸甘油脂顯著增加，低密度脂蛋白膽固醇運動後顯著降低，其他則沒有改變。顯示中等強度的有氧舞蹈可以改善血脂狀況。

The latest research on coconut oil and human health

2021 ◽  
Vol 32 (10) ◽  
pp. 28-29
Author(s):  
Rebecca Guenard ◽  
Keyword(s):  
Clinical Trials ◽  
Total Cholesterol ◽  
Ldl Cholesterol ◽  
Meta Analysis ◽  
Coconut Oil ◽  
Hdl Cholesterol ◽  
Blood Lipid ◽  
Oil Consumption ◽  
Controlled Clinical Trials ◽  
Human Adults

A meta-analysis of clinical trials comparing the effects of coconut oil consumption with other fats focused only on controlled clinical trials performed on human adults with a duration exceeding two weeks (long enough to let blood lipid concentrations stabilize).coconut oil consumption significantly increased total cholesterol, LDL-cholesterol, and HDL-cholesterol concentrations compared with non-tropical vegetable oils and significantly increased total cholesterol and LDL-cholesterol concentrations compared with palm oil.

Sign in / Sign up

Export Citation Format

Share Document