The Association of a High Drive for Thinness With Energy Deficiency and Severe Menstrual Disturbances: Confirmation in a Large Population of Exercising Women

2011 ◽  
Vol 21 (4) ◽  
pp. 280-290 ◽  
Author(s):  
Jenna C. Gibbs ◽  
Nancy I. Williams ◽  
Jennifer L. Scheid ◽  
Rebecca J. Toombs ◽  
Mary Jane De Souza

A high drive-for-thinness (DT) score obtained from the Eating Disorder Inventory-2 is associated with surrogate markers of energy deficiency in exercising women. The purposes of this study were to confirm the association between DT and energy deficiency in a larger population of exercising women that was previously published and to compare the distribution of menstrual status in exercising women when categorized as high vs. normal DT. A high DT was defined as a score ≥7, corresponding to the 75th percentile for college-age women. Exercising women age 22.9 ± 4.3 yr with a BMI of 21.2±2.2 kg/m2 were retrospectively grouped as high DT (n = 27) or normal DT (n = 90) to compare psychometric, energetic, and reproductive characteristics. Chi-square analyses were performed to compare the distribution of menstrual disturbances between groups. Measures of resting energy expenditure (REE) (4,949 ± 494 kJ/day vs. 5,406 ± 560 kJ/day, p < .001) and adjusted REE (123 ± 16 kJ/LBM vs. 130 ± 9 kJ/LBM, p = .027) were suppressed in exercising women with high DT vs. normal DT, respectively. Ratio of measured REE to predicted REE (pREE) in the high-DT group was 0.85 ± 0.10, meeting the authors’ operational definition for an energy deficiency (REE:pREE <0.90). A greater prevalence of severe menstrual disturbances such as amenorrhea and oligomenorrhea was observed in the high-DT group (χ2 = 9.3, p = .003) than in the normal-DT group. The current study confirms the association between a high DT score and energy deficiency in exercising women and demonstrates a greater prevalence of severe menstrual disturbances in exercising women with high DT.

2010 ◽  
Vol 42 ◽  
pp. 109-110
Author(s):  
Jenna C. Gibbs ◽  
Nancy I. Williams ◽  
Jennifer L. Scheid ◽  
Rebecca J. Toombs ◽  
Mary Jane De Souza

Appetite ◽  
2007 ◽  
Vol 48 (3) ◽  
pp. 359-367 ◽  
Author(s):  
Mary Jane De Souza ◽  
Rayisa Hontscharuk ◽  
Marion Olmsted ◽  
Gretchen Kerr ◽  
Nancy I. Williams

2020 ◽  
Vol 45 (7) ◽  
pp. 707-714 ◽  
Author(s):  
Kristen J. Koltun ◽  
Nancy I. Williams ◽  
Jennifer L. Scheid ◽  
Mary Jane De Souza

The mechanism underlying oligo/amenorrhea in exercising women is often presumed as hypothalamic inhibition secondary to energy deficiency; however, hyperandrogenism may provide an alternative mechanism in some exercising women. Our purpose was to compare reproductive, metabolic, and androgen profiles of exercising women with eumenorrheic, ovulatory menstrual cycles (n = 91), oligo/amenorrhea without evidence of hyperandrogenism (Oligo/Amen; n = 83), and oligo/amenorrhea with evidence of hyperandrogenism (Oligo/Amen-HA; n = 17), and determine the prevalence of oligo/amenorrhea with evidence of hyperandrogenism in exercising women. Self-reported menstrual history and quantification of daily estrogen and progesterone urinary metabolites determined reproductive status. Resting energy expenditure, body composition, and metabolic hormone concentrations determined metabolic status. Serum androgens and calculated free androgen index (FAI) determined androgen status. Groups were similar in age (22.4 ± 0.3 years), height (165.1 ± 0.5 cm), resting energy expenditure (1198.4 ± 12.0 kcal/day), and total triiodothyronine (85.0 ± 1.5 ng/dL) concentration. Oligo/Amen-HA had greater weight (60.0 ± 1.6, 56.1 ± 0.7 kg), body mass index (22.3 ± 0.4, 20.6 ± 0.2 kg/m2), percentage body fat (27.3% ± 1.4%, 24.4% ± 0.6%), fat mass (16.2 ± 1.0, 13.8 ± 0.4 kg), insulin (5.8 ± 0.7, 4.2 ± 0.3 μIU/mL), leptin (12.2 ± 2.3, 6.6 ± 0.7 ng/mL), FAI (6.1 ± 0.3, 1.7 ± 0.1), and luteinizing hormone/follicle-stimulating hormone (1.9 ± 0.3, 1.3 ± 0.2) compared with Oligo/Amen, respectively. In our sample, 17% of those with oligo/amenorrhea had concurrent hyperandrogenism. This study supports that oligo/amenorrhea in some exercising women is related to hyperandrogenism. Novelty Caution must be utilized when discriminating hypothalamic oligo/amenorrhea from hyperandrogenic oligo/amenorrhea. In our sample, 17% of those with presumed hypothalamic oligo/amenorrhea had concurrent hyperandrogenism. Exercise and/or mild energy deficiency may be protective against developing severe hyperandrogenic symptoms.


2019 ◽  
Vol 104 (8) ◽  
pp. 3131-3145 ◽  
Author(s):  
Emily A Southmayd ◽  
Nancy I Williams ◽  
Rebecca J Mallinson ◽  
Mary Jane De Souza

Abstract Context In exercising women, energy deficiency can disrupt the balance of bone formation and resorption, resulting in bone loss and an altered rate of bone turnover, which may influence future bone mineral density and fracture risk. Objective To assess the effects of energy status and estrogen status on bone turnover. Design Cross-sectional. Setting The Women’s Health and Exercise Laboratory at Pennsylvania State University. Participants Exercising women (n = 109) operationally defined as energy deficient or replete based on total triiodothyronine concentration and as estrogen deficient or replete based on menstrual cycle history and reproductive hormone metabolites. Main Outcome Measures Bone formation index [procollagen type I N-terminal propeptide (P1NP) concentration corrected for average P1NP concentration in healthy reference group, i.e., [P1NP]i/median [P1NP]ref], bone resorption index [serum C-terminal telopeptide (sCTx) concentration corrected for average sCTx concentration in healthy reference group, i.e., [sCTx]i/median [sCTx]ref], bone balance (ratio of bone formation index to bone resorption index to indicate which process predominates), and bone turnover rate (collective magnitude of bone formation index and bone resorption index to indicate overall amount of bone turnover). Results The combination of energy and estrogen deficiency resulted in less bone formation and a lower rate of bone turnover compared with women who were estrogen deficient but energy replete. Regardless of estrogen status, energy deficiency was associated with decreased bone resorption as well. No main effects of estrogen status were observed. Conclusions The results highlight the critical role that adequate energy plays in the regulation of bone turnover, especially bone formation, in exercising women with menstrual disturbances.


Author(s):  
Sarfaraz Masood ◽  
Khwaja Wisal ◽  
Om Pal ◽  
Chanchal Kumar

Parkinson’s disease (PD) is a highly common neurological disease affecting a large population worldwide. Several studies revealed that the degradation of voice is one of its initial symptoms, which is also known as dysarthria. In this work, we attempt to explore and harness the correlation between various features in the voice samples observed in PD subjects. To do so, a novel two-level ensemble-based feature selection method has been proposed, whose results were combined with an MLP based classifier using K-fold cross-validation as the re-sampling strategy. Three separate benchmark datasets of voice samples were used for the experimentation work. Results strongly suggest that the proposed feature selection framework helps in identifying an optimal set of features which further helps in highly accurate identification of PD patients using a Multi-Layer Perceptron from their voice samples. The proposed model achieves an overall accuracy of 98.3%, 95.1% and 100% on the three selected datasets respectively. These results are significantly better than those achieved by a non-feature selection based option, and even the recently proposed chi-square based feature selection option.


2020 ◽  
Vol 8 (T2) ◽  
pp. 115-118
Author(s):  
Nofita Setiorini Futri Purwanto ◽  
Masni Masni ◽  
M. Nadjib Bustan

BACKGROUND: Chronic energy deficiency (CED) is a condition of malnutrition of pregnant women which have an advanced impact in the form of health problems and complications in the mother and baby. For this reason, it is necessary to work toward prevention by knowing the socioeconomic influence on CED. AIM: The aim of the study was to determine the effect of socioeconomics on the incidence of CED in pregnant women. METHODS: This research is observational analytic with case–control research design. A sample of 99 pregnant women was taken from the working area of the Sudiang Raya Health Center. This sample consisted of 33 case groups of mothers with CED and 66 control groups of pregnant women who did not suffer from CED who had met the inclusion and exclusion criteria of the study. Data were analyzed using analysis Chi-square and multiple logistic regression. RESULTS: The results showed that maternal occupation (p = 0.018; odds ratio [OR] = 6.091; confidence interval [CI] 95% 1.367–27.133) was significant for CED, whereas that education (p = 0.213; OR = 0.593; CI 95% 0.260–1.351) and income (p = 0.576; OR = 0.733; 95% CI 0.247–2.179) are not significant to CED. Based on multivariate analysis we found that the most influential factor was occupation (adjusted OR = 11.734, CI 95% 1.253–109.91). CONCLUSION: Based on the results of research and discussion, it can be concluded that work affects the CED in pregnant women, while maternal education and income have no effect on CED in pregnant women. Occupation is the most influential factor on the CED, women who do not work have a risk of 11.734 times experiencing CED compared to women who work.


2019 ◽  
Vol 2 (1) ◽  
pp. 34
Author(s):  
Sri Restu Tempali ◽  
Sumiaty Sumiaty

Basic Health Research in 2013 recorded the prevalence of SEZ in pregnant women nationally reaching 24.2 percent, an increase from 2010 (18.8 %%) and 2007 (10.9%). The prevalence of SEZs in Central Sulawesi Province in 2013 was 32.6%, higher than the National average. Nutritional status monitoring in Central Sulawesi Province reported a prevalence of KEK Risk in pregnant women in 2015 of 32.6%. Districts with the highest prevalence were consecutively in Banggai Kepulauan District (67.8%), Tojo Una-Una District (51.9%), Sigi District (46.4%), Donggala District (36.7%), and Palu City (35.4%). Midwives in providing services to the community, especially pregnant women, always strive to prepare pregnant women since the first contact during prenatal care provides counseling or education to every pregnant mother about nutritional needs during pregnancy. This study aims to determine the role of midwives education in preventing Chronic Energy Deficiency (SEZ) in pregnant women in Central Sulawesi Province. Observational research with astudy design crosectional. Sampling using the proportional random sampling technique with a total sample of 98 midwives in the working area of 4 selected districts, namely Banggai Islands District (15 samples), Sigi District (18 samples), Donggala District (25 samples) and Palu City (40 samples). The results of the study showed that the midwives who carried out the role of education to pregnant women in their regions mostly did not have the incidence of pregnant women with SEZ (83.1%). The results of theanalysis Chi-Square obtained a p-Value value of 0.041, which means that there is a relationship between the role of midwife education and prevention of SEZ events in pregnant


2020 ◽  
Vol 11 (1) ◽  
pp. 65-75
Author(s):  
Usep Rusependhi ◽  
Diah Mulyawati Utari

Babies born at LBW (Low Body Event) are at risk of disrupting the growth and development of the baby, as well as the occurrence of hypertension, heart disease and diabetes in old age. One of the factors causing LBW is the condition of CED (Chronic Energy Deficiency) experienced by mothers during pregnancy. The highest prevalence of LBW in Kuningan Regency in 2018 is in the working area of the Manggari Community Health Center, which is 11.8% with the prevalence of pregnant women CED 10.1%. The purpose of this study was to determine the relationship of maternal CED status during pregnancy with LBW events. The study design uses case control from cohort registers of pregnant women. The total sample of the study were 114 infants, consisting of 38 cases and 76 controls who met the inclusion and exclusion criteria. The results of the statistical analysis of the Chi-Square test, obtained p value = 0.002 and OR = 4.317 (95% CI: 1.776-10.495) which means that there is a significant relationship between the status of CED during pregnancy with LBW events, where pregnant women CED risk 4.317 times higher for LBW delivery compared to pregnant women who are not CED. The conclusion of this study is that there is a relationship between the status of CED of mothers during pregnancy with the incidence of LBW.


SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A405-A406
Author(s):  
W A Youngren ◽  
K Miller

Abstract Introduction The enigmatic nature of Posttrauma Nightmares (PTNs) has left research without an agreed upon operational definition. This is partially due to PTNs often containing well remembered content that is similar to the triggering trauma, but also manifesting as severe nighttime awakenings without a concise or remembered dream narrative. Given that recent research has linked episodes of Obstructive Sleep Apnea (OSA) to PTNs, this study aimed to examine if OSA could explain why some distressed awakenings occur without memory of nightmare content. Methods Participants included 36 trauma survivors who reported experiencing PTNs, recruited from a clinical referral or at a Veterans Affairs Hospital. Presence of OSA was captured from self-reports of previous polysomnography-based sleep study results. PTNs were measured via a self-report measure that assessed past month nightmare frequency and if the content was remembered upon awakening. Analysis included descriptive statistics and chi-square tests. Results Out of the group with a reported diagnosis of OSA (N = 8), 75% (n = 6) reported they did not remember the content of their nightmares upon awakening, whereas out of the group without a reported OSA diagnosis (N = 28), only 4% of participants (n = 1) reported not remembering the content of their nightmares. There was a significant difference between OSA diagnosis and remembering nightmare content (X2 = 57.83, p &lt; 0.001). Conclusion Individuals with diagnosed OSA commonly experienced nightmares that were often not remembered upon awakening, while the group without OSA most often remembered the content of their nightmares. Due to this relationship, it is possible that some PTNs experienced by the OSA group may instead be misinterpreted respiratory events. Understanding the relationship between OSA and PTNs is crucial for developing the most effective treatment course. Support None.


2020 ◽  
Vol 185 (7-8) ◽  
pp. e1222-e1228
Author(s):  
Lízia Felix Cotias de Mattos Oliveira ◽  
Robert P Lennon ◽  
John W Roman ◽  
John F Sullivan ◽  
Edmund A Milder

Abstract Introduction The Amazon River Basin is the largest and the most complex fluvial system in the world. The Brazilian government provides dental and medical care to the riverine populations in this region in part through medical assistance missions, conducted by four hospital ships. The Brazilian Navy invited U.S. Navy medical personnel to join the February 2019 mission aboard Navio de Assistência Hospitalar (NAsH) Carlos Chagas to provide care along the Madeira River. Materials and Methods In the course of providing primary care services, demographic, health, and dental data of the Madeira Riverine population were collected. Descriptive statistics were used to generate average health and dental data. Chi-square tests were used to compare population prevalence data. Linear regression was used to evaluate dental caries per patient with proximity to nearest large population center and village population. This project was approved by Naval Medical Center Portsmouth Institutional Review Board. Results The Madeira Riverine population has similar dental health to Brazilians living in urban centers. Their prevalence of hypertension and diabetes compared favorably with the U.S. averages (17.7% vs. 34.3% [P &lt; 0.001] and 3% vs. 9.4% [P &lt; 0.001], respectively). Based on the most prevalent ICD-10 code diagnoses, future missions can expect high volumes of patients with intestinal parasites, hypertension, common skin infections, women’s health concerns, and musculoskeletal complaints. Conclusions This study adds to the limited health data currently available on Brazilian Riverine populations. It demonstrates the effectiveness of the Hospital Assistance missions in providing dental care and documents some unique aspects of Riverine health that warrant further study.


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