Longitudinal Associations Between Device-Measured Physical Activity and Early Childhood Neurodevelopment

2021 ◽  
pp. 1-9
Author(s):  
Otávio Amaral de Andrade Leão ◽  
Gregore Iven Mielke ◽  
Pedro Curi Hallal ◽  
John Cairney ◽  
Jorge Mota ◽  
...  
Keyword(s):  
Physical Activity ◽  
Early Childhood ◽  
Confidence Interval ◽  
Regression Models ◽  
Response Characteristic ◽  
Birth Cohort Study ◽  
Linear Regression Models ◽  
Child Neurodevelopment ◽  
Longitudinal Associations ◽  
Activity Trajectory

Background: The aim of this study was to investigate longitudinal associations between physical activity and early childhood neurodevelopment. Methods: Data from 1673 children from the 2015 Pelotas (Brazil) birth cohort study were analyzed. Physical activity was measured using accelerometers on the wrist at ages 1, 2, and 4 years. Neurodevelopment was measured using the Battelle Development Inventory at age 4 years. Linear regression models were used to test trajectories and cumulative associations of physical activity with child neurodevelopment. Results: Of the 3 physical activity trajectories observed, children in the medium (β = 1.17; 95% confidence interval, 0.25 to 2.10) and high (β = 2.22; 95% confidence interval, 0.61 to 3.82) trajectories showed higher neurodevelopment scores than children in the lower activity trajectory. Cumulative analyses showed that children in the highest tertile of physical activity in all follow-ups presented a mean neurodevelopment score 4.57 (95% confidence interval, 2.63 to 6.51) higher than children in the lowest tertile in all follow-ups. All analyses showed a dose–response characteristic of association, with higher physical activity indicating higher neurodevelopment scores. Conclusions: Physical activity may be an important predictor of neurodevelopment through early childhood.

Physical activity accrued as part of public transport use in England

2018 ◽  
Vol 41 (2) ◽  
pp. 222-230 ◽  
Author(s):  
R Patterson ◽  
E Webb ◽  
C Millett ◽  
A A Laverty
Keyword(s):  
Physical Activity ◽  
Logistic Regression ◽  
Confidence Interval ◽  
Public Transport ◽  
Regression Models ◽  
Daily Life ◽  
Active Travel ◽  
Linear Regression Models ◽  
Physical Activity Guidelines ◽  
Logistic Regression Models

Abstract Background Walking and cycling for transport (active travel) is an important source of physical activity with established health benefits. However, levels of physical activity accrued during public transport journeys in England are unknown. Methods Using the English National Travel Survey 2010–14 we quantified active travel as part of public transport journeys. Linear regression models compared levels of physical activity across public transport modes, and logistic regression models compared the odds of undertaking 30 min a day of physical activity. Results Public transport users accumulated 20.5 min (95% confidence interval=19.8, 21.2) a day of physical activity as part of public transport journeys. Train users accumulated 28.1 min (26.3, 30.0) with bus users 16.0 min (15.3, 16.8). Overall, 34% (32%, 36%) of public transport users achieved 30 min a day of physical activity in the course of their journeys; 21% (19%, 24%) of bus users and 52% (47%, 56%) of train users. Conclusion Public transport use is an effective way to incorporate physical activity into daily life. One in three public transport users meet physical activity guidelines suggesting that shifts from sedentary travel modes to public transport could dramatically raise the proportion of populations achieving recommended levels of physical activity.

Challenging the Link Between Early Childhood Television Exposure and Later Attention Problems: A Multiverse Approach

2021 ◽  
pp. 095679762097165
Author(s):  
Matthew T. McBee ◽  
Rebecca J. Brand ◽  
Wallace E. Dixon
Keyword(s):  
Early Childhood ◽  
Regression Models ◽  
Propensity Score Analysis ◽  
Harmful Effect ◽  
Attention Problems ◽  
Linear Regression Models ◽  
Data Set ◽  
Logistic Regression Models ◽  
Score Analysis ◽  
Television Exposure

In 2004, Christakis and colleagues published an article in which they claimed that early childhood television exposure causes later attention problems, a claim that continues to be frequently promoted by the popular media. Using the same National Longitudinal Survey of Youth 1979 data set ( N = 2,108), we conducted two multiverse analyses to examine whether the finding reported by Christakis and colleagues was robust to different analytic choices. We evaluated 848 models, including logistic regression models, linear regression models, and two forms of propensity-score analysis. If the claim were true, we would expect most of the justifiable analyses to produce significant results in the predicted direction. However, only 166 models (19.6%) yielded a statistically significant relationship, and most of these employed questionable analytic choices. We concluded that these data do not provide compelling evidence of a harmful effect of TV exposure on attention.

scholarly journals Validity, reliability, and calibration of the physical activity unit 7 item screener (PAU-7S) at population scale

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Helmut Schröder ◽  
Isaac Subirana ◽  
Julia Wärnberg ◽  
María Medrano ◽  
Marcela González-Gross ◽  
...  
Keyword(s):  
Physical Activity ◽  
Predictive Validity ◽  
Internal Consistency ◽  
Regression Models ◽  
Weighted Kappa ◽  
Linear Regression Models ◽  
Retest Reliability ◽  
Activity Unit ◽  
Test Retest Reliability ◽  
Acceptable Internal Consistency

Abstract Background Validation of self-reported tools, such as physical activity (PA) questionnaires, is crucial. The aim of this study was to determine test-retest reliability, internal consistency, and the concurrent, construct, and predictive validity of the short semi-quantitative Physical Activity Unit 7 item Screener (PAU-7S), using accelerometry as the reference measurement. The effect of linear calibration on PAU-7S validity was tested. Methods A randomized sample of 321 healthy children aged 8–16 years (149 boys, 172 girls) from the nationwide representative PASOS study completed the PAU-7S before and after wearing an accelerometer for at least 7 consecutive days. Weight, height, and waist circumference were measured. Cronbach alpha was calculated for internal consistency. Test-retest reliability was determined by intra-class correlation (ICC). Concurrent validity was assessed by ICC and Spearman correlation coefficient between moderate to vigorous PA (MVPA) derived by the PAU-7S and by accelerometer. Concordance between both methods was analyzed by absolute agreement, weighted kappa, and Bland-Altman statistics. Multiple linear regression models were fitted for construct validity and predictive validity was determined by leave-one-out cross-validation. Results The PAU-7S overestimated MVPA by 18%, compared to accelerometers (106.5 ± 77.0 vs 95.2 ± 33.2 min/day, respectively). A Cronbach alpha of 0.76 showed an acceptable internal consistency of the PAU-7S. Test-retest reliability was good (ICC 0.71 p < 0.001). Spearman correlation and ICC coefficients of MVPA derived by the PAU-7S and accelerometers increased from 0.31 to 0.62 and 0.20 to 0.62, respectively, after calibration of the PAU-7S. Between-methods concordance improved from a weighted kappa of 0.24 to 0.50 after calibration. A slight reduction in ICC, from 0.62 to 0.60, yielded good predictive validity. Multiple linear regression models showed an inverse association of MVPA with standardized body mass index (β − 0.162; p < 0.077) and waist to height ratio (β − 0.010; p < 0.014). All validity dimensions were somewhat stronger in boys compared to girls. Conclusion The PAU-7S shows a good test-retest reliability and acceptable internal consistency. All dimensions of validity increased from poor/fair to moderate/good after calibration. The PAU-7S is a valid instrument for measuring MVPA in children and adolescents. Trial registration Trial registration numberISRCTN34251612.

scholarly journals Isotonic quadriceps endurance is better associated with daily physical activity than quadriceps strength and power in COPD: an international multicentre cross-sectional trial

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Erik Frykholm ◽  
Sarah Gephine ◽  
Didier Saey ◽  
Arthur Lemson ◽  
Peter Klijn ◽  
...  
Keyword(s):  
Physical Activity ◽  
Linear Regression ◽  
Multiple Linear Regression ◽  
Regression Models ◽  
Sedentary Time ◽  
Quadriceps Strength ◽  
Linear Regression Models ◽  
Cross Sectional ◽  
Quadriceps Function ◽  
Multiple Linear Regression Models

AbstractKnowledge about modifiable determinants of daily physical activity (PA) in patients with chronic obstructive pulmonary disease (COPD) is crucial to design effective PA interventions. The present study aimed to determine the contribution of quadriceps strength, power and endurance to daily PA in COPD. Additionally, for quadriceps endurance, we also aimed to determine to what extent the association varies according to the mode of movement (isotonic, isometric, or isokinetic). Using a multicentre cross-sectional trial design we determined the contribution of quadriceps function to daily PA (steps, sedentary time and time spent doing moderate-to-very-vigorous physical activity [MVPA]) using bivariate and partial Pearson correlation analysis (r) and multiple linear regression models (ΔR2). Pre-determined controlling factors were sex, age, body mass index (BMI), COPD-assessment test, forced expiratory volume in one second in percent of the predicted value (FEV1pred), and distance walked on the 6-minute walk test. Eighty-one patients with COPD (mean ± SD: age 67 ± 8 years, FEV1pred 57 ± 19%, daily steps 4968 ± 3319, daily sedentary time 1016 ± 305 min, and MVPA time 83 ± 45 min) were included. Small to moderate bivariate correlations (r = .225 to .452, p < .05) were found between quadriceps function and measures of PA. The best multiple linear regression models explained 38–49% of the variance in the data. Isotonic endurance was the only muscle contributor that improved all PA models; daily steps (ΔR2 = .04 [relative improvement 13%] p = .026), daily sedentary time (ΔR2 = .07 [23%], p = .005) and MVPA-minutes (ΔR2 = .08 [20%], p = .001). Isotonic endurance was also independently associated with most PA variables, even when controlling for strength, power or isometric-isokinetic endurance properties of the muscle (r = .246 to .384, p < .05). In contrast, neither strength, power, isometric-or isokinetic endurance properties of the muscle was independently associated with PA measures when controlling for isotonic endurance (r = .037 to .219, p > .05). To conclude, strength, power, and endurance properties of the quadriceps were low to moderately associated with PA in patients with COPD. Isotonic quadriceps endurance was the only quadriceps property that was independently associated with the different measures of PA after controlling for a basic set of known determinants of PA, quadriceps strength or power, or isometric or isokinetic quadriceps endurance. Future longitudinal studies should investigate its potential as a modifiable determinant of PA.

Relationship Between Mental Health, Resilience, and Physical Activity in Older Adults: A 2-Year Longitudinal Study

2021 ◽  
pp. 1-9
Author(s):  
Maria Priscila Wermelinger Ávila ◽  
Jimilly Caputo Corrêa ◽  
Alessandra Lamas Granero Lucchetti ◽  
Giancarlo Lucchetti
Keyword(s):  
Mental Health ◽  
Physical Activity ◽  
Older Adults ◽  
Regression Models ◽  
Linear Regression Models ◽  
Physically Active ◽  
Effective Interventions ◽  
Self Sufficiency ◽  
The Relationship

The aim of this study was to longitudinally investigate the association between resilience and mental health in older adults and to determine the influence of physical activity on this relationship. A total of 291 older adults were included in a 2-year follow-up study. Adjusted linear regression models evaluated the association between resilience at baseline and mental health after 2 years in sufficiently and insufficiently physically active older adults. A negative correlation was found between resilience at baseline and depression, anxiety, and stress after 2 years for the overall sample. This association changed after stratifying the group. Sufficiently physically active individuals made greater use of the resilience components “Self-Sufficiency” and “Perseverance,” whereas insufficiently physically active individuals made greater use of “Meaning of Life” and “Existential Singularity.” Physical activity can influence the relationship between resilience and mental health. These results can help guide the devising of more effective interventions for this age group.

scholarly journals Delirium symptoms are associated with decline in cognitive function between ages 53 to 69: findings from a British birth cohort study

2017 ◽  
Author(s):  
A Tsui ◽  
D Kuh ◽  
M Richards ◽  
D Davis
Keyword(s):  
Birth Cohort ◽  
Verbal Memory ◽  
Regression Models ◽  
Cognitive Outcomes ◽  
Birth Cohort Study ◽  
Linear Regression Models ◽  
Cognitive Domains ◽  
Time Period ◽  
Search Speed ◽  
Addenbrooke’S Cognitive Examination

AbstractINTRODUCTIONFew population studies have investigated whether longitudinal decline after delirium in mid-to-late life might affect specific cognitive domains.METHODSParticipants from a birth cohort completing assessments of search speed, verbal memory and the Addenbrooke’s Cognitive Examination at age 69 were asked about delirium symptoms between ages 60-69. Linear regression models estimated associations between delirium symptoms and cognitive outcomes.RESULTSPeriod prevalence of delirium between 60 and 69 was 4% (95% CI 3.2%,4.9%). Self-reported symptoms of delirium over the seventh decade were associated with worse scores in the Addenbrooke’s Cognitive Examination (−1.7 points, 95% CI −3.2, −0.1, p=0.04). In association with delirium symptoms, verbal memory scores were initially lower, with subsequent decline in search speed by age 69. These effects were independent of other Alzheimer’s risk factors.DISCUSSIONDelirium symptoms may be common even at relatively younger ages, and their presence may herald cognitive decline, particularly in search speed, over this time period.

scholarly journals Driving status, travel modes and accelerometer-assessed physical activity in younger, middle-aged and older adults: a prospective study of 90 810 UK Biobank participants

2019 ◽  
Vol 48 (4) ◽  
pp. 1175-1186 ◽  
Author(s):  
Samantha Hajna ◽  
Tom White ◽  
Jenna Panter ◽  
Søren Brage ◽  
Katrien Wijndaele ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Mixed Mode ◽  
Regression Models ◽  
Motor Vehicle ◽  
Uk Biobank ◽  
Linear Regression Models ◽  
Optimal Activity ◽  
Vigorous Intensity ◽  
A Prospective Study

Abstract Background Associations between driving and physical-activity (PA) intensities are unclear, particularly among older adults. We estimated prospective associations of travel modes with total PA, sedentary time (ST), light-intensity PA (LPA), and moderate-to-vigorous intensity PA (MVPA) among adults aged 39–70 years. Methods We studied 90 810 UK Biobank participants (56.1 ± 7.8 years). Driving status, specific travel modes (non-work travel; commuting to/from work) and covariates were assessed by questionnaire (2006–10). PA was assessed over 7 days by wrist-worn accelerometers (2013–15). We estimated associations using overall and age-stratified multivariable linear-regression models. Results Drivers accumulated 1.4% more total PA (95% confidence interval: 0.9, 1.9), 11.2 min/day less ST (–12.9, –9.5), 12.2 min/day more LPA (11.0, 13.3) and 0.9 min/day less MVPA (–1.6, –0.2) than non-drivers. Compared with car/motor-vehicle users, cyclists and walkers had the most optimal activity profiles followed by mixed-mode users (e.g. for non-work travel, cyclists: 10.7% more total PA, 9.0, 12.4; 20.5 min/day less ST, –26.0, –15.0; 14.5 min/day more MVPA, 12.0, 17.2; walkers: 4.2% more total PA, 3.5, 5.0; 7.5 min/day less ST –10.2, –4.9; 10.1 min/day more MVPA, 8.9, 11.3; mixed-mode users: 2.3% more total PA, 1.9, 2.7; 3.4 min/day less ST –4.8, –2.1; 4.9 min/day more MVPA, 4.3, 5.5). Some associations varied by age (p interaction &lt; 0.05), but these differences appeared small. Conclusions Assessing specific travel modes rather than driving status alone may better capture variations in activity. Walking, cycling and, to a lesser degree, mixed-mode use are associated with more optimal activity profiles in adults of all ages.

Behavior Tracking and 3-Year Longitudinal Associations Between Physical Activity, Screen Time, and Fitness Among Young Children

2018 ◽  
Vol 30 (1) ◽  
pp. 132-141 ◽  
Author(s):  
Morgan Potter ◽  
John C. Spence ◽  
Normand Boulé ◽  
Jodie A. Stearns ◽  
Valerie Carson
Keyword(s):  
Physical Activity ◽  
Young Children ◽  
Grip Strength ◽  
Screen Time ◽  
Regression Models ◽  
Vertical Jump ◽  
Multiple Regression Models ◽  
Longitudinal Associations ◽  
Behavior Tracking

Purpose: Understanding the correlates of children’s fitness as they develop is needed. The objectives of this study were to 1) examine the longitudinal associations between physical activity (PA), screen time (ST), and fitness; 2) determine if sex moderates associations; and 3) track PA and ST over 3 years. Methods: Findings are based on 649 children [baseline = 4.5 (0.5) y; follow-up = 7.8 (0.6) y] from Edmonton, Canada. Parental-reported hour per week of PA and ST were measured at baseline and 3 years later. Fitness (vertical jump, sit and reach, waist circumference, grip strength, predicted VO2max, push-ups, and partial curl-ups) was measured using established protocols at follow-up. Sex-specific z scores or low/high fitness groups were calculated. Linear or logistic multiple regression models and Spearman correlations were conducted. Results: Baseline ST was negatively associated with follow-up grip strength [β = −0.010; 95% confidence interval (CI), −0.019 to −0.001]. Associations between baseline PA and follow-up overall fitness (β = 0.009; 95% CI, 0.002 to 0.016) were significant, whereas baseline PA and follow-up VO2max (β = 0.014; 95% CI, 0.000 to 0.027) approached significance (P < .06). No sex interactions were observed. Moderate and large tracking were observed for PA (rs = .30) and ST (rs = .53), respectively. Conclusions: PA and ST may be important modifiable correlates of overall fitness in young children.

scholarly journals The Influence of Sitting, Standing, and Stepping Bouts on Cardiometabolic Health Markers in Older Adults

2021 ◽  
pp. 1-9
Author(s):  
Simone J.J.M. Verswijveren ◽  
Cormac Powell ◽  
Stephanie E. Chappel ◽  
Nicola D. Ridgers ◽  
Brian P. Carson ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Body Composition ◽  
Linear Regression ◽  
Regression Models ◽  
Fasting Glucose ◽  
Cardiometabolic Health ◽  
Linear Regression Models ◽  
Cross Sectional

Aside from total time spent in physical activity behaviors, how time is accumulated is important for health. This study examined associations between sitting, standing, and stepping bouts, with cardiometabolic health markers in older adults. Participants from the Mitchelstown Cohort Rescreen Study (N = 221) provided cross-sectional data on activity behaviors (assessed via an activPAL3 Micro) and cardiometabolic health. Bouts of ≥10-, ≥30-, and ≥60-min sitting, standing, and stepping were calculated. Linear regression models were fitted to examine the associations between bouts and cardiometabolic health markers. Sitting (≥10, ≥30, and ≥60 min) and standing (≥10 and ≥30 min) bouts were detrimentally associated with body composition measures, lipid markers, and fasting glucose. The effect for time spent in ≥60-min sitting and ≥30-min standing bouts was larger than shorter bouts. Fragmenting sitting with bouts of stepping may be targeted to benefit cardiometabolic health. Further insights for the role of standing need to be elicited.

scholarly journals Association Between Ov16 Seropositivity and Neurocognitive Performance Among Children in Rural Cameroon: a Pilot Study

2021 ◽  
Author(s):  
Joseph Nelson Siewe Fodjo ◽  
Wepnyu Y. Njamnshi ◽  
Leonard Ngarka ◽  
Leonard N. Nfor ◽  
Constance Ayuk ◽  
...  
Keyword(s):  
Confidence Interval ◽  
Verbal Fluency ◽  
Regression Models ◽  
Linear Regression Models ◽  
Neurocognitive Performance ◽  
Anthropometric Parameters ◽  
School Aged Children ◽  
Gender Education ◽  
Rural Cameroon ◽  
Scale Estimate

AbstractInfection with Onchocerca volvulus was recently reported to increase the risk for epilepsy in Cameroonian children. We investigated whether infection with O. volvulus may alter the cognitive function of children who may or may not develop epilepsy later in their lifetime. Using rapid diagnostic tests, we determined the presence of Ov16 antibodies in 209 school-aged children without epilepsy recruited from three Cameroonian villages, as a proxy for onchocerciasis exposure. In addition, the neurocognitive performance of these children was assessed using a battery of validated tools. Participants were aged 6–16 years, and 46.4% were Ov16 seropositive. Upon standardizing age-specific neurocognitive scores and investigating predictors of neurocognitive performance using multiple linear regression models (adjusted for gender, education level, previous ivermectin use, and anthropometric parameters), we found that being Ov16-positive was significantly associated with reduced semantic verbal fluency (estimate –0.38; 95% confidence interval –0.65 to –0.11; p = 0.006) and lower scores on the International HIV Dementia Scale (estimate –0.31; confidence interval –0.56 to –0.04; p = 0.025). Furthermore, an increasing frequency of past ivermectin use was associated with increased neurocognitive scores. Our findings suggest that exposure to O. volvulus may affect neurocognitive performance of children.

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