Antigenic characterization of Helicobacter pylori strains from different parts of the world.

1997 ◽  
Vol 4 (5) ◽  
pp. 592-597 ◽  
Author(s):  
J Höök-Nikanne ◽  
G I Perez-Perez ◽  
M J Blaser
Keyword(s):  
Helicobacter Pylori ◽  
Antigenic Characterization ◽  
The World ◽  
Different Parts

scholarly journals Integrated stratigraphy of the Upper Barremian–Aptian sediments from the south-eastern Crimea

2018 ◽  
Vol 69 (5) ◽  
pp. 498-511 ◽  
Author(s):  
Maria S. Karpuk ◽  
Ekaterina A. Shcherbinina ◽  
Ekaterina A. Brovina ◽  
Galina N. Aleksandrova ◽  
Andrey Yu. Guzhikov ◽  
...  
Keyword(s):  
Planktonic Foraminifera ◽  
Calcareous Nannofossils ◽  
South Eastern ◽  
The World ◽  
Eastern Crimea ◽  
Integrated Study ◽  
Different Parts ◽  
Made In ◽  
Biostratigraphic Units

Abstract Previous studies made in different parts of the world have shown that Barremian–Aptian times imply many difficulties in deciphering the biostratigraphy, microfossil evolution and correlation of bioevents. In an attempt to improve our knowledge of this period in a particular area of the Tethyan realm, we present the first integrated study of microbiota (including planktonic foraminifera, calcareous nannofossils, ostracods and palynomorphs) and magnetostratigraphy of the upper Barremian–Aptian sediments from south-eastern Crimea. The nannofossils display the classical Tethyan chain of bioevents in this interval, while the planktonic foraminifera demonstrate an incomplete succession of stratigraphically important taxa. Our study enabled the recognition of a series of biostratigraphic units by means of four groups of microfossils correlated to polarity chrons. The detailed analysis of the microfossil distribution led to a biostratigraphic characterization of the Barremian/Aptian transition and brought to light an interval, which may correspond to the OAE1a.

scholarly journals Structure to function analysis with antigenic characterization of a hypothetical protein, HPAG1_0576 from Helicobacter pylori HPAG1

2019 ◽  
Vol 15 (7) ◽  
pp. 456-466 ◽  
Author(s):  
Hanan Ashrafi ◽  
◽  
Muntequa Ishtiaq Siraji ◽  
Nazmir Nur Showva ◽  
Md. Mozammel Hossain ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Function Analysis ◽  
Hypothetical Protein ◽  
Antigenic Characterization

BIOASSAY CHARACTERISTICS OF INDIVIDUAL URINARY GONADOTROPHIN EXTRACTS

1963 ◽  
Vol 42 (2) ◽  
pp. 214-224
Author(s):  
Raymond C. Mellinger ◽  
Jalileh A. Mansour ◽  
Richmond W. Smith
Keyword(s):  
Reference Material ◽  
Young Women ◽  
Reference Standard ◽  
General Acceptance ◽  
Modifying Factors ◽  
Large Numbers ◽  
The World ◽  
Quantitative Bioassay ◽  
Different Parts ◽  
Age And Sex

ABSTRACT A reference standard is widely sought for use in the quantitative bioassay of pituitary gonadotrophin recovered from urine. The biologic similarity of pooled urinary extracts obtained from large numbers of subjects, utilizing groups of different age and sex, preparing and assaying the materials by varying techniques in different parts of the world, has lead to a general acceptance of such preparations as international gonadotrophin reference standards. In the present study, however, the extract of pooled urine from a small number of young women is shown to produce a significantly different bioassay response from that of the reference materials. Gonadotrophins of individual subjects likewise varied from the multiple subject standards in many instances. The cause of these differences is thought to be due to the modifying influence of non-hormonal substances extracted from urine with the gonadotrophin and not necessarily to variations in the gonadotrophins themselves. Such modifying factors might have similar effects in a comparative assay of pooled extracts contributed by many subjects, but produce significant variations when material from individual subjects is compared. It is concluded that the expression of potency of a gonadotrophic extract in terms of pooled reference material to which it is not essentially similar may diminish rather than enhance the validity of the assay.

Christianity in the Twentieth Century

2019 ◽  
Author(s):  
Brian Stanley
Keyword(s):  
Latin America ◽  
Racial Identity ◽  
Sub Saharan Africa ◽  
Central Importance ◽  
Regional Survey ◽  
History Of Christianity ◽  
The World ◽  
History Of ◽  
Sub Saharan ◽  
Different Parts

This book charts the transformation of one of the world's great religions during an age marked by world wars, genocide, nationalism, decolonization, and powerful ideological currents, many of them hostile to Christianity. The book traces how Christianity evolved from a religion defined by the culture and politics of Europe to the expanding polycentric and multicultural faith it is today—one whose growing popular support is strongest in sub-Saharan Africa, Latin America, China, and other parts of Asia. The book sheds critical light on themes of central importance for understanding the global contours of modern Christianity, illustrating each one with contrasting case studies, usually taken from different parts of the world. Unlike other books on world Christianity, this one is not a regional survey or chronological narrative, nor does it focus on theology or ecclesiastical institutions. The book provides a history of Christianity as a popular faith experienced and lived by its adherents, telling a compelling and multifaceted story of Christendom's fortunes in Europe, North America, and across the rest of the globe. It demonstrates how Christianity has had less to fear from the onslaughts of secularism than from the readiness of Christians themselves to accommodate their faith to ideologies that privilege racial identity or radical individualism.

THE 2019 NOVEL PANDEMIC OF CORONAVIRUS DISEASE (COVID-19): A STUDY OF EXISTING EVIDENCE IN THE INDIAN POPULATION

2020 ◽  
Vol 7 (2) ◽  
pp. 199-204
Author(s):  
Shrikant Verma ◽  
Mohammad Abbas ◽  
Sushma Verma ◽  
Syed Tasleem Raza ◽  
Farzana Mahdi
Keyword(s):  
Disease Transmission ◽  
Indian Population ◽  
Respiratory Infections ◽  
Clinical Signs ◽  
Case Fatality ◽  
Public Health Emergency ◽  
The World ◽  
And Control ◽  
General Wellbeing ◽  
Different Parts

A novel spillover coronavirus (nCoV), with its epicenter in Wuhan, China's People's Republic, has emerged as an international public health emergency. This began as an outbreak in December 2019, and till November eighth, 2020, there have been 8.5 million affirmed instances of novel Covid disease2019 (COVID-19) in India, with 1,26,611 deaths, resulting in an overall case fatality rate of 1.48 percent. Coronavirus clinical signs are fundamentally the same as those of other respiratory infections. In different parts of the world, the quantity of research center affirmed cases and related passings are rising consistently. The COVID- 19 is an arising pandemic-responsible viral infection. Coronavirus has influenced huge parts of the total populace, which has prompted a global general wellbeing crisis, setting all health associations on high attentive. This review sums up the overall landmass, virology, pathogenesis, the study of disease transmission, clinical introduction, determination, treatment, and control of COVID-19 with the reference to India.

Jiangnan Style

2017 ◽  
Author(s):  
Chris Wickham
Keyword(s):  
Middle Ages ◽  
Economic Activity ◽  
Global Economy ◽  
Medieval Period ◽  
The World ◽  
Transnational Connections ◽  
New Research ◽  
Different Parts

Building on impressive new research into the concept of a ‘global middle ages’, this chapter offers insights into how economic formations developed around the world. Drawing on new research on both Chinese and Mediterranean economies in the ‘medieval’ period, it compares structures of economy and exchange in very different parts of the world. The point of such comparisons is not simply to find instances of global economic flows but to understand the logic of medieval economic activity and its intersections with power and culture; and, in so doing, to remind historians that economic structures, transnational connections, and the imbrications of economy and politics do not arrive only with modernity, nor is the shape of the ‘modern’ global economy the only pattern known to humankind.

scholarly journals The absence of the caffeine synthase gene is involved in the naturally decaffeinated status of Coffea humblotiana, a wild species from Comoro archipelago

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Nathalie Raharimalala ◽  
Stephane Rombauts ◽  
Andrew McCarthy ◽  
Andréa Garavito ◽  
Simon Orozco-Arias ◽  
...  
Keyword(s):  
Wild Species ◽  
Illegitimate Recombination ◽  
Recombination Mechanism ◽  
Comparative Analyses ◽  
Robusta Coffee ◽  
Caffeine Synthase ◽  
The World ◽  
Decaffeinated Coffee ◽  
Chromosome Level

AbstractCaffeine is the most consumed alkaloid stimulant in the world. It is synthesized through the activity of three known N-methyltransferase proteins. Here we are reporting on the 422-Mb chromosome-level assembly of the Coffea humblotiana genome, a wild and endangered, naturally caffeine-free, species from the Comoro archipelago. We predicted 32,874 genes and anchored 88.7% of the sequence onto the 11 chromosomes. Comparative analyses with the African Robusta coffee genome (C. canephora) revealed an extensive genome conservation, despite an estimated 11 million years of divergence and a broad diversity of genome sizes within the Coffea genus. In this genome, the absence of caffeine is likely due to the absence of the caffeine synthase gene which converts theobromine into caffeine through an illegitimate recombination mechanism. These findings pave the way for further characterization of caffeine-free species in the Coffea genus and will guide research towards naturally-decaffeinated coffee drinks for consumers.

The Struggle for Public Recognition: Understanding Early Marriage through the Lens of Honour and Shame in Six Countries in South Asia and West Africa

2020 ◽  
Vol 20 (4) ◽  
pp. 328-346
Author(s):  
Esther Miedema ◽  
Winny Koster ◽  
Nicky Pouw ◽  
Philippe Meyer ◽  
Albena Sotirova
Keyword(s):  
International Development ◽  
Female Sexuality ◽  
Social Economic ◽  
Early Marriage ◽  
Social Standing ◽  
Public Recognition ◽  
The World ◽  
Economic Future ◽  
Different Parts

There is a burgeoning body of research on the role of ‘shame’ and ‘honour’ in decisions regarding early marriage in different parts of the world. Conceptualizing shame and honour as idioms through which gendered socio-economic inequalities are created and maintained, we examine early marriage decisions in Bangladesh, Nepal, Pakistan, Ghana, Burkina Faso and Senegal. While we acknowledge the existence of important differences between countries in terms of the nature and manifestations of shame and honour, we argue that regardless of setting, neither shame and honour, nor female sexuality and chastity can be separated from the socio-economic hierarchies and inequalities. Thus, in this article we seek to identify the cross-cutting dynamic of marriage as a means to overcome the shame associated with young single women’s sexuality, protecting family honour and social standing, and/or securing young women’s social-economic future. Building on our data and available scholarship, we question the potential of emphasizing ‘choice’ as a means of reducing early marriage and advancing women’s emancipation in international development efforts. Instead, we argue in favour of initiatives that engage with young people and caregivers on the ways in which, at grassroot levels, communities may revise narratives of respectability, marriageability and social standing.

scholarly journals Antigenic Characterization of ORF2 and ORF3 Proteins of Hepatitis E Virus (HEV)

Viruses ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1385
Author(s):  
Giulia Pezzoni ◽  
Lidia Stercoli ◽  
Eleonora Pegoiani ◽  
Emiliana Brocchi
Keyword(s):  
Hepatitis E Virus ◽  
Hepatitis E ◽  
Recombinant Antigen ◽  
Open Reading Frame ◽  
Reading Frame ◽  
E Coli ◽  
Antigenic Characterization ◽  
Antigenic Properties ◽  
Open Reading Frame 2

To evaluate the antigenic properties of Hepatitis E Virus (HEV) Open Reading Frame 2 and 3 (ORF2 and ORF3) codified proteins, we expressed different portions of ORF2 and the entire ORF3 in E. coli, a truncated ORF2, was also expressed in baculovirus. A panel of 37 monoclonal antibodies (MAbs) was raised against ORF2 (1–660 amino acids) and MAbs were mapped and characterized using the ORF2 expressed portions. Selected HEV positive and negative swine sera were used to evaluate ORF2 and ORF3 antigens’ immunogenicity. The MAbs were clustered in six groups identifying six antigenic regions along the ORF2. Only MAbs binding to the sixth ORF2 antigenic region (394–608 aa) were found to compete with HEV positive sera and efficiently catch the recombinant antigen expressed in baculovirus. The ORF2 portion from 394–608 aa demonstrated to include most immunogenic epitopes with 85% of HEV positive swine sera reacting against the region from 461–544 aa. Only 5% of the selected HEV sera reacted against the ORF3 antigen.

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