scholarly journals Characterizing Microbiomes via Sequencing of Marker Loci: Techniques To Improve Throughput, Account for Cross-Contamination, and Reduce Cost

mSystems ◽  
2021 ◽  
Author(s):  
Joshua G. Harrison ◽  
Gregory D. Randolph ◽  
C. Alex Buerkle
Keyword(s):  
Best Practices ◽  
Study Design ◽  
Cross Contamination ◽  
New Methods ◽  
New Approaches ◽  
Marker Loci

New methods to characterize microbiomes reduce technology-imposed limitations to study design, but many new approaches have not been widely adopted. Here, we present techniques to increase throughput and reduce contamination alongside a thorough review of current best practices.

scholarly journals Alternatives to and Reduction of Animal Use in Biomedical Research, Education and Testing

1990 ◽  
Vol 18 (1_part_1) ◽  
pp. 65-74
Author(s):  
John M. Frazier ◽  
Alan M. Goldberg
Keyword(s):  
Biomedical Research ◽  
Toxicity Testing ◽  
Research Education ◽  
New Methods ◽  
New Approaches ◽  
The Future ◽  
Technological Developments ◽  
Animal Use ◽  
Do So

Biomedical endeavours can be divided into three major categories: research, education, and testing. Within the context of each of these categories, activities involving whole animals have made major contributions and will continue to do so in the future. However, with technological developments in the areas of biotechnology and computers, new methods are already reducing the use of whole animals in certain areas. This article discusses the general issues of alternatives and then focuses on the development of new approaches to toxicity testing.

scholarly journals Trends and Developments in Bioinformatics in 2010: Prospects and Perspectives

2011 ◽  
Vol 20 (01) ◽  
pp. 146-155
Author(s):  
A. V. Alekseyenko ◽  
Y. Aphinyanaphongs ◽  
S. Brown ◽  
D. Fenyo ◽  
L. Fu ◽  
...  
Keyword(s):  
Best Practices ◽  
Open Problems ◽  
The Past ◽  
New Methods ◽  
Methods Development ◽  
Long Term Trends ◽  
To Come ◽  
Generation Sequencing

SummaryTo survey major developments and trends in the field of Bioinformatics in 2010 and their relationships to those of previous years, with emphasis on long-term trends, on best practices, on quality of the science of informatics, and on quality of science as a function of informatics.A critical review of articles in the literature of Bioinformatics over the past year.Our main results suggest that Bioinformatics continues to be a major catalyst for progress in Biology and Translational Medicine, as a consequence of new assaying technologies, most predominantly Next Generation Sequencing, which are changing the landscape of modern biological and medical research. These assays critically depend on bioinformatics and have led to quick growth of corresponding informatics methods development. Clinical-grade molecular signatures are proliferating at a rapid rate. However, a highly publicized incident at a prominent university showed that deficiencies in informatics methods can lead to catastrophic consequences for important scientific projects. Developing evidence-driven protocols and best practices is greatly needed given how serious are the implications for the quality of translational and basic science.Several exciting new methods have appeared over the past 18 months, that open new roads for progress in bioinformatics methods and their impact in biomedicine. At the same time, the range of open problems of great significance is extensive, ensuring the vitality of the field for many years to come.

scholarly journals Intermittent Transfusions for Treatment of Thalassemia in the State of Georgia, 2007-2016

2021 ◽  
Vol 8 (4) ◽  
Author(s):  
Rollins MR ◽  
◽  
Boudreaux J ◽  
Eckman J ◽  
Branscomb J ◽  
...  
Keyword(s):  
Best Practices ◽  
Hospital Discharge ◽  
Study Design ◽  
Red Cell ◽  
Diagnosis Code ◽  
Provider Education ◽  
Discharge Data ◽  
Red Cell Transfusion ◽  
Transfusion Complications ◽  
Transfusion History

Background: Individuals with Non-Transfusion Dependent Thalassemia (NTDT) may require infrequent transfusions. Knowing transfusion history, while important, can be challenging in this subgroup. Study Design: Hospital discharge data in Georgia (2007-2016) was reviewed. Thalassemia patients were defined as ≥3 encounters with a thalassemia diagnosis code. Transfusion was defined by the presence of a diagnosis, CPT, revenue, or HCPCS code for red cell transfusion. Results: There were 428 patients identified; 57 received multi-site transfusions. Conclusion: Georgia hospitals provide intermittent transfusions to low volumes of probable NTDT patients. Patient and provider education may help assure adherence to best practices, avoiding serious transfusion complications.

GLBIMR, one of the premier B-schools of India, is organizing International Conference on “Innovations in Technology: A Roadmap for Achieving Global Competitiveness (ICIT-2K16)” on September 10, 2016, Saturday

2017 ◽  
Vol 8 (2) ◽  
pp. 63
Author(s):  
Editorial Board
Keyword(s):  
Sustainable Development ◽  
Best Practices ◽  
New Products ◽  
Business Value ◽  
Global Competitiveness ◽  
International Conference ◽  
Global Forum ◽  
New Methods ◽  
Course Of Action ◽  
New Ideas

International Conference (ICIT-2K16) aims to provide a global forum to present and discuss research on Innovations in Technological Fields among academicians and practitioners. Firms need to constantly evolve and explore new ideas for offering not only new products but also targeting new methods of production, new markets, sustainable development etc. Use of innovations in technology to create business value is multi-disciplinary. Conference endeavours to showcase research ideas from academia along with best practices by industry experts resulting in rich discussions and fuel future course of action.

Options and Prospects of Conceptual Approach Development for Managing Integrated Business Structures

Upravlenie ◽  
10.12737/2819 ◽  
2014 ◽  
Vol 2 (1) ◽  
pp. 57-60
Author(s):  
Мальчевский ◽  
A. Malchevskiy ◽  
Афанасьев ◽  
Valentin Afanasev
Keyword(s):  
Large Scale ◽  
Conceptual Approach ◽  
Bank Holding Company ◽  
Holding Company ◽  
Solid Ground ◽  
New Methods ◽  
New Approaches ◽  
Business Structures ◽  
Integrated Structures

Application of new methods for managing large-scale integrated structures are considered as exemplified by the bank holding company. The factors urging the use of new approaches are highlighted. The author gives solid ground for options and prospects for development of conceptual approach, ensuring consistency of goals and enhancing integration of a holding company’s components.

scholarly journals A benchmark of Spanish language datasets for computationally driven research

2021 ◽  
pp. 016555152110605
Author(s):  
Gustavo Candela ◽  
María-Dolores Sáez ◽  
Pilar Escobar ◽  
Manuel Marco-Such
Keyword(s):  
Spanish Text ◽  
Best Practices ◽  
Latin American ◽  
Linguistic Diversity ◽  
User Engagement ◽  
Digital Collections ◽  
Cultural And Linguistic Diversity ◽  
New Methods ◽  
Text Corpora ◽  
International Attention

In the domain of Galleries, Libraries, Archives and Museums (GLAM) institutions, creative and innovative tools and methodologies for content delivery and user engagement have recently gained international attention. New methods have been proposed to publish digital collections as datasets amenable to computational use. Standardised benchmarks can be useful to broaden the scope of machine-actionable collections and to promote cultural and linguistic diversity. In this article, we propose a methodology to select datasets for computationally driven research applied to Spanish text corpora. This work seeks to encourage Spanish and Latin American institutions to publish machine-actionable collections based on best practices and avoiding common mistakes.

scholarly journals New Methods for Reducing the Problems of Photovoltaic Systems

2015 ◽  
Vol 16 (1) ◽  
pp. 13
Author(s):  
Sobhan Dorahaki
Keyword(s):  
Renewable Energy ◽  
Renewable Energy Sources ◽  
Environmental Pollutants ◽  
Energy Sources ◽  
Photovoltaic Systems ◽  
Renewable Source ◽  
New Methods ◽  
New Approaches ◽  
The World ◽  
Made In

Increasing of demand in the energy sphere and also unprecedented proliferation of environmental pollutants in the air has pushed human toward the using of renewable energy sources such as photovoltaic systems. Unfortunately, despite all the efforts made, in the field of photovoltaic systems, still the usability of this clean and renewable source is skeptical in the world. This paper examines some basic problems of photovoltaic systems and discusses a few new approaches to reduce some problems of photovoltaic systems. The proposed approaches have capabilities and difficulties which are investigated in this study.

World Englishes and Dialectology

2014 ◽  
Author(s):  
Lieselotte Anderwald
Keyword(s):  
United States ◽  
Comparative Study ◽  
The United States ◽  
World Englishes ◽  
Morphosyntactic Variation ◽  
New Methods ◽  
New Approaches ◽  
The Comparative Study

This chapter summarizes new approaches to the study of traditional dialects, in particular in Britain and the United States, and discusses how new methods, new results, and new topics of investigation may inform and enrich the study of World Englishes, too. Of particular importance may be the acknowledgement of widespread variability in the ‘homeland’ that is increasingly also historically attested and sociolinguistically described, the study of morphosyntactic variation as an area of language that seems to remain quite stable under settlement conditions, and the comparative study of present-day variability that indicates the breadth (and limits) of variability. In return, results from the comparative study of World Englishes also have the potential to enrich modern dialectology and sociolinguistics.

scholarly journals A Customizable Analysis Flow in Integrative Multi-Omics

Biomolecules ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 1606
Author(s):  
Samuel M. Lancaster ◽  
Akshay Sanghi ◽  
Si Wu ◽  
Michael P. Snyder
Keyword(s):  
Machine Learning ◽  
Mass Spectrometry ◽  
Systems Biology ◽  
Nucleic Acid ◽  
Best Practices ◽  
Data Integration ◽  
Study Design ◽  
Molecular Interactions ◽  
Analysis Workflow ◽  
Integration Techniques

The number of researchers using multi-omics is growing. Though still expensive, every year it is cheaper to perform multi-omic studies, often exponentially so. In addition to its increasing accessibility, multi-omics reveals a view of systems biology to an unprecedented depth. Thus, multi-omics can be used to answer a broad range of biological questions in finer resolution than previous methods. We used six omic measurements—four nucleic acid (i.e., genomic, epigenomic, transcriptomics, and metagenomic) and two mass spectrometry (proteomics and metabolomics) based—to highlight an analysis workflow on this type of data, which is often vast. This workflow is not exhaustive of all the omic measurements or analysis methods, but it will provide an experienced or even a novice multi-omic researcher with the tools necessary to analyze their data. This review begins with analyzing a single ome and study design, and then synthesizes best practices in data integration techniques that include machine learning. Furthermore, we delineate methods to validate findings from multi-omic integration. Ultimately, multi-omic integration offers a window into the complexity of molecular interactions and a comprehensive view of systems biology.

scholarly journals New Approaches to the Direct Measurement of Capacitance

1977 ◽  
Vol 4 (1) ◽  
pp. 37-42 ◽  
Author(s):  
M. S. Raven ◽  
D. Raven
Keyword(s):  
Direct Measurement ◽  
New Methods ◽  
New Approaches ◽  
Measuring Techniques ◽  
Interface Capacitance

The limitations of conventional a.c. capacitance measuring techniques, for such measurements as MIS interface capacitance and measurements of large value electrolytics, has lead to a demand for new methods of capacitance measuring. This article reviews two new approaches which are presently being employed – the quadrature P.S.D. technique and time encoded ballistic techniques.

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