scholarly journals SARS-CoV-2 Antibody Testing in Health Care Workers: A Comparison of the Clinical Performance of Three Commercially Available Antibody Assays

2021 ◽  
Author(s):  
Niamh Allen ◽  
Melissa Brady ◽  
Antonio Isidro Carrion Martin ◽  
Lisa Domegan ◽  
Cathal Walsh ◽  
...  
Keyword(s):  
Public Health ◽  
Health Care Workers ◽  
Clinical Performance ◽  
Antibody Testing ◽  
Antibody Assay ◽  
Relative Paucity ◽  
Care Workers ◽  
Antibody Assays ◽  
Important Quality ◽  
Over Time

As the COVID-19 pandemic progresses, retained sensitivity over time is an important quality in an antibody assay that is to be used for the purpose of population seroprevalence studies. There is a relative paucity of published literature in this field to help guide public health specialists when planning seroprevalence studies.

scholarly journals Analytical and Clinical Analysis of Two Automated Anti-SARS-CoV-2 Immunoassays in Pre-Pandemic and Pandemic Patient Populations

2020 ◽  
Author(s):  
Jianbo Yang ◽  
Edward C Pederson ◽  
Christopher Hamilton ◽  
Terri Neibauer ◽  
Kimberly Robyak ◽  
...  
Keyword(s):  
Public Health ◽  
Sensitivity And Specificity ◽  
Laboratory Tests ◽  
Clinical Performance ◽  
Effective Vaccine ◽  
Clinical Settings ◽  
Rt Pcr ◽  
Antibody Testing ◽  
Antibody Assays ◽  
Positive Controls

Abstract Background In the absence of a safe, effective vaccine, the worldwide spread of COVID-19 (SARS-CoV-2) infection will continue. Laboratory tests with ideal precision, sensitivity, and specificity should be used in public health and clinical settings to gauge the extent of virus exposure. Toward this end, we evaluated the analytical and clinical performance of the Abbott SARS-CoV-2 IgG and the Roche Anti-SARS-CoV-2 immunoassays. Methods Quality control, pooled COVID-19, and non-COVID-19 patient specimens were used for the imprecision study. Two hundred and forty-six specimens from 70 patients with COVID-19 diagnosis were tested to study the sensitivity. Seventy-three non-COVID-19 control specimens were measured to study the specificity. All specimens were analyzed by both assays. Results Total analytic variability (CV) of the negative and positive controls were 5.5% and 3.6% for the Abbott assay and 4.5% and 1.9% for the Roche assay. Both assays demonstrated 100% qualitative reproducibility of negative and positive controls. The clinical specificities of the Abbott and the Roche assays were 100% (95% CI: 94%—100%) and 97% (95% CI: 90%—100%), respectively. The clinical sensitivities of the Abbott assay were 49% (95% CI: 41%—56%), 86% (95% CI: 74%—93%), and 100% (95% CI: 76%—100%) for samples collected at 0–6 days, 7–13 days, and ≥14 days after the first RT-PCR, while the sensitivities of the Roche assay were 55% (95% CI: 47%—62%), 86% (95% CI: 74%—93%), and 100% (95% CI: 76%—100%). Conclusions This study demonstrates similar analytical and clinical performance of the Abbott and the Roche SARS-CoV-2 antibody assays, but the Roche assay may be slightly more sensitive for patients tested within 0–6 days after first positive RT-PCR of SARS-CoV-2. COVID-19 is a respiratory infectious disease caused by SARS-CoV-2. Laboratory tests with ideal precision, sensitivity, and specificity should be used in public health and clinical settings. We analyzed analytical and clinical performance of the Roche and Abbott SARS-CoV-2 antibody assays in pre-pandemic and pandemic patient populations. Additionally, we analyzed the sensitivity of both assays in patients at different stages of the disease. The 2 assays showed similar analytical and clinical performance, but the Roche assay may be slightly more sensitive for patients tested within 0–6 days after first positive RT-PCR of SARS-CoV-2. Our findings help other clinical labs select appropriate assays for SARS-CoV-2 antibody testing.

scholarly journals kinetics of anti-SARS-CoV-2 antibodies over time. Results of 10 month follow up in over 300 seropositive Health Care Workers

2021 ◽  
Author(s):  
Jose Felipe Varona ◽  
Rodrigo Madurga ◽  
Francisco Peñalver ◽  
Elena Abarca ◽  
Cristina Almirall ◽  
...  
Keyword(s):  
Health Care ◽  
Health Care Workers ◽  
Care Workers ◽  
Kinetics Of ◽  
Over Time

scholarly journals COVID – 19 related knowledge and preventive practices early in the outbreak among health care workers in selected public health facilities of Illu aba Bor and Buno Bedelle zones, Southwest Ethiopia

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Dereje Tsegaye ◽  
Muluneh Shuremu ◽  
Dereje Oljira ◽  
Sileshi Dubale ◽  
Getachew Befekadu ◽  
...  
Keyword(s):  
Public Health ◽  
Health Care ◽  
Health Care Workers ◽  
Personal Protective Equipment ◽  
Infection Prevention ◽  
Health Facilities ◽  
Protective Equipment ◽  
Southwest Ethiopia ◽  
Preventive Practices ◽  
Care Workers

Abstract Background Novel-coronavirus 2019 (COVID-19) disease is currently a worldwide health risk and public health emergency concern. The virus is transmitted from an infected person to another person through close contact and droplets. Frontline health care workers are the most at risk of infection, and so a WHO interim guidance document was issued by the World Health Organization (WHO) which underscores the importance of proper sanitation and waste management practices for COVID- 19 in health-care settings. This study aimed at assessing knowledge and preventive practices towards Covid-19 among health care providers in selected health facilities of Illu Aba Bor and Buno Bedele zones, Southwest Ethiopia. Methods An institution-based cross-sectional study was conducted from April to May 2020 among 330 health workers in selected health facilities of Illu Aba Bor and Buno-Bedelle Zones, Southwest Ethiopia. Data were collected using a self-administered structured questionnaire. The collected data were entered into Epidata version 3.1 and exported to SPSS version 23 for analysis. Bivariate and multivariable logistic regression analysis was used to identify independent predictors of preventive practices towards Covid-19. Statistical significance was declared at a p-value of < 0.05. Result The majority of respondents (93.3%) demonstrated good knowledge of COVID-19, and the mean (SD) knowledge score was 9.04 ± 1.06. Nearly two-thirds (64.2%) of the study participants had good infection prevention practices. Being male (AOR = 3.65, 95% CI: (1.96, 6.80)), education level (AOR = 1.82, 95% CI (1.02, 3.22)), profession (AOR = 3.17, 95% CI (1.08, 9.33)), service year (5–10 years) (AOR = 2.00 (1.02, 3.92)) and more than 10 years (AOR = 3.14 (1.51, 6.52)), availability of personal protective equipment (AOR = 1.96 (1.06, 3.61)) and Knowledge level (AOR = 2.61 (1.48, 4.62)) were independent predictors of COVID-19 preventive practices. Conclusion The overall level of knowledge of HCWs was good. However, the practice was relatively low. Gender, educational status, profession, year of service, knowledge towards COVID-19, and availability of personal protective equipment were independent predictors of good infection prevention practices. Optimizing the infection prevention and control loop of the health facilities is recommended.

ANALYSIS OF THE ROLE OF THE ECONOMIST IN PUBLIC HEALTH

Vestnik ◽  
2021 ◽  
pp. 313-316
Author(s):  
И.Г. Турсумбай ◽  
Л.К. Кошербаева
Keyword(s):  
Public Health ◽  
Health Care ◽  
Comparative Analysis ◽  
Health Economics ◽  
Continuous Improvement ◽  
Health Care Workers ◽  
Economic Situation ◽  
Care Workers

Одним из последствий осуществления медицинской деятельности в разнообразных хозяйственных формах является изменение экономического положения работников здравоохранения. От количества и качества их труда зависит экономический результат деятельности лечебно-профилактических учреждений (ЛПУ) в целом. В статье приводится сравнительный анализ занимающихся подготовкой экономистов в области здравоохранения по различным критериям. Подчеркивается необходимость непрерывного совершенствования подготовки управленческих кадров в области экономики здравоохранения в современных условиях развития общества. One of the consequences of the implementation of medical activities in various economic forms is a change in the economic situation of health care workers. The number and quality of their work depends on the economic result of the activities of medical and preventive institutions (LPU) as a whole. The article presents a comparative analysis of the health economists who are engaged in training according to various criteria. The necessity of continuous improvement of training of managerial personnel in the field of health economics in the modern conditions of society development is emphasized.

Risking Lives to Save Others During COVID-19: A Focus on Public Health Care Workers in Bangladesh and Egypt

2021 ◽  
pp. 002073142110637
Author(s):  
Shahjahan Bhuiyan
Keyword(s):  
Public Health ◽  
Health Care ◽  
Health Care Workers ◽  
Health Workers ◽  
Public Health Care ◽  
Altruistic Behavior ◽  
Ongoing Research ◽  
Health Crisis ◽  
Street Level ◽  
Care Workers

The coronavirus (COVID-19) pandemic has been spreading around the world, causing a major public health crisis that has already claimed hundreds of thousands of lives. Street-level bureaucrats­—health workers, teachers, street cleaners, police officers­, and so forth—are at the forefront in fighting against the pandemic. Of these, public health care workers, due to the nature of their involvement, should know and understand why they are risking their lives to save others during this pandemic. Based on the preliminary data gleaned from interviews with public health care workers in Bangladesh and Egypt, this ongoing research suggests they are risking their lives for reasons such as altruistic behavior, service to profession, adherence to bureaucratic accountability, and a desire to help mankind. The findings contribute to the existing literature about street-level bureaucratic behavior in atypical times such as these of the pandemic. This study is unique in that it comprehends that public health care workers of two culturally and geographically distinct countries are risking their lives for the same public-spirited cause.

scholarly journals Epidemiology of ebolavirus disease (EVD) and occupational EVD in health care workers in Sub-Saharan Africa: Need for strengthened public health preparedness

2017 ◽  
Vol 27 (10) ◽  
pp. 455-461 ◽  
Author(s):  
Nlandu Roger Ngatu ◽  
Ntumba Jean-Marie Kayembe ◽  
Elayne Kornblatt Phillips ◽  
Joa Okech-Ojony ◽  
Masika Patou-Musumari ◽  
...  
Keyword(s):  
Public Health ◽  
Health Care ◽  
Health Care Workers ◽  
Sub Saharan Africa ◽  
Public Health Preparedness ◽  
Care Workers ◽  
Sub Saharan

Health Care Workers' Ability and Willingness to Report to Work During Public Health Emergencies

2011 ◽  
Vol 5 (4) ◽  
pp. 300-308 ◽  
Author(s):  
Andy Stergachis ◽  
Lisa Garberson ◽  
Onora Lien ◽  
Luann D'Ambrosio ◽  
Laura Sangaré ◽  
...  
Keyword(s):  
Public Health ◽  
Health Care ◽  
Health Care Workers ◽  
Influenza Pandemic ◽  
Public Health Emergencies ◽  
Work From Home ◽  
Care Workers ◽  
Viral Influenza ◽  
Willingness To Report ◽  
Ability And Willingness

ABSTRACTObjectives: We conducted a county-wide survey to assess the ability and willingness of health care workers to report to work during a pandemic influenza and a severe earthquake and to identify barriers and strategies that would help them report to work.Methods: A stratified random sample of 9211 health care workers was selected from the Washington state licensure database and from health care agencies. We assessed correlates between self-reported ability and willingness to report to work and demographic and employer-related variables under two scenarios, influenza pandemic and a severe earthquake.Results: For the influenza pandemic scenario, 95% of respondents reported that they would be able and 89% reported that they would be willing to report to their usual place of work. Seventy-four percent of respondents reported that they would be able and 88% would be willing to report to their usual place of work following a severe earthquake. The most frequently cited strategies that would help respondents report to work during an influenza pandemic were the availability of anti-viral influenza treatment and the ability to work from home. For persons with children at home, the strategy to increase ability to report to work during an earthquake was the availability of child care.Conclusions: The majority of the King County health care workforce is willing and able to respond to an influenza pandemic or a severe earthquake.(Disaster Med Public Health Preparedness. 2011;5:300–308)

scholarly journals Barriers in Adult Vitamin D Service Provision by Health Care Workers: a Qualitative Study in Three Ecologies of Ethiopia

2021 ◽  
Author(s):  
Wubegzier Mekonnen ◽  
Yeweyenhareg Feleke ◽  
Wubetsh Asnake ◽  
Jemal Haidar ◽  
Biruk Lambisso ◽  
...  
Keyword(s):  
Public Health ◽  
Health Care ◽  
Vitamin D ◽  
Qualitative Study ◽  
Vitamin D Deficiency ◽  
Health Care Workers ◽  
Public Health Problem ◽  
Health Facilities ◽  
Care Workers ◽  
Service Training

Abstract Background: Adult vitamin D deficiency, a public health problem in low-income countries, is correlated with increased mortality. Although health care workers (HCWs) in Ethiopia are educated on minerals counseling on the benefits of vitamin D and its sources is not witnessed since their knowledge is low. The main aim of this study is to explore barriers to good knowledge, positive attitude, and practice of health care providers on adult vitamin D.Methods: An exploratory qualitative study is done in three ecologies covering highland, midland, and lowland. The size of 27 participants was fixed by saturation of ideas. In-depth interviews were conducted among leaders and HCWs of different professional groups in health centers and hospitals. Moderators were Ph.D. holders. An interview guide was developed after reviewing research that was translated into the local language. Interviews were audio-taped, transcribed and, translated. Open Code software was used to code and categorize the data. Thematic analysis is presented using themes and sub-themes.Result: The main barriers are related to health systems, HCWs’ understandings, health facilities, and the educational system. Lack of attention by the health systems’ leadership, missing adult vitamin D as a priority in health programs, and the absence of adult vitamin D management and treatment guidelines are barriers related to the health system. On the other hand, health care professionals believed that the prevalence of adult vitamin D deficiency is insignificant and vitamin D deficiency is only an issue related to children. Besides, the inadequacy of laboratory investigation and limited in-service training are barriers related to health facilities while the absence of studies and the focus of the medical curriculum on child vitamin D are barriers related to the education system. Conclusion: Adult vitamin D deficiency is a neglected public health problem with many barriers related to diagnosis and treatment. Barriers are related to the professionals themselves, their leadership, health facilities, and the education system. The government should give attention to adult vitamin D management and treatment, continuous on the job training, development of guidelines, purchase of laboratory equipment, the inclusion of adult vitamin D in pre-service and, in-service training curriculums.

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