scholarly journals AB0933 PHYSICAL ACTIVITY DECREASES PAIN AND INFLAMMATION IN GOUT PATIENTS

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1766.1-1767
Author(s):  
N. Schlesinger ◽  
K. Jablonski ◽  
E. Schwarz ◽  
N. Young

Background:Despite the high prevalence of gout, there has been little investigation into the relationship between physical activity and gout.Objectives:To investigate whether physically active gout patients, as assessed by the International Physical Activity Questionnaire (IPAQ) long form, have lower pain scores, decreased inflammation, assessed by C-reactive protein (CRP) levels and less flares.Methods:During scheduled appointments, gout patients not experiencing a flare at the time of visit were recruited from our clinics and consented to participate in the study. IPAQ were completed. Clinical data collected during the visit included age, years since diagnosis, flares per year, perceived pain at the time of visit and in the past 4 weeks, and C-reactive protein (CRP) levels.Results:Thirty gout patients were recruited. Ages 31-86 (mean 61); duration of gout: one- 43 years (mean 9). IPAQ, separated gout patients into physically active (n=16) and physically inactive cohorts (n=14) (p<0.001. Physically active gout patients had over 12-fold fewer gout flares per year (p<0.01); 10-fold less CRP (p<0.01, a 4.6-fold decrease in perceived pain at the time of visit (p<0.01), and a 2.8-fold decrease in perceived pain over the past 4-week period (p<0.05).Conclusion:This is the first study using a validated physical activity tool, IPAQ, to assess physical activity in gout patients. In this study, physically active gout patients were found to have lower CRP levels, less flares per year, and decreased pain perception compared to those that are not physically active, highlighting, the importance of incorporating physical activity as a possible adjunct treatment option during intervals between flares.References:[1]Benatti FB, Pedersen BK. Exercise as an anti-inflammatory therapy for rheumatic diseases-myokine regulation. Nat Rev Rheumatol 2015;11:86-97.[2]Hagströmer M, Oja P, Sjöström M. The International Physical Activity Questionnaire (IPAQ): a study of concurrent and construct validity. Public Health Nutr 2006;9:755-62.[3]Young NA, Jablonski K, Sharma J, Thomas E, Snoad B, Hampton J, et al. Low and Moderate Intensity Exercise Suppresses Inflammatory Responses in an Acute Mouse Model of Gout and Suggests Therapeutic Efficacy [abstract]. Arthritis Rheumatol. 2017;69 (suppl 10).Disclosure of Interests:Naomi Schlesinger Grant/research support from: Pfizer, AMGEN, Consultant of: Novartis, Horizon Pharma, Selecta Biosciences, Olatec, IFM Therapeutics, Mallinckrodt Pharmaceuticals, Speakers bureau: Takeda, Horizon, Kyle jablonski: None declared, Emmy schwarz: None declared, Nicholas Young: None declared

2007 ◽  
Vol 10 (1) ◽  
pp. 59-64 ◽  
Author(s):  
Hazzaa M Al-Hazzaa

AbstractObjectivesTo describe the physical activity profile of Saudi adults living in Riyadh, using the International Physical Activity Questionnaire (IPAQ) short-version telephone format.MethodsPhysical activity was assessed using the official Arabic short form of IPAQ, intended for use in telephone interview. The instrument asks for times spent in walking, moderate- and vigorous-intensity physical activity of at least 10 min duration. The sample consisted of 1616 Saudis, between 15 and 78 years of age, living in Riyadh. Participants were drawn from a list of names in the telephone book using a simple random method. Telephone interviews were administered during the spring of 2003 by trained male interviewers.ResultsThe final sample size was 1064 Saudi males and females (response rate of 66%), with males comprising about 66% of the respondents. Over 43% of Saudis did not participate in any type of moderate-intensity physical activity lasting for at least 10 min. More than 72% of the sample did not engage in any type of vigorous-intensity physical activity lasting for at least 10 min. The proportion of Saudis who walked for 150 min or more per week was 33.3%. Females were engaged more in moderate physical activity than males, whereas males participated more in vigorous activity compared with females. Activity levels did not show significant relationships with education level or job hours per week. Based on the three activity categories established by IPAQ, 40.6% of Saudis were inactive, 34.3% were minimally active and 25.1% were physically active. Physical inactivity increased with advancing age.ConclusionThe data suggest that the prevalence of physical inactivity among Saudis adults is relatively high. Efforts are needed to encourage Saudis to be more physically active, with the goal of increasing the proportion of Saudis engaging in health-enhancing physical activity.


2021 ◽  
Vol 8 (1) ◽  
pp. 21
Author(s):  
Deny Yudi Fitranti ◽  
Bunga Syifarahmi ◽  
Martha Ardiaria ◽  
Nurmasari Widyastuti

<p>Proses penuaan mempengaruhi peningkatan distribusi lemak abdominal dengan indikator lingkar pinggang (LP) dan rasio lingkar pinggang panggul (RLPP). Penimbunan lemak abdominal menyebabkan disfungsi jaringan adiposa sehingga mempengaruhi biomarker proinflamasi yaitu kadar serum <em>high-sensitivity C-reactive Protein</em> (hs-CRP). Penelitian bertujuan untuk mengetahui hubungan LP dan RLPP dengan kadar hs-CRP lansia wanita. Rancangan penelitian <em>cross sectional</em> pada 53 subjek dipilih secara <em>consecutive sampling</em>. Antropometri yang diukur adalah LP dan RLPP. Pengukuran kadar serum hs-CRP dianalisis dengan metode <em>enyme-linked immunosorbent assay</em> (ELISA). Wawancara yang dilakukan yaitu data diri, asupan, aktivitas fisik, dan riwayat konsumsi obat. Data asupan diperoleh dengan metode <em>food recall</em> 3x24 jam. Aktivitas fisik diperoleh menggunakan <em>International Physical Activity Questionnaire</em> (IPAQ). Analisis data digunakan uji korelasi <em>Spearman</em>. Hasil penelitian menunjukkan bahwa persentase LP pada lansia wanita yang berisiko sebesar 90,6%, RLPP yang berisiko sebesar 98,1%, dan kadar hs-CRP tinggi sebesar 30,2%. Terdapat hubungan positif antara LP dengan kadar serum hs-CRP (r=0,417 ; p=0,002). Dalam penelitian ini RLPP, aktivitas fisik, asupan energi, karbohidrat, protein, lemak, serat, vitamin A, vitamin C, vitamin D,vitamin E, dan selenium tidak berkorelasi dengan kadar hs-CRP. Simpulan penelitian ini adalah LP berkorelasi positif dengan kadar serum hs-CRP, namun RLPP tidak berkorelasi dengan kadar serum hs-CRP</p>


Author(s):  
Levi Frehlich ◽  
Anita Blackstaffe ◽  
Gavin R. McCormack

There is a growing public health interest in the contributions of the built environment in enabling and supporting physical activity. However, few tools measuring neighbourhood-specific physical activity exist. This study assessed the reliability of an established physical activity tool (International Physical Activity Questionnaire: IPAQ) adapted to capture perceived neighbourhood-specific physical activity (N-IPAQ) administered via the internet and compared N-IPAQ outcomes to differences in neighbourhood Walk Score®. A sample of n = 261 adults completed an online questionnaire on two occasions at least seven days apart. Questionnaire items captured walking, cycling, moderate-intensity, and vigorous-intensity physical activity, undertaken inside the participant’s perceived neighbourhood in the past week. Intraclass correlations, Spearman’s rank correlation, and Cohen’s Kappa coefficients estimated item test-retest reliability. Regression estimated the associations between self-reported perceived neighbourhood-specific physical activity and Walk Score®. With the exception of moderate physical activity duration, participation and duration for all physical activities demonstrated moderate reliability. Transportation walking participation and duration was higher (p < 0.05) in more walkable neighbourhoods. The N-IPAQ administered online found differences in neighbourhoods that vary in their walkability. Future studies investigating built environments and self-reported physical activity may consider using the online version of the N-IPAQ.


2016 ◽  
Vol 49 (1) ◽  
pp. 9 ◽  
Author(s):  
Franco Noce ◽  
Henrique De Oliveira Castro ◽  
Tadeu Sartini Ferreira ◽  
James Guo ◽  
André Gustavo Pereira de Andrade ◽  
...  

A inatividade física tem sido descrita como um dos principais problemas de saúde pública do século XXI. Neste contexto, a atividade física desempenha um papel importante na redução da prevalência de sedentarismo, melhorando a qualidade de vida e a saúde mental dos indivíduos. Objetivo: Este estudo teve como objetivo analisar a influência de seis meses de atividade física (AF) na qualidade de vida (QV) e estados de humor (EH) de adultos jovens. Métodos: Uma amostra de 32 indivíduos completou uma bateria de questionários para avaliar o seu nível de atividade física, qualidade de vida e estados de humor. Eles foram separados em dois grupos: sedentários (n = 15) e fisicamente ativos (n = 17). O International Physical Activity Questionnaire (IPAQ) foi utilizado para avaliar os níveis de AF, o WHO Quality of Life-BREF (WHOQOL_Bref) para QV e a Escala Brasileira de Humor (BRAMS) para os EH. Foi realizada análise fatorial de variância com medidas repetidas e teste post-hoc de Tukey (p ≤ 0,05) para QV e análise inferencial para os EH. Resultados: Escores de QV foram significantemente maiores para o grupo fisicamente ativo nos domí- nios ambiental e social. Da mesma forma, EH apresentaram maiores escores na dimensão Vigor para o grupo fisicamente ativo depois de seis meses, sem contudo, atingir os níveis de significância estatística. Conclusões: Estes resultados sugerem que AF pode influenciar positivamente aspectos na qualidade de vida do indivíduo. Contudo, os dados não evidenciam uma influência significativa da AF nos estados de humor


Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Miguel Bravo ◽  
Tomás Romero ◽  
Camila X Romero ◽  
Elard Koch ◽  
Daniela Sandoval ◽  
...  

Background: There is consensus in the value of assessing and counseling hypertensive patients in reference to their physical activities (PA). The International Physical Activity Questionnaire (IPAQ) is a commonly used instrument to asses the energy expenditure (EE) through different domains of daily activity. Objectives: The main purpose of this study was to assess the relation of self-reported PA through the IPAQ and the aerobic capacity using oxygen consumption (VO 2 ) measured directly in hypertensive sedentary women. Methods: Cross-sectional study in a simple random sub-sample of 64 hypertensive women between 35 and 55 years old, without physical limitation or coronary event. PA was evaluated using the Spanish version of the IPAQ to assess the energy expenditure (EE) and PA intensity (moderate or vigorous) in different domains (work, transport, domestic, leisure). VO 2 peak was measured directly, breath to breath (Fitmate Pro®), at a submaximal (85% [85 of 100] maximal heart rate) exercise test with 25 watt/3 min load increments in a bicycle ergometer. Results: Mean age was 48.4±5.2 years. Measured peak VO 2 was 16.5±2.6 mL/Kg/min with a predicted VO 2 max of 23±3.7 mL/Kg/min, both corresponding to a sedentary level. The greater proportion of EE was observed in work and domestic domains in contrast to leisure activities that had the lowest. Over 50% (1 of 2) of the PA was done at moderate intensity. Peak VO 2 showed a direct correlation with total EE, work and domestic, and finally, with the cost in PA done at moderate intensity. Table. Relationship between self-reported PA (IPAQ) and direct measurements of VO 2 Domain or PA type IPAQ EE (MET-min/week) * EE(%) † Pearson's Correlation coefficient VO 2 peak (ml/Kg/min) p-value IPAQ total 3,613 (1,976 - 5,589) − 0.539 0.001 Work 358 (0 - 2,230) 25.4 0.577 0.001 Transport 396 (89 - 795) 15.5 −0.103 0.542 Domestic 1,465 (893 - 2,520) 47.1 0.385 0.018 Leisure 153 (0 - 664) 13.1 −0.011 0.950 Moderate 1,672 (978 - 3,275) 57.4 0.560 0.001 Vigorous 0 (0 - 1,216) 12.8 0.249 0.136 * Data expressed as median (percentiles 25 and 75) † Percentage of mean EE of the domain or PA type according to total EE. Conclusion: In sedentary hypertensive women self reported PA using IPAQ is predominantly related to domestic and work activities at moderate intensity. Work, and domestic EE or moderate intensity global PA correlated well with the peak VO 2 directly measured during a sub maximal exercise test. Thus, IPAQ appears as an adequate instrument to assess the EE of hypertensive patients and its impact on their aerobic capacity.


Author(s):  
Tom Deliens ◽  
Vickà Versele ◽  
Jasper Jehin ◽  
Eva D’Hondt ◽  
Yanni Verhavert ◽  
...  

This study validated the International Physical Activity Questionnaire (IPAQ) and the Context-specific Sedentary Behavior Questionnaire (CSBQ) against accelerometry among parents-to-be. Sex-differences in potential misreporting of physical activity (PA) and sedentary behavior (SB) were also investigated. Self-reported total PA (TPA), light-intensity PA (LPA), moderate-intensity PA (MPA), vigorous-intensity PA (VPA), moderate-to-vigorous-intensity PA (MVPA), and SB of 91 parents-to-be (41 men and 50 women) were compared with Actigraph data according to sex. Furthermore, the extent of misreporting was compared between sexes. Strong correlations for TPA and weak-to-moderate correlations for LPA, MPA, VPA, MVPA, and SB were observed. Participants underestimated TPA by 1068 min/week (=17.8 h/week; −50%), LPA by 1593 min/week (=26.6 h/week; −83%), and SB by 428 min/week (=7.1 h/week; −11%) and overestimated MPA by 384 min/week (=6.4 h/week; +176%) and MVPA by 525 min/week (=8.8 h/week; +224%). Males overreported VPA more than females in absolute minutes per week (238 min/week, i.e., 4.0 h/week vs. 62 min/week, i.e., 1.0 h/week), whereas, in relative terms, the opposite (+850% vs. +1033%) was true. The IPAQ and CSBQ can be used with caution to estimate TPA and SB among parents-to-be considering a strong correlation but low agreement for TPA and a weak-to-moderate correlation but acceptable agreement for SB. We disadvise using these self-reports to estimate PA on the distinct intensity levels.


Sign in / Sign up

Export Citation Format

Share Document