scholarly journals AB0747 MATERNAL AND FETAL OUTCOMES IN PREGNANT WOMEN WITH JUVENILE IDIOPATHIC ARTHRITIS: A SYSTEMATIC LITERATURE REVIEW

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1402.1-1402
Author(s):  
R. Pinheiro Torres ◽  
M. H. Fernandes Lourenco ◽  
A. Neto ◽  
F. Pimentel Dos Santos ◽  
I. Silva ◽  
...  

Background:Juvenile idiopathic arthritis (JIA), one of the most common chronic diseases in children, can be classified in seven different categories according to its onset presentation. Concerns about pregnancy outcomes play a secondary role in disease approach. However, recent data showed an increased risk of pre-term birth in women with JIA instead the small patient samples analysed.Objectives:In this review, our aim is to describe the current available knowledge on JIA adverse, maternal and fetal, outcomes.Methods:A systematic literature review was conducted since January of 2000 until December 2020, by searching the PubMed and Embase bibliographic databases. The search was limited to articles in English language, presenting a comparator group (healthy individuals or patients without known auto-immune rheumatic diseases) and at least one clinical outcome of interest. Two independent reviewers screened the titles and abstracts followed by a full-text review to assess papers regarding their eligibility.Results:Ten observational studies out of 1560 references, fulfilled the inclusion criteria, of which, 9 were retrospective and 1 prospective. A total of 6.214 women with JIA (with 6.811 pregnancies) and 18.659.513 healthy controls (with 21.339.194 pregnancies) were included in this review.Concerning maternal outcomes, delivery by caesarian section (CS) was more frequent among JIA women (in 4 out of 6 studies). Pre-eclampsia was referred in 3 out of 6 studies and a higher risk of vaginal bleeding and placenta previa in one additional study. No study found an increased risk for gestational diabetes or hypertension in pregnant women with JIA.Regarding fetal outcomes, 8 studies revealed significantly increased of pre-term birth (only in first births in one study) but one study didn’t show any increased risk. Two studies showed a higher risk of small gestational age (SGA) and in another 2, increased risk for low birth weight (LBW). No evidence of increased risk of major congenital malformations.Conclusion:This systematic review suggests an increased risk for pre-eclampsia, preterm birth, delivery by CS, SGA and LBW, among pregnant women with JIA. Conclusions should be carefully interpreted, giving the heterogeneity of studied populations regarding demography, disease type, disease activity, and prescribed medication.Disclosure of Interests:None declared

2019 ◽  
Vol 38 (1) ◽  
pp. 113-137
Author(s):  
Tsvetanka Georgieva-Trifonova ◽  
Kaloyan Zdravkov ◽  
Donika Valcheva

Purpose The purpose of this paper is to summarize the current state of the existing research on the application of semantic technologies in bibliographic databases by providing answers to a set of research questions resulting from a systematic literature review. Design/methodology/approach The present study consists of conducting a systematic literature review of research works related to the application of semantic technologies in bibliographic databases. A manual keyword search is performed in known academic databases. As a result, a total of 78 literature sources are identified as related to the topic and included in the review. From the selected literature sources, information is extracted, which is then summarized and analyzed according to previously defined research questions and finally reported. Besides, a framework is defined to classify literature sources found and collected as a result of the study. The main criteria, according to which the classification is performed, are the used semantic technology and the research problem for which semantic technologies are applied in bibliographic databases. The classification of the publications is verified by each author independently of others. Findings The conducted systematic scientific review establishes that the evolution of semantic technologies sets a period of increased interest in the researchers, as a result of which the advantages of using them for bibliographic descriptions are examined and practically confirmed. After defining semantic models for bibliographic descriptions and approaches to transform existing bibliographic data into their correspondence, the research interest is directed at their comparison, collation; enrichment to facilitate search and retrieval of useful information. Possible perspectives for future research are outlined, which mainly relate to the complete use of the created data sets and their transformation into knowledge repositories. Originality/value Despite the increasing importance of the semantic technologies in various areas, including the bibliographic databases, there is a lack of comprehensive literature review and classification of literature sources relevant to this topic. The detailed study proposed in the present paper supports introducing with the existing experience in the application of semantic technologies in bibliographic databases, as well as facilitates the discovery of trends and guidelines for future research.


2021 ◽  
pp. 496-507
Author(s):  
Rifki S. Nompo ◽  
Andria Pragholapati ◽  
Angela L. Thome

Anxiety is a feeling of helplessness, and worry about things that are not clear, as well as a comprehensive feeling that something bad is going to happen. Anxiety is experienced subjectively and communicated interpersonally, at the same time feelings of anxiety are a necessary survival instinct. The Neuro-Linguistic Programming (NLP) is a communicative approach employs a positive view of anxiety and how it can help shape life changes, and that is the topic of this article. This research method uses a Systematic Literature Review, investigating Garuda, Pubmed, ScienceDirect, and Proquest, using boolean for keyword neurolinguistics programming (NLP) and anxiety. The inclusion criteria used were Indonesian and English language articles written within the last 5 years (from 2015 until 2020). The exclusion criteria used by the article were abstract writing style, inaccessible, or lacking national accreditation. Articles were tested with Critical Appraisal Tools. The studies indicate that good communication using NLP can help reduce anxiety and can promote changes in a person’s behavior patterns. There are several NLP techniques including sensory acuity, reframing, anchoring, rapport, and pacing, and leading. NLP can improve knowledge, skills and attitudes, communication skills, self-management, mental health, reduce work stress, and self-efficacy.   Keywords: Anxiety, Neuro-Linguistic Programming, NLP


2018 ◽  
Vol 29 (5) ◽  
pp. 768-788 ◽  
Author(s):  
Narpat Ram Sangwa ◽  
Kuldip Singh Sangwan

Purpose The purpose of this paper is to review various themes of leanness, leanness assessment approaches, leanness assessment areas, and their evolution by a systematic literature review (SLR). Design/methodology/approach The eight types of literature review methodologies are identified and compared. The SLR is selected after critically analyzing the eight types of literature reviews. A four-phased SLR (i.e. plan, do, analyze/synthesize, and propose) has been carried out based on the peer-reviewed journal and conference articles on leanness assessment. Findings The existing literature on leanness assessment shows the lack of review-based papers on lean assessment. This study attempts to build a two-fold contribution to the field of leanness assessment: first, various types of themes, approaches, and assessment areas are identified; second, a framework for leanness assessment is proposed. The study shows that the research on leanness assessment is mainly empirical using qualitative judgment. The paper traces the changes in scope, areas, and approaches to leanness assessment. The scope of leanness assessment broadened from manufacturing process assessment to whole supply chain assessment including manufacturing process. The focus of earlier assessment was manufacturing and financial areas which now includes human resource, administration, new product development, suppliers, and customers also. Tool and technique based assessment has given way to outcome-based assessment using non-financial and qualitative parameters. Research limitations/implications One of the limitations of the study is that literature search was mainly focused on peer-reviewed articles published in English language only; therefore, some papers in others languages may have been missed. Apart from this, the SLR has been conducted for the manufacturing sector only. Practical implications The study is expected to be useful for the lean practitioners to identify the causes of reported lean failures. Moreover, the authors also expect that the conducted SLR will provide the passage to the practitioners for not only fostering the concepts on leanness assessment but also provide the vital and significant knowledge about the leanness assessment to the managers for enhancing organizational performance. Originality/value As per the authors’ knowledge, this is the first SLR on leanness assessment. It is expected that this paper will help the researchers working in the area of lean manufacturing to identify new areas of research.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Madeleine Benton ◽  
Amy Salter ◽  
Nicole Tape ◽  
Chris Wilkinson ◽  
Deborah Turnbull

Abstract Background Given the sudden and unexpected nature of an emergency caesarean section (EmCS) coupled with an increased risk of psychological distress, it is particularly important to understand the psychosocial outcomes for women. The aim of this systematic literature review was to identify, collate and examine the evidence surrounding women’s psychosocial outcomes of EmCS worldwide. Methods The electronic databases of EMBASE, PubMed, Scopus, and PsycINFO were searched between November 2017 and March 2018. To ensure articles were reflective of original and recently published research, the search criteria included peer-reviewed research articles published within the last 20 years (1998 to 2018). All study designs were included if they incorporated an examination of women’s psychosocial outcomes after EmCS. Due to inherent heterogeneity of study data, extraction and synthesis of both qualitative and quantitative data pertaining to key psychosocial outcomes were organised into coherent themes and analysis was attempted. Results In total 17,189 articles were identified. Of these, 208 full text articles were assessed for eligibility. One hundred forty-nine articles were further excluded, resulting in the inclusion of 66 articles in the current systematic literature review. While meta-analyses were not possible due to the nature of the heterogeneity, key psychosocial outcomes identified that were negatively impacted by EmCS included post-traumatic stress, health-related quality of life, experiences, infant-feeding, satisfaction, and self-esteem. Post-traumatic stress was one of the most commonly examined psychosocial outcomes, with a strong consensus that EmCS contributes to both symptoms and diagnosis. Conclusions EmCS was found to negatively impact several psychosocial outcomes for women in particular post-traumatic stress. While investment in technologies and clinical practice to minimise the number of EmCSs is crucial, further investigations are needed to develop effective strategies to prepare and support women who experience this type of birth.


2020 ◽  
Vol 17 ◽  
pp. 147997311990123 ◽  
Author(s):  
Maryam Navaie ◽  
Carole Dembek ◽  
Soojin Cho-Reyes ◽  
Karen Yeh ◽  
Bartolome R Celli

Inhaled bronchodilators are the cornerstone of treatment for chronic obstructive pulmonary disease (COPD). Soft mist inhalers (SMIs) are devices that deliver bronchodilators. Although correct device use is paramount to successful medication delivery, patient errors are common. This global systematic literature review and meta-analysis examined device use errors with SMIs among patients with obstructive lung diseases. PubMed, EMBASE, PsycINFO, Cochrane, and Google Scholar were searched to identify studies published between 2010 and 2019 that met the following inclusion criteria: (a) English language; (b) a diagnosis of COPD, bronchitis, or emphysema; and (c) reported device use errors among adults receiving long-acting bronchodilator treatment with Respimat® SMI (i.e. Spiriva®, Stiolto®, Spiolto®, and Striverdi®). Descriptive statistics examined sociodemographics, clinical characteristics, and device use errors. Meta-analysis techniques were employed with random-effects models to generate pooled mean effect sizes and 95% confidence intervals (CIs) for overall and step-by-step errors. The I 2 statistic measured heterogeneity. Twelve studies ( n = 1288 patients) were included in this meta-analysis. Eighty-eight percent of patients had COPD, and most had moderate/very severe airflow limitation (Global Initiative for Chronic Obstructive Lung Disease spirometric stages II to IV). Aggregate results revealed that 58.9% (95% CI: 42.4–75.5; I 2 = 92.8%) of patients made ≥1 device use errors. Among 11 studies with step-by-step data, the most common errors were failure to (1) exhale completely and away from the device (47.8% (95% CI: 33.6–62.0)); (2) hold breath for up to 10 seconds (30.6% (95% CI: 17.5–43.7)); (3) take a slow, deep breath while pressing the dose release button (27.9% (95% CI: 14.5–41.2)); (4) hold the inhaler upright (22.6% (95% CI: 6.2–39.0)); and (5) turn the base toward the arrows until it clicked (17.6% (95% CI: 3.0–32.2)). Device use errors occurred in about 6 of 10 patients who used SMIs. An individualized approach to inhalation device selection and ongoing training and monitoring of device use are important in optimizing bronchodilator treatment.


2018 ◽  
Vol 7 (3) ◽  
pp. 217-229 ◽  
Author(s):  
Sarah Seleznyov

Purpose The purpose of this paper is to explore the popularity of Japanese lesson study (JLS) beyond Japan and the challenges this translation might pose. It notes that there is not a universally accepted definition of lesson study (LS) and seeks to identify the “critical components” of JLS through a review of the literature. It then uses a systematic literature review of recent studies of the implementation of LS with in-service teachers beyond Japan to analyse the models of LS used against these seven critical components in order to explore the degree of fidelity to the Japanese model. Design/methodology/approach A broad review of the literature on JLS available in the English language identifies seven “critical components”. A systematic literature review of 200 recent English language studies of the implementation of LS with in-service teachers beyond Japan is then carried out. Articles published between 2005 and 2015 are explored, including peer reviewed articles, scientific journals, book chapters and PhD dissertations. This systematic review enables an analysis of the models of LS used in studies from beyond Japan against the “seven critical components” of JLS. Findings The analysis shows that there is not an internationally shared understanding of Japanese lesson study (JLS) and that many of the missing components are those which distinguish LS as a research process, not simply a collaborative professional development approach. It also reveals that UK LS models seem particularly far from the Japanese model in those critical components which connect teachers’ knowledge and understanding within groups, to knowledge and understanding that exists beyond it. The study discusses whether these differences could be attributed to structural or cultural differences between Japan and other nations. Research limitations/implications The search for descriptions of the JLS is limited to articles available in the English language, which, therefore, represent a quite limited body of authority on the “critical components” of LS. The systematic review is similarly limited to English language articles, and there is a clear bias towards the USA, with the Far East and the UK making up the majority of the remaining studies. The study suggests that future research on LS beyond Japan should consider teachers’ attitudes towards the research elements of the process as well as their skills and confidence in carrying out research into practice. Practical implications The study strikes a note of caution for schools wishing to implement JLS as an approach to teacher professional development in the UK and beyond. Japan’s systemic approach has embedded LS experience and expertise into the education system, meaning a uniform approach to LS is much more likely. In addition, other systemic challenges may arise, for example, UK professional development time and resources is not designed with JLS in mind and may therefore require a significant reworking. Originality/value Whilst several systematic reviews of LS have explored its growth, geographical spread, impact and key features, this study provides a different perspective. It analyses whether and to what degree the “lesson study” models these studies describe align with the literature on JLS, and the implications of this for researchers and practitioners.


2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S90-S90
Author(s):  
Eloise Williams ◽  
Adam W Jenney ◽  
Denis W Spelman

Abstract Background Nocardia bacteremia is a rare but important phenomenon, with previous studies describing a 50% mortality rate. We undertake a single-center review and the largest systematic review of Nocardia bacteremia performed over the past 20 years. Methods A single-center review of cases of Nocardia bacteremia was performed using hospital microbiology records from January 1, 2010 to December 31, 2017. A systematic literature review was also performed to identify cases of Nocardia bacteremia described in the English language literature between January 1, 1999 and December 31, 2018 using the NCBI PubMed database and snowballing from citations of relevant publications. Results Single-center case series: Four cases of Nocardia bacteremia are described. Three patients had an intravascular device in situ prior to the onset of Nocardia bacteremia and three patients were immunocompromised; one patient had both risk factors. Systematic literature review: A systematic review identified 50 publications that described 85 cases with sufficient patient data to be reviewed in detail. Including the 4 cases described in our institution, 89 cases of Nocardia bacteremia were included in the analysis. The median age was 57 years [interquartile range (IQR) 42–68] and 69% were male. Eighty-two percent of cases were immunocompromised and 38% had endovascular devices. Pulmonary infection was the most common concurrent site of clinical disease (66%), followed by central nervous system (25%), pleural (17%) disease, and endocarditis (11%). Blood cultures were the only positive microbiological specimen that isolated Nocardia in 45% of cases. Median incubation time to blood culture positivity was 4 days [IQR 3–6]. Thirty-day all-cause mortality was 24% and overall all-cause mortality was 42%. Conclusion Four new cases of Nocardia bacteremia are described. Isolation of Nocardia from blood cultures is rare but represents serious infection with high associated overall mortality. Nocardia bacteremia is most frequently identified in immunocompromised patients and those with intravascular devices. Disclosures All authors: No reported disclosures.


Rheumatology ◽  
2020 ◽  
Author(s):  
Amihood Singer ◽  
Julia Grinshpun-Cohen ◽  
Lena Sagi-Dain

Abstract Objectives To examine the risk for chromosomal aberrations in fetuses of colchicine-treated patients in a large cohort, and to perform a systematic literature review on the subject. Methods For the observational study, a retrospective search was performed through the Ministry of Health computerized database, for all invasive tests performed due to parental colchicine treatment over the years 2003–19. The rate of aberrant karyotypes in pregnancies exposed to colchicine was compared with a local cohort of 2752 normal pregnancies, yielding six (0.2%) karyotype-detectable findings. In addition, a systematic literature search was conducted for studies examining the rate of chromosomal aberrations in pregnancies exposed to colchicine. Results The study group consisted of 755 pregnancies karyotyped due to colchicine exposure. A marked decrease due to this indication was noted over the years (i.e. 67 cases in 2003 vs 8 in 2019). Five (0.66%) chromosomal aberrations were noted: 47,XXY; 45,X0; 47,XYY; and two fetuses with trisomy 21. This rate was significantly increased compared with the control population [relative risk 2.2 (95% CI: 1.1, 4.2)]. Literature search yielded four studies encompassing 740 pregnancies. The rate of chromosomal aberrations ranged from ‘none’ (in three studies) up to 1.5%. Quality assessment of the evidence was defined as ‘low’. Conclusion The results of our observational study support the concern that colchicine treatment is associated with increased risk for fetal chromosomal aberrations; however, the absolute risk is relatively low (one in 151 pregnancies). This information should be taken into account when considering invasive testing in such pregnancies.


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