scholarly journals Knowledge of and attitudes toward clinical trials in Saudi Arabia: a cross-sectional study

BMJ Open ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. e031305 ◽  
Author(s):  
Nedal Al-Rawashdeh ◽  
Rana Damsees ◽  
Majed Al-Jeraisy ◽  
Eman Al Qasim ◽  
Ahmad M Deeb
Keyword(s):  
Clinical Trials ◽  
Saudi Arabia ◽  
Educational Level ◽  
Drug Testing ◽  
Knowledge Score ◽  
New Drugs ◽  
Secondary Outcome ◽  
Cross Sectional ◽  
Medical Background ◽  
Level Of Knowledge

ObjectivesClinical trials (CTs) are considered an important method for developing new treatments and providing access to potentially effective drugs that are still under investigation. Measuring the public’s knowledge of and attitudes toward CTs is important for assessing their readiness for and acceptance of human drug testing, which has previously not been assessed in the Kingdom of Saudi Arabia (KSA). The objective of this study is to explore the Saudi public’s knowledge of and attitudes toward CTs as well as participation in trials to test new or approved drugs.DesignCross-sectional.SettingThe 2016 Al Jenadriyah cultural/heritage festival in Riyadh, KSA.ParticipantsParticipating booths and exhibition halls, as well as festival visitors, were approached to participate in the study.Primary and secondary outcome measuresKnowledge of and attitudes toward CTs.ResultsThe final number of participants was 938. The responses were converted to a percentage mean score (out of 100) for each knowledge-related response and attitude. The total mean knowledge score was 56.8±24.8 and the attitude-related score was 61.5±28.0. Although most of the participants supported testing approved or off-label and new drugs on adult and paediatric patients, only a third (30.5%) agreed that new drugs could be tested on healthy volunteers. The results indicated that gender, educational level, income, medical background, age and health insurance were independently associated with the level of knowledge of CTs. In terms of attitudes toward CTs, the factors that were independently associated were gender, educational level and medical background.ConclusionsThe Saudi public has a low level of knowledge and a moderately positive attitude toward CTs. There is a moderate positive correlation between the two factors such that as knowledge of CTs increases, the Saudi public will hold more positive attitudes toward CTs.

scholarly journals Knowledge, Attitude and Awareness towards Corneal Donation in Aseer Region, Saudi Arabia

2021 ◽  
Vol 20 (11) ◽  
Author(s):  
Abdulrahman Mohammed Al-Amri ◽  
Faisal Misfer Alqahtani ◽  
Hassan Abdullah Alqahtani ◽  
Mansour Salem Alqahtani ◽  
Mohammed Moshabbab Alqahtani ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Corneal Transplantation ◽  
Knowledge Score ◽  
Corneal Dystrophy ◽  
Cross Sectional ◽  
Factors Affecting ◽  
Corneal Transplants ◽  
Level Of Knowledge ◽  
Corneal Donation ◽  
Sight Restoration

Background: Corneal transplantation is the mainstay procedure performed for sight restoration in patients with corneal blindness, which can be caused by infection, corneal dystrophy, degenerative disorders such as keratoconus or traumatic causes. Most corneal transplants in Saudi Arabia are performed using imported corneas. Aims: To determine the level of knowledge and awareness and the factors affecting corneal donation in Aseer region, Saudi Arabia. Subjects and Methods: A descriptive cross-sectional approach was used targeting the population of Aseer region aged 18 years and above. The data were collected using electronic self-administered questionnaire. The tool covered the participants’ biodemographic data, knowledge related questions and willingness of corneal donation and factors affecting such attitudes. Results: Of the 641 participants, 66.1% were males, 47.6% were in the age group 20 – 30 years and 19.2% claimed to have enough knowledge about corneal donation. The mean knowledge score (SD) was 2.13 (1.757) out of 8. Regarding participants’ attitude, 26.7% were willing to donate their own cornea. The willingness was significantly associated with good level of knowledge (p = 0.008). Females were more inclined to donate their corneas than males (30.9% vs 24.5%, p = 0.025). Conclusion: The study revealed a low level of knowledge of corneal donation in Aseer region, Saudi Arabia. Approximately one quarter of the participants reported willingness of corneal donation. Lack of knowledge was the main barrier, as it was reported by almost two thirds. Key words: Cornea, Donation, Awareness, Penetrating Keratoplasty, Saudi Arabia

scholarly journals A Questionnaire-Based Survey to Assess the Level of Knowledge and Awareness about Drug–Food Interactions among General Public in Western Saudi Arabia

Pharmacy ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 76
Author(s):  
Syed Faisal Zaidi ◽  
Rayan Mgarry ◽  
Abdullah Alsanea ◽  
Sakar Khalid Almutairi ◽  
Yaser Alsinnari ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Statistical Significance ◽  
Cross Sectional Study ◽  
Exclusion Criteria ◽  
Cross Sectional ◽  
Jeddah City ◽  
Fundamental Information ◽  
Inadequate Knowledge ◽  
Level Of Knowledge ◽  
Males And Females

Introduction: Various drug–food interactions exist that may hinder treatment and can sometimes be lethal. Our aim was to assess the level of public knowledge and awareness in Jeddah city, Western Saudi Arabia, about drug–food interactions, along with the effects of demographics on their knowledge. Methods: A survey questionnaire was administered in this cross-sectional study to participants spread across multiple locations in Jeddah, including in malls and public gatherings. Participants included both males and females. Sample size was calculated through Raosoft® software. Data analysis was executed using IBM Statistic SPSS and the level of statistical significance was set at p < 0.05. Results: A total of 410 people participated in the study and only 92.68% (380) of responses were enrolled in the study; 7.32% (30) were not enrolled due to the exclusion criteria. Surprisingly, only six out of eighteen questions regarding drug–food interactions in the administered questionnaire were correctly answered by 380 participants. Data indicated that the participants had a poor to intermediate level of both knowledge and awareness with respect to drug–food interactions. Furthermore, participants showed moderate to strong awareness of the effects of alcohol and tea generally, and their interaction with medication. Conclusion: Participants in our study showed inadequate knowledge of basic and fundamental information about drug–food interactions, which highlights the dire need to increase awareness.

scholarly journals Knowledge and understanding of obstetric danger signs among pregnant women attending the antenatal clinic at the National Referral Hospital in Thimphu, Bhutan: a cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Saran Tenzin Tamang ◽  
Thinley Dorji ◽  
Sonam Yoezer ◽  
Thinley Phuntsho ◽  
Phurb Dorji
Keyword(s):  
Pregnant Women ◽  
Knowledge Score ◽  
Antenatal Clinic ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Obstetric Danger Signs ◽  
Danger Signs ◽  
Obstetric Emergencies ◽  
Level Of Knowledge

Abstract Background The third Sustainable Development Goal for 2030 development agenda aims to reduce maternal and newborn deaths. Pregnant women’s understanding of danger signs is an important factor in seeking timely care during emergencies. We assessed knowledge of obstetric danger signs using both recall and understanding of appropriate action required during obstetric emergencies. Methods This was a cross-sectional study among pregnant women attending antenatal clinic at Bhutan’s largest hospital in Thimphu. Recall was assessed against seven obstetric danger signs outlined in the Mother and Child Health Handbook (7 points). Understanding of danger signs was tested using 13 multiple choice questions (13 points). Knowledge was scored out of 20 points and reported as ‘good’ (≥80%), ‘satisfactory’ (60–79%) and ‘poor’ (< 60%). Correlation between participant characteristics and knowledge score as well as number of danger signs recalled was tested using Pearson’s correlation coefficient. Association between knowledge score and participant characteristics was tested using t-tests (and Kruskal-Wallis test) for numeric variables. Socio-demographic and clinical characteristics associated with the level of knowledge ('good’ versus ‘satisfactory’ and ‘poor’ combined) were assessed with odds ratios using a log-binomial regression model. All results with p < 0.05 were considered significant. Results Four hundred and twenty-two women responded to the survey (response rate = 96.0%). Mean (±SD) knowledge score was 12 (±2.5). Twenty women (4.7%) had ‘good’ knowledge, 245 (58.1%) had ‘satisfactory’ knowledge and 157 (37.2%) had ‘poor’ knowledge. The median number of danger signs recalled was 2 (IQR 1, 3) while 68 women (20.3%) could not recall any danger signs. Most women were knowledgeable about pre-labour rupture of membranes (96.0%) while very few women were knowledgeable about spotting during pregnancy (19.9%). Both knowledge score and number of danger signs recalled had significant correlation with the period of gestation. Women with previous surgery on the reproductive tract had higher odds of having ‘good’ level of knowledge. Conclusions Most pregnant women had ‘satisfactory’ knowledge score with poor explicit recall of danger signs. However, women recognized obstetric emergencies and identified the appropriate action warranted.

scholarly journals Knowledge on postnatal care among postpartum mothers during discharge in maternity hospitals in Asmara: a cross-sectional study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Ghirmay Ghebreigziabher Beraki ◽  
Eyasu H. Tesfamariam ◽  
Amanuel Gebremichael ◽  
Berhanemeskel Yohannes ◽  
Kessete Haile ◽  
...  
Keyword(s):  
Breast Feeding ◽  
Educational Level ◽  
Postnatal Care ◽  
Knowledge Score ◽  
Cross Sectional Study ◽  
Postnatal Period ◽  
Danger Sign ◽  
Cross Sectional ◽  
Maternity Hospitals ◽  
Postpartum Mothers

Abstract Background The early postnatal period is a dangerous time for both mother and baby where morbidity and mortality are highly prevalent if proper care is not done. Post natal care (PNC) knowledge has significant role in reducing such complications. In this study, the knowledge of postpartum mothers on PNC and its determinants were determined. Methods A cross-sectional quantitative study was conducted in postpartum mothers (PpM) who attended all maternal delivery services in Asmara. Data was collected by a structured questionnaire. All (n = 250) PpM who gave birth in December, 2017 were included in the study. Independent samples t-test and one way ANOVA were used to compare the scores in knowledge across categories of background characteristics using SPSS. Bonferroni post-hoc test was performed for variables that were found to be significant while using ANOVA tool. P-values less than 0.05 were considered as significant. Results The percentage of PpM who cited vaginal bleeding, as a maternal danger sign, and fever, as a baby danger sign, were 83.2 and 58.8%, respectively. The majority (96%) of PpM responded the correct answer on where to go if they note any danger signs. In addition, more than nine tenth of PpM correctly identified injectable contraceptives (92.7%) and oral contraceptive (91.5%). The percentages of knowledge in recognizing the necessary nutrients ranged from 87.6% for carbohydrates to 46% for minerals. The percentages of correct knowledge regarding first baby bath, frequency of breast feeding, umbilical care, duration of exclusive breast feeding, need and purpose of vaccine were 40.1, 81.9, 77.4, 94.8, and 99.2% respectively. The mean PNC knowledge score was 24.89/60. The score of knowledge on postnatal care was found to significantly differ across the categories of residence (p < 0.001) and ethnicity (p = 0.015). An increasing trend of knowledge score was observed with increase in age group (p < 0.001), educational level (p = 0.021), gravida (p < 0.001) and para (p < 0.001). Conclusion Considerable gaps in knowledge regarding postnatal care among postpartum mothers were evident. Special attention should be laid on rural residents, single/living together, junior/below in educational level, primigravida/para, non-Tigrigna ethnicity, and 17 to 25 years old mothers.

Parental Perception of the Role of Color Additives in Food on Children's Behavior in Jazan Region of Saudi Arabia

2020 ◽  
Vol 19 (3) ◽  
pp. 308-311
Author(s):  
Hafiz A. Makeen ◽  
Saad S. Alqahtani ◽  
Nawazish Alam ◽  
Santhosh J. Menachery ◽  
Rabea M. Ageeli ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Harmful Effect ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Children's Behavior ◽  
Food And Beverages ◽  
Validated Questionnaire ◽  
Level Of Knowledge ◽  
Coloring Agents ◽  
Artificial Food Colors

Natural and artificial food colors are widely used in a variety of food products. This study was designed to assess the awareness and perception of coloring agents present in food and beverages on children's behavior among people of Jazan, Saudi Arabia. A cross-sectional study was conducted on representative samples of 387 married people from different places in Jazan region of Saudi Arabia from August to December 2019. The study utilized a validated questionnaire consisting of 12 questions to gather the information from 387 participants (52.9% males and 47.03% females). Approximately 77% were young adults; belong to age group of 26-45 years (P = 0.000). Majority (40.5%) of them had four or more children (P = 0.000). While significant level of knowledge about the use of foods and beverages containing coloring agent was found in the participants (P = 0.001), they were not aware that it may affect the child's health. Only 24.7% were able to tell the name of a coloring agent (P = 0.001). Significant percentage (88.9%) of parents reported about child hyperactivity after consumption of specific type of food and beverages, particularly fizzy drinks (35.61%), chocolates (31.82%), and sweets and candy (30.3%). Target populations were considered to be aware of presence of coloring agent in food and beverages used by their children regularly but they are not much aware of its harmful effect on long-term use.

scholarly journals Awareness and Opinions of Research Professionals on India's New Drug and Clinical Trials Regulations: Protocol for a Cross-Sectional Web-Based Survey Study

10.2196/14744 ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. e14744
Author(s):  
Vishal Vennu ◽  
Saurabh Dahiya
Keyword(s):  
Clinical Trial ◽  
Clinical Trials ◽  
New Drugs ◽  
Survey Study ◽  
Multiple Sources ◽  
Cross Sectional ◽  
Web Based ◽  
Google Docs ◽  
New Drug ◽  
Research Professionals

Background Although several studies have been conducted and several articles have been published on India's new clinical trial regulations, very few have examined the views of investigators and ethics board members regarding modifications to the previous regulations. Overall, they have neglected to find out the opinions of other relevant professionals, such as research assistants, coordinators, associates, and managers. To our knowledge, no study has yet investigated the awareness and opinions of Indian research professionals on the new 2019 regulations. Objective This study aims to describe the awareness and opinions of Indian research professionals on the new drug and clinical trial regulations. Methods In this cross-sectional, Web-based study, we will conduct an open survey for various Indian research professionals. These professionals will be selected randomly using multiple sources. The survey questionnaires, which have already been validated, were developed using the form function in Google docs. A Web link was generated for participants to take the survey. Descriptive statistics will be shown as means and standard deviations for constant variables, whereas certain variables will instead be shown as numbers and percentages. Results The survey was opened in July 2019. Enrollment has already started and will be completed in three months. The results calculations are expected to begin in October 2019. Conclusions The results of the survey are expected to represent the views of research professionals on the new regulations that will support the development of clinical research and the pharmaceutical industry in India. These regulations are expected to help advance clinical trials, help with the approval of new drugs, and enhance ethical norms in the country. International Registered Report Identifier (IRRID) PRR1-10.2196/14744

scholarly journals Knowledge and Belief towards Infertility among Undergraduate Students of Selected Colleges of Pokhara Metropolitan City

2019 ◽  
Vol 9 (2) ◽  
pp. 24-28
Author(s):  
Alisha Dhungana ◽  
Kalpana Jnawali
Keyword(s):  
Undergraduate Students ◽  
Public Health Problem ◽  
Knowledge Score ◽  
Female Students ◽  
World Health ◽  
Global Public Health ◽  
Cross Sectional ◽  
Metropolitan City ◽  
Good Level ◽  
Level Of Knowledge

Introduction: Infertility is the global public health problem with adverse social and economic consequences. World Health Organization states that infertility affects 1 in every 10 couples worldwide. This study was carried out with an objective to find out the level of knowledge and belief regarding infertility among undergraduate students. Methods: This was a cross-sectional and quantitative study, carried out among 420 undergraduate students of 7 selected colleges of Pokhara Metropolitan city from July to September 2019. Study populations were selected through simple random sampling method. Data collection was carried out using self-administered questionnaire. Results: Study revealed that 51.9% students had good level of knowledge with the female students having greater knowledge (57%) than male (48%). The study found that students’ knowledge score related to infertility was significantly associated with gender (p<0.05) and parental advices (p<0.05). Conclusions: More than half of the participants had good level of knowledge. Female students were more knowledgeable than male students. Less than half of the participants had ever attended on sexual and reproductive training programs.

scholarly journals Knowledge, attitude, and practices towards COVID-19: a cross-sectional study among nursing and midwifery students in Jalingo, Nigeria

2021 ◽  
Vol 8 (3) ◽  
pp. 1122
Author(s):  
Hope Inegbenosun ◽  
Clement Chinedu Azodo ◽  
John Chukudi Anionye ◽  
Collins Usunobun Inegbenosun ◽  
Obinna Chukwunwike Njoku
Keyword(s):  
Health Workers ◽  
Knowledge Score ◽  
Educational Interventions ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Running Water ◽  
Preventive Practices ◽  
Positive Attitudes ◽  
Level Of Knowledge

Background: The coronavirus disease (COVID-19) infection rate and mortality among Nigerian health care workers appear to be on the increase. Aside from health workers, it has caused millions of infections and deaths worldwide.  This study determined the level of knowledge, attitude, and practices of nursing and midwifery students towards COVID-19 in a North-Eastern Nigerian state.Methods: A total of 156 respondents were involved in this institutional-based cross-sectional study, conducted after the lockdown period. A total of 17 questions were used to assess the KAP with knowledge appraised with 12 questions, attitudes with 2 questions, and practices with 3 questions.Results: The majority of the students (53.80%) possessed a good level of knowledge regarding COVID-19, while 40.4% had fair knowledge regarding COVID-19 with only 5.80% having poor knowledge of COVID-19. The mean knowledge of COVID-19 in this study was 9.40±1.353 with an overall 78% correct answer rate. A vast majority of the respondent (82.7% and 98.1%) had strong confidence in Nigeria and believed that the pandemic will soon be over, respectively. Only a few avoided large gatherings of people (30.8%) with the vast majority reporting to have worn a mask when going out (84.6%) and washing their hands with running water and soap frequently as recommended (73.1%). In multiple logistic regression analyses, the COVID-19 knowledge score (OR: 0.39-0.40, 95%CI: 0.26 – 0.62, P<0.05) was significantly associated with a lower likelihood of negative preventive practices towards COVID-19.Conclusions: The participants in this study showed good knowledge, positive attitudes, and good practices toward COVID-19. There is still a need to strategize and implement periodic educational interventions and training on infection control practices among healthcare workers including students. 

scholarly journals Knowledge of anganwadi workers about integrated child development services: a study in Sitamarhi district of Bihar, India

2019 ◽  
Vol 7 (11) ◽  
pp. 4194
Author(s):  
Ravi Ranjan ◽  
Munmee Das ◽  
Shubhabrata Das
Keyword(s):  
Child Development ◽  
Knowledge Score ◽  
Cross Sectional Study ◽  
Growth Monitoring ◽  
Median Score ◽  
Cross Sectional ◽  
Anganwadi Worker ◽  
Score Analysis ◽  
Training Quality ◽  
Level Of Knowledge

Background: The anganwadi worker (AWW) is the backbone of integrated child development services (ICDS) for delivering the services of the program. Being a key functionary, her level of knowledge regarding various components of ICDS is linked to the ultimate outcome of the ICDS program. Thus, this study was aimed to assess the level of knowledge among AWW regarding services of ICDS.Methods: This was a cross sectional study in which level of knowledge regarding ICDS among anganwadi worker was assessed using structured questionnaire. The primary outcome of the study is the knowledge of AWW about ICDS component services. Descriptive statistics was presented as frequency and percentage for categorical variable. The knowledge of AWW was assessed by knowledge score made under all the themes of the questionnaire and was presented as mean and median score. Analysis was done in STATA version 14.2.Results: Nearly 55% of the respondents were not aware about ICDS services. Whereas majority had knowledge on growth monitoring and immunization respectively, above the median score, only 39% of AWW had knowledge on nutritional supplementation above median score. The variables such as education level and training of AWW showed significant association with the knowledge of ICDS components.Conclusions: There is need for improving knowledge and awareness about various ICDS components and the training quality provided to AWWs.

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