Optimised anthropometric indices as predictive screening tools for metabolic syndrome in adults: a cross-sectional study

ObjectivesWe aimed to evaluate the association between metabolic syndrome (MetS) and two latest optimised indices, waist divided by height 0.5 (WHT.5R) and body mass index (BMI) multiply by the square root of BMI and waist circumference (BMI√WC), and to comprehensively compare the ability of 10 anthropometric indices to identify MetS, including BMI√WC, WHT.5R, abdominal volume index (AVI), waist-to-height ratio (WHtR), Body Roundness Index (BRI).DesignCross-sectional study.SettingNingxia, China.ParticipantsA total of 3860 adults aged 18–88 years from Ningxia, China were recruited by a single stratified cluster random sampling method.MethodsORs and 95% CIs for associations between indices and MetS were calculated using binary logistic regression, and areas under the receiver operating characteristic (ROC) curves (AUCs) were performed to compare their predictive capacity for MetS. All results for men and women were analysed and presented separately.ResultsThe highest adjusted ORs for MetS were observed for the following indices: AVI (OR 15.22, 95% CI 10.88 to 21.30), WHT.5R (OR 13.83, 95% CI 9.89 to 19.35) and BMI√WC (OR 12.14, 95% CI 8.79 to 16.76) in men, whereas BRI, WHtR (both OR 14.91, 95% CI 10.39 to 21.4), WHT.5R (OR 14.22, 95% CI 9.96 to 20.29) and AVI (OR 14.03, 95% CI 9.91 to 19.87) in women. In ROC analysis, AVI (AUC: 0.767 for men and 0.749 for women) and WHT.5R (AUC: 0.761 for men and 0.747 for women) showed the highest predictive ability for MetS.ConclusionsBMI√WC and WHT.5R were significantly positively associated with MetS, and AVI and WHT.5R could be useful screening tools for identifying MetS in both sexes.

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Waist-to-Height Ratio Is a Better Anthropometric Index than Waist Circumference and BMI in Predicting Metabolic Syndrome among Obese Mexican Adolescents

International Journal of Endocrinology ◽

10.1155/2014/195407 ◽

2014 ◽

Vol 2014 ◽

pp. 1-9 ◽

Cited By ~ 36

Author(s):

Edel Rafael Rodea-Montero ◽

María Lola Evia-Viscarra ◽

Evelia Apolinar-Jiménez

Keyword(s):

Metabolic Syndrome ◽

Waist Circumference ◽

Roc Curves ◽

Cross Sectional Study ◽

Height Ratio ◽

Anthropometric Indices ◽

Cross Sectional ◽

Obese Adolescents ◽

Waist To Height Ratio ◽

Mexican Adolescents

Objective. To identify the degree of association between anthropometric indices and components of metabolic syndrome (MS) and to determine optimal cut-off points of these indices for predicting MS in obese adolescents.Methods. A cross-sectional study with a sample of (n=110) Mexican obese adolescents grouped by sex and the presence/absence of MS. BMI percentile, waist circumference (WC), and waist-to-height ratio (WHtR) were tested. ROC curves of the anthropometric indices were created to identify whether an index was a significant predictor of MS.Results. BMI percentile, WC, and WHtR were significantly correlated with systolic and diastolic blood pressure. As predictors of MS overall patients, the BMI percentile generated an area under curve (AUC) of 0.651 (P=0.008), cut-off point above the 99th percentile. WC generated an AUC of 0.704 (P<0.001), cut-off point of ≥90 cm. WHtR demonstrated an AUC of 0.652 (P=0.008), cut-off point of 0.60. WHtR ≥0.62 and WHtR ≥0.61 generate AUC of 0.737 (P=0.006) and AUC of 0.717 (P=0.014) for predicting hypertension and insulin resistance, respectively, in females.Conclusion. WHtR is a better tool than WC and BMI for identifying cardiometabolic risk. The overall criterion (WHtR ≥ 0.6) could be appropriate for predicting MS in obese Mexican adolescents.

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Association between metabolic syndrome and thyroid stimulating hormone - A cross sectional study

Medpusle International Journal of Medicine ◽

10.26611/1021922 ◽

2019 ◽

Vol 9 (2) ◽

pp. 87-90

Author(s):

Karanam Madhuri ◽

◽

Rishi Kumar Venkatachalam ◽

A Nasreen Begum ◽

Shamsheer Khan P ◽

...

Keyword(s):

Metabolic Syndrome ◽

Cross Sectional Study ◽

Thyroid Stimulating Hormone ◽

Sectional Study ◽

Cross Sectional ◽

Stimulating Hormone

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USE OF AGE INDEPENDENT ANTHROPOMETRIC INDICES FOR COMPARING THE NUTRITIONAL STATUS OF CHILDREN IN RURAL ICDS AND NON-ICDS VILLAGES: COMMUNITY BASED CROSS SECTIONAL STUDY

National Journal of Research in Community Medicine ◽

10.26727/njrcm.2018.7.2.80-83 ◽

2018 ◽

Vol 7 (2) ◽

pp. 80

Author(s):

Prateek Kumarpanda ◽

Kalpana Panda ◽

Pramod Kumar Panda ◽

Nirnajan Nagaraj

Keyword(s):

Nutritional Status ◽

Cross Sectional Study ◽

Sectional Study ◽

Community Based ◽

Anthropometric Indices ◽

Cross Sectional ◽

Nutritional Status Of Children ◽

Age Independent

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MicroRNAs-1299, -126-3p and -30e-3p as Potential Diagnostic Biomarkers for Prediabetes

Diagnostics ◽

10.3390/diagnostics11060949 ◽

2021 ◽

Vol 11 (6) ◽

pp. 949

Author(s):

Cecil J. Weale ◽

Don M. Matshazi ◽

Saarah F. G. Davids ◽

Shanel Raghubeer ◽

Rajiv T. Erasmus ◽

...

Keyword(s):

Receiver Operating Characteristic ◽

Operating Characteristic ◽

Characteristic Curve ◽

Predictive Ability ◽

Roc Curves ◽

Tolerance Test ◽

Cross Sectional Study ◽

Oral Glucose ◽

Cross Sectional ◽

Receiver Operating

This cross-sectional study investigated the association of miR-1299, -126-3p and -30e-3p with and their diagnostic capability for dysglycaemia in 1273 (men, n = 345) South Africans, aged >20 years. Glycaemic status was assessed by oral glucose tolerance test (OGTT). Whole blood microRNA (miRNA) expressions were assessed using TaqMan-based reverse transcription quantitative-PCR (RT-qPCR). Receiver operating characteristic (ROC) curves assessed the ability of each miRNA to discriminate dysglycaemia, while multivariable logistic regression analyses linked expression with dysglycaemia. In all, 207 (16.2%) and 94 (7.4%) participants had prediabetes and type 2 diabetes mellitus (T2DM), respectively. All three miRNAs were significantly highly expressed in individuals with prediabetes compared to normotolerant patients, p < 0.001. miR-30e-3p and miR-126-3p were also significantly more expressed in T2DM versus normotolerant patients, p < 0.001. In multivariable logistic regressions, the three miRNAs were consistently and continuously associated with prediabetes, while only miR-126-3p was associated with T2DM. The ROC analysis indicated all three miRNAs had a significant overall predictive ability to diagnose prediabetes, diabetes and the combination of both (dysglycaemia), with the area under the receiver operating characteristic curve (AUC) being significantly higher for miR-126-3p in prediabetes. For prediabetes diagnosis, miR-126-3p (AUC = 0.760) outperformed HbA1c (AUC = 0.695), p = 0.042. These results suggest that miR-1299, -126-3p and -30e-3p are associated with prediabetes, and measuring miR-126-3p could potentially contribute to diabetes risk screening strategies.

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Impact of high visceral adiposity index associated with metabolic syndrome on erectile function in sexually active men: results of a cross‐sectional study

International Journal of Clinical Practice ◽

10.1111/ijcp.14111 ◽

2021 ◽

Author(s):

Mustafa Suat Bolat ◽

Mustafa Latif Ozbek ◽

Bekir Şahin ◽

Merve Yılmaz ◽

Fatih Kocamanoglu ◽

...

Keyword(s):

Metabolic Syndrome ◽

Erectile Function ◽

Cross Sectional Study ◽

Visceral Adiposity ◽

Visceral Adiposity Index ◽

Sexually Active ◽

Sectional Study ◽

Cross Sectional ◽

Adiposity Index

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The association between dietary antioxidant quality score with metabolic syndrome and its components in Iranian adults: A cross‐sectional study

Food Science & Nutrition ◽

10.1002/fsn3.2067 ◽

2020 ◽

Author(s):

Mahshid Shahavandi ◽

Hossein Shahinfar ◽

Nastaran payande ◽

Fatemeh Sheikhhossein ◽

Kurosh Djafarian ◽

...

Keyword(s):

Metabolic Syndrome ◽

Cross Sectional Study ◽

Quality Score ◽

Sectional Study ◽

Cross Sectional ◽

Dietary Antioxidant

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Association of Serum Bilirubin Level with Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease: A Cross-Sectional Study of 1672 Obese Children

Journal of Clinical Medicine ◽

10.3390/jcm10132812 ◽

2021 ◽

Vol 10 (13) ◽

pp. 2812

Author(s):

Cristina Bellarosa ◽

Giorgio Bedogni ◽

Annalisa Bianco ◽

Sabrina Cicolini ◽

Diana Caroli ◽

...

Keyword(s):

Metabolic Syndrome ◽

Fatty Liver ◽

Fatty Liver Disease ◽

Serum Bilirubin ◽

Cross Sectional Study ◽

Sectional Study ◽

Obese Children ◽

Cross Sectional ◽

Alcoholic Fatty Liver ◽

Alcoholic Fatty Liver Disease

As in adults, obesity also plays a central role in the development of metabolic syndrome (MS) in children. Non-alcoholic fatty liver disease (NAFLD) is considered a manifestation of MS. Not only MS but also NAFLD seem to be inversely associated with serum bilirubin concentrations, an important endogenous tissue protector when only mild elevated. The aim of the study was to evaluate the association between serum bilirubin levels and the prevalence of MS and NAFLD in Italian obese children and adolescents. A retrospective cross-sectional study was performed in 1672 patients aged from 5 to 18 years. Clinical and laboratory parameters were assessed. NAFLD was measured by liver ultrasonography. The study was approved by the Ethical Committee of the Istituto Auxologico Italiano (research project code 1C021_2020, acronym BILOB). MS was present in 24% and fatty liver (FL) in 38% of this population. Bilirubin was not associated with FL and MS as a whole, but it was inversely associated only with selected components of MS, i.e., large WC, high blood pressure and high triglycerides. Our data suggest that bilirubin is not protective against MS and NAFLD in the presence of severe obesity.

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