scholarly journals High rates of sexually transmitted infections in HIV positive homosexual men: data from two community based cohorts

2007 ◽  
Vol 83 (5) ◽  
pp. 397-399 ◽  
Author(s):  
F. Jin ◽  
G. P Prestage ◽  
I. Zablotska ◽  
P. Rawstorne ◽  
S. C Kippax ◽  
...  
Author(s):  
Krishna C. Poudel ◽  
Kalpana Poudel-Tandukar ◽  
Paula H. Palmer ◽  
Tetsuya Mizoue ◽  
Masamine Jimba ◽  
...  

In Asian concentrated HIV epidemics, data on coinfection of sexually transmitted infections (STIs) among HIV-positive individuals are limited. The authors measured the prevalence of Chlamydia trachomatis (CT), Neisseria gonorrhea (NG), and syphilis, and their correlates among 319 HIV-positive individuals in Kathmandu, Nepal. The authors tested blood samples for syphilis and urine samples for CT and NG. Overall, 17 (5.3%) participants had at least 1 STI (CT: 1.3%, NG: 2.8%, and syphilis: 1.2%). Of 226 participants who had sex in past 6 months, 51.3% did not always use condoms. Older (aged 35-60 years) participants were more likely (adjusted odds ratio [AOR] = 3.83; 95% confidence interval [CI] = 1.19-12.33; P = .024) and those who were currently married (AOR = 0.30; 95% CI = 0.09-0.97; P = .046) or on antiretroviral therapy (AOR = 0.21; 95% CI = 0.06-0.71; P = .012) were less likely to have at least 1 STI. Our results suggest the need to strengthen the efforts to screen and treat STIs and to promote safer sexual practices among Nepalese HIV-positive individuals.


2017 ◽  
Vol 4 (suppl_1) ◽  
pp. S106-S106 ◽  
Author(s):  
Akarin Hiransuthikul ◽  
Nanthika Prawepray ◽  
Supab Pengpum ◽  
Ratchadej Reankhomfu ◽  
Phubet Panpet ◽  
...  

Abstract Background Men who have sex with men (MSM) and transgender women (TG) are at increased risk for sexually transmitted infections (STIs). To understand potential different characteristics, we assessed gender-specific, demographic data, behavioral risks and prevalence of STIs. Methods Thai MSM and TG aged ≥18 years from six community-based organizations in Thailand were enrolled into the Test and Treat cohort during 2015–2016. Baseline demographic and behavior risk assessment and HIV/STIs testing were done. Blood for syphilis serology and pharyngeal and anal swab, and urine for gonorrhea and chlamydia nucleic acid amplification testing were collected. Logistic regression was used to determine factors associated with gender-specific STIs prevalence. Results From 1862 MSM and 787 TG enrolled, 874 (33%) had STI and 402 (15.2%) were HIV-positive. Compared with MSM, more TG were single (79.7% vs. 71.6%), had lower education (23.6% vs. 40% with diploma or higher), had lower income (35.7% vs. 42.6% gained >288 USD/month), had first sex at young age (20.1% vs. 12.8% at <15 years old), and reported >3 sexual partners in the past 6 months (32.9% vs. 24.6%) (all P < 0.001). The overall STIs prevalence was similar between both genders (31.5% vs. 33.6%, P = 0.29), but TG had lower HIV prevalence (8.9% vs. 17.8%, P < 0.001). TG had higher prevalence of pharyngeal and anal chlamydia (5.5% vs. 2.9%, P = 0.001 and 19.5% vs. 15.1%, P = 0.007, respectively), while syphilis prevalence was higher in MSM (9.9% vs. 3.6%, P < 0.001). Among HIV-positive participants, MSM had higher prevalence of HIV and syphilis coinfection (26.2% vs. 8.6%, P = 0.001). STIs prevalence among TG was associated with HIV-positive status (adjusted odd ratio [aOR] 2.74; 95% CI 1.52–4.95, P = 0.001), having multiple sexual partners or refused to answer (aOR 2.36; 95% CI 1.31–4.24, P = 0.004 and 2.33; 95% CI 1.24–4.37, P = 0.009, respectively) and unprotected sexual intercourse (aOR 1.66; 95% CI 1.02–2.69, P = 0.041). Conclusion Almost one-third of TG enrolled into the Test and Treat cohort had STI. TG had lower HIV prevalence but similar STIs prevalence compared with MSM, despite practicing riskier sexual behaviors. Our findings signified the importance of studying TG sexual networks in Thailand to better strategize sexual health programs. Disclosures All authors: No reported disclosures.


2021 ◽  
Author(s):  
Wei Tu ◽  
Yu-Ye Li ◽  
Yi-Qun Kuang ◽  
Rong-Hui Xie ◽  
Xing-Qi Dong ◽  
...  

Abstract Background Yunnan has the highest rates of HIV in the country. Other treatable sexually transmitted infections (STIs) are associated with accelerated HIV transmission and poor ART outcomes, but are only diagnosed by syndromic algorithms. Methods We recruited 406 HIV-positive participants for a cross-sectional study (204 ART-naive and 202 ART). Blood samples and first-voided urine samples were collected. Real-time polymerase chain reaction methods were used for Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG) and Mycoplasma genitalium (MG). Syphilis and HSV-2 tests were also performed. Results Among 406 participants, the overall prevalence of STI was 47.0% and 45.1% in ART-naive individuals and 49.0% in ART individuals, respectively. Testing frequency was 11.6% (11.8% vs 11.4%), 33.2% (29.4% vs 37.1%), 3.2% (3.4% vs 3.0%), 2.0% (3.4% vs 0.5%) and 4.7% (6.4% vs 3.0%) for active syphilis, HSV-2, chlamydia, gonorrhoeae and genitalium. Percentage of multiple infections in both groups was 10.8% (22/204) in ART-naive participants and 9.9% (20/202) in ART participants. Females, age between 18 to 35 years, ever injected drugs, homosexual or bisexual, HIV/HBV coinfection, and not receiving ART were identified as risk factors. Self-reported asymptom was not eliminating of having a laboratory-diagnosed STI. Conclusions STI prevalence was 47.0% (45.1% vs 49.0%), HSV-2, syphilis and MG were the most common STIs in HIV-infected individuals. We found high prevalence (6.4%) of Mycoplasma genitalium in ART-naive individuals. ART can reduce the diversity of STI-HIV coinfection but not the prevalence. HIV-positive individuals tend to neglect or maybe hide their genital tract discomfort, thus we suggest strengthening STI joint screening and treatment services among HIV-infected individuals whether they describe genital tract discomfort or not.


Healthline ◽  
2020 ◽  
Vol 11 (2) ◽  
pp. 72-81
Author(s):  
Anita Punia ◽  
Jyoti Yadav ◽  
Babita ◽  
Sanjay Kumar Jha ◽  
Sanjeet Singh ◽  
...  

Introduction: Reproductive Tract Infections (RTIs) and Sexually transmitted infections (STIs) continue to be a major public health problem and affecting women's health. Objectives: To estimate the prevalence of RTIs/STIs among married women aged 18-49 years in rural areas and to determine the factors associated with these conditions. Method: A community-based cross-sectional study was carried out among 308 eligible married women aged 18-49 years in rural areas in District Sonipat, Haryana using the WHO-Syndromic Approach for diagnosis of RTIs/STIs. Results: The mean age of study subjects in our study was 32.1 years (SD = ± 8.3 years) with a range from 18 to 49 years. The overall RTIs/STIs prevalence was 49.3%. The most frequent symptom was vaginal discharge (55.3%) followed by pain during micturition (34.2%), dyspareunia (26.9%), pain lower abdomen (24.3%) and vulval itching (16.4%). RTI/STI symptoms were found significantly more among women who had history of any chronic disease, who had irregular menstrual cycles, used cloths as sanitary pads and among those whose husbands were substance users. Conclusions: This study revealed a high prevalence (49.3%) of RTIs/STIs. Awareness about symptoms of RTIs, menstrual and personnel hygiene, raising literacy level of women, drive against use of addictive substances etc. by husbands is needed for control and prevention of RTIs. Primary health care services in respect of reproductive health should be strengthened and raising awareness among women about reproductive health issues through suitable communication strategies in order to bring about a positive behavior change for effective control of STIs.


2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S212-S213
Author(s):  
Timothy William. Menza ◽  
Lauren Lipira ◽  
Amisha Bhattarai ◽  
Joseph Ramirez ◽  
Roberto Orellana

Abstract Background Rectal gonorrhea and Chlamydia are common and predict HIV acquisition among men who have sex with men (MSM); however, screening for rectal sexually transmitted infections (STIs) is not routine. Methods In 2017, we recruited sexually-active MSM in the Portland, Oregon metropolitan area through venue-based sampling. Our outcome of interest was self-reported rectal STI screening in the prior 12 months. Stratified by HIV status, we assessed the prevalence and demographic, healthcare, clinical, and behavioral predictors of screening. Results Of 448 participants, 168 (37.5%) reported rectal STI screening. One hundred twenty-seven (35.8%) of 355 HIV-negative men, 41 (58.6%) of 70 HIV-positive men, and none of 23 men who did not know their HIV status reported screening. Among HIV-negative men, having a healthcare provider who offered HIV testing (adjusted prevalence ratio [aPR]=2.09; 95% confidence interval [CI]: 1.43, 3.04), a syphilis diagnosis (aPR=1.32; 95% CI: 1.03, 1.69), use of pre-exposure prophylaxis (aPR=1.57; 95% CI 1.21, 2.04), and condomless anal sex with casual partners in the prior 12 months (aPR=1.74; 95% CI: 1.36, 2.22) independently predicted screening for rectal STI in multivariable analysis. HIV-positive men who reported having a provider who always or often initiates conversations about sex were significantly more likely to report screening compared with men who did not have such a provider (aPR=1.48; 95% CI: 1.06, 2.06). Conclusion Rectal STI screening is not universal in a venue-based sample of sexually-active MSM. Implementing innovative, acceptable, and accessible screening practices and improving provider comfort with talking about sex are paramount to increasing rectal STI screening. Disclosures All authors: No reported disclosures.


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