Evaluating the effect of 20-hydroxyecdysone (20HE) on mechanistic target of rapamycin complex 1 (mTORC1) signaling in the skeletal muscle and liver of rats
2015 ◽
Vol 40
(12)
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pp. 1324-1328
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Keyword(s):
Phytoecdysteroids such as 20-hydroxyecdysone (20HE) are nutritional supplements marketed as enhancers of lean body mass. In this study the impact of 20HE ingestion on protein kinase B/Akt-mechanistic target of rapamycin complex 1 signaling in the skeletal muscle and liver of male rats was found to be limited. Bioavailability of 20HE, whether consumed alone or with leucine, also remained low at all doses ingested. Additional work is necessary to clarify 20HE mechanism of action in vivo.
2018 ◽
Vol 19
(11)
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pp. 3558
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Keyword(s):
2019 ◽
Vol 20
(5)
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pp. 1178
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Keyword(s):
2020 ◽
Vol 19
(2)
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pp. 206-210
2004 ◽
Vol 310
(2)
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pp. 774-782
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Keyword(s):