Gut–Brain Axis: The Current State of Imaging Technologies, Their Clinical Implications, and Future Directions

2021 ◽  
pp. 119-151
Author(s):  
David Tran ◽  
Drew Smith ◽  
Mario M. Perdomo ◽  
Viraj Shah ◽  
Dario Ebode ◽  
...  
Keyword(s):  
Clinical Implications ◽  
Future Directions ◽  
Imaging Technologies ◽  
Current State

Autonomous vehicles and freight traffic: towards better efficiency of road, rail or urban logistics?

2018 ◽  
Vol 58 (1) ◽  
pp. 41-52 ◽  
Author(s):  
Péter Bucsky
Keyword(s):  
Autonomous Vehicles ◽  
Road Transport ◽  
Transport Sector ◽  
Future Directions ◽  
Car Industry ◽  
Level Of Automation ◽  
Current State ◽  
Freight Traffic ◽  
Levels Of Automation ◽  
Private Car

Abstract The freight transport sector is a low profit and high competition business and therefore has less ability to invest in research and development in the field of autonomous vehicles (AV) than the private car industry. There are already different levels of automation technologies in the transport industry, but most of these are serving niche demands and answers have yet to be found about whether it would be worthwhile to industrialise these technologies. New innovations from different fields are constantly changing the freight traffic industry but these are less disruptive than on other markets. The aim of this article is to show the current state of development of freight traffic with regards to AVs and analyse which future directions of development might be viable. The level of automation is very different in the case of different transport modes and most probably the technology will favour road transport over other, less environmentally harmful traffic modes.

scholarly journals A review of current state and future directions of cotton production in Ethiopia

2021 ◽  
Vol 7 (1) ◽  
pp. 1880533
Author(s):  
Tiliksew Addis ◽  
Abera Kachi ◽  
Jun Wang
Keyword(s):  
Cotton Production ◽  
Future Directions ◽  
Current State

scholarly journals Olfaction and Aging: A Review of the Current State of Research and Future Directions

i-Perception ◽  
2021 ◽  
Vol 12 (3) ◽  
pp. 204166952110203
Author(s):  
Jonas K. Olofsson ◽  
Ingrid Ekström ◽  
Maria Larsson ◽  
Steven Nordin
Keyword(s):  
Warning Signs ◽  
Future Directions ◽  
Current State ◽  
Challenging Tasks ◽  
State Of Research ◽  
To Come ◽  
Health Cognition ◽  
Olfactory Abilities ◽  
And Training

Olfaction, the sense of smell, is characterized by a notable age-dependency such that aging individuals are more likely to have poor olfactory abilities. These impairments are considered to be mostly irreversible and as having potentially profound effects on quality of life and food behavior, as well as constituting warning signs of mortality, cognitive dysfunction, and dementia. Here, we review the current state of research on aging and olfaction, focusing on five topics which we regard to be of particular relevance for the field: nutrition and health, cognition and dementia, mortality, environment and genetics, and training-based enhancement. Under each of these headlines, we provide a state-of-the-art overview and discuss gaps in our knowledge which might be filled by further research. Understanding how olfactory abilities are diminished in aging, and how they may be alleviated or recovered, involves a set of challenging tasks for researchers in the years to come.

Personality and Grief-Related Panic Attacks: Analysis of Neuroticism, Worry, and Anxiety Sensitivity

2021 ◽  
pp. 003022282199219
Author(s):  
Sherman A. Lee ◽  
Jamison S. Bottomley
Keyword(s):  
Risk Factor ◽  
Personality Traits ◽  
Anxiety Sensitivity ◽  
Panic Attacks ◽  
Clinical Implications ◽  
Future Directions ◽  
Psychological Reaction ◽  
And Gender

Grief-related panic attacks (GRPAs) are a relatively common yet debilitating psychological reaction to loss, the mechanisms of which remain poorly understood among scholars. The purpose of this study was to identify the personality traits that underlie GRPAs in a sample of 314 bereaved adults. The results indicate that GRPAs were relatively common (55.4%) and that anxiety sensitivity uniquely predicted both frequency and impairment associated with these kinds of attacks, while taking into account the effects of neuroticism, trait worry, grief, and gender. Findings suggest that anxiety sensitivity may be a risk factor for GRPAs and magnified grief for some mourners. Clinical implications and future directions are discussed.

scholarly journals The Hyperloop System and Stakeholders: A Review and Future Directions

2021 ◽  
Vol 13 (15) ◽  
pp. 8430
Author(s):  
Lambros Mitropoulos ◽  
Annie Kortsari ◽  
Alexandros Koliatos ◽  
Georgia Ayfantopoulou
Keyword(s):  
Literature Review ◽  
Online Search ◽  
Future Directions ◽  
Transport Mode ◽  
High Speeds ◽  
Current State ◽  
Comprehensive Literature Review ◽  
Planning Processes ◽  
Holistic Assessment ◽  
The Eu

The hyperloop is an innovative land transport mode for passengers and freight that travels at ultra-high speeds. Lately, different stakeholders have been engaged in the research and development of hyperloop components. The novelty of the hyperloop necessitates certain directions to be followed toward the development and testing of its technological components as well the formation of regulations and planning processes. In this paper, we conduct a comprehensive literature review of hyperloop publications to record the current state of progress of hyperloop components, including the pod, the infrastructure, and the communication system, and identify involved EU stakeholders. Blending this information results in future directions. An online search of English-based publications was performed to finally consider 107 studies on the hyperloop and identify 81 stakeholders in the EU. The analysis shows that the hyperloop-related activities are almost equally distributed between Europe (39%) and Asia (38%), and the majority of EU stakeholders are located in Spain (26%) and Germany (20%), work on the traction of the pod (37%) and the tube (28%), and study impacts including safety (35%), energy (33%), and cost (30%). Existing tube systems and testing facilities for the hyperloop lack full-scale tracks, which creates a hurdle for the testing and development of the hyperloop system. The presented analysis and findings provide a holistic assessment of the hyperloop system and its stakeholders and suggest future directions to develop a successful transport system.

scholarly journals EXPRESS: What’s New in Pulmonary Hypertension Clinical Research: Lessons from the Best Abstracts at the 2020 American Thoracic Society International Conference

2021 ◽  
pp. 204589402110407
Author(s):  
Andrew J Sweatt ◽  
Raju Reddy ◽  
Farbod Rahaghi ◽  
Nadine Al-Naamani
Keyword(s):  
Pulmonary Hypertension ◽  
Clinical Research ◽  
Chronic Thromboembolic Pulmonary Hypertension ◽  
American Thoracic Society ◽  
Future Directions ◽  
International Conference ◽  
Metabolic Dysregulation ◽  
Current State ◽  
Thromboembolic Pulmonary Hypertension ◽  
Pulmonary Arterial

In this conference paper, we review the 2020 American Thoracic Society (ATS) International Conference session titled, “What’s New in Pulmonary Hypertension Clinical Research: Lessons from the Best Abstracts”. This virtual mini-symposium took place on October 21, 2020, in lieu of the annual in-person ATS International Conference which was cancelled due to the COVID-19 pandemic. Seven clinical research abstracts were selected for presentation in the session, which encompassed five major themes: (1) standardizing diagnosis and management of pulmonary hypertension, (2) improving risk assessment in pulmonary arterial hypertension, (3) evaluating biomarkers of disease activity, (4) understanding metabolic dysregulation across the spectrum of pulmonary hypertension, and (5) advancing knowledge in chronic thromboembolic pulmonary hypertension. Focusing on these five thematic contexts we review the current state of knowledge, summarize presented research abstracts, appraise their significance and limitations, and then discuss relevant future directions in pulmonary hypertension clinical research.

A Survey on Document-level Neural Machine Translation

2021 ◽  
Vol 54 (2) ◽  
pp. 1-36
Author(s):  
Sameen Maruf ◽  
Fahimeh Saleh ◽  
Gholamreza Haffari
Keyword(s):  
Machine Translation ◽  
Language Processing ◽  
Research Field ◽  
Translation Process ◽  
Future Directions ◽  
Translation Quality ◽  
Current State ◽  
Evaluation Strategies ◽  
Almost All ◽  
Document Level

Machine translation (MT) is an important task in natural language processing (NLP), as it automates the translation process and reduces the reliance on human translators. With the resurgence of neural networks, the translation quality surpasses that of the translations obtained using statistical techniques for most language-pairs. Up until a few years ago, almost all of the neural translation models translated sentences independently , without incorporating the wider document-context and inter-dependencies among the sentences. The aim of this survey article is to highlight the major works that have been undertaken in the space of document-level machine translation after the neural revolution, so researchers can recognize the current state and future directions of this field. We provide an organization of the literature based on novelties in modelling and architectures as well as training and decoding strategies. In addition, we cover evaluation strategies that have been introduced to account for the improvements in document MT, including automatic metrics and discourse-targeted test sets. We conclude by presenting possible avenues for future exploration in this research field.

scholarly journals Genetic and Transcriptomic Biomarkers in Neurodegenerative Diseases: Current Situation and the Road Ahead

Cells ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 1030
Author(s):  
Julie Lake ◽  
Catherine S. Storm ◽  
Mary B. Makarious ◽  
Sara Bandres-Ciga
Keyword(s):  
Neurodegenerative Diseases ◽  
Large Scale ◽  
Disease Diagnosis ◽  
Open Science ◽  
Future Directions ◽  
The Road ◽  
Current State ◽  
Molecular Complexity ◽  
Science Framework ◽  
Lateral Sclerosis

Neurodegenerative diseases are etiologically and clinically heterogeneous conditions, often reflecting a spectrum of disease rather than well-defined disorders. The underlying molecular complexity of these diseases has made the discovery and validation of useful biomarkers challenging. The search of characteristic genetic and transcriptomic indicators for preclinical disease diagnosis, prognosis, or subtyping is an area of ongoing effort and interest. The next generation of biomarker studies holds promise by implementing meaningful longitudinal and multi-modal approaches in large scale biobank and healthcare system scale datasets. This work will only be possible in an open science framework. This review summarizes the current state of genetic and transcriptomic biomarkers in Parkinson’s disease, Alzheimer’s disease, and amyotrophic lateral sclerosis, providing a comprehensive landscape of recent literature and future directions.

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