Compositions and Biological Activities of Essential Oils of Kadsura longepedunculata and Schisandra sphenanthera

2007 ◽  
Vol 35 (02) ◽  
pp. 353-364 ◽  
Author(s):  
Lei Song ◽  
Jie-Ying Ding ◽  
Cui Tang ◽  
Chun-Hua Yin
Keyword(s):  
Essential Oils ◽  
Antioxidant Activities ◽  
Biological Activities ◽  
Liver Homogenate ◽  
Reducing Power ◽  
Antimicrobial Activities ◽  
Dilution Method ◽  
Chemical Compositions ◽  
Dependent Manner ◽  
Schisandra Sphenanthera

The chemical compositions, antimicrobial activities, antioxidant activities and cytotoxicities of the essential oils isolated from the root of Kadsura longepedunculata Finet et Gagnep (KLREO) and the fruit of Schisandra sphenanthera Rehd. et Wills. (SSFEO) were investigated.The analyses of gas chromatography-mass spectrometry (GC-MS) showed that cadinane type compounds and their derivatives were rich in both oils (54.2% and 39.7%, respectively) and δ-cadinene was the major component of both oils (13.8% and 25.6%, respectively). The antimicrobial activities of both oils were evaluated against five microorganisms with the disc diffusion and the broth micro-dilution method. Results showed that Gram-positive bacteria were more sensitive to both oils than Gram-negative bacteria and the yeast. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the oil of KLREO were lower than those of SSFEO, indicating that the former possessed slightly stronger antibacterial capability than the latter. The reducing power and lipid peroxidation assays were employed to study the potential antioxidant activities of both oils. Both oils remarkably decreased the content of malondialdehyde (MDA) in rat liver homogenate in a dose dependent manner. The antioxidant activities of KLREO appeared to be more potent than that of SSFEO. The oils of KLREO and SSFEO exhibited concentration-dependent cytotoxicities and were proved to be toxic to HepG2 cells with IC50 of 147 and 189 μg/ml, respectively.

scholarly journals Chemical Composition and Antioxidant and Antimicrobial Activities of Wormwood (Artemisia absinthiumL.) Essential Oils and Phenolics

2015 ◽  
Vol 2015 ◽  
pp. 1-12 ◽  
Author(s):  
Kamel Msaada ◽  
Nidhal Salem ◽  
Olfa Bachrouch ◽  
Slim Bousselmi ◽  
Sonia Tammar ◽  
...  
Keyword(s):  
Gas Chromatography ◽  
Essential Oil ◽  
Essential Oils ◽  
Methanolic Extract ◽  
Biological Activities ◽  
Reducing Power ◽  
Antimicrobial Activities ◽  
Gas Chromatography Mass Spectrometry ◽  
Oil Composition ◽  
Antioxidant And Antimicrobial Activities

The aim of this study was to determine the chemical variability of wormwood extracts as affected by the growing region. Antioxidant and antimicrobial activities were also investigated. The essential oil composition variability ofA. absinthiumL. aerial parts collected from four different Tunisian regions was assessed by gas chromatography (GC/FID) and by gas chromatography mass spectrometry (GC/MS). In addition, total polyphenols, flavonoids, and condensed tannins as well as antioxidant, antibacterial, and antifungal activities of methanolic extract and essential oils were undertaken. Chromatographic analysis of wormwood essential oils showed the predominance of monoterpene hydrocarbons represented mainly by chamazulene. RP-HPLC analysis of wormwood methanolic extract revealed the predominance of phenolic acids. Antiradical activity was region-dependant and the methanolic extract of Bou Salem region has the strongest activity (CI50=9.38±0.82 µg/mL). Concerning the reducing power, the methanolic extract of Bou Salem, Jérissa, and Boukornine regions was more active than the positive control. Obtained results of antimicrobial activities showed that wormwood essential oil is endowed with important antibacterial activity which was strongly related to the organoleptic quality of oil which appeared strongly region-dependant.A. absinthiumL. EOs investigated are quite interesting from a pharmaceutical standpoint because of their biological activities.

scholarly journals Chemical Compositions and Antimicrobial Activity of the Essential Oils of Piper abbreviatum, P. erecticaule and P. lanatum (Piperaceae)

2014 ◽  
Vol 9 (12) ◽  
pp. 1934578X1400901 ◽  
Author(s):  
Wan Mohd Nuzul Hakimi Wan Salleh ◽  
Farediah Ahmad ◽  
Khong Heng Yen
Keyword(s):  
Antimicrobial Activity ◽  
Essential Oils ◽  
Antimicrobial Agents ◽  
Antimicrobial Activities ◽  
Dilution Method ◽  
Chemical Compositions ◽  
Gram Positive Bacteria ◽  
Aerial Parts ◽  
Ms Analysis ◽  
Weak Activity

The study was designed to examine the chemical composition and antimicrobial activities of essential oils extracted from the aerial parts of three Piper species: Piper abbreviatum, P. erecticaule and P. lanatum, all from Malaysia. GC and GC/MS analysis showed qualitative and quantitative differences between these oils. GC and GC-MS analysis of P. abbreviatum, P. erecticaule and P. lanatum oils resulted in the identification of 33, 35 and 39 components, representing 70.5%, 63.4% and 78.2% of the components, respectively. The major components of P. abbreviatum oil were spathulenol (11.2%), ( E)-nerolidol (8.5%) and β-caryophyllene (7.8%), whereas P. erecticaule oil mainly contained β-caryophyllene (5.7%) and spathulenol (5.1%). Borneol (7.5%), β-caryophyllene (6.6%) and α-amorphene (5.6%) were the most abundant components in P. lanatum oil. Antimicrobial activity was carried out using disc diffusion and broth micro-dilution method against nine microorganisms. All of the essential oils displayed weak activity towards Gram-positive bacteria with MIC values in the range 250–500 μg/mL. P. erecticaule oil showed the best activity on Aspergillus niger (MIC 31.3 μg/mL), followed by P. lanatum oil (MIC 62.5 μg/mL). This study demonstrated that the essential oils have potential as antimicrobial agents and may be useful in the pharmaceutical and cosmetics industries.

scholarly journals PHYTOCHEMICAL SCREENING, ANTIOXIDANT AND ANTIMICROBIAL ASSESSMENT OF PLUCHEA INDICA (L.) LESS EXTRACT AS AN ACTIVE INGREDIENT IN NATURAL LOTION BAR

2021 ◽  
pp. 51-57
Author(s):  
SIRIKHWAN TINRAT
Keyword(s):  
Broad Spectrum ◽  
Antioxidant Activities ◽  
Biological Activities ◽  
Radical Scavenging ◽  
Ethanolic Extract ◽  
Antimicrobial Activities ◽  
Dilution Method ◽  
Reducing Ability ◽  
Phytochemical Compounds ◽  
Antioxidant And Antimicrobial Activities

Objective: To screen phytochemical compounds and study antioxidant and antimicrobial activities of Pluchea indica (L.) Less (PI) leaves extracts for assessment the moisturizing lotion bar formulation containing it’s as a bioactive ingredient. Methods: PI leaves were extracted in different solvents. Crude extracts were screened phytochemical compounds and evaluated antioxidant and antimicrobial activities before formulating to antibacterial moisturizing lotion bar. Results: 95% ethanolic extract displayed high antioxidant activities. DPPH radical scavenging capacity with IC50 was 6.80±0.04 mg/ml (61.37±0.41%) and the ferric reducing ability power was 381.20±0.10 mg AAE/100 gDW. Additionally, 95% ethanolic extract served as a broad spectrum bacteriostatic agents against gram-positive and gram-negative species with an inhibition zone of 6.50±0.00-46.67±0.58 mm. It also was simultaneously as a broad spectrum bactericidal agents (MIC and MBC value of 25-200 mg/ml) by broth micro-dilution method. The screened phytochemical constituents (saponins, tannins, flavonoids, terpenoids, steroids, and alkaloids) in PI leaves extract may be responsible for high biological activities. Thus, 95% ethanolic extract was the most appropriate bioactive ingredient for formulated the product development. Conclusion: The developed moisturizing lotion bar with 0.0041% of 95% ethanolic extract was the most eligible formula that showed good appearance, odor, color, homogeneity, after feel and stability. This extract-containing lotion bar formulation achieved a high level of customer satisfaction by sensory evaluation and development of this specific formulation should be subject to further clinical investigation.

scholarly journals Essential Oil Extracted from Cymbopogon citronella Leaves by Supercritical Carbon Dioxide: Antioxidant and Antimicrobial Activities

2019 ◽  
Vol 2019 ◽  
pp. 1-10 ◽  
Author(s):  
Hong Wu ◽  
Jilie Li ◽  
Yuan Jia ◽  
Zhihong Xiao ◽  
Peiwang Li ◽  
...  
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Antioxidant Activities ◽  
Oil Quality ◽  
Antimicrobial Activities ◽  
Oil Yield ◽  
Chemical Compositions ◽  
Extraction Temperature ◽  
Experimental Conditions ◽  
Essential Oil Yield

To improve essential oil quality, especially to reserve the thermal instability of compounds, supercritical CO2 extraction (SFE) was applied to recover essential oil from Cymbopogon citronella leaves. A response surface methodology was applied to optimize the extraction process. The highest essential oil yield was predicted at extraction time 120  min, extraction pressure 25  MPa, extraction temperature 35°C, and CO2 flow 18  L/h for the SFE processing. Under these experimental conditions, the mean essential oil yield is 4.40%. In addition, the chemical compositions of SFE were compared with those obtained by hydrodistillation extraction (HD). There were 41 compounds obtained of SFE, while 35 compounds of HD. Alcohols and aldehydes were the main compositions in the essential oils. Furthermore, the antioxidant activities and antimicrobial of essential oils obtained by HD and the evaluated condition of SFE were compared. Results showed that the antioxidant activities of SFE oil are better than those of HD. Minimum inhibitory concentrations (MICs) were determined by the microdilution method. Essential oil obtained from SFE and HD exhibited a significant antimicrobial activity against all tested microorganisms. It is confirmed that the SFE method can be an alternative processing method to extract essential oils from Cymbopogon citronella leaves.

scholarly journals Chemical Composition, Antimicrobial, Antioxidant and Cytotoxic Activity of Essential Oils of Plectranthus cylindraceus and Meriandra benghalensis from Yemen

2012 ◽  
Vol 7 (8) ◽  
pp. 1934578X1200700 ◽  
Author(s):  
Nasser A. Awadh Ali ◽  
Martina Wurster ◽  
Annika Denkert ◽  
Norbert Arnold ◽  
Iman Fadail ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Essential Oils ◽  
Cytotoxic Activity ◽  
Antioxidant Activities ◽  
Antimicrobial Activities ◽  
Dilution Method ◽  
Cytotoxic Activities ◽  
Moderate Activity ◽  
Inhibition Zones ◽  
Total Oil

The chemical composition, antimicrobial, antioxidant and cytotoxic activities of the essential oils isolated from the leaves of Plectranthus cylindraceus Hoechst. ex. Benth. (EOPC) and Meriandra benghalensis (Roxb.) Benth. (EOMB) were investigated. Sixteen compounds were identified in P. cylindraceus oil representing 94.5% of the oil content with thymol (68.5%), terpinolene (5.3%), β-selinene (4.7%), β-caryophyllene (4.0%), δ-cadinol (2.1%), and ar-curcumene (1.7%) as the major compounds. In M. benghalensis oil, 12 compounds were identified, which made up 82.0% of the total oil. The most abundant constituents were camphor (43.6%), 1,8-cineole (10.7%), α-eudesmol (5.8%), caryophyllene oxide (5.8%), camphene (5.3%) and borneol (3.4%). The antimicrobial activities of both oils were evaluated against five microorganisms with the disc diffusion test, the broth micro-dilution method and a semiquantitative bioautographic test. The most sensitive microorganisms for P. cylindraceus oil were S. aureus, B. subtilis, and C. albicans with inhibition zones of 38, 42, and 43 mm and MIC values of 0.39, 0.18, and, 0.18 μL/mL, respectively. M. benghalensis oil showed weak to moderate activity against the tested microorganisms. 2,2-Diphenyl-1-picrylhydrazyl (DPPH) assay was employed to study the potential antioxidant activities of both oils. The antioxidant activity of P. cylindraceus oil (IC50 34.5 μg/mL) appeared to be higher than that of M. benghalensis oil (IC50 935 μg/mL). At a concentration of 100 μg/mL, EOMB showed a stronger cytotoxic activity, with growth inhibition of 71% against HT29 tumor cells, than EOPC (18%).

scholarly journals Enhancement of Phenolics Content and Biological Activities of Longan (Dimocarpus Longan Lour.) Treated with Thermal and Aging Process

2021 ◽  
Author(s):  
Preaploy Hong-in ◽  
Waranya Neimkhum ◽  
Chanun Punyoyai ◽  
Suwannee Sri ◽  
Wantida Chaiyana
Keyword(s):  
High Performance ◽  
Antioxidant Activities ◽  
Biological Activities ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Aluminium Chloride ◽  
Chemical Compositions ◽  
Dimocarpus Longan ◽  
Phenolics Content

Abstract This study is the first to successfully produce novel black Dimocarpus longan by undergoing thermal and ageing process. Pericarp, aril, and seed of black D. longan were macerated in 95% v/v ethanol. Their chemical compositions were investigated by Folin–Ciocalteu assay, aluminium chloride assay, and high-performance liquid chromatography. Antioxidant activities were evaluated in terms of radical scavenging and iron (III) reducing capacity. Enzyme inhibitory assay was used to evaluate the hyaluronidase inhibition. Black D. longan seed extract contained the significantly highest content of flavonoids and phenolic compounds (p < 0.05). Each gram of the extract contained 53.6 ± 0.9 mg of gallic acid, 19.8 ± 2.9 mg of corilagin, and 24.5 ± 0.7 mg of ellagic acid. This extract was the most potent anti-hyaluronidase and antioxidant with the strongest free radical scavenging activity and reducing power. Therefore, it was proposed as functional food and further used in the pharmaceutical or cosmeceutical industries.

scholarly journals The Chemical Compositions, and Antibacterial and Antioxidant Activities of Four Types of Citrus Essential Oils

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3412
Author(s):  
Xiaocai Lin ◽  
Shan Cao ◽  
Jingyu Sun ◽  
Dongliang Lu ◽  
Balian Zhong ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Essential Oils ◽  
Antioxidant Activities ◽  
Antibacterial Activities ◽  
Inhibitory Effect ◽  
Chemical Compositions ◽  
Citrus Reticulata ◽  
Dependent Manner ◽  
Citrus Reticulata Blanco ◽  
Broth Microdilution Method

Nanfeng mandarins (Citrus reticulata Blanco cv. Kinokuni), Xunwu mandarins (Citrus reticulata Blanco), Yangshuo kumquats (Citrus japonica Thunb) and physiologically dropped navel oranges (Citrus sinensis Osbeck cv. Newhall) were used as materials to extract peel essential oils (EOs) via hydrodistillation. The chemical composition, and antibacterial and antioxidant activities of the EOs were investigated. GC-MS analysis showed that monoterpene hydrocarbons were the major components and limonene was the predominate compound for all citrus EOs. The antibacterial testing of EOs against five different bacteria (Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Salmonella typhimurium) was carried out using the filter paper method and the broth microdilution method. Kumquat EO had the best inhibitory effect on B. subtilis, E. coli and S. typhimurium with MIC (minimum inhibitory concentration) values of 1.56, 1.56 and 6.25 µL/mL, respectively. All citrus EOs showed the antioxidant activity of scavenging DPPH and ABTS free radicals in a dose-dependent manner. Nanfeng mandarin EO presented the best antioxidant activity, with IC50 values of 15.20 mg/mL for the DPPH assay and 0.80 mg/mL for the ABTS assay. The results also showed that the antibacterial activities of EOs might not be related to their antioxidant activities.

scholarly journals Chemical Compositions, Antioxidant and Antimicrobial Activity of the Essential Oils of Piper officinarum (Piperaceae)

2012 ◽  
Vol 7 (12) ◽  
pp. 1934578X1200701 ◽  
Author(s):  
Wan Mohd Nuzul Hakimi Wan Salleh ◽  
Farediah Ahmad ◽  
Khong Heng Yen ◽  
Hasnah Mohd Sirat
Keyword(s):  
Linoleic Acid ◽  
Essential Oils ◽  
Antioxidant Activities ◽  
Radical Scavenging ◽  
Antimicrobial Activities ◽  
Total Phenolic ◽  
Chemical Compositions ◽  
Weak Activity ◽  
Lipid Peroxidation Inhibition ◽  
Β Carotene

This study was designed to investigate the antioxidant and antimicrobial activities of the essential oils from Piper officinarum C. DC. GC and GC/MS analysis of the leaf and stem oils showed forty one components, representing 85.6% and 93.0% of the oil, respectively. The most abundant components in the leaf oil were β-caryophyllene (11.2%), α-pinene (9.3%), sabinene (7.6%), β-selinene (5.3%) and limonene (4.6%), while β-caryophyllene (10.9%), α-phellandrene (9.3%), linalool (6.9%), limonene (6.7%) and α-pinene (5.0%) were the main components of the stem oil. The antioxidant activities were determined by using complementary tests: namely β-carotene-linoleic acid, DPPH radical scavenging and total phenolic assays. The stems oil showed weak activity (IC50 = 777.4 μg/mL) in the DPPH system, but showed moderate lipid peroxidation inhibition in the β-carotene-linoleic acid system (88.9 ± 0.35%) compared with BHT (95.5 ± 0.30%). Both oils showed weak activity against P. aeruginosa and E. coli with M IC values of 250 μg/mL.

scholarly journals Antimicrobial and Antioxidant Activities of Flavonoids Extracted from Pistacia lentiscus L., Leaves

2020 ◽  
Vol 10 (1-s) ◽  
pp. 83-89
Author(s):  
Sabrina Bakli ◽  
Harzallah Daoud ◽  
Zerroug Amina ◽  
Sadrati Nouari ◽  
Bouguerra Asma ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Inhibitory Concentration ◽  
Solid Medium ◽  
Minimum Bactericidal Concentration ◽  
Antioxidant Activities ◽  
Biological Activities ◽  
Reducing Power ◽  
Dilution Method ◽  
Pistacia Lentiscus ◽  
The Subject

Increasingly, the flavonoids becoming the subject of biomedical researches, and many groups have isolated and identified the structures of flavonoids possessing important biological activities. This assess investigates the antimicrobial fight and the antioxidant strengths of flavonoids extracted from Pistacia lentiscus L. leaves.  The extract was first analyzed for its phenolic content, then the flavonoids were tested for their antimicrobial capacities by the method of diffusion against fourteen bacteria, two fungi and one yeast. The minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) of flavonoids were determined using the dilution method on solid medium, however, the antioxidant activity was evaluated through the ability of the extract to scavenge DPPH (1,1-diphenyl-2-picrylhydrazyl) radicals and the reducing power essay. The results indicate that flavonoids extract contain other phenolics groups. On the other side, the Antibacterial tests exhibited different activities depending on the strains. Unlike, the MIC and the MBC showed that the flavonoids extract showed a best activity against Candida albicans and Vibrio cholerae. Concerning antioxidant activity, the results indicate a moderate capacity of the flavonoid extract. These preliminary results may justify the use of this plant in the treatment of some diseases and may be exploited for therapeutic purposes. Keywords: Antimicrobial, Antioxidant, Pistacia lentiscus, flavonoids, MIC, MBC.

Chemical variability and antioxidant activities of the essential oils of the aerial parts of Ammoides verticillata and the roots of Carthamus caeruleus and their synergistic effect in combination

2020 ◽  
Vol 23 ◽  
Author(s):  
Imane Rihab Mami ◽  
Noria Merad-Boussalah ◽  
Mohammed El Amine Dib ◽  
Boufeldja Tabti ◽  
Jean Costa ◽  
...  
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Antioxidant Activities ◽  
Radical Scavenging Activity ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Natural Food ◽  
Chemical Compositions ◽  
Chemical Variability ◽  
Ammoides Verticillata

Aim and Objective: Oxidative stress is implicated in the development and progression of many disease. Some of appropriate actions that could be initiated to taken to resolve the problem of these diseases are search for new antioxidant substances isolated from plants. The aims of this study were to study the intraspecies variations of A. verticillata and C. caeruleus essential oils from 8 locations using statistical analysis, the in vitro antioxidant properties of collective essential oils and in combinations. Materials and Methods: The essential oils were analyzed by GC and GC-MS. The intraspecies variations of the essential oil compositions were discussed using principal component analysis (PCA) and cluster analysis (CA). The antioxidant properties were evaluated DPPH-radical scavenging activity and β-carotene bleaching test. Results: The main components of Ammoides verticillata collective essential oil (Coll EO) were thymol (30.5%), carvacrol (23.2%), p-cymene (13.1%), limonene (12.5%) and terpinene-4-ol (12.3%). While roots of Carthamus caeruleus essential oil were dominated by carline oxide (86.2%). The chemical variability allowed the discrimination of two main Groups for both Coll EOs. A direct correlation between the altitudes, climate and the chemical compositions was evidenced. Ammoides verticulata and Carthamus caeruleus Coll Eos showed good antioxidant activity. In binary mixture, the interaction both Coll Eos and between oils rich of thymol and/or carvacrol with carlina oxide produced the best synergistic effects, compared to individual essential oils and the synthetic antioxidant (BHT). Conclusion: Ammoides verticillata and Carthamus caeruleus essential oil blends can be used as a natural food preservative and alternative to chemical antioxidants.

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