MMPI Manifestations of Chinese Migraine Syndromes: A Control Study

1999 ◽  
Vol 27 (01) ◽  
pp. 37-42 ◽  
Author(s):  
Arthur Yin Fan ◽  
An-Nan Zhou

The investigation of personality traits of patients suffering from migraine headache with the Minnesota Multiphasic Personality Inventory (MMPI) is an important line of research, and differentiating syndromes in treating this disease is one of the characteristics of Chinese Medicine (CM). This study presents the MMPI-(Chinese edition) responses of 80 Chinese subjects with migraine and 40 non-headache healthy control subjects. Among them, migraine fire syndrome (MF) group consisted of 45 subjects (10 men, 35 women); migraine Qi stasis syndrome (MQ) group, 35 subjects (8 men, 27 women). The healthy control group was divided into healthy Qi stasis syndrome (HQ) group, 9 subjects (2 men, 7 women); and healthy normal (HN) group, 31 subjects (7 men, 24 women) according to CM diagnostic criteria. Statistical analysis was performed by pairs among four groups. The results revealed that both MF and MQ groups' MMPI profiles were significantly higher than that of the Normal (HN) group, and formed a 1.2.3.7 type slope. Profile deviation in the MQ group was slight, but in the MF group was serious and accompanied by a significant rising scores in F, paranoia (6), schizophrenia (8) and social introversion (0) subtests; HQ group's MMPI profile had a similar deviation as in the MQ group. The results suggest that CM migraine syndromes have an exact expression on MMPI profile, and that MMPI as an effective diagnostic method could be applied for CM syndrome discrimination. The "deviation of migraineurs' personality" may not be a special characteristic held only by migraineurs. The existence of different syndromes in migraine is one of the reasons that different scholars have reported different results on migraine by means of MMPI.

2011 ◽  
Vol 26 (S2) ◽  
pp. 1198-1198
Author(s):  
K. Farnikova ◽  
R. Obereigneru ◽  
J. Prasko ◽  
P. Kanovsky

This was a case control study involving 46 patients suffering from Parkinson disease (PD); 13 with impulse control disorder (ICD) and 33 without ICD; and 56 controls. The personality traits in these groups were analyzed using the Minnesota Multiphasic Personality Inventory-2 (MMPI-2). 46 patients with PD and 56 control group subjects were included into study. ICD were identified in 13 patients from PD group. There were higher scores than pathological threshold (65) in four domains of MMPI-2 Clinical scales: D (Depression), Pt (Psychastenia), Sc (Schizophrenia) and SI (Social introversion) in PD patients with ICD; but there were not statistical difference in any of these scales in comparison with the group of PD patients without ICD. In the case of MMPI-2 Subscales and Content scales there were higher scores than pathological threshold in eight domains of MMPI-2: SOD (Social Discomfort), PD4 (Psychopatic deviate - social alienation), PA1 (Paranoia - persecutory ideas), SC1 (Schizophrenia), PA_O (Paranoia - subtle), MA_O (Hypomania - obvious), SI1 (Syness/Self-Consciousness), SI3 (Alienation self and others) and Ho (Hostility), but there were statistical differences only in one of these domains in comparison with the PD patients without ICD: SI3 (alienation self and others). There was earlier onset of the disease and higher dose of levodopa in PD patients with ICD than in PD patients without ICD.Supported by project IGA MZ ČR NS 10301-3/2009


2019 ◽  
Vol 3 (1) ◽  
pp. 18-28 ◽  
Author(s):  
Sandy Shabaan Hassan ◽  
Gihane Gharib Madkour ◽  
Ramy Wahba Henin ◽  
Selvia Wahib Fayek Gad ◽  
Amany Ahmed Abd El-Aal

Background: Entamoeba gingivalis was the first commensal parasite detected in the oral cavity of humans, and a high incidence has been reported in patients with poor oral hygiene. The current study aimed to investigate the association of Entamoeba gingivalis with gingivitis and periodontitis among Egyptian subjects. Methods: A total of 120 plaque samples were collected for this case-control study and were divided as follows: 40 plaque samples from gingivitis patients (group 1), 40 from stage II grade A and B periodontitis patients (group 2), and 40 samples from healthy volunteers (group 3). Diagnosis of parasitic stages relied on direct microscopic detection using permanent stains, trichrome stain, and hematoxylin and eosin (H&E) stain, in addition to ocular micrometry to confirm the diagnosis. Results: The occurrence of Entamoeba gingivalis within the gingivitis group was significantly higher (40%) than that observed in the control group (22.5%), whereas the occurrence within the periodontitis group was 15%. Samples from diseased subjects, regardless of immune status, were found to be moderately to severely affected with numerous parasitic nests, in contrast to a moderate near mild occurrence that was recorded in the healthy control group. Moreover, Entamoeba gingivalis occurrence was significantly higher (77.4%) in subjects with bad oral hygiene. Conclusion: The results of the present study suggest a potential role for the neglected oral parasitic Entamoeba gingivalis, especially the intensively multiplying forms, in the pathogenesis of periodontal diseases. This certainly needs further elucidation on a larger scale to explore the basis behind such multiplication, which may be related to genetic variation or may be pathophysiological in origin.


1997 ◽  
Vol 10 (4) ◽  
pp. 117-120 ◽  
Author(s):  
M. Malinchoc ◽  
W. A. Rocca ◽  
R. C. Colligan ◽  
K. P. Offord ◽  
E. Kokmen

Linking data from a case–control study of Alzheimer’s disease with data from a Minnesota Multiphasic Personality Inventory (MMPI) outpatient study, we identified 13 Alzheimer's disease cases and 16 controls for case–control comparison. The mean time between personality testing and onset of Alzheimer's disease (or corresponding age for controls) was 13 years in cases and 14 years in controls. Alzheimer's disease cases, but not the controls, had scores significantly greater than the normative reference on MMPI scales measuring Social Introversion (p = 0.05), and Pessimism (p = 0.01). When compared to controls, Alzheimer's disease cases had significantly greater scores on the Social Introversion scale (p = 0.03). Despite the small sample size and some design limitations of this exploratory study, our findings may suggest that subjects who score higher on these personality scales have a greater risk of Alzheimer's disease.


Author(s):  
Adnan Adil Hismiogullari ◽  
Gurhan Guney ◽  
Mine Islimye Taşkın ◽  
Berna Güngörmus

Objectives: ADAMTS (A Disintegrin And Metalloproteinase with ThromboSpondin repeats) proteinases, which are released outside the cell (soluble) have very critical roles in damage and repair of extracellular matrix (ECM) processes. Our aim was to analyse the ADAMTS-1 and ADAMTS-9 which were the member of the ADAMTS gene family of metalloproteinases that might had been involved in the cytokines-mediated etiopathogenesis of endometriosis. Methods: A case-control study was performed in an university hospital. Thirty-four patient with endometriosis which was defined via laparoscopy and thirty-three healthy female volunteers were recruited in the present study. Serum ADAMTS-1 and ADAMTS-9 and IL-beta (IL-1 β) and vascular endothelial growth factor (VEGF) levels were determined by a human enzyme-linked immunoassay (ELISA) in all subjects. Results: The demographic characteristics of the patients were significantly higher than healthy control group. The IL-1 β and VEGF levels were significantly higher; ADAMTS-1 and ADAMTS-9 levels were significantly lower in the endometriosis patients compared to the controls. We also found a negative correlation between ADAMTS-1, ADAMTS-9, and IL-1 β, VEGF. Conclusion: The results of the study might suggest that ADAMS-1 and ADAMTS-9 have a role in the pathogenesis of the endometriosis.


Author(s):  
Özer Akgül ◽  
Ömer Faruk Demirel ◽  
Cana Poyraz Aksoy ◽  
Ezgi Tanrıöver Aydın ◽  
Nuray Uysal ◽  
...  

Introduction: The opinion that latent T. gondii infection is having a broadly asymptomatic projection has now been interrogated, in specific due to the echoed association between the latent infection and an elevated incidence of schizophrenia or even suicide attempts. Notwithstanding conducted studies aimed to understand this feasible link are restricted. Methods: In the present case-control study, we focused to illuminate the relationship between the serological and molecular presence of T. gondii and schizophrenia with or without the suicide attempts by comparing it with healthy individuals. A total of 237 participants (117 in schizophrenia; 120 in healthy control) were included in this study. Results: Overall, latent T. gondii infections were found statistically higher in 63 (53.8%) of the 117 patients with schizophrenia and in 33 (27.5%) of the 120 controls (p < 0.001). In schizophrenia patients, seroprevalence T. gondii was again found to be statistically higher in suicide attempters (59.6%), compared to no history of suicide attempts (48.3%) (p < 0.05). The molecular positivity rate of T. gondii DNA was higher in the schizophrenia group, compared to the healthy control group (p < 0.05), whereas the history of suicide attempts was not statistically associated (p = 0.831) with T. gondii DNA positivity by PCR. Conclusion: This case-control study enlightens additional demonstration to the belief that T. gondii infection would be an underlying component for the pathophysiology of schizophrenia. Regardless of the clarity results of this study, this supposition warrants further endorsement.


2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Amelie Therrien ◽  
Simon Bouchard ◽  
Sacha Sidani ◽  
Mickael Bouin

Background. Patients with chronic pancreatitis (CP) exhibit numerous risk factors for the development of small intestinal bacterial overgrowth (SIBO).Objective. To determine the prevalence of SIBO in patients with CP.Methods. Prospective, single-centre case-control study conducted between January and September 2013. Inclusion criteria were age 18 to 75 years and clinical and radiological diagnosis of CP. Exclusion criteria included history of gastric, pancreatic, or intestinal surgery or significant clinical gastroparesis. SIBO was detected using a standard lactulose breath test (LBT). A healthy control group also underwent LBT.Results. Thirty-one patients and 40 controls were included. The patient group was significantly older (53.8 versus 38.7 years;P< 0.01). The proportion of positive LBTs was significantly higher in CP patients (38.7 versus 2.5%:P< 0.01). A trend toward a higher proportion of positive LBTs in women compared with men was observed (66.6 versus 27.3%;P= 0.056). The subgroups with positive and negative LBTs were comparable in demographic and clinical characteristics, use of opiates, pancreatic enzymes replacement therapy (PERT), and severity of symptoms.Conclusion. The prevalence of SIBO detected using LBT was high among patients with CP. There was no association between clinical features and the risk for SIBO.


2021 ◽  
Vol 33 (1) ◽  
Author(s):  
Gehad Abd El-Shaker Abd El-Hay ◽  
Salah Abdelazim Argoon ◽  
Naglaa Mohamed M. A. Mousa

Abstract Background Metabolic syndrome (MetS) and thyroid dysfunction have a degree of close association, and each of them affects the other. Due to the associated cardiovascular events, MetS has increased morbidity and mortality. The study tried to detect the frequency of thyroid function in patients with MetS. This is a case control study that recruited 100 patients with MetS and 100 healthy control subjects. Results Patients with MetS had significantly higher body mass index and waist circumference. Also, frequency of thyroid dysfunction was significantly higher in MetS group (32% vs. 9%; P<0.001). The most frequent form of thyroid dysfunction was subclinical hypothyroidism: 21% of the MetS group and 6% of the control group. Out of the studied patients with MetS, 13 (13%) patients had three criteria, 55 (55%) patients had four criteria, and 32 (32%) patients had five criteria for MetS. Conclusion Patients with MetS are vulnerable to develop thyroid dysfunction mainly subclinical hypothyroidism. So, it is recommended to perform regular screening for those patients as regard thyroid dysfunction.


2021 ◽  
Vol 66 (6) ◽  
pp. 39-44
Author(s):  
A. Kosenkov

Purpose: To propose a procedure for comparative analysis of correlation relationships structure between psychological scales in samples of different sizes. Material and methods: A procedure of comparative analysis of correlation relationships structure between psychological indicators in groups of different sizes based on the «zet» method of R. Fisher is proposed. To illustrate the method, data from psychodiagnostic surveys of the nuclear power plant (NPP) personnel who worked in normal conditions and the personnel of the Chernobyl NPP at four different stages of aftermath activities in 1986–1987 were used. All the subjects performed the Minnesota Multiphasic Personality Inventory (MMPI); the results of each of the groups were subjected to a correlation analysis using the Pearson method. The analysis took into account average (0.5 ≤ r < 0.7) and strong (r ≥ 0.7) correlations. Results: Using the example of a number of psychodiagnostic examinations of the Chernobyl NPP personnel at various stages of aftermath activities, it is shown that the structure of correlation relationships between the MMPI scales can reflect the peculiarities of mental adaptation of professional teams working in regular and extreme conditions. It was shown that in the aftermath process by March–April 1987, the number of medium and strong pairwise Pearson correlations between the clinical MMPI scales increased. This fact apparently indicates that during this period, the NPP personnel were characterized by the simultaneous activation of various mechanisms of intrapsychic adaptation. The core of the correlation pleiad consisted of scales 1, 2, 7, and 8. Such a multidirectional reaction to the aftermath stressors was accompanied by a statistically significant increase in almost all clinical scales (except scale 6) of the average MMPI profile in comparison with the control group. The absence of stable correlations of clinical scales with the F scale indicates that the marked increase in the MMPI profile was not associated with a tendency to aggravation. By the period of November–December 1987, the hypochondria scale occupied a leading place in the correlation pleiad of the MMPI indicators of the Chernobyl NPP personnel, the number of its significant connections with other clinical scales (2, 3, 7 and 8) reached four. Apparently, the mechanism of anxiety somatization at that time could be considered as a syndrome-forming factor and taken into account when planning rehabilitation and health measures. Conclusion: The use of the proposed method of the strength standardization of pairwise correlation relationships between the MMPI scales allowed us to legitimately compare these indicators in groups that differ significantly in number. The chosen representation form of correlations facilitates the analysis of their structure.


2018 ◽  
Vol 129 (01) ◽  
pp. 36-42 ◽  
Author(s):  
Nafez Abu Tarboush ◽  
Nakhleh E Abu-Yaghi ◽  
Laith H Al Ejeilat ◽  
Rawand K. Abdel Wahed ◽  
Issa N Jeris

AbstractObesity and obesity induced type 2 diabetes development and progression have been associated with sedentary lifestyle. Irisin, a newly discovered myokine, has been demonstrated at lower levels in obese and type 2 diabetes patients compared to controls. The main aim of this study is to explore association of Irisin with diabetic retinopathy (DR). A total of 233 healthy and adults participated in this study. Participants were divided into four categories: a healthy control group and an age-match subset of patients with type 2 diabetes; a positive control group of patients with type 2 diabetes not affected by DR (No DR); and patients with type 2 diabetes affected by DR (non-proliferative DR (NPDR) and proliferative DR (PDR)). Plasma samples were quantified for Irisin measurement, lipid profile and HbA1c. Comparison of the age-matched groups of healthy controls and patients with type 2 diabetes revealed lower Irisin plasma level in type 2 diabetes group. Analyses revealed negative correlations of Irisin to HbA1c and LDL levels and positive correlation to HDL level. Comparing Irisin level in No DR and DR groups revealed a higher level in No DR group and analysis per DR classification indicated higher Irisin level in NPDR group. Our results demonstrate not only correlation of plasma Irisin level with DR stages, but also significantly different Irisin level among them. This is promising in terms of researching Irisin as a potential associating marker for type 2 diabetes and DR development and progression.


2007 ◽  
Vol 101 (1) ◽  
pp. 323-333 ◽  
Author(s):  
Rebekkah Greenfield ◽  
Paul M. Valliant

To evaluate moral reasoning and personality, inmates from a maximum security jail were administered the Porteus Maze, the Defining Issues Test, the Minnesota Multiphasic Personality Inventory-168, and the Test of Nonverbal Intelligence. Scores of 20 violent and 19 nonviolent offenders were compared. The control group consisted of 20 university students who indicated they did not have criminal records. All were over the age of 18. Analysis showed the violent offenders had mature moral reasoning and were more elevated on the Antiestablishment scale of the Defining Issues Test. Furthermore, inmates displayed significantly elevated scores on depression, Psychopathic Deviance, and Social Introversion relative to the control group.


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