Structural Mechanisms for Replicating DNA in Eukaryotes

2021 ◽  
Vol 90 (1) ◽  
Author(s):  
Ilan Attali ◽  
Michael R. Botchan ◽  
James M. Berger
Keyword(s):  
Nucleic Acid ◽  
Online Publication ◽  
Recent Progress ◽  
Molecular Machines ◽  
Cellular Process ◽  
Annual Review ◽  
Publication Date ◽  
Working Together ◽  
Protein Nucleic Acid ◽  
Structural Mechanisms

The faithful and timely copying of DNA by molecular machines known as replisomes depends on a disparate suite of enzymes and scaffolding factors working together in a highly orchestrated manner. Large, dynamic protein–nucleic acid assemblies that selectively morph between distinct conformations and compositional states underpin this critical cellular process. In this article, we discuss recent progress outlining the physical basis of replisome construction and progression in eukaryotes. Expected final online publication date for the Annual Review of Biochemistry, Volume 90 is June 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

scholarly journals Cancer Immunotherapy and the Nectin Family

2020 ◽  
Vol 5 (1) ◽  
Author(s):  
Robert J. Johnston ◽  
Peter S. Lee ◽  
Pavel Strop ◽  
Mark J. Smyth
Keyword(s):  
Immune Response ◽  
Cancer Immunotherapy ◽  
Online Publication ◽  
Cancer Biology ◽  
Recent Progress ◽  
Clinical Development ◽  
Annual Review ◽  
Publication Date ◽  
Immune Response To Cancer

It is increasingly clear that the nectin family and its immunoreceptors shape the immune response to cancer through several pathways. Yet, even as antibodies against TIGIT, CD96, and CD112R advance into clinical development, biological and therapeutic questions remain unanswered. Here, we review recent progress, prospects, and challenges to understanding and tapping this family in cancer immunotherapy. Expected final online publication date for the Annual Review of Cancer Biology, Volume 5 is March 4, 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

New Directions in the Study of Institutional Logics: From Tools to Phenomena

2021 ◽  
Vol 47 (1) ◽  
Author(s):  
Michael Lounsbury ◽  
Christopher W.J. Steele ◽  
Milo Shaoqing Wang ◽  
Madeline Toubiana
Keyword(s):  
Recent Work ◽  
Online Publication ◽  
Institutional Logics ◽  
Annual Review ◽  
Publication Date ◽  
Complex Dynamic ◽  
New Directions ◽  
Analytical Tools ◽  
Dynamic Phenomena

In this article, we take stock of the institutional logics perspective and highlight opportunities for new scholarship. While we celebrate the growth and generativity of the literature on institutional logics, we also note that there has been a troubling tendency in recent work to use logics as analytical tools, feeding disquiet about reification and reductionism. Seeding a broader scholarly agenda that addresses such weaknesses in the literature, we highlight nascent efforts that aim to more systematically understand institutional logics as complex, dynamic phenomena in their own right. In doing so, we argue for more research that probes how logics cohere and endure by unpacking the role of values, the centrality of practice, and the governance dynamics of institutional logics and their orders. Furthermore, we encourage bridging the study of institutional logics with various literatures, including ethnomethodology, phenomenology, professions, elites, world society, and the old institutionalism, to enhance progress in these directions. Expected final online publication date for the Annual Review of Sociology, Volume 47 is July 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

Advances in Morphological Theory: Construction Morphology and Relational Morphology

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Jenny Audring
Keyword(s):  
Online Publication ◽  
Mental Lexicon ◽  
Research Community ◽  
Annual Review ◽  
Publication Date ◽  
Theory Construction ◽  
Construction Morphology ◽  
Challenges And Opportunities ◽  
Morphological Theory

In recent years, construction-based approaches to morphology have gained ground in the research community. This framework is characterized by the assumption that the mental lexicon is extensive and richly structured, containing not only a large number of stored words but also a wide variety of generalizations in the form of schemas. This review explores two construction-based theories, Construction Morphology and Relational Morphology. After outlining the basic theoretical architecture, the article presents an array of recent applications of a construction-based approach to morphological phenomena in various languages. In addition, it offers reflections on challenges and opportunities for further research. The review highlights those aspects of the theory that have proved particularly helpful in accommodating both the regularities and the quirks that are typical of the grammar of words. Expected final online publication date for the Annual Review of Linguistics, Volume 8 is January 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

The Political Economy of Attention

2021 ◽  
Vol 50 (1) ◽  
Author(s):  
Morten Axel Pedersen ◽  
Kristoffer Albris ◽  
Nick Seaver
Keyword(s):  
Political Economy ◽  
Online Publication ◽  
The Political ◽  
Annual Review ◽  
Publication Date ◽  
Moral Concern ◽  
Digital Platforms ◽  
Political Economic

Attention has become an issue of intense political, economic, and moral concern over recent years: from the commodification of attention by digital platforms to the alleged loss of the attentional capacities of screen-addicted children (and their parents). While attention has rarely been an explicit focus of anthropological inquiry, it has still played an important if mostly tacit part in many anthropological debates and subfields. Focusing on anthropological scholarship on digital worlds and ritual forms, we review resources for colleagues interested in this burgeoning topic of research and identify potential avenues for an incipient anthropology of attention, which studies how attentional technologies and techniques mold human minds and bodies in more or less intentional ways. Expected final online publication date for the Annual Review of Anthropology, Volume 50 is October 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

Recent Research on the Archaeology of War and Violence

2021 ◽  
Vol 50 (1) ◽  
Author(s):  
Andrew K. Scherer
Keyword(s):  
State Formation ◽  
Online Publication ◽  
General Trend ◽  
Annual Review ◽  
Publication Date ◽  
Modern Times ◽  
The Past ◽  
Definition Of ◽  
Consequences Of Violence

The mid-1990s through the first decade of the new millennium marked an increase in publications pertaining to war and violence in the ancient past. This review considers how scholars of the past decade have responded to that work. The emerging consensus is that war and violence were endemic to all societies studied by archaeologists, and yet the frequency, intensity, causes, and consequences of violence were highly variable for reasons that defy simplistic explanation. The general trend has been toward archaeologies of war and violence that focus on understanding the nuances of particular places and historical moments. Nevertheless, archaeologists continue to grapple with grand narratives of war, such as the proposition that violence has decreased from ancient to modern times and the role of war and violence in state formation and collapse. Recent research also draws attention to a more expansive definition of violence. Expected final online publication date for the Annual Review of Anthropology, Volume 50 is October 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

Confronting Banking Crises: Lessons from the Field

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Marc Dobler ◽  
Marina Moretti ◽  
Alvaro Piris
Keyword(s):  
Financial Crisis ◽  
Online Publication ◽  
Financial Crises ◽  
Global Financial Crisis ◽  
Banking Crises ◽  
Lessons Learned ◽  
Annual Review ◽  
Publication Date ◽  
Policy Interventions ◽  
Comprehensive Framework

Financial crises are a recurring feature of modern economies. This article summarizes the lessons learned from policy interventions and tools used to resolve banking crises from a practical, operational perspective and in light of the experiences and challenges faced during and since the 2008 global financial crisis. Managing a systemic banking crisis is a complex, multiyear process and requires a comprehensive framework for addressing systemic banking problems while minimizing taxpayers’ costs. Expected final online publication date for the Annual Review of Financial Economics, Volume 13 is March 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

Design and Control of Drones

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Mark W. Mueller ◽  
Seung Jae Lee ◽  
Raffaello D’Andrea
Keyword(s):  
Energy Consumption ◽  
Motion Planning ◽  
Recent Progress ◽  
Scaling Laws ◽  
Autonomous Systems ◽  
Annual Review ◽  
Publication Date ◽  
Trade Offs ◽  
Active Research ◽  
And Control

The design and control of drones remain areas of active research, and here we review recent progress in this field. In this article, we discuss the design objectives and related physical scaling laws, focusing on energy consumption, agility and speed, and survivability and robustness. We divide the control of such vehicles into low-level stabilization and higher-level planning such as motion planning, and we argue that a highly relevant problem is the integration of sensing with control and planning. Lastly, we describe some vehicle morphologies and the trade-offs that they represent. We specifically compare multicopters with winged designs and consider the effects of multivehicle teams. Expected final online publication date for the Annual Review of Control, Robotics, and Autonomous Systems, Volume 5 is May 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

Particle-Laden Turbulence: Progress and Perspectives

2021 ◽  
Vol 54 (1) ◽  
Author(s):  
Luca Brandt ◽  
Filippo Coletti
Keyword(s):  
Fluid Dynamics ◽  
Fluid Mechanics ◽  
Online Publication ◽  
Granular Media ◽  
Finite Size ◽  
Spherical Particles ◽  
Annual Review ◽  
Publication Date ◽  
Zero Gravity ◽  
Inertial Particles

This review is motivated by the fast progress in our understanding of the physics of particle-laden turbulence in the last decade, partly due to the tremendous advances of measurement and simulation capabilities. The focus is on spherical particles in homogeneous and canonical wall-bounded flows. The analysis of recent data indicates that conclusions drawn in zero gravity should not be extrapolated outside of this condition, and that the particle response time alone cannot completely define the dynamics of finite-size particles. Several breakthroughs have been reported, mostly separately, on the dynamics and turbulence modifications of small inertial particles in dilute conditions and of large weakly buoyant spheres. Measurements at higher concentrations, simulations fully resolving smaller particles, and theoretical tools accounting for both phases are needed to bridge this gap and allow for the exploration of the fluid dynamics of suspensions, from laminar rheology and granular media to particulate turbulence. Expected final online publication date for the Annual Review of Fluid Mechanics, Volume 54 is January 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

scholarly journals Bacteriophage-Bacteria Interactions in the Gut: From Invertebrates to Mammals

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Joshua M. Kirsch ◽  
Robert S. Brzozowski ◽  
Dominick Faith ◽  
June L. Round ◽  
Patrick R. Secor ◽  
...  
Keyword(s):  
Immune System ◽  
Environmental Conditions ◽  
Online Publication ◽  
Annual Review ◽  
Publication Date ◽  
Microbiota Composition ◽  
Complex Environment ◽  
Health And Disease ◽  
Polymicrobial Communities ◽  
Diverse Interactions

Bacteria and their viruses (bacteriophages or phages) interact antagonistically and beneficially in polymicrobial communities such as the guts of animals. These interactions are multifaceted and are influenced by environmental conditions. In this review, we discuss phage-bacteria interactions as they relate to the complex environment of the gut. Within the mammalian and invertebrate guts, phages and bacteria engage in diverse interactions including genetic coexistence through lysogeny, and phages directly modulate microbiota composition and the immune system with consequences that are becoming recognized as potential drivers of health and disease. With greater depth of understanding of phage-bacteria interactions in the gut and the outcomes, future phage therapies become possible. Expected final online publication date for the Annual Review of Virology, Volume 8 is September 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

Postcolonial Semiotics

2021 ◽  
Vol 50 (1) ◽  
Author(s):  
Angela Reyes
Keyword(s):  
Online Publication ◽  
Continuous Production ◽  
Linguistic Anthropology ◽  
Annual Review ◽  
Publication Date ◽  
Economic Interests ◽  
Recent Scholarship ◽  
The Creation

This article provides an overview of recent scholarship on postcolonial semiotics: processes through which linguistic and other signs are linked to the colonial and its ongoing relevance in the construction of value. After tracing the question of colonialism across scholarly lineages in linguistic anthropology, this article focuses on elite formations as a key realm within postcolonial semiotics and on “fake,” “mix,” and “excess” as central qualities that constitute chronotopically anchored dimensions of ambivalent, aspirational postcolonial eliteness. Linguistic anthropological work on postcolonial elite formations illuminates how economic interests are advanced through the creation of ambiguous value around emblems presupposed as colonial and attached to differentiated elite types in fractally recursive forms. Scholarship on postcolonial semiotics reveals how colonial hierarchies persist through the continuous production of divisible interior alterities that create nested categories of the formerly colonized, inventing elite types that are both denigrated and admired for their supposed approximation to imperial modes of being and speaking. Expected final online publication date for the Annual Review of Anthropology, Volume 50 is October 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

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