scholarly journals The Role of Optical Radiations in Skin Cancer

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Fabrizio Ayala ◽  
Marco Palla ◽  
Rossella Di Trolio ◽  
Nicola Mozzillo ◽  
Paolo A. Ascierto
Keyword(s):  
Skin Cancer ◽  
Ultraviolet Radiation ◽  
Uv Radiation ◽  
Infrared Radiation ◽  
Optical Radiation ◽  
Biological Effects ◽  
Strong Association ◽  
Public Information ◽  
Visible Spectrum ◽  
Clear Correlation

Purpose. Electromagnetic radiation with wavelength in the range 100 nm to 1 mm is known as optical radiation and includes ultraviolet radiation, the visible spectrum, and infrared radiation. The deleterious short- and long-term biological effects of ultraviolet radiation, including melanoma and other skin cancers, are well recognized. Infrared radiation may also have damaging biological effects. Methods. The objective of this review was to assess the literature over the last 15 years and to summarize correlations between exposure to optical radiation and the risk of melanoma and other cancers. Results. There is a clear correlation between exposure to UV radiation and the development of skin cancer. Most importantly, a strong association between artificial UV radiation exposure, for example, tanning devices, and the risk of melanoma and squamous cell carcinoma has been clearly demonstrated. There is no clear evidence that exposure to IR and laser radiation may increase the risk of skin cancer, although negative health effects have been observed. Conclusions. Preventative strategies that involve provision of public information highlighting the risks associated with exposure to sunlight remain important. In addition, precautionary measures that discourage exposure to tanning appliances are required, as is legislation to prevent their use during childhood.

Skin temperature during sunbathing – relevance for skin cancer

2014 ◽  
Vol 13 (8) ◽  
pp. 1123-1125 ◽  
Author(s):  
Bibi Petersen ◽  
Peter Alshede Philipsen ◽  
Hans Christian Wulf
Keyword(s):  
Skin Cancer ◽  
Ultraviolet Radiation ◽  
Skin Temperature ◽  
Infrared Radiation

It has been found that exposure to heat and infrared radiation (IR) can be carcinogenic, and that a combination of ultraviolet radiation (UVR) and IR possibly amplifies carcinogenesis.

scholarly journals Use of ultraviolet radiation in modern medicine (Literature review).

2019 ◽  
Vol 21 (3) ◽  
pp. 30-36
Author(s):  
P S Markevich ◽  
A V Alekhnovich ◽  
A M Kislenko ◽  
A A Esipov
Keyword(s):  
Clinical Practice ◽  
Literature Review ◽  
Ultraviolet Radiation ◽  
Uv Radiation ◽  
Biological Effects ◽  
Biological Tissues ◽  
Modern Medicine ◽  
Therapeutic Effects ◽  
High Importance ◽  
Practical Medicine

The article describes the main directions and areas of application of ultraviolet radiation in clinical practice. A special place is given to the mechanisms of biological effects of ultraviolet radiation, therapeutic effects, as well as the main indications, contraindications, equipment for the use of this method of treatment at the present time. Ultraviolet radiation in all possible methods and methods of delivery to biological tissues is of high importance in modern practice, effectively used in most sections of medicine - surgery, urology, gynecology, dermatology, pulmonology, cardiology, otorhinolaryngology, hematology, immunology and many others. This forms the basis for a wider introduction of UV radiation, further improvement of equipment and methods of its application in practical medicine.

scholarly journals Ultraviolet radiation and melanogenesis

2004 ◽  
Vol 12 (4) ◽  
pp. 203-205 ◽  
Author(s):  
Milenko Stanojevic ◽  
Zorica Stanojevic ◽  
Dragan Jovanovic ◽  
Milena Stojiljkovic
Keyword(s):  
Free Radicals ◽  
Visible Light ◽  
Uv Radiation ◽  
Infrared Radiation ◽  
Biological Effects ◽  
Radiation Energy ◽  
Light Radiation ◽  
Melanin Synthesis ◽  
Protection Mechanisms

Light radiation is a part of the electromagnetic radiation, and it consists of the ultraviolet (UV) radiation, visible light, and infrared radiation. UV radiation energy is absorbed in the form of photons in biomolecules (chromophores) and induces various cellular reactions, out of which photochemical and photosensitizing are the most significant. In contact with the skin UV radiation incites protection mechanisms: the most important are stratum corneum thickening and melanin synthesis (melanogenesis). Basic role of melanin is absorption and scattering of UV rays and neutralization of free radicals. In this review physical characteristics of UV radiation, its biological effects, and relation to melanogenesis and carcinogenesis are discussed.

Ultraviolet Absorbers for Textiles

2010 ◽  
Vol 14 (1) ◽  
pp. 42-52 ◽  
Author(s):  
B.R. Das ◽  
S.M. Ishtiaque ◽  
R.S. Rengasamy ◽  
S. Hati ◽  
A. Kumar
Keyword(s):  
Skin Cancer ◽  
Ultraviolet Radiation ◽  
Human Skin ◽  
Uv Radiation ◽  
Skin Surface ◽  
Textile Material ◽  
The Sun ◽  
Skin Damage ◽  
Uv Absorbers ◽  
Ultraviolet Absorbers

The incidences of skin cancer have been rising worldwide due to excessive exposure to sunlight. Increase in exposure to ultraviolet (UV) radiation from sunlight results in skin damage such as sunburn, premature skin ageing, allergies and skin cancer. Medical experts suggest several means of protection against ultraviolet radiation, including use of sunscreens, avoidance of the sun at its highest intensities, and wearing clothing that covers as much of the skin surface as possible. This paper provides insight on how UV absorbers can be efficiently used with textile material to protect human skin from harmful UV radiation. The manufacturers of various UV absorbers and their commercial products are reviewed and discussed. The interacting mechanism of UV absorbers with textile clothing for providing UV protection and an evaluation of the performance of UV absorbers are summarized.

scholarly journals Overall study on molecular pathways of skin cancer derived from Ultra- violet radiation as an environmental threat

2015 ◽  
Vol 16 (SE) ◽  
pp. 547-555
Author(s):  
Hossein Yousefi ◽  
Samira Mohammadzadeh ◽  
Arsalan Irompour ◽  
Neda Shenasifam ◽  
Elham Roshandel ◽  
...  
Keyword(s):  
Skin Cancer ◽  
Ultraviolet Radiation ◽  
Cell Carcinoma ◽  
Uv Radiation ◽  
Ultra Violet ◽  
Ozone Layer ◽  
Molecular Pathways ◽  
Ultra Violet Radiation ◽  
Environmental Threat ◽  
Violet Radiation

An important part of solar radiation is considered to be Ultraviolet radiation. Though through passing ozone layer it is progressively filtered. Due to the depletion of the ozone layer, the filtering activity of the latter is reduced and as a result more UV radiation, UVB in particular, reaches the Earth’s surface. Ultraviolet radiation is composed of three different wavelengths: UVA, UVB and UVC. Although UVC isn't a cause of skin cancer, UVA and UVB play different roles as for tanning, burning, and photo aging. As a matter of fact, Ultraviolet light can damage DNA in the epidermis. However, through apoptosis the damaged DNA is repaired or deleted in order to prevent the generation of cancer. It is believed that a deficient apoptotic mechanism might make individuals liable to skin cancer. The main factor for generating skin cancer is considered to be the UV radiation which could cause basal cell carcinoma, squamous cell carcinoma and possibly melanoma. For the maintenance of hemostasis, apoptosis plays a key role. This is done via many molecular pathways such as the pathways of tumor suppressor genes like P53, P21 and also the expression of BAX proteins. These pathways are involved in apoptosis after UV radiation. It is clear that the malfunction of these genes and proteins can lower the tolerance of body and cause cancer. The goal of this article is to investigate the molecular pathways of skin cancer derived from Ultra violet radiation as an environmental threat.

Multiple Keratoacanthomas Arising Post-UVB Therapy

2004 ◽  
Vol 8 (4) ◽  
pp. 239-243 ◽  
Author(s):  
Kenneth J. Craddock ◽  
Jaggi Rao ◽  
Gilles J. Lauzon ◽  
Victor A. Tron
Keyword(s):  
Adverse Effect ◽  
Squamous Cell Carcinoma ◽  
Skin Cancer ◽  
Cell Carcinoma ◽  
Uv Radiation ◽  
Squamous Cell ◽  
Etiologic Agent ◽  
Etiologic Factor ◽  
Uv Treatment ◽  
Uvb Phototherapy

Background: Ultraviolet (UV) radiation is known to be an important etiologic agent in the development of skin cancer. Keratoacanthoma is an unusual, well-described cutaneous neoplasm that resembes squamous cell carcinoma but spontaneously resolves. Rarely, multiple keratoacanthomas may develop. Objective We present a case of multiple keratoacanthomas in a patient with psoriasis who had received UVB phototherapy. These lesions were hyperkeratotic papules, many of which spontaneously resolved and demonstrated the histologic characteristics of keratoacanthoma. Conclusion: We believe that UV radiation is the most likely etiologic factor in this patient's development of multiple keratoacanthomas. We wish to bring to the attention of clinicians this unusual adverse effect of UV treatment.

scholarly journals Differential Role of Basal Keratinocytes in UV-Induced Immunosuppression and Skin Cancer

2006 ◽  
Vol 26 (22) ◽  
pp. 8515-8526 ◽  
Author(s):  
Judith Jans ◽  
George A. Garinis ◽  
Wouter Schul ◽  
Adri van Oudenaren ◽  
Michael Moorhouse ◽  
...  
Keyword(s):  
Skin Cancer ◽  
Biological Effects ◽  
Mouse Skin ◽  
Cell Type ◽  
Cell Type Specificity ◽  
Basal Keratinocytes ◽  
Expression Of Genes ◽  
Pyrimidine Dimers ◽  
Response To Stress

ABSTRACT Cyclobutane pyrimidine dimers (CPDs) and 6-4 photoproducts (6-4PPs) comprise major UV-induced photolesions. If left unrepaired, these lesions can induce mutations and skin cancer, which is facilitated by UV-induced immunosuppression. Yet the contribution of lesion and cell type specificity to the harmful biological effects of UV exposure remains currently unclear. Using a series of photolyase-transgenic mice to ubiquitously remove either CPDs or 6-4PPs from all cells in the mouse skin or selectively from basal keratinocytes, we show that the majority of UV-induced acute effects to require the presence of CPDs in basal keratinocytes in the mouse skin. At the fundamental level of gene expression, CPDs induce the expression of genes associated with repair and recombinational processing of DNA damage, as well as apoptosis and a response to stress. At the organismal level, photolyase-mediated removal of CPDs, but not 6-4PPs, from the genome of only basal keratinocytes substantially diminishes the incidence of skin tumors; however, it does not affect the UVB-mediated immunosuppression. Taken together, these findings reveal a differential role of basal keratinocytes in these processes, providing novel insights into the skin's acute and chronic responses to UV in a lesion- and cell-type-specific manner.

Study of the dynamics of the qualitative indicator of champignons during storage after treatment with UV radiation in the A range

2021 ◽  
pp. 56-57
Author(s):  
Наталья Игоревна Федянина ◽  
Ольга Вячеславовна Карастоянова ◽  
Надежда Вячеславовна Коровкина
Keyword(s):  
Mathematical Model ◽  
Radiation Dose ◽  
Ultraviolet Radiation ◽  
Uv Radiation ◽  
Storage Capacity ◽  
Optimal Processing ◽  
Target Indicator ◽  
Processing Modes

Представлены результаты исследования влияния обработки свежих шампиньонов ультрафиолетовым излучением в диапазоне А различными дозами на изменение текстуры. Построена математическая модель зависимости предельной хранимоспособности по целевому показателю грибов от дозы облучения, и установлены оптимальные режимы обработки. The results of a study of the effect of processing fresh champignons with ultraviolet radiation in the A range with various doses on the change in texture are presented. A mathematical model of the dependence of the limiting storage capacity for the target indicator of mushrooms on the radiation dose has been built and the optimal processing modes have been established.

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