scholarly journals Clinical Correlates of Hachinski Ischemic Score and Vascular Factors in Cognitive Function of Elderly

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Youn Ho Kim ◽  
Oh Dae Kwon
Keyword(s):  
Cognitive Function ◽  
Family History ◽  
Rural Community ◽  
Significant Relationship ◽  
Community Dwelling ◽  
Education History ◽  
Clinical Dementia Rating ◽  
History Of ◽  
The Relationship ◽  
State Examination

The aim of this study is to investigate the relationship between Hachinski ischemic score (HIS) and vascular factors as well as between HIS and the cognitive function in elderly community. Demographic characteristics, such as sex, age, education, history of drinking and smoking, family history of dementia and stroke, diabetes mellitus, hypertension, hyperlipidemia, cardiovascular disease, stroke, and dementia, were surveyed. Neurological examination was administered to every subject and HIS was checked by a neurologist. From a total of 392 participants aged 65 and over in a rural community, 348 completed the survey and were finally enrolled. Among the vascular factors, history of hypertension (P=0.008), history of stroke (P<0.001), family history of dementia (P=0.01), and history of cardiac diseases (P=0.012) showed a significant relationship with HIS. In the cognitive function tests, both Korean version of the Mini-Mental State Examination and the Clinical Dementia Rating (Global and Sum of Boxes) had a significant relationship with HIS. Our study suggested HIS may have an association with some vascular factors and cognitive scales in community dwelling elderly. In this study, the HIS seemed to contribute to the evaluation of the quantity of vascular factors and to the prediction of status of cognitive function.

scholarly journals ANALISIS FUNGSI KOGNITIF PADA LANSIA DITINJAU DARI JENIS KELAMIN, RIWAYAT PENDIDIKAN, RIWAYAT PENYAKIT, AKTIVITAS FISIK, AKTIVITAS KOGNITIF, DAN KETERLIBATAN SOSIAL

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Arti Febriyani Hutasuhut ◽  
Marisa Anggraini ◽  
Reza Angnesti
Keyword(s):  
Physical Activity ◽  
Cognitive Function ◽  
Significant Relationship ◽  
Social Engagement ◽  
Cognitive Activity ◽  
The Elderly ◽  
Education History ◽  
Chi Square ◽  
Cross Sectional ◽  
History Of

ABSTRACT: ANALYSIS OF COGNITIVE FUNCTIONS IN ELDERLY IN TERMS OF GENDER, EDUCATION HISTORY, DISEASE HISTORY, PHYSICAL ACTIVITY, COGNITIVE ACTIVITIES, AND SOCIAL ENGAGEMENT One of the disorders caused by degeneration in the elderly is cognitive impairment This study aims to determine the factors that influence cognitive function in the elderly in the work area of the Kedaton Bandar Lampung Health Center in 2018. This research is an analytical survey with a cross-sectional approach. The research subjects were 107 elderly people living in the working area of the Kedaton Health Center in Bandar Lampung. Data in this study were obtained through interviews using questionnaires, social disengagement scale, and MMSE. Data analyzed using chi-square test. The results showed that there was a significant relationship between education, history of illness, physical activity, cognitive activity, and social involvement with cognitive function, whereas for sex, no significant relationship was found with cognitive function. Keywords:  Cognitive Function, Gender, Educational History, History of Illness, Physical Activity, Cognitive Activity, Social Engagement, Elderly Salah satu gangguan akibat degenerasi pada lansia yaitu gangguan kognitif. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang mempengaruhi fungsi kognitif pada lansia di wilayah kerja Puskesmas Kedaton Bandar Lampung tahun 2018. Penelitian ini merupakan survey analitik dengan pendekatan cross-sectional. Subyek penelitian adalah 107 orang lansia yang tinggal di wilayah kerja Puskesmas Kedaton Bandar Lampung. Data dalam penelitian ini diperoleh melalui wawancara menggunakan kuesioner, skala social disengagement, dan MMSE. Analisis data menggunakan uji chi-square. Hasil penelitian menunjukan bahwa terdapat hubungan yang signifikan antara pendidikan, riwayat penyakit, aktivitas fisik, aktivitas kognitif, dan keterlibatan sosial dengan fungsi kognitif, sedangkan untuk jenis kelamin, tidak ditemukan hubungan signifikan dengan fungsi kognitif.  Kata Kunci : Fungsi Kognitif, Jenis Kelamin, Riwayat Pendidikan, Riwayat Penyakit, Aktivitas Fisik, Aktivitas Kognitif, Keterlibatan Sosial, Lansia

Abstract P014: Lower eGFR and Proteinuria Were Independently Associated With Lower Cognitive Abilities in Community-dwelling Men in Japan: SESSA study

Circulation ◽  
2017 ◽  
Vol 135 (suppl_1) ◽  
Author(s):  
Akira Fujiyoshi ◽  
Takayoshi Ohkubo ◽  
Katsuyuki Miura ◽  
Akihiko Shiino ◽  
Naoko Miyagawa ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Cognitive Abilities ◽  
Estimated Glomerular Filtration Rate ◽  
Subclinical Atherosclerosis ◽  
Community Dwelling ◽  
Community Based ◽  
Lower Egfr ◽  
The Mean ◽  
The Relationship

Introduction: The relationship between chronic kidney disease (CKD) and cognitive function remains to be determined. Existing studies focused primarily on estimated glomerular filtration rate (eGFR) but not proteinuria in relation to cognitive function. Hypothesis: In a community-based sample, lower eGFR and presence of proteinuria are cross-sectionally independently associated with lower cognition. Methods: The Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA) randomly recruited and examined participants from Shiga, Japan in 2006-08 at baseline. Among 824 male participants in the follow-up exam (2010-12), we restricted our analyses to those who underwent the Cognitive Abilities Screening Instrument (CASI), age ≥65 years-old, free of stroke, with no missing pertinent covariates. We calculated eGFR (creatinine-based) according to the 2012-guideline by the Japanese Society of Nephrology. We then divided the participants into three groups by eGFR of ≥60, 59-40, and <40 (mL/min/1.73m 2 ), and separately divided into three groups according to proteinuria using urine dipstick: (-), (-/+), and ≥(1+). We defined CKD as either eGFR <60 or proteinuria ≥ (-/+). In linear regression with CASI score being a dependent variable, we computed the score adjusted for age, highest education attained, smoking, drinking, body mass index, hypertension, diabetes, and dyslipidemia. Results: We analyzed 541 men. The mean [standard deviation] of age and unadjusted score were 72.6 [4.3] years and 89.7 [6.0]. Prevalence of CKD was 56%. The score was significantly lower in participants with CKD than those without it (P=0.03). eGFR and proteinuria categories were separately and jointly associated with lower CASI score in a graded fashion (Ps for trend <0.05 in all the models tested. Table 1 ). Conclusions: Lower eGFR and higher degree of proteinuria were independently associated with lower cognitive function in the community-based men. CKD even in its early phase may predispose to lower cognitive function.

Family History of Dementia and Current Depression in Nondemented Community-Dwelling Older Adults

2000 ◽  
Vol 13 (2) ◽  
pp. 65-71 ◽  
Author(s):  
Dylan G. Harwood ◽  
Warren W. Barker ◽  
Raymond L. Ownby ◽  
Michael J. Mullan ◽  
Ranjan Duara
Keyword(s):  
Older Adults ◽  
Family History ◽  
Community Dwelling ◽  
History Of ◽  
Community Dwelling Older Adults

scholarly journals Association between change in handgrip strength and cognitive function in Korean adults: a longitudinal panel study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hyunkyu Kim ◽  
Seung Hoon Kim ◽  
Wonjeong Jeong ◽  
Sung-In Jang ◽  
Eun-Cheol Park ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Function ◽  
Handgrip Strength ◽  
Panel Study ◽  
Continuous Variable ◽  
South Korean ◽  
Korean Adults ◽  
Strength Change ◽  
The Relationship ◽  
State Examination

Abstract Background Muscular function, such as handgrip strength, has been suggested as an associated factor for cognitive impairment. This study investigated the association between temporal change in handgrip strength and cognitive function using longitudinal, nationwide data from Korean older adults. Methods Our study used data from the Korean Longitudinal Study of Aging (KLoSA). The analysis covered 6696 participants who had taken the handgrip strength test and Mini-Mental State Examination (MMSE) from 2006 to 2018. We adopted general estimating equations to assess the temporal effect of handgrip strength change on cognitive function. Results After adjusting for covariates, we observed an association between handgrip strength and low MMSE scores (β = − 0.3142 in men, β = − 0.2685 in women). Handgrip strength as a continuous variable was positively correlated with MMSE scores after adjustment (β = 0.0293 in men, β = 0.0347 in women). The group with decreased handgrip strength over time also showed greater odds for mild cognitive impairment (OR = 1.23, 95%CI = 1.05–1.27 in men, OR = 1.15, 95%CI = 1.05–1.27 in women) and dementia (OR = 1.393, 95%CI = 1.18–1.65 in men, OR = 1.19, 95%CI = 1.08–1.32 in women). Conclusions This study identified the relationship between handgrip strength change and cognitive function among South Korean adults. According to our large, longitudinal sample, decreasing handgrip strength was associated with decline in cognitive function.

scholarly journals Characteristics of Acute Myocardial Infarction Patients

2020 ◽  
Vol 9 (2) ◽  
pp. 1017-1026
Author(s):  
Desi Natalia Trijayanti Idris ◽  
Dian Taviyanda ◽  
Srinalesti Mahanani
Keyword(s):  
Diabetes Mellitus ◽  
Myocardial Infarction ◽  
Blood Pressure ◽  
Acute Myocardial Infarction ◽  
Family History ◽  
Frequency Distribution ◽  
Pulse Frequency ◽  
Education History ◽  
Male And Female ◽  
History Of

Acute myocardial infarction (AMI) is a disease that has a high mortality. Usually happens to anyone and regardless of age, both male and female. The purpose of this study was to describe the characteristics of acute myocardial infarction patients hospitalized. This study uses a descriptive design. The variables used in this study were the characteristics of acute myocardial infarction patients consisting of gender, age, education, history of hypertension, history of diabetes mellitus, family history of acute myocardial infarction, blood pressure and pulse frequency. The number of samples used was 35 respondents who analyzed the data using a frequency distribution. The results showed that the characteristics of 35 respondents showed that the majority of AMI patients occurred in men, namely 60%, the majority were aged 56-60, namely 34.3%, the majority had a history of hypertension, diabetes mellitus and also a family history of having AMI. 

scholarly journals The relationship between serum hepatitis B core-related antigen and hepatitis B virus DNA in treatment-naïve patients with hepatitis B cirrhosis: A cross-sectional study

2021 ◽  
Author(s):  
Baiguo Xu ◽  
Lian Jia ◽  
Anjing Liu ◽  
Ying Liu ◽  
Tao Han ◽  
...  
Keyword(s):  
Family History ◽  
Hepatitis B ◽  
Hbv Dna ◽  
Hepatic Carcinoma ◽  
Primary Hepatic Carcinoma ◽  
B Virus ◽  
Treatment Naïve ◽  
History Of ◽  
Pugh Class ◽  
The Relationship

Abstract Aims. The relationship between hepatitis B core-related antigen (HBcrAg) and hepatitis B virus (HBV) DNA has already been adequately researched in patients with chronic hepatitis B (CHB) infection, but there are only a few researches yet on the correlations between HBcrAg and HBV DNA in treatment-naïve patients with hepatitis B cirrhosis. Here we explore the correlation between HBcrAg and HBV DNA in this population. Methods. Available data and samples of 98 untreated patients with hepatitis B cirrhosis between October 2018 and October 2019 were analysed. Statistical analyses included baseline characteristics, univariate analysis, stratification analysis, three different analytical models, and a generalized additive model. Results. After adjusting for all recorded confounders (sex, age, diagnosis of primary hepatic carcinoma, total bilirubin（TBIL）, hepatitis B surface antigen (HBsAg), hepatitis B e antigen(HBeAg), Child–Pugh class, family history of HBV infection, family history of hepatocellular carcinoma(HCC), alcohol-related liver disease (ALD), and diabetes mellitus), a linear relationship was detected between HBcrAg and HBV DNA (β=0.59, 95%CI=0.34–0.84, P<0.0001). The variational trend of HBcrAg and HBV DNA in each stratified variable (sex, age, HBeAg, family history of HBV infection, family history of HCC, diabetes mellitus, diagnosis of primary hepatic carcinoma, Child–Pugh class, and ALD) were consistent. Conclusion. There was a linear and positive correlation between HBcrAg and HBV DNA in treatment-naïve patients with hepatitis B cirrhosis.

632 Family History of Children Diagnosed with Obstructive Sleep Apnea

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A248-A248
Author(s):  
Kristi Porterfield-Pruss ◽  
Denise Willis ◽  
Beverly Spray ◽  
Supriya Jambhekar
Keyword(s):  
Family History ◽  
Family Members ◽  
Biological Father ◽  
Medical Problems ◽  
Obstructive Sleep ◽  
Familial Association ◽  
History Of ◽  
The Mean ◽  
Relationship Of ◽  
The Relationship

Abstract Introduction Limited evidence suggests a familial association of OSA. It is not known how often children who require positive airway pressure (PAP) devices have a family member with OSA or that requires PAP. It is felt that PAP adherence in children is affected by PAP adherence in parents. We wanted to explore the relationship of OSA in children requiring PAP to OSA in immediate family members as well as the association of obesity and adherence between children and family members. Methods Caregivers of children who utilize PAP devices at home were invited to complete an electronic questionnaire regarding family history of OSA. Descriptive statistics were utilized to summarize results. Results The study was completed by 75 participants. The majority of children were male (64%, 48/75), black (47%, 35/75) and non-Hispanic (88%, 66/75). The mean age was 11.8 years (median 13) and mean BMI was 32.8 (median 29.8). The mean AHI on the diagnostic polysomnogram was 28.4 events per hour (median 15.3). Mean adherence to PAP &gt; 4 hours per night was 56.5 (Median 68.2). Most, 87% (65/75), have other underlying medical problems. Twenty-four percent (18/75) have a biological father with OSA of whom 61% (11/18) are considered moderately/extremely obese. Of mothers, 13% (10/75) have OSA and 70% (7/10) are obese. Overall, 29% (22/75) had either a paternal (11%, 8/75) or maternal (19%, 14/75) grandfather with OSA of which 36% (8/22) are obese. For grandmothers, 31% (23/75) have OSA and 22% (5/23) are obese with more being paternal (19%, 14/75) compared to maternal (12%, 9/75). Of the 73 total family members reported to have OSA, 86% (63/73) use PAP and most (65%, 41/63) use it for &gt; 4 hours every night. Few participants had siblings with OSA. Conclusion There were more fathers with OSA than mothers, but mothers were reported to be obese more often. Grandparents were reported to have OSA but were reported to be obese less often than parents. Maternal grandparents with OSA were reported to be obese more than paternal grandparents. The majority of family members with OSA who use CPAP report nightly use. Support (if any):

scholarly journals The Relationship between Chronotype, Physical Activity and the Estimated Risk of Dementia in Community-Dwelling Older Adults

2020 ◽  
Vol 17 (10) ◽  
pp. 3701
Author(s):  
Ngeemasara Thapa ◽  
Boram Kim ◽  
Ja-Gyeong Yang ◽  
Hye-Jin Park ◽  
Minwoo Jang ◽  
...  
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Mental State ◽  
Mini Mental State Examination ◽  
Community Dwelling ◽  
Daily Physical Activity ◽  
Estimated Risk ◽  
Community Dwelling Older Adults ◽  
The Relationship ◽  
State Examination

Our study examined the association between chronotype, daily physical activity, and the estimated risk of dementia in 170 community-dwelling older adults. Chronotype was assessed with the Horne–Östberg Morningness–Eveningness Questionnaire (MEQ). Daily physical activity (of over 3 METs) was measured with a tri-axial accelerometer. The Korean version of the Mini-Mental State Examination (K-MMSE) was used to measure the estimated risk of dementia. The evening chronotype, low daily physical activity, and dementia were positively associated with each other. The participants with low physical activity alongside evening preference had 3.05 to 3.67 times higher estimated risk of developing dementia, and participants with low physical activity and morning preference had 1.95 to 2.26 times higher estimated risk than those with high physical activity and morning preference. Our study design does not infer causation. Nevertheless, our findings suggest that chronotype and daily physical activity are predictors of the risk of having dementia in older adults aged 70 years and above.

scholarly journals The Relationship between Hypertension and Cognitive Function Impairment in the Elderly

2019 ◽  
Vol 7 (9) ◽  
pp. 1440-1445 ◽  
Author(s):  
Endy Juli Anto ◽  
Laura Oktavina Siagian ◽  
Jekson Martiar Siahaan ◽  
Hendrika Andriana Silitonga ◽  
Sony Eka Nugraha
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Function ◽  
Nursing Homes ◽  
Significant Relationship ◽  
The Elderly ◽  
Research Approach ◽  
Impaired Cognitive Function ◽  
Function Impairment ◽  
The Relationship ◽  
Second Degree

BACKGROUND: Hypertension is still a health problem both in developed and developing countries. Hypertension can cause various complications; one of them is cognitive function impairment. AIM: This study aimed to look at the relationship of hypertension with cognitive function. This research can also be useful to help optimise the health of the elderly, maximise quality of life and avoid hypertension as a risk factor for cognitive impairment in the elderly at the Karya Kasih Nursing Homes, Medan from May to June 2018. METHODS: This research was carried out by analytic observational with cross-sectional research approach. In this study, 57 elderly from Karya Kasih Nursing Homes Medan who met the inclusion and exclusion criteria participated. Assessment of cognitive function used Mini-Mental State Examination (MMSE), Six Item Cognitive Impairment Test (6CIT) and Abbreviated Mental Test Score (AMT) instruments. RESULT: This study obtained a significant relationship between the history of hypertension with impaired cognitive function (p = 0.003). The results of the cognitive function examination with MMSE showed that among 57 elderly, 16 people (43.2%) were normal and 21 people (56.8%) had impaired cognitive function in the first degree hypertension group, besides that, 3 people were normal (15%) and 7 people (85%) had impaired cognitive function in the second degree hypertension group (p = 0.031). Based on the result of mild and severe cognitive function impairment, among 12 people (57.1%) and 9 people (42.9%) had a mild and severe cognitive function impairment, respectively, in first-degree hypertension. 3 people (17.6%) and 14 people (82.4%) had a mild and severe cognitive function impairment, respectively, in the second-degree hypertension (p = 0.013). The 6-CIT instrument also showed a significant relationship between the severity of hypertension and impaired cognitive function (p = 0.027), and there was no significant relationship with AMT instruments (p = 0.078). CONCLUSION: There was a relationship between the history or duration and degree of hypertension with cognitive dysfunction in the elderly at the Karya Kasih Nursing Home Medan.

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