scholarly journals Oral and Dental Considerations in Pediatric Leukemic Patient

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Chiyadu Padmini ◽  
K. Yellamma Bai
Keyword(s):  
Quality Of Life ◽  
Mortality Rate ◽  
Early Diagnosis ◽  
Cancer Treatment ◽  
Dental Care ◽  
Pediatric Dentist ◽  
The World ◽  
Oncology Treatment

Throughout the world, there have been drastic decline in mortality rate in pediatric leukemic population due to early diagnosis and improvements in oncology treatment. The pediatric dentist plays an important role in the prevention, stabilization, and treatment of oral and dental problems that can compromise the child’s health and quality of life during, and follow up of the cancer treatment. This manuscript discusses recommendations and promotes dental care of the pediatric leukemic patients.

scholarly journals Endoscopy of Nasopharyngeal Cancer

1994 ◽  
Vol 1 (2) ◽  
pp. 63-68 ◽  
Author(s):  
Brian B. Burkey ◽  
Robert H. Ossoff
Keyword(s):  
Quality Of Life ◽  
High Risk ◽  
High Resolution ◽  
Local Anesthesia ◽  
Nasopharyngeal Cancer ◽  
Cost Effective ◽  
Cost Effective Approach ◽  
The World

Nasopharyngeal cancer (NPC) is a unique disease with increasing interest for many physicians due to its unusual etiology, histology, and epidemiology. The recent era of fiberoptic endoscopy now provides the clinician with better tools for the screening, diagnosis, staging, and follow-up of NPC. The use of high resolution flexible and rigid nasopharyngoscopy gives the physician an opportunity for a more sensitive examination in a higher proportion of patients. Ultimately, this will allow for earlier diagnosis of NPC, and improved prognosis and better quality of life for the patients with this disease. Also, by allowing the clinician to perform directed biopsies of the nasopharynx under local anesthesia, fiberoptic nasopharyngoscopy allows a less morbid and more cost-effective approach towards this disease, including screening protocols in certain high risk regions of the world.

scholarly journals A prospective study of demographic features and quality of life in HIV-positive women with cervical cancer treated at Tygerberg Hospital

2015 ◽  
Vol 16 (1) ◽  
Author(s):  
George Du Toit ◽  
Martin Kidd
Keyword(s):  
Quality Of Life ◽  
Cervical Cancer ◽  
Cancer Treatment ◽  
Hiv Positive ◽  
Hiv Positive Women ◽  
Eortc Qlq C30 ◽  
Eortc Qlq ◽  
Hiv Negative

Background: Cervical cancer and human immunodeficiency virus (HIV) infection/acquired immune deficiency syndrome (AIDS) both have a high incidence in South Africa. Cervical cancer treatment of HIV-positive women poses challenges. Treatment-related changes in quality of life (QOL) of such women are important to future treatment protocols.Aim: To examine demographic data of HIV-negative and HIV-positive women at diagnosis of cervical cancer and describe their changes in QOL as a result of treatment.Methods and materials: All newly diagnosed patients with cervical cancer at Tygerberg Hospital were approached to participate in the study. The European Organisation for Research and Treatment of Cancer Quality of Life Core Questionnaire (EORTC QLQ-C30) and the Cervix Cancer Module (QLQ-CX24) were used. General QOL was measured with the EORTC QLQ-C30 and cervical-specific QOL with the QLQ-CX24 questionnaire. The patients completed the questionnaire at diagnosis, on completion of treatment and at 3 months’ follow-up.Results: The study included a total of 221 women of whom 22% were HIV-positive; the latter were younger and of higher educational level than the rest. Mean monthly income and stage distribution was similar between the two groups. HIV-positive patients underwent radiation therapy more commonly than chemoradiation. HIV-positive women showed statistically significantly higher loss to follow-up during the study. HIV-positive women experienced no improvement in insomnia, appetite loss, nausea, vomiting, diarrhoea, social role or any of the sexual domains. In contrast, HIV-negative women experienced statistically significant improvement in all sexual domains other than sexual/vaginal functioning. The QOL improvement of HIV-negative women was statistically significantly greater than their HIV-positive counterparts in the majority of QOL domains. Global health improved in both groups, with HIV-negative women experiencing greater improvement. HIV-positive women experienced an initial decline of peripheral neuropathy (PN) symptoms post treatment with a return to pretreatment values at 3 months’ follow-up. The change in PN was statistically significant between the HIV-negative and HIV-positive women.Conclusion: Demographic differences exist between the HIV-negative and HIV-positive groups. The differential outcome in the QOL of HIV-positive and HIV-negative women treated for cervical cancer might be related to persistence of AIDS-related symptoms on completion of cervical cancer treatment.

scholarly journals A Study to Assess the Quality of Life of Postoperative Patients With Oral Cancer in B.R.A I.R.C.H., AIIMS, New Delhi

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 100s-100s
Author(s):  
N. Paulose ◽  
A. Sinha ◽  
S.V.S. Deo
Keyword(s):  
Quality Of Life ◽  
Weight Loss ◽  
Oral Cancer ◽  
Hospital Stay ◽  
Head And Neck ◽  
New Delhi ◽  
The World ◽  
Speech Problem

Introduction: Cancer is a leading cause of death in both developed and underdeveloped countries in the world. The Indian subcontinent accounts for one-third of the world burden of head and neck cancer. Surgery is the standard treatment of choice for head and neck cancers. It is imperative to give supportive care to improve the quality of life. Aim: To assess the quality of life of postoperative patients with oral cancer in B.R.A I.R.C.H, AIIMS, New Delhi. Methodology: The study was conducted at B.R.A.I.R.C.H, AIIMS, New Delhi. The data were collected by convenience sampling from 50 adults who underwent surgery for oral during June 2017 to December 2017. Standardized self-structured EORTC QOL(H&N) was used to assess the perceived level of the quality of life of postoperative patients with oral cancer during hospital stay and at one month follow-up. Ethical clearance was obtained from institutional ethics committee. Results: 80% patients were male. Majority of the patients underwent mandibulectomy (66%) modified neck dissection (60%) and regional flap reconstruction (56%). The major symptoms perceived during hospital stay were pain (98%), speech problem (84%), problem in opening mouth (82%), felt ill (80%), weight loss (74%), etc. and at one month follow-up were problem in opening mouth (90.6%), pain (90.5%), speech problem (83.6%), weight loss (82%), among many others. There was a significant decrease in the perceived pain (11.2 ± 2.99) at one month follow-up (9.12 ± 3.42). Conclusion: Most of the patients experience pain, problem in opening mouth, sticky saliva, speech problem, trouble in social contact, weight loss, etc.

scholarly journals A new paradigm of screening and early diagnosis: assessment of benefits and harms

2020 ◽  
Vol 66 (6) ◽  
pp. 589-602
Author(s):  
Давид Заридзе ◽  
Dmitry Maksimovich ◽  
Ivan Stilidi
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Prostate Cancer ◽  
Clinical Trials ◽  
Early Diagnosis ◽  
The United States ◽  
Diagnostic Methods ◽  
New Paradigm

Abstract The article presents scientific evidence that confirms the new paradigm that  “early” diagnosis is not always beneficial, and that screening and early diagnosis can do more harm than good. As a result, of screening, in a number of cases, lesions are diagnosed that, although have histological patterns of cancer, are often clinically insignificant, indolent i.e. overdiagnosis takes place. Such lesions primarily include latent cancers of the prostate and thyroid gland. An increase in the incidence of certain types of cancers in the United States and other developed countries, as a result, of the introduction of PSA screening, mammography, ultrasound examination of the neck and other highly sensitive diagnostic methods, with stable or decreasing mortality, is a sign of overdiagnosis. In Russia, there is also a marked increase in the incidence of cancer of the prostate, breast, thyroid, kidney and melanoma, while mortality from these forms of cancer is stable or decreasing. The increase in the incidence of all malignant formations in Russian, as in American men, is determined by the increase in the incidence of prostate cancer. In randomized clinical trials of the efficacy of screening for prostate and breast cancer, an excess of the detected cases of cancer in the screening group compared with the control group indicates overdiagnosis. With an increase in follow-up (10-15 years), the number of excess cases in the screening group decreases. However, in some studies even after 10-15 years of follow-up, the excess of cancer cases in the screening group persisted, i.e. overdiagnosis was confirmed. Thus, the problem of overdiagnosis is also relevant to controlled clinical trials, despite a well-verified protocol and strict adherence to it. The danger of overdiagnosis in real life, daily practice, and especially with opportunistic screening, which, by definition, is carried out without quality control, is much higher. Overdiagnosis often leads to unnecessary, sometimes excessive treatment and a deterioration in the quality of life of patients who are not cancer patients. Refusal of aggressive therapy and active follow-up should be the method of choice for the management of patients with asymptomatic neoplasms identified at the screening. Such tactics will avoid unnecessary and excessive interventions, which, in turn, will prevent a deterioration in the quality of life of patients and, in addition, will reduce the cost of treatment. Key words: overdiagnosis, screening, early diagnosis, trends in incidence and mortality, prostate cancer, breast cancer, thyroid cancer

scholarly journals Daganatos betegekben kialakult másodlagos nyiroködéma ellátása

2016 ◽  
Vol 157 (13) ◽  
pp. 488-494
Author(s):  
Enikő Wenczl
Keyword(s):  
Quality Of Life ◽  
Chronic Disease ◽  
Early Diagnosis ◽  
Cancer Patients ◽  
Life Style ◽  
Healthcare Costs ◽  
Weight Control ◽  
Oncological Patients

Due to the increased number of cancer patients and the progress in cancer treatment, there are more cases with cancer-related lymphedema. Lymphedema treatment became part of oncological patients’ care. Basic therapy for lymphedema is the complex decongestive therapy, which should be embedded into the patient’s comprehensive medical care and should always be determined individually. Results of therapy are influenced by the experience of the doctor and the physiotherapist in lymphedema care, patient’s complience, tumor behavior and the accompanying diseases. Lymphedema is a chronic disease, requires lifelong follow-up and treatment. For prevention and better care, it would be important to inform patients about lymphedema risk and appropriate life-style (e.g. weight control) preoperatively and during oncological follow-up. Early diagnosis is important. Lymphedema treatment should be integrated into palliative programmes. If therapy is started in time, complications may be avoided, healthcare costs may be reduced and better quality of life may be achieved. Orv. Hetil., 2016, 157(13), 488–494.

Clinical Diagnostication Requirements for Diabetes

2020 ◽  
pp. 8-15
Author(s):  
Vladimir Klimov
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Mortality Rate ◽  
Vascular Complications ◽  
Modern Medicine ◽  
Late Complications ◽  
The World ◽  
Medicine Today ◽  
Diagnosis Of Diabetes Mellitus

Diabetes is one of the most pressing problems of modern medicine. Today, there are 150 million people with diabetes in the world; by 2025 this number is expected to reach 300 million. Diabetes mellitus is one of the significant causes of early disability and death due to late vascular complications owing to macroangiopathy, microangiopathy and neuropathy. Timely diagnosis of diabetes mellitus, prevention of the development of its early and late complications can significantly reduce the mortality rate for this pathology, improve the quality of life of patients and prevent formidable complications.

Quality of life and sexual functioning after cervical cancer treatment: a long-term follow-up study

2009 ◽  
Vol 18 (5) ◽  
pp. 476-482 ◽  
Author(s):  
Elfriede R. Greimel ◽  
Raimund Winter ◽  
Karin S. Kapp ◽  
Josef Haas
Keyword(s):  
Quality Of Life ◽  
Cervical Cancer ◽  
Cancer Treatment ◽  
Sexual Functioning ◽  
Follow Up Study ◽  
Long Term Follow Up

scholarly journals Attention to bone health in follow-up of gynaecological cancers in tertiary care

2022 ◽  
Vol 18 ◽  
pp. 174550652110707
Author(s):  
Catherine A O’Gorman ◽  
Sorcha Minnock ◽  
Joseph Mulhall ◽  
Noreen Gleeson
Keyword(s):  
Quality Of Life ◽  
Bone Loss ◽  
Cancer Treatment ◽  
Bone Health ◽  
Gynaecological Cancer ◽  
Mineral Density ◽  
Care Gap ◽  
Risk Of Cancer

Objective: Women with gynaecological cancers are at an increased risk of cancer treatment–induced bone loss, which impacts on their quality of life and overall survival. Clinical cancer follow-up reviews focus on cancer status and fail to attend to important health and quality-of-life issues. We questioned whether there was a care-gap between tertiary clinicians and primary care physicians in the management of bone health in this cohort. Significant care-gaps in relation to bone health have been demonstrated in other oncologic settings. The objective of this study was to determine the level of attention to bone health in the care of women living with and beyond gynaecological cancer at a tertiary referral centre for gynaecological oncology. Methods: Retrospective, observational cohort study of attention to bone health in the management and follow-up of gynaecological cancers. Results: This study shows that there has been suboptimal attention from the carers at a cancer centre to bone health during the oncological follow up of women undergoing treatment for gynaecological cancer. In those at particular risk of cancer treatment–induced bone loss (iatrogenic menopause and/or external beam pelvic radiotherapy), 52% of women had no reference to bone health in their notes, and 57% had no assessment of bone mineral density. Conclusion: Tertiary cancer carers may underestimate the importance of bone health or believe that it falls outside the remit of their gynaecologic oncology service. Further research is needed to explore whether these findings are indicative of a true care gap and to gain insight into possible corrective measures.

scholarly journals Dermoscopic findings in female androgenetic alopecia

2012 ◽  
Vol 87 (5) ◽  
pp. 691-694 ◽  
Author(s):  
Lya Duarte Ramos ◽  
Maria Cândida Nahás Santili ◽  
Fabiane Castilho Bezerra ◽  
Maria de Fátima Maklouf Amorim Ruiz ◽  
Valeria Petri ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Early Diagnosis ◽  
Therapeutic Response ◽  
Digital Camera ◽  
Self Esteem ◽  
Daily Basis ◽  
Androgenetic Alopecia ◽  
Excellent Tool

BACKGROUND: Androgenetic alopecia is the most common form of hair loss. It is a clinical entity of relevant interest and presents a significant psychosocial impact as it undermines self-esteem and quality of life in female patients due to the importance of the hair for people's facial balance. OBJECTIVE: The purpose of the present study is to evaluate dermoscopic signs in women clinically diagnosed with androgenetic alopecia. METHOD: Observational study with 34 women between 17 and 68 years old who were diagnosed with androgenetic alopecia. All of them underwent photographic sessions with a 10x magnification dermoscope and a digital camera zoom set to 20x magnification and 40x magnification on the scalp frontal midline. RESULTS: All patients showed miniaturization. A peripilar brown halo was found in 22 patients, honeycomb-like scalp pigmentation was found in 14 and yellow dots in only 1 patient. Recent studies show dermoscopy as the new tool for diagnosis assistance and treatment follow up in scalp disorders. Our study used an ordinary dermoscope and we evaluated several findings reported in the literature with significant clarity and easiness. CONCLUSION: The dermoscope, which is used by dermatologists on a daily basis, is an excellent tool to assist in early diagnosis and assessment of therapeutic response in androgenetic alopecia.

Occhio all’asimmetria toracica alla nascita... e se fosse la sindrome di Poland?

2021 ◽  
Vol 24 (6) ◽  
pp. 166-170
Author(s):  
Antonella Di Caprio ◽  
Luca Bedetti ◽  
Simona F. Madeo ◽  
Laura Lucaccioni ◽  
Federica Roversi ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Case Report ◽  
Early Diagnosis ◽  
Pectoralis Major Muscle ◽  
Poland Syndrome ◽  
Therapeutic Approaches ◽  
Limb Defects ◽  
Rare Congenital Disorder

Poland syndrome is a rare congenital disorder characterized by agenesis of the pectoralis major muscle. It is usually unilateral and right-sided and can be associated with several thoracic and upper limb defects. Early diagnosis and timely therapeutic approaches play an important role, improving the quality of life of patients and their families. This case report aims to show the benefits of early diagnosis, especially for follow-up management.

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