scholarly journals Association of ABO Blood Group Phenotype and Allele Frequency with Chikungunya Fever

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Pairaya Rujirojindakul ◽  
Virasakdi Chongsuvivatwong ◽  
Pornprot Limprasert
Keyword(s):  
Allele Frequency ◽  
Blood Group ◽  
Rural Community ◽  
Statistical Significance ◽  
Community Survey ◽  
Abo Blood Group ◽  
Chi Square ◽  
Southern Thailand ◽  
Chi Square Test ◽  
Group Allele

Background. The objective of this study was to investigate the association of the ABO blood group phenotype and allele frequency with CHIK fever.Methods. A rural community survey in Southern Thailand was conducted in August and September 2010. A total of 506 villagers were enrolled. Cases were defined as individuals having anti-CHIK IgG by hemagglutination ≥1 : 10.Results. There were 314 cases (62.1%) with CHIK seropositivity. Females were less likely to have positive anti-CHIK IgG with odds ratio (OR) (95% CI) of 0.63 (0.43, 0.93). All samples tested were Rh positive. Distribution of CHIK seropositivity versus seronegativity (Pvalue) in A, B, AB, and O blood groups was 80 versus 46 (0.003), 80 versus 48 (0.005), 24 versus 20 (0.55), and 130 versus 78 (<0.001), respectively. However, chi-square test between ABO and CHIK infection showed no statistical significanceP=0.76. Comparison of the ABO blood group allele frequency between CHIK seropositivity and seronegativity was not statistically significant.Conclusion. This finding demonstrated no association of the ABO blood group phenotypes and allele frequencies with CHIK infection.

scholarly journals GENOTYPE AND ABO BLOOD GROUP ASSOCIATION WITH PREVALENCE OF MALARIA AMONG PATIENTS IN UNIVERSITY OF NIGERIA MEDICAL CENTER: A CROSS-SECTIONAL EVALUATION

2019 ◽  
pp. 28-32
Author(s):  
Abdulmuminu Isah ◽  
Chibueze Anosike ◽  
Chukwuma Stephen Ogbodo ◽  
Charles Obinna Emeka ◽  
Chukwuemeka Sylvester Nworu
Keyword(s):  
Blood Group ◽  
Medical Center ◽  
Pearson Correlation ◽  
Statistical Significance ◽  
Malaria Prevalence ◽  
Abo Blood Group ◽  
Chi Square ◽  
Cross Sectional ◽  
The Difference ◽  
Cross Sectional Design

Objective: The aim of this study was to evaluate the prevalence of malaria and its relationship with the ABO blood group and genotype at the University of Nigeria Medical Centre. Methods: The study had a prospective cross-sectional design in which malaria status and blood groups and genotype were determined. All collected data were analysed using Statistical product and services Solution (V.21). Frequencies and percentages were used to describe the data while Chi-square and Pearson correlation were used to determine associations between malaria prevalence and patients’ demographic and clinical characteristics. Statistical significance was considered for p<0.05. Results: Three hundred and twenty-three (323) patients were tested for malaria, 245(75.9%) of whom tested positive. The prevalence was highest for patient’s aged 19-25 y (28.5%). The difference was statistically significant for age: χ2 (5) = 33.60, p = 0.0005. There were more blood group O (57.6%) among the patients, while AA genotype was the majority (72.4%). Those with blood group O had the highest prevalence of malaria (33.7%) and it was statistically significant (χ2 (3) = 72.10, p = 0.0005)). Correlation showed that the association between blood group and malaria prevalence was moderate (R = 0.457). The AA genotype had more incidence of malaria (54.5%), but the difference was not statistically significant. Conclusion: The prevalence of malaria was high among the patients surveyed. Its association with the patients’ ABO blood group was established to be statistically significant, with blood group O having the highest incidence. Although AA genotype was observed to have the highest cases of malaria, the relationship was found not to be significant.

scholarly journals A Study on Otorhinolaryngological Presentations in Covid 19 Patients in a Tertiary Health Care Center

2021 ◽  
Author(s):  
S. G. Smitha ◽  
Nikitha Pillai ◽  
Bindya Nayak ◽  
Jedhin Raveendran
Keyword(s):  
Blood Group ◽  
Rna Virus ◽  
Statistical Significance ◽  
Care Center ◽  
Chi Square ◽  
Health Care Center ◽  
Corona Virus ◽  
Chi Square Test ◽  
The Relationship ◽  
Written Informed Consent

AbstractCorona virus also known as 2019 novel corona virus, a single stranded positive sense RNA virus is the causative agent of COVID 19 disease. It mainly spreads via the respiratory route by means of aerosols. The objectives of our study were. To know the prevalence of ENT presentations in COVID 19 patients and to know the relationship between the symptoms and category of the disease as well as to know the relation between the blood group and recovery from the disease. The first 500 patients who were tested positive for COVID 19 and getting treated in our hospital were included in the study after taking written informed consent from the patients who were willing to participate in the study. A detailed history was taken from all the patients and more stress was given on the ENT symptoms with respect to its onset, duration and time taken for the relief of symptoms. The ENT symptoms were compared with the category of the disease as well as the blood group of the patients. Statistical analysis was done using Chi square test and Statistical Package for Social Sciences [SPSS] for Windows Version 22.0 Released 2013. Armonk, NY: IBM Corp., was used to perform statistical analyses. In our study 310 (62.0%) were males and 190 (38.0%) patients were females (38%), of age group ranging from 2 years to 87 years. In our study 367 (73.3%) patients were symptomatic and the rest 133 (26.6%) were asymptomatic. There were 335 (67.0%) patients in category A, 140 (28.0%) in category B and 25 (5.0%) in category C. The most common ENT presentation was headache and its prevelance was more in category C and it was of statistical significance. On comparing the blood group and the ENT symptoms occurrence of sore throat was of statistical significance and its prevelance was more among the O blood group patients. In terms of recovery from the disease the patients with blood group O had good recovery rate. Covid 19 pandemic is still an on going problem and newer strains of the virus are arising as well hence. In our study we found out that isolated ENT symptoms such as aguesia and anosmia were the only presentation of the disease. Thus they can be considered as early marker of the disease and it will be helpful in early detection and isolation of the patient as well as prevention of further spread of the disease.

scholarly journals ABO Blood Group. Related Investigations and Their Association with Defined Pathologies

2007 ◽  
Vol 7 ◽  
pp. 1151-1154 ◽  
Author(s):  
Ursula Jesch ◽  
P. Christian Endler ◽  
Beatrix Wulkersdorfer ◽  
Heinz Spranger
Keyword(s):  
Blood Group ◽  
Abo Blood Group ◽  
Blood Group System ◽  
Chi Square ◽  
Ulcus Ventriculi ◽  
Group System ◽  
Blood Group A ◽  
Chi Square Test ◽  
Group A ◽  
Group Sex

The ABO blood group system was discovered by Karl Landsteiner in 1901. Since then, scientists have speculated on an association between different pathologies and the ABO blood group system. The aim of this pilot study was to determine the significance between different blood types of the ABO blood group system and certain pathologies. We included 237 patients with known diagnosis, blood group, sex, and age in the study. As a statistical method, the Chi-square test was chosen. In some cases, a significant association between the blood groups and defined diseases could be determined. Carriers of blood group O suffered from ulcus ventriculi and gastritis (X21 = 78.629, p <0.001), colitis ulcerosa and duodenitis (X21 = 5.846, p < 0.016), whereas male patients carrying blood group A tended to contract different types of tumours. In patients with intestinal tumours, females with blood group A were more likely to develop the pathology, whereas in males, the blood group O dominated. The development of cholelithiasis was found, above all, in patients with blood group O, which differed from other research where a correlation between this pathology and blood group A was found.

scholarly journals Genotypic and Alelicas Frequencies of the ABO and Rh Systems in the State of Rio Grande Do Norte, Northeast of Brazil

Blood ◽  
2019 ◽  
Vol 134 (Supplement_1) ◽  
pp. 4990-4990
Author(s):  
Linduarte Varela Morais ◽  
Aldair Sousa Paiva ◽  
Valéria SF Sales ◽  
Geraldo Barroso Cavalcanti
Keyword(s):  
Blood Group ◽  
Blood Donors ◽  
Conflicts Of Interest ◽  
Statistical Significance ◽  
Cross Sectional Study ◽  
Blood Group Antigens ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Group B

Objective: To determine the immunophenotyping of a population of blood donors, intended to build a database for transfusion medicine. 2) To make available to patients with chronic diseases that are systematically dependent on blood transfusions as compatible as possible in ABH, Rh (DCcEe) and Kell 1 antigen systems. Method: A cross-sectional study was carried out on 11,664 blood donors for the ABH system typing and of these, 1255 blood donors were selected randomly for the determination of blood group antigens of the Rh system and Kell antigen. Blood centrifugation methods, centrifuge hemolysis tube test and indirect Coombs test were used for blood typing. The results obtained were compared by the Chi-square test. A level of statistical significance of p ≤ 0.05 was considered. Results: Antigenic frequencies for the ABH system found: the frequency found for the blood group O 48.8%, the frequency found for the blood group A 35.4%; the frequency found for the blood group B 10.6% and the frequency found for the blood group AB 3.2%. In the Rh-Hr system the most frequent antigens found: e 94.5%, D 88.9%; c 80.6; C 56.4%; E 26.3%. For the Kell antigen, the frequency found was 6.7%. The most frequent phenotypes found were DCcee 23.3%; ddccee 18.1%, DCCee 16.7%; Dccee 11.0%; DCcEe 10.2% and DccEe 8.8%. The lowest frequency was found: DCcEE 0.64% and ddCcEe 0.08% Conclusion: The antigenic and phenotypic frequencies found show the great importance and necessity of the immunophenotyping of these antigens of blood groups in order to transfuse them, making them as compatible as possible, thus reducing the risk of alloimmunization. Due to the great miscegenation of our population, we find different frequencies in each region, making initiatives in this regard more relevant. Disclosures No relevant conflicts of interest to declare.

scholarly journals The effect of improved housing on indoor mosquito density and exposure to malaria in the rural community of Minkoameyos, Centre Region of Cameroon.

2019 ◽  
Author(s):  
Rachel Laure Nguela ◽  
Jude D. Bigoga ◽  
Tedjou N. Armel ◽  
Tallah Tayie Ngobiyo Esther ◽  
Line Leukou Dongmo ◽  
...  
Keyword(s):  
Rural Community ◽  
Statistical Significance ◽  
Malaria Prevalence ◽  
Reduction Factor ◽  
Mosquito Density ◽  
Insecticide Treated Nets ◽  
Chi Square ◽  
Factors Affecting ◽  
Centre Region ◽  
Chi Square Test

Abstract Background: Malaria control faces several threats. Alternative strategies to complement Long Lasting Insecticide-treated Nets and antimalarial therapy are therefore mandatory. This study evaluated the effectiveness of improved housing on indoor residual mosquito density and exposure to malaria-carrying Anophelines in Minkoameyos, a rural community in the center region of Cameroon.Methods: Following the identification of housing factors affecting malaria prevalence in 2013, 218 houses were improved (screening of doors and windows, installing plywood ceilings on open eaves, closing holes on the walls and doors). Quarterly surveys were conducted in a sample of 21 improved and 21 non-improved houses from November 2014 to October 2015. Mosquitoes sampled by night collections on human volunteers were identified morphologically. Their parity status determined. Mosquito infectivity was verified through Plasmodium falciparum CSP ELISA. The average entomological inoculation rates were determined. A Reduction Factor (RF), defined as the ratio of the values for mosquitoes collected outdoor to those collected indoor was calculated in improved houses (RFI) and non-improved houses (RFN). An Intervention Effect (IE=RFI/RFU) measured the true effect of the intervention. Chi-square test was used to determine variable significance. The threshold for statistical significance was set at P < 0.05.Results: A total of 1113 mosquitoes were collected comprising: Anopheles (58.6%), Culex (36.4%), Aedes (2.5%), Mansonia (2.4%) and Coquillettidia (0.2%). Amongst the anophelines were An. gambiae s.l. (95.2%), An. funestus (2.9%), An. ziemanni (0.2%), An. brohieri (1.2%) and An. paludis (0.5%). An gambiae s.s. was the only Anopheles gambiae sibling found. The intervention reduced the indoor Anopheles density by 1.8 fold (RFI=3.99; RFN=2.21; P=0.001 ). The indoor density of parous Anopheles was reduced by 1.7 fold (RFI=3.99; RFN=2.21; P=0.04 ) and that of infected Anopheles by 1.8 fold (RFI=3.26; RFN=1.78; P=0.04 ). Indoor peak biting rates were observed between 02am to 04am in non improved houses and from 02am to 06am in improved houses.Conclusion: Housing improvement reduced indoor residual anopheline density and malaria transmission. This highlights the need for Standardization and promotion of similar interventions to prevent malaria in comparable contexts.

scholarly journals The effect of improved housing on indoor mosquito density and exposure to malaria in the rural community of Minkoameyos, Centre Region of Cameroon.

2020 ◽  
Author(s):  
Rachel Laure Nguela ◽  
Jude D. Bigoga ◽  
Tedjou N. Armel ◽  
Tallah Tayie Ngobiyo Esther ◽  
Line Leukou Dongmo ◽  
...  
Keyword(s):  
Malaria Transmission ◽  
Rural Community ◽  
Statistical Significance ◽  
Malaria Prevalence ◽  
Reduction Factor ◽  
Mosquito Density ◽  
Chi Square ◽  
Factors Affecting ◽  
Chi Square Test ◽  
House Design

Abstract Background This study evaluated the effectiveness of improved housing on indoor residual mosquito density and exposure to malaria-carrying anophelines in Minkoameyos, a rural community in southern forested Cameroon. Methods Following the identification of housing factors affecting malaria prevalence in 2013, 218 houses were improved by screening the doors and windows, installing plywood ceilings on open eaves and closing holes on walls and doors. Monthly entomological surveys were conducted in a sample of 21 improved and 21 non-improved houses from November 2014 to October 2015. Mosquitoes sampled from night collections on human volunteers were identified morphologically and their parity status determined. Mosquito infectivity was verified through Plasmodium falciparum CSP ELISA and the average entomological inoculation rates determined. A Reduction Factor (RF), defined as the ratio of the values for mosquitoes collected outdoor to those collected indoor was calculated in improved houses (RFI) and non-improved houses (RFN). An Intervention Effect (IE=RFI/RFN) measured the true effect of the intervention. Chi-square test was used to determine variable significance. The threshold for statistical significance was set at P < 0.05. Results A total of 1113 mosquitoes were collected comprising Anopheles sp (58.6%), Culex sp (36.4%), Aedes sp (2.5%), Mansonia sp (2.4%) and Coquillettidia sp (0.2%). Amongst the anophelines were An. gambiae s.l. (95.2%), An. funestus (2.9%), An. ziemanni (0.2%), An. brohieri (1.2%) and An. paludis (0.5%). An. gambiae s.s. was the only Anopheles gambiae siblings found. The intervention reduced the indoor Anopheles density by 1.8 folds (RFI=3.99; RFN=2.21; P=0.001 ). The indoor density of parous Anopheles reduced by 1.7 folds (RFI=3.99; RFN=2.21; P=0.04 ) and that of infected Anopheles by 1.8 folds (RFI=3.26; RFN=1.78; P=0.04 ). Indoor peak biting rates were observed between 02am to 04am in non-improved houses and from 02am to 06am in improved houses. Conclusion Housing improvement contributed to reducing indoor residual anopheline density and malaria transmission. This highlights the need for policy specialists to further evaluate and promote aspects of house design as a complementary control tool that could reduce indoor human–vector contact and malaria transmission in similar epidemiological settings.

Change in perception of sclerotherapy results after exposure to pre–post intervention photographs

2017 ◽  
Vol 33 (4) ◽  
pp. 282-287 ◽  
Author(s):  
Fabricio R Santiago ◽  
Mario Piscoya ◽  
Yung-Wei Chi
Keyword(s):  
Varicose Veins ◽  
Statistical Significance ◽  
Wilcoxon Test ◽  
Clinical Severity ◽  
Post Intervention ◽  
Chi Square ◽  
Severity Scores ◽  
Venous Clinical Severity Score ◽  
Before And After ◽  
Chi Square Test

Objective To evaluate patients’ self-perception of cosmetic improvement before and after they were presented with pre- and postprocedure photographs after sclerotherapy with 75% dextrose. Methods Treatments included sclerotherapy of reticular and varicose veins using 75% dextrose. All treated limbs were photographed and classified according to Clinical, Etiology, Anatomy, and Pathology classification and Venous Clinical Severity Score pre- and posttreatment. The patients were queried before and after viewing the photos during these visits and indicated if they were very unsatisfied, dissatisfied, satisfied, or very satisfied. Nonparametric kappa correlation coefficient and a Chi square test were used to measure associations among agreement (p < 0.05 indicated statistical significance). The paired Wilcoxon test was used to compare statistical differences in mean Venous Clinical Severity Scores measured at different times (p < 0.05 indicated statistical significance). Data were analyzed using STATA software (version 12). Results Individuals were more satisfied with the results of sclerotherapy after exposure to images portraying their limbs two months after the procedure (p = 0.0028). This effect was maintained six months after sclerotherapy (p = 0.0027). Conclusion Patient exposure to pre- and postsurgical photographs is a simple intervention with the potential of improving patient satisfaction up to six months after treatment with sclerotherapy.

scholarly journals Gloves Perforations in Minor Oral Surgical Procedures: A Comparison of Latex and Nitrile Gloves

2021 ◽  
Vol 30 (02) ◽  
pp. 103-106
Author(s):  
Ajeet Kumar ◽  
◽  
Naveed Iqbal ◽  
Javaria Farooq ◽  
Saad Uddin Siddiqui
Keyword(s):  
Local Anesthesia ◽  
Surgical Procedures ◽  
Statistical Significance ◽  
Descriptive Analysis ◽  
P Value ◽  
Dominant Hand ◽  
Chi Square ◽  
Oral Surgical Procedures ◽  
Latex Gloves ◽  
Chi Square Test

OBJECTIVE: This study was performed to compare incidence of perforations in Latex and Nitrile examination gloves during Minor Oral surgical procedures performed under local anesthesia. METHODOLOGY: 100 pairs of latex and 100 pairs of Nitrile examination gloves where used to perform 200 minor oral surgical procedures under local anesthesia. After completion of every minor oral surgical procedure each gloves was examined by Water Inflation method to observe presence or absence of Perforations. A data sheet was used to collect data including type of Gloves used (Latex or Nitrile) presence of perforations, sites of perforations and nature of minor oral surgical procedures. Data was entered and analyzed using SPSS version 20. Descriptive analysis was conducted to calculate frequency and percentages of Number and sites of perforations for both Nitrile and latex examination gloves. Chi Square test was used to find out statistical significance of difference of perforations rate between Nitrile and Latex gloves. P value of < 0.05 was considered significant. RESULTS: Out of 200 latex gloves 23 (11.5) had 29 perforations whereas out of total 200 Nitrile gloves 28 (14%) had 22 perforations. Nitrile gloves had a statistically significant higher rate of perforations as compared to Latex gloves. (P value 0.043). For both Nitrile and Latex gloves left non dominant hand had highest frequency of perforations Latex 18 (81.81%) perforations and Nitrile 18(62.06%). Index finger and thumb were most frequent sites of perforations in both Latex and Nitrile gloves. CONCLUSION: Gloves perforations were more common in Nitrile examination gloves however total number of perforations was more in Latex examination gloves.

scholarly journals Relationship of the Self-perception of Lifestyle with Level of Physical Activity in People with and without Type 2 Diabetes

2019 ◽  
pp. 1-7
Author(s):  
Briseida Mayel Perez-Avelino ◽  
Nicolás Padilla-Raygoza ◽  
Verónica Benitez-Guerrero ◽  
María Luisa Sánchez Padilla ◽  
Vicente Beltrán-Campos ◽  
...  
Keyword(s):  
Physical Activity ◽  
Type 2 Diabetes ◽  
Statistical Significance ◽  
Self Perception ◽  
Chi Square ◽  
Cross Sectional ◽  
Lifestyle Questionnaire ◽  
Chi Square Test ◽  
Relationship Of

Objective: To determine the relationship of the perception of lifestyle with the level of physical activity in people with type 2 diabetes and without type 2 diabetes. Study Design: Analytical cross-sectional observational study in Celaya, Guanajuato, Mexico. Methodology: Sample composed of 100 people with type 2 diabetes and 100 people without type 2 diabetes, the lifestyle questionnaire and IPAQ questionnaire were used. Descriptive statistics were calculated for sociodemographic variables; it was calculated Chi-square test and Odds Ratio.  To demonstrate the statistical significance of results, the value of P was set at .05. Statistical analysis was performed in STATA 13.0 ®. Results: In patients with Type 2 Diabetes predominated females, married, who never went school and elementary and BMI ≥ 25 kg/m2; among patients without Type 2 Diabetes, predominant males, singles, went school or university, BMI ≥25 kg/m2; no relationship was found between lifestyle perception and level of physical activity in adults with type 2 diabetes (X² = 0.0022 gl 1 P = .96) neither it was found a significant relationship between lifestyle perception and level of physical activity in adults without type 2 diabetes (X² = 5.23 gl 1 P = .02 RM = 2.85 95% CI = 0.80 to 10.4). Conclusion: The results show that self-perception of lifestyle and physical activity is different in people with less age, more schooling, males.

scholarly journals ULTRASOUND PREDICTABILITY OF LOWER UTERINE SEGMENT CESAREAN SECTION SCAR THICKNESS

2020 ◽  
pp. 9-11
Author(s):  
Madhu Kumari ◽  
Kumari Bibha ◽  
Abha Sinha ◽  
Debarshi Jana
Keyword(s):  
Cesarean Section ◽  
Gestational Age ◽  
Statistical Significance ◽  
P Value ◽  
Chi Square ◽  
Medical College ◽  
Chi Square Test ◽  
Uterine Scar ◽  
Age Range ◽  
The Given

Objective: The objective of this study is to find out association between scar thickness, assessed sonographically, and intraoperative findings (IOF). Study Design: Descriptive study. Place and Duration of Study: Department of Obstetrics and Gynecology, Sri Krishna Medical College and Hospital, Muzaffarpur, Bihar from June 2019 to May 2020. Methodology: A total of 70 pregnant patients were included in this study. Transabdominal ultrasound was done for scarred uteri. Sonographic findings were co-related with introperative findings. All the given data were entered on SPSS version 23. Age was expressed as mean ± SD. Parity, gestational age, and interval between cesarean sections were expressed as frequencies with percentages. Statistical analysis was done by using Chi-square test for categorical data for association between sonographic scar thickness and intraoperative findings. The statistical significance was set at p-value <0.05. Results: The age range of the patients was 20- 36 years with a mean of 27.91 ±3.690 years. Gestational age at the time of cesarean section was between 27-40 weeks of gestation with a mean of 37 ±2.126 weeks. The interval from previous cesarean was 10 months at the minimum, and 6 years at the maximum with a mean of 2.29 ±1.0 months. Mean scar thickness was 2.5 mm. Association between scar thickness (<1-3 mm) and intaoperative findings of dehiscence and rupture showed a p-value of <0.001. Conclusion: Sonographic assessment of a uterine scar has a practical application to determine the thickness of previous scar, and assess its integrity.

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