scholarly journals The Association of Thyroid Nodules with Metabolic Status: A Cross-Sectional SPECT-China Study

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Yi Chen ◽  
Chunfang Zhu ◽  
Yingchao Chen ◽  
Ningjian Wang ◽  
Qin Li ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Central Obesity ◽  
Thyroid Nodules ◽  
Cross Sectional Study ◽  
Metabolic Status ◽  
Anthropometric Parameters ◽  
Cross Sectional ◽  
Nonalcoholic Fatty Liver ◽  
Imaging Characteristics ◽  
The Status

Purpose. The aim of this study was to investigate the association of thyroid nodules (TNs) and their ultrasound (US) characteristics related to malignancy with metabolic status. Methods. The data were obtained from a cross-sectional study (SPECT-China, 2014-2015). The study included 9898 participants older than 18 years. Participants underwent several checkups, which included the measurement of anthropometric parameters, blood pressure, TSH levels, glucose, and lipid profiles. TN and nonalcoholic fatty liver disease (NAFLD) were diagnosed by US. TN US characteristics, including microcalcification and a taller-than-wide shape, were recorded. Results. Participants with TN [TN(+)] had a higher prevalence of metabolic syndrome (Met-S), obesity, central obesity, hyperlipidaemia, diabetes, hypertension, and NAFLD, especially women (all P≤0.001). After full adjustment, logistic regression analysis indicated that metabolic syndrome, obesity, central obesity, and hyperlipidaemia were all independent risk factors for the increased prevalence of TN in both genders (P<0.05). In terms of TN US imaging characteristics associated with malignancy, being female with obesity, central obesity, and NAFLD had 1.91-fold, 2.09-fold, and 1.75-fold increased risks of developing a taller-than-wide nodule (P=0.014, 0.004, and 0.027, resp.). Conclusions. The status of metabolic disorders might be associated with higher risks of TN in both genders. In women, obesity, central obesity, and NAFLD might contribute to the development of a taller-than-wide nodule. The potential role of metabolic status in the pathogenesis of the thyroid nodule and thyroid cancer remains to be elucidated.

scholarly journals The Relationship and Gender Disparity Between Thyroid Nodules and Metabolic Syndrome Components Based on a Recent Nationwide Cross-Sectional Study and Meta-Analysis

2021 ◽  
Vol 12 ◽  
Author(s):  
Fan Zhang ◽  
Yongze Li ◽  
Xiaohui Yu ◽  
Xichang Wang ◽  
Zheyu Lin ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Central Obesity ◽  
Thyroid Nodules ◽  
Meta Analysis ◽  
Cross Sectional Study ◽  
Cochrane Library ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Relationship

BackgroundMetabolic syndrome (MetS) has a potential connection with thyroid disease, but its relationship with thyroid nodules (TNs) is still controversial. This study aims to clarify the relationship between MetS and TNs, and this relationship in the subgroup of gender.MethodsThe recent nationwide cross-sectional study called Thyroid Disorders, Iodine Status, and Diabetes Epidemiological survey provided the newest data on the relationship between MetS and TNs from China and included 56,729 subjects. We also researched related literature in PubMed, EMBASE, Cochrane Library, and MEDLINE until Oct 30, 2020, in order to perform a meta-analysis. The relevant articles were examined, and the eligible studies were included to assess the association between MetS and TNs.ResultsThe meta-analysis included 15 studies (involving 468,845 subjects). Of these, 14 studies were from the databases, and one study was this cross-sectional data. The meta-analysis showed that TNs were associated with a higher prevalence of MetS (OR=1.87, 95% CI: 1.44–2.45) and the components of MetS, including central obesity (OR=1.41, 95% CI: 1.15–1.72), hypertriglyceridemia (OR=1.13, 95% CI: 1.10–1.15), low high-density lipoprotein cholesterolemia (OR=1.11, 95% CI: 1.02–1.20), abnormal blood pressure (OR=1.68, 95% CI: 1.62–1.75), and hyperglycemia (OR=1.59, 95% CI: 1.46–1.74). Central obesity displayed gender differences, being a risk factor in males (OR=1.38, 95% CI: 1.02–1.86) but not in females (OR=1.47, 95% CI: 0.97–2.23).ConclusionTNs were indeed associated with a higher prevalence of MetS. In addition, its component diseases, such as central obesity, hypertriglyceridemia, abnormal blood pressure, and hyperglycemia, were also associated with TNs. Females with MetS or its components had a higher risk of suffering from TNs than males.

scholarly journals Neck Circumference, a Novel Predictor of Overweight/ Obesity in School Children in Pokhara

Med Phoenix ◽  
2020 ◽  
Vol 5 (1) ◽  
pp. 32-39
Author(s):  
Manisha Maskey ◽  
KK Dutta Gupta ◽  
Meraj Ahmed
Keyword(s):  
Waist Circumference ◽  
School Children ◽  
Good Predictor ◽  
Central Obesity ◽  
Characteristic Curve ◽  
Cross Sectional Study ◽  
Neck Circumference ◽  
Anthropometric Parameters ◽  
Cross Sectional ◽  
High Bmi

Background: Calculating BMI in an individual is a standard anthropometric procedure to estimate overweight/obesity. But it has been observed to be a bad predictor of central obesity. On the other hand, waist circumference, in many studies, has been found to be a good predictor of central obesity but not so frequently used because of tendency to vary throughout the day. In the recent years, NC has been found to have a good correlation with both BMI and WC. The aim of this study was to find out whether neck circumference is a good predictor of Overweight/Obesity or not. Methods: This was a cross sectional study carried out among the school children, aged 12 to 15 years, in Pokhara city, Nepal. In total, 408 students, 238 males and 170 females were screened. Anthropometric markers of obesity measured: included body mass index (BMI), waist circumference (WC), and compared with neck circumference (NC) of the same subjects. Pearson’s correlation test was used to see the correlation between NC with BMI and WC, and receiver operating characteristic curve analysis was used to determine the best cut off value of neck circumference in predicting high BMI. Results: Among 408 students, 238 (58.3%) were male and 170 (41.7%) were female. Among them 37 (9.1%) were overweight and 32 (7.8%) were obese. All the anthropometric parameters were significantly higher in cases, except height in male, than in controls. NC was significantly correlated with age, BMI, and waist circumference in both boys and girls. The best cut-off value of neck circumference by ROC to identify boys with a high BMI was 29.5 with sensitivity of (76%), specificity (54%), and for girls was 28.5 with sensitivity of (97%), specificity (48%). Conclusion: Statistically significant positive correlation was found between NC with BMI and WC. The value of NC as a screening tool has been found comparably lower in compare to WC.

scholarly journals Demographic and Biochemical Parameters of Community Survey Participants with Metabolic Syndrome from Terai Region of Nepal

2021 ◽  
Author(s):  
Birendra Kumar Jha ◽  
Mingma Lhamu Sherpa ◽  
Binod Kumar Dahal ◽  
Jitendra Kumar Singh ◽  
Chamma Gupta
Keyword(s):  
Metabolic Syndrome ◽  
Glucose Tolerance ◽  
Biochemical Parameters ◽  
Central Obesity ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
Atherogenic Dyslipidemia ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Mean

Introduction: The Metabolic Syndrome (MS) is a multifactorial disease associated with central obesity, hypertension, atherogenic dyslipidemia and impaired glucose tolerance. Low grade inflammatory and a prothrombotic state are also involved in MS. Aim: To explore the demographic and biochemical parameters of participants with MS in Terai region of Nepal using community based cross-sectional study. Materials and Methods: A cross-sectional study was carried out during September 2019-December 2019 in adult participants with central obesity (n=378) selected from three districts of Terai region of Nepal. International Diabetes Federation (IDF) criteria were used to define MS. The C-reactive protein-ultra sensitive, fibrinogen, and apolipoprotein-B were estimated as inflammatory, prothrombotic, and atherogenic dyslipidemia markers, respectively. Results: The MS was present in 283 participants with central obesity. The mean (±SD) age, height, weight, and BMI of the participants with MS were 46.36±12.52 years, 5.56±0.11 feet, 66.54±13.45 kg and 27.28±4.98 kg/m2, respectively. The mean (±SD) of biochemical factors were significantly different than their respective normal ranges: decreased serum High Density Lipoprotein (HDL) cholesterol in mg/dL (male: 34.50±9.93, p<0.001, female: 36.77±7.28, p<0.001), raised serum triglycerides level- 184.96±85.72 mg/dL (p<0.001), and impaired fasting serum glucose level 108.14±48.27 mg/dL (p=0.002). Significant increase in inflammatory (CRP-US: 1.12±2.17 mg/L, p<0.001), prothrombotic (fibrinogen: 3.42±1.04 gm/L, p<0.001) and atherogenic dyslipidemia marker (Apo-B: 149.35±59.13 mg/dL, p=0.003) from normal values were observed in subjects with MS. Conclusion: Lowered serum HDL cholesterol, increased triglycerides followed with impaired fasting glucose tolerance were observed as the major abnormal biochemical parameters and increased inflammatory and prothrombotic activities were present among participants with MS.

scholarly journals Prevalence of Metabolic Syndrome and Its Components in Adults with Central Obesity at Janakpur Zone, Nepal

2021 ◽  
Vol 18 (4) ◽  
pp. 681-685
Author(s):  
Birendra Kumar Jha ◽  
Mingma Lhamu Sherpa ◽  
Binod Kumar Dahal ◽  
Jitendra Kumar Singh
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Central Obesity ◽  
International Diabetes Federation ◽  
Cross Sectional Study ◽  
High Density Lipoproteins ◽  
Cluster Sampling ◽  
Cross Sectional ◽  
The Metabolic Syndrome

Background: Urbanization, surplus energy uptake, decreased physical activities are general risk factors of metabolic syndrome However, it’s status, and associated components remain unexplored in the Terai region of Nepal. This study evaluated the prevalence of metabolic syndrome and its components among adults with central obesity of Terai region of Nepal using International Diabetes Federation criteria.Methods: Community based cross-sectional study was conducted in three Terai districts of Janakpur Zone, Nepal. A total of 378 adults having central obesity were selected using cluster sampling by camp approach. Interview, physical and clinical examination, measurement of fasting blood sugar, and lipid profile were conducted for all participants. The prevalence of metabolic syndrome and its components with 95% CI were estimated.Results: The metabolic syndrome prevalence was 74.9% (95% CI:70.2-79.2%), with no significant differences between male (77.7%, 95% CI:71.0-83.5%) and female (72.2%, 95% CI: 65.2-78.3%). The most common factors observed were low high density lipoproteins with highly significant differences between male (77.7%, 95% CI:71.0-83.5%)) and female (90.2%, 95% CI: 85.094.0%-; p=0.001) and hypertriglyceridemia with significant differences between male (57.6%, 95% CI: 50.1-64.5%) and female (46.9%, 95% CI: 39.7-54.2%; p=0.037). Conclusions: Higher prevalence of metabolic syndrome and its risk factors in Janakpur of Nepal likely suggest lack of awareness and health promotion activities for metabolic syndrome and indicate an urgency for a public health program to maintain quality of life. Keywords: Metabolic syndrome; Nepal; prevalence; risk factors; terai

scholarly journals Anthropometric parameters’ cut-off points and predictive value for metabolic syndrome in women from Cartagena, Colombia

2014 ◽  
Vol 56 (2) ◽  
pp. 146 ◽  
Author(s):  
Gustavo José Mora-García ◽  
Doris Gómez-Camargo ◽  
Enrique Mazenett ◽  
Ángelo Alario ◽  
Álvaro Fortich ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Latin American ◽  
Predictive Value ◽  
Characteristic Curve ◽  
Cross Sectional Study ◽  
Adult Women ◽  
Anthropometric Parameters ◽  
Cross Sectional ◽  
Body Adiposity ◽  
Cartagena De Indias

Objective. To estimate anthropometric parameters’ (APs) cut-off points and association for metabolic syndrome (MetS). Materials and methods. A cross-sectional study was car­ried out with a total of 434 adult women from Cartagena de Indias, Colombia, in 2012. APs measured were waist circumference (WC), body mass index (BMI), body adiposity index (BAI), waist-hip ratio (WHR) and waist-height ratio (WHtR). Cut-off points were estimated by a receiver op­erating characteristic curve (ROC). Logistic regression was applied to estimate possible associations. Results. Cut-off points for WC, BMI, BAI, WHR and WHtR were 85 cm, 28 kg/m2, 39%, 0.80 and 56, respectively. Only WHtR was associated to MetS (OR=1.11, CI95% [1.07-1.15]). Conclu­sion. WC cut-off point was higher than those proposed for Latin-American women by the Joint Interim Statement (JIS). WHtR had a low predictive value for MetS.

scholarly journals Prevalence and correlates of metabolic syndrome and its components in nearly 10 million participants of northwestern China: a cross-sectional study

2020 ◽  
Author(s):  
yinxia su ◽  
Wenli Li ◽  
Yaoqin Lu ◽  
Mingyue Xue ◽  
Muyaseer Haireti ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Metabolic Syndrome ◽  
Ethnic Groups ◽  
Central Obesity ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Chinese Adults ◽  
Cross Sectional ◽  
Low Hdl

Abstract Background The prevalence of metabolic syndrome (MetS) of comprehensive population are always lower than mono- population. However, studies on MetS and its components of it and its subgroups (different ages, genders, races, regions) based on big data and using a same diagnosis criterion are rare. Method: A total of 9,745,640 Chinese adults aged ≥ 18 years in Xinjiang,the largest autonomous region of Multi-ethnic, were enrolled in the study. MetS was defined by modified Adults Treatment Panel (ATP III) criteria.Prevalence of metabolic syndrome and its components were calculated. To further explore the correlates of MetS and its components logistic regression were used. Results The overall prevalence of MetS was 20.85% [Sex: 20.06% in female, 21.56% in man; Age: 39.22% in 60 year older followed by 40–59 year 26.32% and 18–39 years 9.56%; Ethnicity: 28.19% in Hui followed by Han (26.39%), Uyghur(18.56%), Other(18.61%), Kazak(17.98%), Mongolian (17.87%), Kyrgyz(14.44%)], living in city and town (23.03%) or north(24.78%) had higher prevalence of MetS than living in rural (19.94%) and South (17.66%). Although the prevalence of hypertension, smoking, drinking and lack of physical activity in Kyrgyz, Mongolian and Kazakh were higher than those of other ethnic groups, the risk of MetS was lower than that of other. The results also showed that although their risk of central obesity and hypertension was higher than that of Han, Hui, Uygur and other, the risk of high-TG, low HDL-C and Elevated-FPG was significantly lower than that of other ethnic groups. Among them, the Mongolian had the lowest risk of high-TG and low-HDL-C, while the Kazakh had the lowest risk of elevated-FPG. In addition, except that the risk of central obesity in males was lower than that in females, the other components of males were higher than those in females, but the risk of MetS was lower than that in females. The risk of MetS and its components in the elderly was significantly higher than that in the young, and physical activity did not show reduce the risk of MetS in the general population. Conclusion The reason why the prevalence of MetS in the comprehensive population is lower than that in most mono-population may be that some subgroups of the population have the ability to resist risk factors in terms of genetic structure such as Kyrgyz, Mongolian, Kazak, and the influence in this aspect may exceed that of lifestyle. Within each subgroup, the prevalence of MetS is still increasing. Central obesity is an important risk factor for women with MetS. Elevated-FPG and high-TG are the most important risk factors of MetS in Han, Hui. Climate and lifestyle are the main causes of MetS in northern Xinjiang and city and town residents.

scholarly journals Association of Metabolic Syndrome Parameters with Kidney Stones in Indonesia

2019 ◽  
Vol 8 (2) ◽  
pp. 88-98
Author(s):  
La’elatul Fazriyah ◽  
Mahalul Azam ◽  
Indah Septiani ◽  
Yuni Wijayanti
Keyword(s):  
Metabolic Syndrome ◽  
Kidney Stones ◽  
Kidney Stone ◽  
Central Obesity ◽  
Secondary Data ◽  
Cross Sectional Study ◽  
Stone Disease ◽  
Dominant Factor ◽  
Chi Square ◽  
Cross Sectional

Kidney stone disease is common throughout the world. Elevated prevalence of kidney stones is often associated with metabolic syndrome itself. This study aimed to assess the association between kidney stones and metabolic syndrome parameters in differences gender. This was a cross-sectional study with Chi-square and multivariate logistic regression for data analysis from the secondary data Riskesdas 2013 with 26,063 respondents. Diagnosis of kidney stone based on Riskesdas 2013 interview, metabolic syndrome based on NCEP ATP-III and PERKENI. Result showed that there were 226 (0.9%) diagnosed kidney stones cases by doctors. After adjustment age, central obesity was dominant factor which associated with the risk of kidney stones in male (OR 1.9; 95% CI 1.3-2.9; p=0.003) and metabolic syndrome was dominant factor which associated with the risk of kidney stones in female (OR 6.1; 95% CI 3.4-11.3; p<0.001). The conclusion was that metabolic syndrome and central obesity were associated with risk of kidney stones.

scholarly journals Correlation of Uric Acid Levels and Parameters of Metabolic Syndrome

2017 ◽  
pp. 481-487 ◽  
Author(s):  
L. CIBIČKOVÁ ◽  
K. LANGOVÁ ◽  
H. VAVERKOVÁ ◽  
V. KUBÍČKOVÁ ◽  
D. KARÁSEK
Keyword(s):  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Uric Acid ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
Anthropometric Parameters ◽  
Cross Sectional ◽  
Hypertriglyceridemic Waist ◽  
Low Hdl ◽  
Hypertriglyceridemic Waist Phenotype

Hyperuricemia has been described as associated with the risk of development metabolic syndrome; however the relationship between the uric acid level and particular parameters of metabolic syndrome remained unclear. We performed a cross-sectional study on a cohort of 833 dyslipidemic patients and correlated their levels of uric acid with parameters of insulin resistance, lipid metabolism, C-reactive protein, anthropometric parameters. We also defined patients with hypertriglyceridemic waist phenotype and compered their uric acid levels with those without this phenotype. We found that levels of uric acid are associated with parameters of metabolic syndrome. Specifically, dyslipidemia characteristic for metabolic syndrome (low HDL cholesterol and high triglycerides) correlates better with uric acid levels than parameters of insulin resistance. Also waist circumference correlates better with uric acid levels than body mass index. Patients with hypertriglyceridemic waist phenotype had higher levels of uric acid when compared with patients without this phenotype. Serum uric acid levels are even in low levels linearly correlated with parameters of metabolic syndrome (better with typical lipid characteristics than with parameters of insulin resistance) and could be associated with higher cardiovascular risk.

scholarly journals Hyperhomocysteinemia Concurrent with Metabolic Syndrome Is Independently Associated with Chronic Kidney Disease among Community-Dwelling Adults in an Urban Korean Population

2020 ◽  
Vol 17 (18) ◽  
pp. 6810
Author(s):  
Hana Moon ◽  
Hae-Jin Ko ◽  
A-Sol Kim
Keyword(s):  
Metabolic Syndrome ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Odds Ratio ◽  
Central Obesity ◽  
Cross Sectional Study ◽  
Community Dwelling ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Difference

Elevated homocysteine (Hcy) levels and metabolic syndrome (MetS) are associated with chronic kidney disease (CKD). We investigated the combined effects of hyperhomocysteinemia (HHcy) and MetS on CKD among community-dwelling adults in an urban area of South Korea. We also identified the combination of HHcy and individual MetS components associated with the maximal risk of CKD. A retrospective cross-sectional study involving 19,311 health examinees between 2 January 2011 and 31 December 2015 was conducted. The participants were divided into four groups—namely, the HHcy−/MetS−, HHcy−/MetS+, HHcy+/MetS−, and HHcy+/MetS+ groups. CKD was defined as a low eGFR <60 mL/min/1.73 m2 or albuminuria. The HHcy+/MetS+ group had a higher risk of CKD than the HHcy−/MetS+ group (odds ratio (OR): 1.750, p = 0.002 for males; OR: 3.224, p < 0.001 for females). The HHcy+/MetS+ group had a higher CKD risk than the HHcy+/MetS− group; however, the difference was not statistically significant (OR: 1.070, p = 0.712 for males; OR: 1.847, and p < 0.074 for females). HHcy concurrent with MetS increased the CKD risk. Among the combinations of HHcy and MetS components, the coexistence of HHcy and central obesity had the greatest effect on CKD. Therefore, the timely detection and treatment of HHcy and MetS are important for preventing CKD.

PREVALENCE OF METABOLIC SYNDROME IN COPD CASES IN CENTRAL INDIA AND ITS CORRELATION WITH BMI

2021 ◽  
pp. 73-75
Author(s):  
Aditya Tejwani ◽  
Lokendra Dave ◽  
Anubhav Agrawal ◽  
Simmi Dube
Keyword(s):  
Metabolic Syndrome ◽  
Adult Population ◽  
Central India ◽  
Cross Sectional Study ◽  
Anthropometric Parameters ◽  
Cross Sectional ◽  
Middle Income ◽  
Institutional Ethics ◽  
Copd Patients ◽  
Gandhi Medical College

BACKGROUND: COPD is the third leading cause of death worldwide with more than 90% of COPD deaths occuring in low and middle income countries. While metabolic syndrome is a cluster of the most dangerous cardiovascular risk factors , dened to be associated with prothrombotic and proinammatory states. About 20%- 25% adult population of the world have Metabolic syndrome and are three times more likely to have coronary artery disease or stroke . Increasing evidence shows association between Metabolic Syndrome in COPD. However, the frequency of Metabolic Syndrome and its individual components are not still been clearly shown especially in Indian population in central India . METHODS: This was a cross sectional study conducted at Department of Respiratory Medicine, Gandhi Medical College & Hamidia hospital, Bhopal. 100 spirometrically conrmed COPD cases were enrolled after permission from institutional ethics committee . Detailed history , clinical examination , laboratory parameters and anthropometric parameters were taken. RESULTS: Mean age of patients with COPD was 60.34±10.39 years .Mean weight, height and BMI of patients was 55.86±9.43 2. 2 kg, 160.47±7.58 m and 21.65±3.01kg/m .Majority - 57% patients had normal BMI (18.5 to 22.9 kg/m ). About 25% and 11% patients were overweight and underweight respectively. Metabolic syndrome was found to be present in 32% of the patients with COPD. BMI of patients with metabolic syndrome was signicantly higher as compared to COPD patients without metabolic syndrome (p<0.01). CONCLUSION: The prevalence of metabolic syndrome in COPD was 32% and BMI in COPD patients with metabolic syndrome was signicantly higher than those without metabolic syndrome .

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