scholarly journals Intermittent Hypoxic Training at Lactate Threshold Intensity Improves Aiming Performance in Well-Trained Biathletes with Little Change of Cardiovascular Variables

2019 ◽  
Vol 2019 ◽  
pp. 1-17 ◽  
Author(s):  
Miłosz Czuba ◽  
Grzegorz Bril ◽  
Kamila Płoszczyca ◽  
Zofia Piotrowicz ◽  
Małgorzata Chalimoniuk ◽  
...  
Keyword(s):  
Aerobic Capacity ◽  
Lactate Threshold ◽  
Standing Position ◽  
Control Group ◽  
Threshold Intensity ◽  
Active Recovery ◽  
Intermittent Hypoxic Training ◽  
Beneficial Effects ◽  
Hypoxic Training ◽  
Aiming Performance

The main objective of this research was to evaluate the efficacy of intermittent hypoxic training (IHT) on aiming performance and aerobic capacity in biathletes. Fourteen male biathletes were randomly divided into a hypoxia group (H) (n = 7), which trained three times per week in a normobaric hypoxic environment (FiO2 = 16.5%, 2000 m a.s.l.) with lactate threshold intensity (LT) determined in hypoxia, and a control group (C) (n = 7), which exercised under normoxic conditions with LT intensity determined in normoxia. The training program included three weekly microcycles, followed by three days of recovery. The main part of the interval workout consisted of four 7 min (1st week), 8 min (2nd week), or 9 min (3rd week) running bouts at treadmill separated by 2 minutes of active recovery. After the warm-up and during the rest between the bouts, the athletes performed aiming to the target in the standing position with a sporting rifle (20 s). The results showed that the IHT caused a significant (p<0.05) increase in retention time in the target at rest (RT9rest) by 14.4% in hypoxia, whereas RT postincremental test (RT9post) increased by 27.4% in normoxia and 26.7% in hypoxia. No significant changes in this variable were found in group C. Additionally, the capillary oxygen saturation at the end of the maximal effort (SO2capillary max) in hypoxia increased significantly (p<0.001) by ∼4% after IHT. The maximal workload during the incremental test (WRmax) in normoxia also increased significantly (p<0.001) by 6.3% after IHT. Furthermore, in absolute and relative values of VO2max in normoxia, there was a propensity (p<0.07) for increasing this value by 5% in group H. In conclusion, the main findings of this study showed a significant improvement in resting and postexercise aiming performance in normoxia and hypoxia. Furthermore, the results demonstrated beneficial effects of the IHT protocol on aerobic capacity of biathletes.

scholarly journals Exposure to Normobaric Hypoxia Combined with a Mixed Diet Contributes to Improvement in Lipid Profile in Trained Cyclists

Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3481
Author(s):  
Kamila Płoszczyca ◽  
Miłosz Czuba ◽  
Józef Langfort ◽  
Marcin Baranowski
Keyword(s):  
Lipid Profile ◽  
Lactate Threshold ◽  
National Level ◽  
Control Group ◽  
Mixed Diet ◽  
Training Method ◽  
Training Experience ◽  
Intermittent Hypoxic Training ◽  
Hypoxic Conditions ◽  
Hypoxic Training

This study aimed to analyze the effects of live high-train low method (LH-TL) and intermittent hypoxic training (IHT) with a controlled mixed diet on lipid profile in cyclists. Thirty trained male cyclists at a national level with at least six years of training experience participated in the study. The LH-TL group was exposed to hypoxia (FiO2 = 16.5%) for 11–12 h a day and trained under normoxia for 3 weeks. In the IHT group, participants followed the IHT routine three times a week under hypoxia (FiO2 = 16.5%) at lactate threshold intensity. The control group (N) lived and trained under normoxia. The results showed that the 3-week LH-TL method significantly improved all lipid profile variables. The LH-TL group showed a significant increase in HDL-C by 9.0% and a decrease in total cholesterol (TC) by 9.2%, LDL-C by 18.2%, and triglycerides (TG) by 27.6%. There were no significant changes in lipid profiles in the IHT and N groups. ∆TG and ∆TC were significantly higher in the LH-TL group compared to the N group. In conclusion, hypoxic conditions combined with a mixed diet can induce beneficial changes in lipid profile even in highly trained athletes. The effectiveness of the hypoxic stimulus is closely related to the hypoxic training method.

scholarly journals Effect of intermittent hypoxic training on orthostatic tolerance in humans before and after simulated microgravity

2020 ◽  
Author(s):  
VP Katuntsev ◽  
TV Sukhostavtseva ◽  
AN Kotov ◽  
MV Baranov
Keyword(s):  
Orthostatic Intolerance ◽  
Bed Rest ◽  
Daily Basis ◽  
Tilt Test ◽  
Control Group ◽  
Orthostatic Tolerance ◽  
Pronounced Increase ◽  
Intermittent Hypoxic Training ◽  
Hypoxic Training ◽  
Before And After

Reduced orthostatic tolerance (OT) is a serious concern facing space medicine. This work sought to evaluate the effects of intermittent hypoxic training (IHT) on OT in humans before and after 3 days of head-down bed rest (HDBR) used to model microgravity. The study was carried out in 16 male volunteers aged 18 to 40 years and included 2 series of experiments with 11-day and 21-day IHT administered on a daily basis. During the first IHT session, the concentration of oxygen in the inspired gas mixture was 10%; for other sessions it was adjusted to 9%. OT was assessed by a 20-minute-long orthostatic tilt test (OTT) conducted before and after HDBR. Before HDBR, orthostatic intolerance was observed in 3 participants, while after HDBR, it was observed in 9 of 16 volunteers (p < 0.05). During OTT conducted after HDBR, the heart rate (HR) exceeded control values by 26.8% (p < 0.01). Preexposure to any of the applied IHT regimens led to a reduction in the number of volunteers with orthostatic intolerance. After the 11-day IHT program, there was a less pronounced increase in HR during OTT before HDBR; with the extended IHT regimen, less pronounced changes were observed for HR, systolic, diastolic and mean blood pressure (BP). The increase in HR during OTT after HDBR was significantly lower in the group that had completed the 11-day IHT program, while BP remained stable. The changes in HR and systolic BP were less pronounced in the group that had completed the 21-day IHT program than in the control group (p < 0.05). Thus, IHT reduced the risk of orthostatic disorders and mitigated changes in cardiovascular parameters during the orthostatic test.

scholarly journals Effects of moderate-intensity intermittent hypoxic training on health outcomes of patients recovered from covid-19: the AEROBICOVID study protocol for a randomised controlled trial

2021 ◽  
Author(s):  
Atila Alexandre Trapé ◽  
Marta Camacho-Cardenosa ◽  
Alba Camacho-Cardenosa ◽  
Eugenio Merellano-Navarro ◽  
Jhennyfer Aline Lima Rodrigues ◽  
...  
Keyword(s):  
Health Outcomes ◽  
Physical Training ◽  
Controlled Trial ◽  
Training Session ◽  
Moderate Intensity ◽  
Control Group ◽  
Composition Analysis ◽  
Double Blind Study ◽  
Intermittent Hypoxic Training ◽  
Hypoxic Training

Abstract Background: Recent studies point to a lower number and a reduction in the severity of cases in higher altitude cities, with decreased oxygen concentration. Specific literature has shown several benefits of physical training, so, in this sense, physical training with hypoxic stimulus appears as an alternative that supports the conventional treatments of the COVID-19 patient's recovery. Thus, this study's primary aim is to analyse the effects of moderate-intensity intermittent hypoxic training on health outcomes in COVID-19 recovered patients. Methods: A clinical trial controlled double-blind study was designed. Participants (30-69 years old) will be recruited among those with moderate to severe COVID-19 symptoms, approximately 30 days after recovery. They will be included in groups according to the training (T) and recovery (R) association with hypoxia (H) or normoxia (N): a) TH:RH, b) TN:RH, c) TN:RN, and, last, d) the control group. The 8-week exercise bike intervention will be carried out with a gradual load increase according to the established periods, three times a week in sets of 5 minutes, 90 to 100% of the anaerobic threshold (AT), and a 2,5-minute break. Blood will be collected for genotyping. First, after four weeks (partial), after eight weeks, and later, four weeks after the end of the physical training intervention, participants will perform assessments. The primary outcome is the maximum oxygen consumption (VO2max). The secondary outcomes include lung function, inflammatory mediators, haematological, autonomic parameters, AT, body composition analysis, quality of life, mental health, anthropometric measurements, and physical fitness. The statistical analysis will be executed using the linear regression model with mixed effects at a 5% significance level. Discussion: This study is designed to provide evidence to support the clinical benefits of moderate-intensity intermittent hypoxic training as a part of the treatment of patients recovered from COVID-19. It may also provide evidence on the efficacy and safety of intermittent hypoxic training in different health conditions. Lastly, this study presents an innovative strategy enabling up to 16 participants in the same training session.Trial registration: Brazilian Clinical Trials Registry, RBR-5d7hkv. Registered after the start of inclusion; 3 November 2020; https://ensaiosclinicos.gov.br/rg/RBR-5d7hkv

scholarly journals Effects of moderate-intensity intermittent hypoxic training on health outcomes of patients recovered from COVID-19: the AEROBICOVID study protocol for a randomized controlled trial

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Átila Alexandre Trapé ◽  
Marta Camacho-Cardenosa ◽  
Alba Camacho-Cardenosa ◽  
Eugenio Merellano-Navarro ◽  
Jhennyfer Aline Lima Rodrigues ◽  
...  
Keyword(s):  
Health Outcomes ◽  
Physical Training ◽  
Controlled Trial ◽  
Training Session ◽  
Moderate Intensity ◽  
Control Group ◽  
Composition Analysis ◽  
Double Blind Study ◽  
Intermittent Hypoxic Training ◽  
Hypoxic Training

Abstract Background Recent studies point to a lower number and reduced severity of cases in higher altitude cities with decreased oxygen concentration. Specific literature has shown several benefits of physical training, so, in this sense, physical training with hypoxic stimulus appears as an alternative that supports the conventional treatments of the COVID-19 patient’s recovery. Thus, this study’s primary aim is to analyze the effects of moderate-intensity intermittent hypoxic training on health outcomes in COVID-19 recovered patients. Methods A clinical trial controlled double-blind study was designed. Participants (30–69 years old) will be recruited among those with moderate to severe COVID-19 symptoms, approximately 30 days after recovery. They will be included in groups according to the training (T) and recovery (R) association with hypoxia (H) or normoxia (N): (a) TH:RH, (b) TN:RH, (c) TN:RN, and last (d) the control group. The 8-week exercise bike intervention will be carried out with a gradual load increase according to the established periods, three times a week in sets of 5 min, 90 to 100% of the anaerobic threshold (AT), and a 2.5-min break. Blood will be collected for genotyping. First, after 4 weeks (partial), after 8 weeks, and later, 4 weeks after the end of the physical training intervention, participants will perform assessments. The primary outcome is the maximum oxygen consumption (VO2peak). The secondary outcomes include lung function, inflammatory mediators, hematological, autonomic parameters, AT, body composition analysis, quality of life, mental health, anthropometric measurements, and physical fitness. The statistical analysis will be executed using the linear regression model with mixed effects at a 5% significance level. Discussion This study is designed to provide evidence to support the clinical benefits of moderate-intensity intermittent hypoxic training as a part of the treatment of patients recovered from COVID-19. It may also provide evidence on the efficacy and safety of intermittent hypoxic training in different health conditions. Lastly, this study presents an innovative strategy enabling up to 16 participants in the same training session. Trial registration ClinicalTrials.gov RBR-5d7hkv. Registered after the start of inclusion on 3 November 2020 with the Brazilian Clinical Trials Registry

7-day Simulated Intermittent Hypoxic Training Improves Maximal Aerobic Capacity In 400m Or 800m Runners

2015 ◽  
Vol 47 ◽  
pp. 829
Author(s):  
Marie Oriishi ◽  
Masahiro Hagiwara ◽  
Kazunori Asaba ◽  
Takashi Kawahara ◽  
Yasuhiro Suzuki
Keyword(s):  
Aerobic Capacity ◽  
Maximal Aerobic Capacity ◽  
Intermittent Hypoxic Training ◽  
Hypoxic Training

Effect of Intermittent Hypoxic Training Followed by Intermittent Hypoxic Exposure on Aerobic Capacity of Long Distance Runners

2016 ◽  
Vol 30 (6) ◽  
pp. 1708-1720 ◽  
Author(s):  
Fernanda P. Nakamoto ◽  
Rafael K. Ivamoto ◽  
Marilia dos S. Andrade ◽  
Claudio A.B. de Lira ◽  
Bruno M. Silva ◽  
...  
Keyword(s):  
Aerobic Capacity ◽  
Hypoxic Exposure ◽  
Distance Runners ◽  
Long Distance ◽  
Intermittent Hypoxic Training ◽  
Hypoxic Training

scholarly journals The Effects of Intermittent Hypoxic Training on Anaerobic and Aerobic Power in Boxers

2020 ◽  
Vol 17 (24) ◽  
pp. 9361
Author(s):  
Tadeusz Ambroży ◽  
Marcin Maciejczyk ◽  
Andrzej T. Klimek ◽  
Szczepan Wiecha ◽  
Arkadiusz Stanula ◽  
...  
Keyword(s):  
Peak Power ◽  
Anaerobic Power ◽  
Training Session ◽  
Endurance Performance ◽  
Peak Oxygen Uptake ◽  
Control Group ◽  
Intermittent Hypoxic Training ◽  
Time To Peak ◽  
Hypoxic Training ◽  
Before And After

Background: The aim of the study was to evaluate the effects of intermittent hypoxic training (IHT) on anaerobic and aerobic fitness in elite, national boxers. Methods: The study was conducted over a period of 6 weeks. It comprised 30 national championship boxers, divided into 2 groups: the experimental and control. Both groups performed the same boxing training twice a day (morning and afternoon training). In the afternoon, the experimental group performed training under normobaric conditions in a hypoxic chamber (IHT), while the control group undertook exercise in standard normoxic conditions. In both groups, before and after the 6-week programme, basic anthropometric indices as well as anaerobic (Wingate Test) and aerobic (graded test) fitness were assessed. Results: There was a significant increase in anaerobic peak power (988.2 vs. 1011.8 W), mean anaerobic power (741.1 vs. 764.8 W), total work (22.84 vs. 22.39 kJ), and a decrease in fatigue index (20.33 vs. 18.6 W·s−1) as well as time to peak power (5.01 vs. 4.72 s). Such changes were not observed in the control group. In both groups, no significant changes in endurance performance were noted after the training session – peak oxygen uptake did not significantly vary after IHT. Conclusions: Our results have practical application for coaches, as the IHT seems to be effective in improving anaerobic performance among boxers.

scholarly journals Physical Training of 9- to 10-Year-Old Children With Obesity to Lactate Threshold Intensity

2010 ◽  
Vol 22 (3) ◽  
pp. 477-485 ◽  
Author(s):  
Sijie Tan ◽  
Chunhua Yang ◽  
Jianxiong Wang
Keyword(s):  
Body Composition ◽  
Training Program ◽  
Functional Capacity ◽  
Exercise Intensity ◽  
Physical Training ◽  
Lactate Threshold ◽  
Exercise Program ◽  
Control Group ◽  
Threshold Intensity ◽  
Obese Children

The purpose of this study was to apply the lactate threshold concept to develop a more evidence-informed exercise program for obese children. 60 obese children (26 girls and 34 boys, age: 9–10 years, BMI: 25.4 ± 2.2kg/m2) were recruited and half of them were randomly selected to be trained for eight weeks with a controlled exercise intensity at lactate threshold. The trained children achieved significant improvements on their body composition and functional capacity compared with the control group. The findings suggested that the training program with intensity at lactate threshold is effective and safe for 9–10 year old children with obesity.

Dietary Quercetin Alleviated DSS-induced Colitis in Mice Through Several Possible Pathways by Transcriptome Analysis

2020 ◽  
Vol 21 (15) ◽  
pp. 1666-1673 ◽  
Author(s):  
Yuanyang Dong ◽  
Jiaqi Lei ◽  
Bingkun Zhang
Keyword(s):  
Antioxidant Capacity ◽  
Underlying Mechanism ◽  
Control Group ◽  
Sequencing Analysis ◽  
Colon Tissue ◽  
Beneficial Effects ◽  
Intestinal Integrity ◽  
Inflammatory Bowel ◽  
Vegetables And Fruits ◽  
Key Pathways

Background: The prevalence of inflammatory bowel disease is rapidly increasing around the world. Quercetin is a flavonoid commonly found in vegetables and fruits and has been reported to exert numerous pharmacological activities such as enhancing antioxidant capacity or suppressing inflammation. Objective: We aimed to explore whether quercetin was effective for IBD and the underlying mechanism of quercetin for the ameliorative effects on the DSS-induced colitis in mice. Methods: Thirty-six mice were randomly assigned to three treatments, including the control group (Ctr), DSS-induced colitis group (DSS) and DSS-induced colitis supplemented with 500 ppm quercetin (DQ500). Colitis was induced by DSS intake, and body weight was recorded every day. After six days administration of DSS, intestinal permeability was measured, and the liver was taken for antioxidant enzyme tests. Colonic tissue was taken for the histopathlogical score and RNA-sequencing analysis. Results: In this experiment, dietary quercetin for 500ppm alleviated the DSS-induced colitis, possibly by strengthening intestinal integrity, liver antioxidant capacity. Based on the results of the transcriptome of colon tissue, several key genes were modulated by quercetin. ERK1/2-FKBP pathway and RXR-STAT3 pathway were involved in the development of IBD, furthermore, in the down-regulation of S100a8/9, FBN2 contributed to lowering the risk of colongenesis. Conclusion: We demonstrated that dietary quercetin alleviated the DSS-induced colitis in mice. This is most likely due to its beneficial effects on intestinal integrity and modulation of several key pathways. Based on our research, quercetin was a promising candidate for IBD and its pharmaceutical effects on both IBD and colongenesis need further research.

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