scholarly journals Infantile Iatrogenic Cushing Syndrome due to Topical Steroids

2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Lulwah Alkhuder ◽  
Horia Mawlawi
Keyword(s):  
Pituitary Adenoma ◽  
Young Children ◽  
Cushing Syndrome ◽  
Topical Steroids ◽  
Age Group ◽  
Adrenal Hyperplasia ◽  
Inappropriate Use ◽  
Endogenous Release ◽  
Free Plasma ◽  
Parenteral Preparation

Cushing syndrome is an endocrinological disorder characterized by increased free plasma glucocorticoids level. It is either due to an excessive endogenous release of steroids (e.g., pituitary adenoma or adrenal hyperplasia) or exogenous administration of steroids. In children, iatrogenic Cushing syndrome is the most common form of Cushing syndrome occurring in this age group. The vast majority of cases are due to oral or parenteral preparation of steroids, which are commonly prescribed for pulmonary, hematological, renal, or autoimmune pathologies. Topical preparations can rarely cause Cushing syndrome in young children, and only a few cases were reported in the literature, where the patients were older than 5 months of age. In this report, we present a three-month-old girl who developed iatrogenic Cushing syndrome due to prolonged and inappropriate use of topical clobetasol cream for napkin dermatitis.

scholarly journals Cushing Syndrome due to Inappropriate Corticosteroid Topical Treatment of Undiagnosed Scabies

2018 ◽  
Vol 3 (3) ◽  
pp. 82 ◽  
Author(s):  
Guadalupe Estrada-Chávez ◽  
Roberto Estrada ◽  
Daniel Engelman ◽  
Jesus Molina ◽  
Guadalupe Chávez-López
Keyword(s):  
Risk Factor ◽  
Topical Treatment ◽  
Cushing Syndrome ◽  
Important Risk Factor ◽  
Topical Steroids ◽  
Over The Counter ◽  
Inappropriate Use ◽  
Topical Corticosteroids ◽  
Lack Of Information

The uncontrolled sale of topical corticosteroids has become an important risk factor for the development of iatrogenic Cushing syndrome in children, especially in countries where medications are sold over the counter. This is exacerbated by the lack of information for both the patients and pharmacists. This report documents a series of eight cases of iatrogenic Cushing syndrome secondary to an inappropriate use of topical steroids, due to a misdiagnosis of scabies.

Total water intake and its contributors in infants and young children

2021 ◽  
pp. 1-32
Author(s):  
Jean-Pierre Chouraqui ◽  
Simon N. Thornton ◽  
Louise Seconda ◽  
Stavros A. Kavouras
Keyword(s):  
Young Children ◽  
Water Intake ◽  
Water Consumption ◽  
Consumption Pattern ◽  
Plain Water ◽  
Age Group ◽  
Total Water ◽  
Beverage Consumption ◽  
Infants And Young Children ◽  
Total Water Intake

Abstract Hydration is a particular concern for infants and young children due to their greater risk of dehydration. However, studies on their water intakes are scarce. The current survey aimed to analyze total water intake (TWI) in non-breastfed children aged 0.5-35 months compared to the adequate intake (AI) for the same age group set by the EFSA and to examine the different contributors to TWI as well as beverage consumption patterns. Nationally representative data from the Nutri-Bébé cross-sectional survey were used to assess food, beverage, and plain water consumption by age group over three non-consecutive days. With age, median TWI in 1,035 children increased from 732 to 1010 mL/d, without differences between sex, but with a great inter-individual variation, and the percentage of children who did not meet the AI increased from 10% to 88%. Median weight-related TWI decreased from 136.6 to 69.0 mL/kg/d. Among infants, 90% had a ratio of water/energy below the AI, similarly for about 75% of toddlers. Milk and milk products were the main contributors to TWI, while the part of plain water increased gradually to be 25% in the older toddlers, half of which was tap water. The beverage consumption pattern varied in types and timing, with little consumption of juices and sweetened beverages. Vegetables and fruits accounted for 20% of TWI after the age of 6 months. These initial results, showing strong discrepancies between actual and recommended water intakes in young children, should help identify ways to increase children’s water consumption.

scholarly journals The first experience of pneumovesicoscopic ureteral reimplantation in children under 2 years of age

2020 ◽  
Vol 24 (5) ◽  
pp. 303-306
Author(s):  
Sergey A. Karpachev ◽  
S. N. Zorkin ◽  
A. S. Gurskaya ◽  
A. O. Tarzyan ◽  
R. R. Bayazitov ◽  
...  
Keyword(s):  
Young Children ◽  
Small Volume ◽  
Limiting Factors ◽  
Age Group ◽  
Ureteral Reimplantation ◽  
Highly Qualified ◽  
Surgical Team ◽  
Surgical Interventions ◽  
Open Procedure ◽  
Procedure Duration

Actuality. To date, there are few publications focused on pneumovesicoscopic ureteral reimplantation in young children. The article is devoted to surgical interventions in this age group. Material and methods. Surgical interventions on small volume bladder have significant technical difficulties. The authors assessed potentials for performing pneumovesicoscopic ureteral reimplantation by the Cohen technique in 14 children under 2 with various obstructive uropathies. Results. In all children, surgical interventions were performed according to preoperative plans. There were no conversions to an open procedure. As it has been found out, patient’s age and bladder volume were not limiting factors for this type of intervention. Conclusion. The pneumovesicoscopic ureteral reimplantation in young children is a hi-tech procedure which requires a unique equipment and a highly qualified surgical team. To reduce the procedure duration, further experience and more information are needed.

scholarly journals PENGELOMPOKAN JUMLAH PENDUDUK BERDASARKAN KATEGORI USIA DENGAN METODE K-MEANS

2019 ◽  
Vol 2 (2) ◽  
pp. 166
Author(s):  
Sahat Sonang ◽  
Arifin Tua Purba ◽  
Ferri Ojak Imanuel Pardede
Keyword(s):  
Young Children ◽  
Human Resources ◽  
Data Processing ◽  
Early Adulthood ◽  
Age Groups ◽  
Early Adolescents ◽  
Age Group ◽  
Late Adolescents ◽  
Economic Level ◽  
The Government

Control of population is one of the tasks of the government in Indonesia. The increase and movement of population in each region makes a certain area to defeat changes in population surging, and this can affect the economic level of the area. This study aims to process the population of Pematangsiantar City in 2018 which is divided into age groups, namely: Toddlers, Young Children, Early Adolescents, Late Adolescents, Early Adolescents, Late Adulthood, Early Adulthood, Elderly, Late Elderly, and Upper Seniors. Data processing is done by using K-Means method clustering in accordance with the population of Pematangsiantar City per district. With this grouping, we can see that the number of population in each sub-district is based on each age group so that we can implement programs that are more appropriate in improving human resources.

scholarly journals Incidence of steroid modified tinea in pediatric age group at tertiary centre in North India

2021 ◽  
Vol 7 (5) ◽  
pp. 677
Author(s):  
Savita Chaudhary ◽  
Chandni Jain ◽  
Gaurav Paliwal ◽  
Priyanka Shukla
Keyword(s):  
Common Species ◽  
North India ◽  
Topical Steroids ◽  
Age Group ◽  
Pediatric Age ◽  
Atypical Form ◽  
Pediatric Age Group ◽  
Tertiary Centre ◽  
History Of ◽  
Common Variety

<p class="abstract"><strong>Background:</strong> Uncontrolled use and abuse of topical steroids has led to increase in number of cases of superficial dermatophytosis of skin, hair and nail in pediatric age group as well. Our study aimed to analyse epidemiological and microbiological profile of steroid modified tinea (SMT) in pediatric age group.</p><p class="abstract"><strong>Methods:</strong> Clinically diagnosed tinea childhood patients with history of usage of topical steroids in children were included in our study. Detailed history was taken and clinical examination along with KOH mount and culture was done.<strong></strong></p><p class="abstract"><strong>Results:</strong> 112 patients were clinically diagnosed as tinea out of which 61cases gave the history of topical steroids and were included in our study. Most common age group was 12-18 years with female:male of ratio approximately 3:1 and disseminated and atypical form was the most common variety. KOH mount was positive in 73.2% cases and culture was positive in 69.6% cases. Most common species found out to be <em>Tinea mentagrophytes</em> followed by <em>Tinea rubrum</em>. Among non-dermatophyte group, <em>Candida</em> was the commonest.</p><p class="abstract"><strong>Conclusions:</strong> There is rise in incidence of dermatophytosis, especially steroid modified, atypical and disseminated.</p>

scholarly journals Late-onset Congenital Adrenal Hyperplasia with Cushing Syndrome

2014 ◽  
Vol 53 (17) ◽  
pp. 1955-1959 ◽  
Author(s):  
Gurbuz Erdogan ◽  
Recai Pabuccu ◽  
Sibel Ertek ◽  
Shoshana Israel ◽  
Banu Yilmaz ◽  
...  
Keyword(s):  
Congenital Adrenal Hyperplasia ◽  
Cushing Syndrome ◽  
Late Onset ◽  
Adrenal Hyperplasia

Case 121: Familial Adrenocorticotropin-independent Macronodular Adrenal Hyperplasia Causing Cushing Syndrome

Radiology ◽  
2007 ◽  
Vol 244 (3) ◽  
pp. 923-926 ◽  
Author(s):  
Timothy D. Watson ◽  
Shital J. Patel ◽  
Peter M. Nardi
Keyword(s):  
Cushing Syndrome ◽  
Adrenal Hyperplasia

scholarly journals Mifepristone Treatment in Four Cases of Primary Bilateral Macronodular Adrenal Hyperplasia (BMAH)

2019 ◽  
Vol 104 (12) ◽  
pp. 6279-6290 ◽  
Author(s):  
Pejman Cohan ◽  
Honey E East ◽  
Sandi-Jo Galati ◽  
Jennifer U Mercado ◽  
Precious J Lim ◽  
...  
Keyword(s):  
Treatment Duration ◽  
Cushing Syndrome ◽  
Signs And Symptoms ◽  
Response Assessment ◽  
Common Adverse Event ◽  
Adrenal Hyperplasia ◽  
Significant Weight Loss ◽  
Rare Form ◽  
Unilateral Adrenalectomy ◽  
Medical Practices

ContextPrimary bilateral macronodular adrenal hyperplasia (BMAH) is a rare form of adrenal Cushing syndrome conventionally treated with adrenalectomy. Medical treatment is often reserved for patients not eligible for surgery. However, to date there have been few studies about the efficacy of mifepristone for the treatment of BMAH associated with hypercortisolism.ObjectiveTo describe a series of patients with hypercortisolism due to BMAH treated with mifepristone from multiple medical practices.DesignWe retrospectively assessed four patients treated with mifepristone for hypercortisolism due to BMAH who had either failed unilateral adrenalectomy, declined surgery, or were poor surgical candidates.ResultsMifepristone induced clinical improvement and remission of the signs and symptoms of hypercortisolism in all described patients with BMAH. The median treatment duration at the time of efficacy response assessment was 5 months (range: 3 to 18 months). Improvement in cardiometabolic parameters was observed as early as 2 weeks after treatment was started. All patients achieved improvements in glycemic control and hypertension and had significant weight loss. The most common adverse event observed with mifepristone therapy was fatigue. Increases in TSH level occurred in two patients.ConclusionMifepristone can be an effective medical alternative to surgery in patients with hypercortisolism due to BMAH.

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