scholarly journals Implant Treatment with 12-Year Follow-Up in a Patient with Severe Chronic Periodontitis: A Case Report and Literature Review

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Keisuke Seki ◽  
Yoshiyuki Hagiwara
Keyword(s):  
Periodontal Disease ◽  
Chronic Periodontitis ◽  
Case Reports ◽  
English Literature ◽  
Supportive Therapy ◽  
Periodontal Treatment ◽  
Periodontal Tissues ◽  
Severe Periodontitis ◽  
And Control ◽  
Implant Treatment

Tooth loss among adults is associated with progressive periodontitis. Implant prosthetic treatment has long been utilized in periodontal patients. Even when the implants are applied, ongoing management of periodontal disease and control of inflammation is necessary to maintain a healthy oral cavity. Lack of appropriate periodontal treatment can result in recurrence of periodontal disease during a maintenance period; loss of the supportive capacity of the periodontal tissues will increase the susceptibility of residual teeth to traumatic force. For this reason, it is worthwhile to improve oral function by applying implants as a fixed device. Here, we report that implant treatment in a patient with generalized severe chronic periodontitis helped maintain the periodontal and peri-implant tissue for a long term. We propose that initial periodontal treatment and ongoing supportive therapy can help maintain implants in patients with severe periodontitis. In addition, we reviewed case reports in the English literature so far.

scholarly journals A COMPARATIVE STUDY TO ASSES THE EFFICACY OF NANOBIO FUSION GEL AS AN ADJUNCT TO SCALING AND POLISHING IN CHRONIC PERIODONTITIS. - A CLINICAL STUDY

2020 ◽  
pp. 1-3
Author(s):  
Patil A. Veena ◽  
Ansari T. Sobia ◽  
Agarwal Priyanka ◽  
Ayesha Ayesha ◽  
Sultana Shahnaaz
Keyword(s):  
Periodontal Disease ◽  
Chronic Periodontitis ◽  
Antimicrobial Agents ◽  
Test Group ◽  
Controlled Clinical Trial ◽  
Pocket Depth ◽  
Antioxidant Power ◽  
Probing Pocket Depth ◽  
Significant Difference ◽  
And Control

Introduction: Various chemical agents such as nonsteroidal, anti-inflammatory drugs and antimicrobial agents has gained popularity in treatment of periodontal disease but simultaneously lead to condition such as drug resistance and drug allergy. Hence , the topical application of herbal agents such as propolis, aloevera, green tea extracts, Neem reduces the potency and effectiveness to prevent progression of periodontal disease. NanoBioFusion(NBF)gel contains the natural antioxidant power of propolis,vit C,vit E which allows the ultrafine antioxidant to surpase the moist intraoral environment to enter the cells and rejuvenate,revitalize,support,protect and optimize gum and soft oral tissue.Hence the present study is aimed to evaluate the clinical effect of locally delivered NBF gel as an adjunctive therapy to scaling and polishing in the treatment of Periodontitis. Materials and Methods: Chronic Periodontitis patients with 40 sites and probing pocket depth (PD) between 5 and 7 mm were selected in a randomized controlled clinical trial. SRP was performed in both control and test group followed by NBF gel application in 40 sites. The plaque index, gingival index and probing Pocket depth,were recorded at baseline, 6 weeks, and 3 months.The statistical analysis with paired t‑test was used to compare the test and control sites. Results: From baseline to a period of 3 months, a statistically significant difference was seen between both groups for Pocket probing depth and from baseline to 6 weeks the mean GI and PI score have a statistically significant result was obtained(P=0.01& 0.00). Conclusions: Locally delivered NBF gel exhibited a significant improvement compared with SRP alone in chronic periodontitis.

scholarly journals EVALUATION OF SALIVARY HEPATOCYTE GROWTH FACTOR LEVELS IN CHRONIC PERIODONTITIS PATIENTS BEFORE AND AFTER NON-SURGICAL PERIODONTAL TREATMENT

2020 ◽  
pp. 8-10
Author(s):  
Madhavi T ◽  
Mathew John ◽  
Bindu Rachel Thomas ◽  
Sabari Chandramohan ◽  
Aswathy S ◽  
...  
Keyword(s):  
Growth Factor ◽  
Hepatocyte Growth Factor ◽  
Chronic Periodontitis ◽  
Periodontal Treatment ◽  
Periodontal Tissues ◽  
Whole Saliva ◽  
Before And After ◽  
Unstimulated Whole Saliva ◽  
Relationship Of ◽  
Hepatocyte Growth

Hepatocyte Growth Factor (HGF) or Scatter Factor (SF) is a growth factor which restrains the reconstruction of profound periodontal tissues. The study estimated the salivary HGF levels in unstimulated whole saliva in chronic periodontitis patients prior to treatment and also at 2nd and 6th week after non-surgical periodontal treatment and also aimed to determine the relationship of salivary HGF levels with the clinical periodontal parameters. This was a prospective-analytical study which included 45 subjects with chronic periodontitis. The highest mean concentration of HGF was obtained at the baseline and the lowest mean HGF concentration was obtained at the 6th week. There was significant decrease in the salivary HGF levels among the patients subsequent to scaling and root planing. Moreover the salivary HGF levels indicated a positive correlation with the clinical parameters at the sixth week. The above results propose that salivary HGF levels could be utilized as a biomarker for checking the response to periodontal treatment in chronic periodontitis patients.

scholarly journals Effect of non-surgical periodontal treatment on serum albumin levels in patients with chronic periodontitis

2018 ◽  
Vol 10 (1) ◽  
pp. 18-23
Author(s):  
Adileh Shirmohammadi ◽  
Masoumeh Faramarzi ◽  
Ashkan Salari ◽  
Mehrnoosh Sadighi Shamami ◽  
Amir Reza Babaloo ◽  
...  
Keyword(s):  
Periodontal Disease ◽  
Serum Albumin ◽  
Chronic Periodontitis ◽  
Periodontal Diseases ◽  
Statistical Significance ◽  
Serum Levels ◽  
T Test ◽  
Periodontal Treatment ◽  
Case Group ◽  
Clinical Parameters

Background. Albumin is a protein whose serum levels decrease in inflammatory conditions such as periodontal diseases. This study was undertaken to evaluate changes in serum albumin levels in patients with and without periodontal diseases prior and subsequent to non-surgical periodontal treatment and its relationship with clinical parameters of periodontal disease.Methods. Twenty patients diagnosed as having chronic periodontitis and 20 periodontally healthy subjects, referring to Tabriz Faculty of Dentistry, were selected. Serum albumin levels and clinical variables of periodontal disease (probing pocket depth, gingival index, bleeding index, clinical attachment level and plaque index) were determined before treatment and three months subsequent to non-surgical periodontal treatment. Data were subjected to descriptive statistical analyses (mean ± SD). Serum levels of albumin and clinical parameters were compared between the two groups with independent-samples t-test. Paired-samples t-test was applied to compare the variables before and after treatment in the case group. Statistical significance was defined at P<0.05.Results. The mean serum albumin level of chronic periodontitis patients (3.62±0.11 mg/dL) exhibited a significantly lower value compared to subjects who were periodontally healthy (4.17±0.29 mg/dL), with the serum albumin levels increasing significantly three months postoperatively (3.78±0.33 mg/dL), approaching the level in subjects who were periodontally healthy (P<0.05).Conclusion. Decreases and increases in serum albumin levels under the effect of periodontal disease and its treatment indi-cated an inverse relationship between the albumin levels of serum and chronic periodontitis.

scholarly journals Comparative evaluation of expression of VEGF (vascular endothelial growth factors) in periodontal tissues of healthy, chronic and aggressive periodontitis patients: an immunohistochemical study

2020 ◽  
Vol 9 (1) ◽  
pp. 784-788
Keyword(s):  
Growth Factors ◽  
Periodontal Disease ◽  
Chronic Periodontitis ◽  
Periodontal Diseases ◽  
Aggressive Periodontitis ◽  
Control Group ◽  
Vascular Endothelial ◽  
Healthy Controls ◽  
Periodontal Tissues ◽  
Inflammatory Status

Periodontitis is a chronic inflammatory disease of the vascularized supporting tissues of the teeth. Angiogenesis (neovascularization) is the budding of new capillaries and is thought to be an essential process in the development of chronic inflammatory diseases. Inflamed tissues (such as gingiva coincident in periodontal disease) have evidence of enhanced expression of inflammatory mediators, many of which can promote angiogenesis. Of the various cytokines and growth factors that are involved in angiogenesis, the most potent agent that acts specifically on vascular epithelium is Vascular Endothelial Growth Factor. Even though angiogenesis is a prominent feature of both inflammation and healing, information about its role in periodontal lesions is limited. Hence the aim of the present study was the immunohistochemical evaluation of the expression of VEGF in the gingival tissues of chronic and aggressive periodontitis patients compared to the healthy controls. The present study was carried out in a total of 45 subjects with age range of 18-55 years, reporting to the Department of Periodontology, Rajarajeswari Dental College and Hospital, Bangalore. Gingival tissue samples were collected from all the 45 subjects and categorized into three groups based on their clinical findings as follows: Group 1 (Healthy), Group II (Chronic Periodontitis), Group III (Aggressive Periodontitis). Following sample collection, immunohistochemical staining of tissues was carried out and evaluation was done to compare the grades of expression of VEGF in the three groups. The expression of VEGF in blood vessels was also quantitatively evaluated. The results were statistically analyzed using Kruskal Wallis ANOVA and Mann Whitney test. There was a statistically significant higher expression of VEGF in both chronic periodontitis and aggressive periodontitis group as compared to the control group. Aggressive periodontitis cases showed higher grades of expression of VEGF compared to the chronic periodontitis cases and healthy controls. However, the difference in expression of VEGF was not statistically significant between the two forms of periodontitis. The presence of VEGF in both chronic and aggressive periodontitis clearly indicates the potent role played by VEGF as an inflammatory agent in the initiation and progression of periodontal diseases. Thus, VEGF might be used as a potential vascular marker for the assessment of severity and inflammatory status in periodontal disease.

scholarly journals Clindamycin as an Alternative Option in Optimizing Periodontal Therapy

Antibiotics ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 814
Author(s):  
Ionut Luchian ◽  
Ancuta Goriuc ◽  
Maria Alexandra Martu ◽  
Mihai Covasa
Keyword(s):  
Periodontal Disease ◽  
Tooth Loss ◽  
Periodontal Treatment ◽  
Host Immune System ◽  
Antibiotic Administration ◽  
Bacteriostatic Effect ◽  
Oral Biofilm ◽  
Bacterial Proteins ◽  
Periodontal Tissues ◽  
Degrees Of Severity

Periodontal disease is an oral infectious and inflammatory disease caused by microorganisms that determine the host-mediated destruction of soft and hard periodontal tissues, which ultimately leads to tooth loss. Periodontitis affects a large part of the population, with various degrees of severity. Treatment consists of etiologic therapy: the removal of biofilm through mechanical debridement plus microbial elimination by supplementary measures. Antibiotic administration, either systemically or through local delivery, has been shown to improve clinical outcomes after mechanical periodontal treatment. Clindamycin is a lincosamide with a broad spectrum, being active against aerobic, anaerobic, and β-lactamase-producing bacteria. This antibiotic offers several advantages and some disadvantages and has been used in periodontal treatment both systemically and locally with various degrees of success. Among the properties that recommend it for periodontal treatment is the bacteriostatic effect, the inhibition of bacterial proteins synthesis, the enhancement of neutrophil chemotaxis, phagocytosis and the oxidative burst–oxidative stress storm. Furthermore, it is easily absorbed at the level of oral tissues in a considerable amount. This substantial tissue penetration, especially inside the bone, is synergistic with a stimulating effect on the host immune system. The aim of this review is to explore the applicability of this antibiotic agent and to evaluate its antimicrobial potential and limitations at the level of the oral biofilm associated with periodontal disease.

scholarly journals Serum interleukin-17 (IL-17) in chronic periodontitis patients

2017 ◽  
Vol 29 (3) ◽  
Author(s):  
Erry Mochamad Arief ◽  
Marina Binti Mubin ◽  
Siti Lailatul Akmar Zainuddin ◽  
Nurul Asma Abdullah ◽  
Basaruddin Ahmad
Keyword(s):  
Periodontal Disease ◽  
Chronic Periodontitis ◽  
Healthy Subjects ◽  
Elisa Test ◽  
Treatment Center ◽  
Interleukin 17 ◽  
Chronic Periodontal Disease ◽  
Screening Assessment ◽  
And Control ◽  
Control Study

Introduction: Explorations into the periodontal medicine relationship have discovered interleukin-17 (IL-17) cytokine as one of the pro-inflammatory mediators that play a crucial role in the initiation and progression of the chronic periodontal disease. This case and control study aimed to compare the serum IL-17 concentration between chronic periodontitis and healthy subjects and to assess the relationship between the IL-17 serum and the clinical periodontal parameters in chronic periodontitis patients. Methods: This study was a case-control study. The subjects were selected using purposive sampling method. The periodontal screening assessment in the Family Treatment Center and Postgraduate Dental Clinic, Universiti Sains Malaysia Hospital. A total of 55 samples who fit with the inclusion and exclusion study criteria of full-mouth clinical periodontal records together with blood serums were obtained from 28 chronic periodontitis patients and from 27 healthy subjects. The concentration of IL-17 cytokine in serum was measured using ELISA test. Results: Subjects with periodontal disease presented significantly worse clinical parameters (p<0.001) compared to control. The level of serum IL-17 concentration was significantly higher (p=0.026) in chronic periodontitis subjects 3.6 (1.03) pg/mL compared to the control 3.1 (0.70) pg/mL. Conclusions: There was no correlation between the level of IL-17 concentration in the serum and clinical periodontal parameters.

scholarly journals AVALIAÇÃO DO USO DO CHÁ VERDE (CAMELLIA SINENSIS) COMO COADJUVANTE NO TRATAMENTO E CONTROLE DA DOENÇA PERIODONTAL: REVISÃO INTEGRATIVA

2021 ◽  
Vol 10 (12) ◽  
pp. 1-21
Author(s):  
Otávio Augusto Pacheco VITÓRIA ◽  
Juliano Milanezi de ALMEIDA ◽  
Vivian Cristina Noronha NOVAES
Keyword(s):  
Periodontal Disease ◽  
Green Tea ◽  
Camellia Sinensis ◽  
Case Reports ◽  
Cochrane Library ◽  
Controlled Trials ◽  
Scaling And Root Planing ◽  
Randomized Controlled ◽  
And Control

Terapias coadjuvantes ao tratamento convencional da periodontite têm sido sugeridas para otimizar os resultados terapêuticos, sendo que o chá verde tem sido proposto por apresentar propriedades benéficas ao tratamento periodontal. Nesse contexto, o objetivo desta revisão integrativa foi avaliar se o uso do chá verde é eficaz no tratamento e controle da periodontite. Para isso, foi realizado um levantamento bibliográfico nas bases de dados PubMed, Lilacs e Cochrane Library, com os descritores green tea, periodontal disease, Camellia sinensis e periodontitis. Foram selecionados artigos na língua inglesa publicados nos últimos 10 anos em que o chá verde deveria ser obrigatoriamente empregado como uma conduta terapêutica e incluídos estudos clínicos randomizados controlados e revisões sistemáticas. Foram excluídos ensaios pré-clínicos, relato de caso clínico, série de relatos clínicos, estudos epidemiológicos, editoriais, opiniões de especialistas, estudo piloto, revisões de literatura, pesquisas com resultados inconcludentes e estudos in-vitro. A busca resultou em 450 artigos dos quais, após aplicação dos critérios de inclusão e exclusão, selecionaram-se 10 artigos, sendo 8 ensaios randomizados controlados e 2 revisões sistemáticas com meta-análise. 6 artigos avaliaram a efetividade do chá verde como colutório oral demonstrando redução da inflamação e do acúmulo de placa bacteriana, 3 estudos associaram o chá verde a raspagem e alisamento radicular, demonstrando diminuição da profundidade, sangramento a sondagem e redução do quadro inflamatório e 1 estudo avaliou a ingestão sistêmica, demonstrando redução na profundidade de sondagem e sangramento. Dessa forma, podemos concluir que o chá verde é eficaz como terapia coadjuvante no tratamento e controle da periodontite. Quando associado à raspagem e ao alisamento radicular e como colutório oral, apresentam-se resultados mais satisfatórios que na forma de ingestão oral.   ASSESSMENT OF GREEN TEA (CAMELLIA SINENSIS) USED AS AN ADJUNCT TO TREATMENT AND CONTROL OF PERIODONTAL DISEASE: INTEGRATIVE REVIEW   Adjunct therapies to conventional treatment for periodontitis have been suggested to optimize therapeutic results; green tea has been suggested because it presents beneficial properties for periodontal treatment. In this context, this integrative review aims at assessing the effectiveness of green tea for periodontitis treatment and control. Thus, bibliographic research was carried out in PubMed, LILACS, and Cochrane Library databases, using the words green tea, periodontal disease, Camelliasinensis, and periodontitis as keywords. Articles in English language issued in the last 10 years were screened, in which green tea was imperatively used as a therapeutic approach and included randomized controlled trials and systematic reviews. Pre-clinical trials, clinical case reports, series of case reports, epidemiological studies, editorials, expert opinions, pilot study, literature review, researches with inconclusive results, and in-vitro studies were excluded. The search resulted in 450 articles in which, after applying inclusion and exclusion criteria, 10 articles were screened, being 10 articles, 8 randomized controlled trials, and 2 systemic reviews and meta-analysis. 6 articles assessed the effectiveness of green tea as mouthwash and presenting a reduction either in inflammation and the accumulation of bacterial plaque, 3 studies associated green tea to scaling and root planing, indicating a decrease in the depth, bleeding when drilling, and reduction in the inflammatory process, 1 study assessed the systemic intake, indicating a reduction in drilling depth and bleeding. Thus, we can conclude that green tea is efficient as adjuvant therapy to the treatment and control of periodontitis. When associated with scaling and root planing, and used as a mouthwash, the results were more satisfactory when it was used as a mouthwash than when it was ingested.   Keywords: Tea. Camelliasinensis. Periodontal Diseases. Periodontology.

scholarly journals Evaluation the Effects of Led Photo-Activated Disinfection on Periodontal Clinical Parameters in Patients with Chronic Periodontitis

2016 ◽  
Vol 20 (1) ◽  
pp. 29-32
Author(s):  
Alexandra Martu Maria ◽  
Irina-Georgeta Ursarescu ◽  
Sorina Solomon ◽  
Liliana Foia
Keyword(s):  
Periodontal Disease ◽  
Chronic Periodontitis ◽  
Conventional Therapy ◽  
Control Group ◽  
Study Group ◽  
Clinical Parameters ◽  
Systemic Diseases ◽  
And Control ◽  
Tolonium Chloride ◽  
Post Therapy

SummaryThe purpose of the study was to assess the effects of LED-PAD and tolonium chloride on periodontal clinical parameters in chronic periodontitis. Materials and Methods: The study was conducted on patients with chronic periodontitis, divided in 2 groups (study group and control group of patients who, besides the conventional therapy measures, also received PAD therapy). The periodontal clinical parameters were registered at baseline and after 3 months. Results and Discussions: The post-therapy evaluation revealed significantly improved results of periodontal clinical parameters in the study group, when compared to the control group. Our results support the literature studies conducted on chronic periodontitis patients but without any systemic diseases. Conclusion: The PAD disinfection determined a significant improvement for the periodontal clinical parameters in patients with periodontal disease.

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