scholarly journals Isoniazid-Induced Acute Psychosis in a Patient with Pleural Tuberculosis

2019 ◽  
Vol 2019 ◽  
pp. 1-3
Author(s):  
Joana Gomes ◽  
Diana Durães ◽  
André Sousa ◽  
Hugo Afonso

Tuberculosis is one of the top 10 causes of death and the leading cause from a single infectious agent (above HIV/AIDS). Isoniazid is highly bactericidal against replicating tubercle bacilli and is a component of all antituberculous chemotherapeutic regimens currently recommended by the World Health Organization (WHO). Several neuropsychiatric adverse effects, following both therapeutic and overdose use of isoniazid, have been described and isoniazid-induced psychosis, although uncommon, has been reported in the literature. We describe the case of a 21-year-old black woman, with no prior psychiatric history, who developed a psychotic episode four days after she was started on isoniazid. This case highlights psychosis arising as a possible adverse effect of isoniazid and the importance of remaining vigilant when antituberculous therapy is started.

Author(s):  
Kumar Abhishek ◽  
M. P Singh ◽  
Md. Sadik Hussain

<p>Tuberculosis (TB) has been one of the top ten causes of death in the world. As per the World Health Organization (WHO) around 1.8 million people have died due to tuberculosis in 2015. This paper aims to investigate the spatial and temporal variations in TB incident in South Asia (India, Bangladesh, Pakistan, Maldives, Nepal, and Sri-Lanka). Asia had been counted for the largest number of new TB cases in 2015. The paper underlines and relates the relationship between various features like gender, age, location, occurrence, and mortality due to TB in these countries for the period 1993-2012.</p>


2021 ◽  
Vol 7 (1) ◽  
pp. 24-32
Author(s):  
Semen Kireev ◽  
I. Popov ◽  
A. Ban'kovskiy ◽  
E. Litvinenko ◽  
E. Surova

At the end of 2019, an outbreak of a new coronavirus infection occurred in the People's Re-public of China with an epicenter in the city of Wuhan (Hubei province). On February 11, 2020, the World Health Organization has assigned the official name of the infection caused by the new coronavirus - COVID-19 ("Coronavirus disease2019"). On February 11, 2020, the International Committee on Virus Taxonomy gave the official name to the infectious agent - SARS-CoV-2.Since the end of January 2020, cases of COVID-19 have begun to be registered in many coun-tries of the world, mainly associated with travel to the PRC. At the end of February 2020, the epidemiological situation with COVID-19 in South Korea, Iran and Italy sharply worsened, which subsequently led to a significant increase in the number of cases in other countries of the world associated with travel to these countries, incl. and in Russia. The World Health Organiza-tion announced the COVID-19 pandemic on 11 March 2020, and the pandemic's challenge to the world will remain so as long as people are not immune to it.The Regional Director of the World Health Organization Takeshi Kasai, on the basis of an epidemiological analysis, reports that the spread of coronavirus infection COVID-19 in July-August 2020 occurred mainly among people under 50 years old, and they often did not even know about it, because they had mild or no symptoms. In the future, these people then infect older people who are more difficult to tolerate COVID-19. And we need to redouble our efforts to prevent the spread of the virus in vulnerable communities.


Author(s):  
Cristina Bragança ◽  
Inês Gonçalves ◽  
Luísa Guerreiro ◽  
Maria Janeiro

AbstractTuberculosis is an infectious disease caused by Mycobacterium tuberculosis. According to data from the World Health Organization, this disease remains one of the leading causes of death worldwide. Although it most commonly affects the lungs, tuberculosis can compromise any organ. The present study reports a rare case of vulvar tuberculosis in a postmenopausal woman with a history of asymptomatic pulmonary and pleural tuberculosis, with no prior documented contact with the bacillus. Diagnosis was based on vulvar lesion biopsies, with histological findings suggestive of infection and isolation of M. tuberculosis by microbiological culture and polymerase chain reaction (PCR) essays. The lesions reverted to normal after tuberculostatic therapy.


2004 ◽  
Vol 26 (2) ◽  
pp. 11-14
Author(s):  
Richard W. Titball

Yersinia pestis is the aetiological agent of plague, a disease that has a place in history as one the major causes of death from the 14th to the 17th Centuries1. It is estimated that, during the Black Death pandemic, approximately 30% of the population of Europe died of plague, and so great in number were the corpses that, in many parts of Europe, the dead were placed in burial pits rather than receiving individual burials. Y. pestis has also been responsible for two other pandemics of disease. The first of these, the Justinian plague, occurred during the 1st Century. The third pandemic occurred during the latter part of the 19th Century and was confined mainly to South-East Asia1. Even today, several thousand cases of plague are reported to the World Health Organization each year, mainly from South-East Asia, the southwestern parts of the USA, Madagascar and Africa.


2021 ◽  
Vol 5 (6) ◽  
pp. 241-243
Author(s):  
Ferhan Soyuer

Physical inactivity constitutes the basis of diseases that reduce life duration and quality and rank first among the causes of death in the world. Worldwide, it has been determined that 23 % of adults aged 18 and over are not active enough. According to the World Health Organization, sedentary life is among the main risk factors for deaths from non-communicable diseases worldwide and causes approximately 3.2 million deaths per year. For this reason, the issue of reducing inactivity has gained importance in the world today. As a solution, it is thought that increasing physical activity requires not only individual but also community-specific, multi-sectoral, multi-disciplinary and culturally appropriate approaches.


Author(s):  
Dorota Lasota ◽  
Witold Pawłowski ◽  
Paweł Krajewski ◽  
Anna Staniszewska ◽  
Krzysztof Goniewicz ◽  
...  

Introduction: Suicide is one of the most frequent causes of death. According to the World Health Organization (WHO), each year, over eight hundred thousand people worldwide die as a result of suicide. The most common risk factors for suicide are depressive disorders and alcohol dependence. Alcohol can directly influence a decision about suicide, or be a factor facilitating this decision. The aim of the study was to analyse the seasonality of suicides among persons under the influence of alcohol. Material and Methods: Data for analysis were obtained from the Department of Forensic Medicine (DFM) of the Medical University of Warsaw. A retrospective analysis was performed on 317 victims of suicides by hanging, those which were entered into the registry of deaths kept by the DFM in the years 2009–2013. The analysis took into account the age and sex of victims, initial cause of death, date of post-mortem examination, autopsy result and alcohol concentration in the blood or muscles of the victims. Statistical analysis was performed using IBM SPSS Statistics version 20. Results: In the analysis, a spring peak of suicides was found for men, and an autumn peak was revealed for women. In addition, a significant correlation was observed between the age of victims and the concentration of alcohol; the older the victims, the higher the alcohol concentration. However, this correlation was reported only in the spring months. Conclusions: The results of the analysis seem to be consistent with seasonal patterns observed in other studies, and they indicate the occurrence of suicide seasonality. In order to improve the strategies of suicide prevention, it is necessary to identify factors which are related to the seasonal variation of suicidal behaviours, as well as to gain knowledge about the mechanisms behind this phenomenon.


Author(s):  
Annalisa Guarini ◽  
Miguel Pérez Pereira ◽  
Anneloes van Baar ◽  
Alessandra Sansavini

As indicated by the World Health Organization, preterm birth is a relevant public health issue, being one of the leading causes of death in children under five years of age [...]


2018 ◽  
Vol 16 (2) ◽  
Author(s):  
Deny Febriyanto ◽  
Yogiek Indra Kurniawan

Tuberculosis (TB) is an infectious disease caused by mycobacteria, especially Mycobacterium tuberculosis. TB disease remains one of the threats, especially in a country with low and middle economic levels. According to the World Health Organization (WHO) TB disease became one of the biggest causes of death in the world. Indonesia ranks second with the largest number of TB cases in the world. In addition, there are some symptoms and factors that can cause a person affected by TB disease. For the treatment of TB disease can be done intensively, but it takes a long time. Research in the diagnosis of disease with classification techniques using C4.5 algorithm has been done by several previous researchers and get good results. Therefore, in this research will be predicted TB disease using C4.5 algorithm. The C4.5 algorithm is chosen because it is very easy to interpret, fast, and has high precision accuracy. The results of this study is an application that can help people to make the diagnosis of TB disease from an early age.


2017 ◽  
Vol 145 (7) ◽  
pp. 1368-1373
Author(s):  
M. C. PAYEN ◽  
J. P. VAN VOOREN ◽  
O. VANDENBERG ◽  
N. CLUMECK ◽  
S. DE WIT

SUMMARYTuberculosis (TB) remains a threat to public health and is the second cause of death due to a single infectious agent after HIV/AIDS. The worldwide distribution of TB is heterogeneous. The incidence is decreasing in most high-income regions, but the situation remains worrying in many parts of the world. The emergence of Mycobacterium tuberculosis strains resistant to key agents used in treatment (rifampin and isoniazid) contributes to TB transmission around the world. To achieve TB elimination, both high and low endemic countries must upscale their efforts to decrease disease transmission and improve cure rates. Management of drug-resistant TB is of particular importance. In this paper, we discuss the different models of care of multidrug-resistant TB (MDR-TB), the ethical considerations and the specific constraints present in high income countries. The management model chosen by the Belgian TB specialists in accordance with public health authorities as well as building of a specific MDR/XDR-TB isolation unit are also discussed.


2020 ◽  
Vol 50 (3) ◽  
pp. 232-234
Author(s):  
Roshni Pillay ◽  
Balram Rathish ◽  
Geetha M Philips ◽  
R Anil Kumar ◽  
Abin Francis

The leading causes of death in the world are cardiovascular disease (CVD) and stroke according to the World Health Organization, as is also the case in India. There is also a high prevalence of major conventional risk factors in India, where 18.3%, 9.0% and 14.1% of adults are diagnosed with hypertension, diabetes and smoking, respectively. The aim of the present study was to look at the risk of CVD among doctors in our country using a validated tool developed by the National Health Service (NHS) in the UK, the QRISK3 calculator.


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