scholarly journals Salivary 1,5-Anhydroglucitol and Vitamin Levels in Relation to Caries Risk in Children

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Sadatullah Syed ◽  
Syed M. Yassin ◽  
Ali A. Dawasaz ◽  
Mohammed Amanullah ◽  
Ibrahim Alshahrani ◽  
...  
Keyword(s):  
Negative Correlation ◽  
Assessment Tool ◽  
Risk Groups ◽  
Pediatric Dentistry ◽  
Healthy Children ◽  
Caries Risk ◽  
Strong Negative Correlation ◽  
Caries Activity ◽  
High Caries Risk ◽  
Caries Assessment

The objective of this study was to evaluate the association between salivary 1,5-anhydroglucitol (AG), vitamins A (VA), C (VC), and E (VE), and caries risk in children. 100 healthy children aged between 6 and 13 years were divided into two equal groups of caries-free (DMFS/dmfs=0) and caries active (DMFS/dmfs>3). Unstimulated midmorning saliva was collected from all the children and the levels of salivary AG and vitamins A, C, and E were measured. Caries risk assessment was done using American Academy of Pediatric Dentistry Caries Assessment Tool. Analysis of salivary AG and vitamins was performed using a commercially available ELISA kit. Low levels of AG were present in caries active and high caries risk groups compared to caries-free and low/medium caries risk groups. This difference is statistically significant (p < 0.05). A strong negative correlation between AG and caries activity was observed in the caries active group. VA was not related to caries activity, while VC and VE displayed a statistically significant correlation (p < 0.05). Similarly, a strong negative correlation was observed between the levels of AG and high caries risk group. Salivary AG, VC, and VE together are related to caries risk in caries active children. These salivary parameters can act as indicator of caries status in children.

A CAMBRA Model For High Caries Risk Indian Children: A Pragmatic Comprehensive Tailored Intervention

2016 ◽  
Vol 40 (1) ◽  
pp. 36-43 ◽  
Author(s):  
Krishan Gauba ◽  
Ashima Goyal ◽  
Neeti Mittal
Keyword(s):  
Pediatric Dentistry ◽  
Primary Outcome Measure ◽  
Secondary Outcome ◽  
Healthy Children ◽  
Caries Risk ◽  
Indian Children ◽  
Carious Lesions ◽  
High Caries Risk ◽  
Set Up

Objective: To evaluate a CAMBRA based therapeutic and preventive model for high caries risk children in a pediatric dentistry clinic set-up. Study design: A total of 100 systemically healthy children aged 4–8 years with dmft/DMFT ≥5 and/or ≤20% magnitude of cariogram sector ‘chance to avoid new cavities’ were enrolled. The program comprised of following components i.e. caries risk assessment, customized preventive interventions (Motivational interviewing and counseling, oral prophylaxis, fluoride varnish, fissure sealants) and restorative procedures. The recall intervals were scheduled on the basis of caries risk i.e. every 1 month (≤40% chance to avoid new cavities) and 3 months (≥41% chance to avoid new cavities). The primary outcome measure was ‘new carious lesions' at 12 months following achievement of ‘termination levels' i.e. ≥41% magnitude of ‘chance to avoid new cavities.' The secondary outcome measures were changes in cariogram parameters at termination and duration needed to achieve termination levels. Results: The program showed 97% success rate as 3/100 subjects developed new carious lesions at 12 months follow up. Highly significant (p&lt;0.001) favorable shift was achieved in cariogram parameters at termination. Termination levels were achieved in 2.71±4.854 months. Conclusions: The present CAMBRA based program with customized intervention and recall schedules showed favorable results.

scholarly journals Caries risk estimation in children regarding values of saliva buffer system components and carboanhydrase activity

2008 ◽  
Vol 65 (9) ◽  
pp. 676-680
Author(s):  
Dusan Surdilovic ◽  
Ivana Stojanovic ◽  
Mirjana Apostolovic
Keyword(s):  
Phosphate Buffer ◽  
Ph Value ◽  
Risk Estimation ◽  
Risk Groups ◽  
Buffer System ◽  
Caries Risk ◽  
High Caries Risk ◽  
Two Samples ◽  
Important Marker

Background/Aim. One of the preconditions for efficacious systematic reduction of caries prevalence and prophylaxis is the determination of risks of this disease appearance. The aim of this study was to prove the significance of salivary carboanhydrase activity determination in estimation of caries risk in children. Methods. The study included 123 children of average age of 13.4?0.3 years and permanent dentition. The children were divided into two groups according to caries risk (low and high caries risk groups). Two samples of saliva - unstimulated and stimulated one were taken from each child. Salivary carboanhydrase activity, as well as pH value, bicarbonate and phosphate buffer levels were estimated in both group of saliva samples. Results. The investigation showed significantly higher carboanhydrase activity (p < 0.001) in both saliva samples in low caries risk group compared to high caries risk one. In children with low caries risk, both unstimulated and stimulated saliva show significantly higher bicarbonate and phosphate buffer concentrations (p < 0.001), as well as pH values. Conclusion. The lower caries incidence could be expected in children with high carboanhydrase activity and higher salivary buffer system parameters levels. The presented results suggest that salivary carboanhydrase activity represents the important marker of individual susceptibility for caries appearance in children.

Success of Two Caries Risk Assessment Tools in Children: A Pilot Study With a 3-Year Follow-Up

2019 ◽  
Vol 40 (4) ◽  
pp. 317-320
Author(s):  
Elif Kuru ◽  
Ece Eden
Keyword(s):  
Risk Assessment ◽  
Preschool Children ◽  
Dental Caries ◽  
Dietary Habits ◽  
Assessment Tool ◽  
Systemic Disease ◽  
Risk Groups ◽  
Assessment Tools ◽  
Caries Risk ◽  
Caries Risk Assessment

Caries risk is defined as the dental caries probability under the individual bacteriological environment, dietary habits, and environmental factors. Assessment of caries risk plays a major role in the prevention of dental caries. The aim of this study was to compare the effectiveness of two different caries risk assessment methods on caries-free preschool children. A sample of 90 caries-free 4- to 6-year-old children were selected from 400 preschool children. The selection was limited to children who had no dental caries, visible plaque, and systemic disease. American Academy of Pediatric Dentistry’s Caries Risk Assessment Tool (CAT) and Clinpro Cario L-Pop (CCLP; 3M ESPE, Germany) were used to categorize children into caries risk groups. Children were classified as being in high-, medium-, or low-risk groups by two methods. Determining risk factors according to CAT were examined. The compliance among the two methods was evaluated. Sixty-eight children were reevaluated intraorally after 3 years. The compliance between CAT and CCLP was sought using Kappa test. Statistical evaluation revealed moderate compliance among methods at baseline. The three most determinant factors in the high-risk group according to CAT were no topical fluoride exposure, no use of dental services, and active caries in mother. CAT is found statistically more successful than CCLP in predicting caries risk 3 years later. Caries risk assessment is effective to predict future caries and can be helpful for the clinician to choose the right tailor-made caries prevention plans.

Pit and Fissure Sealants: An Unused Caries Prevention Tool

2010 ◽  
Vol 4 (1) ◽  
pp. 1-6 ◽  
Author(s):  
CM Marya ◽  
Hind Pal Bhatia ◽  
P Gupta ◽  
S Dhingra ◽  
S Kataria ◽  
...  
Keyword(s):  
Material Selection ◽  
Risk Groups ◽  
Permanent Teeth ◽  
Caries Risk ◽  
Fissure Sealants ◽  
Retention Capacity ◽  
Pit And Fissure Sealants ◽  
High Caries Risk ◽  
Occlusal Surfaces ◽  
History Of

ABSTRACT Pit and fissure sealants along with fluoridation and good oral hygiene is an important tool for the prevention of dental caries in children and adolescents. RECOMMENDATIONS The following recommendations are based on the evidence gathered: 1. Sealants should be placed on all permanent teeth without cavitation (i.e., teeth that are free of caries, teeth that have deep pit and fissure morphology, teeth with “sticky” fissures or teeth with stained grooves) as soon after eruption as isolation can be achieved. 2. Sealants should not be placed on partially erupted teeth or teeth with cavitation or caries of the dentin. 3. Sealants should be placed on the primary molars of children who are susceptible to caries (i.e., those with a history of caries). 4. Sealants should be placed on first and second molars within 4 years after eruption. 5. Resin-based sealants should be preferred, until such time as glass ionomer cements with better retention capacity are developed. 6. Sealants should be placed as part of an overall prevention strategy based on assessment of caries risk. Sealing is a recommended procedure to prevent caries of the occlusal surfaces of permanent molars. Though the effectiveness of sealants is obvious at high caries risk groups there is still some degree of latitudein operators preference for sealant placementand material selection.

Psoriasis and metabolic syndrome: comorbidity mechanisms

2019 ◽  
Vol 1 (7) ◽  
pp. 34-38
Author(s):  
E. V. Dontsova ◽  
O. Yu. Olisova ◽  
L. S. Kruglova
Keyword(s):  
Metabolic Syndrome ◽  
Negative Correlation ◽  
Inflammatory Cytokine ◽  
Antioxidant Ability ◽  
Weak Correlation ◽  
Strong Negative Correlation ◽  
The Metabolic Syndrome ◽  
Diagnostic Signs ◽  
Weak Negative Correlation ◽  
Correlation Link

Objectives: to study communications of separate components of the metabolic syndrome (MS) and immune and oxidative characteristics of patients with psoriasis in combination with MS. Methods. The research included 312 patients with psoriasis having diagnostic signs of a metabolic syndrome. Biochemical and immunological researches were conducted by means of immunofermental and immunokhemilyuminestsentny analyses. Results. At patients with psoriasis at a combination to MS abdominal obesity, a giperleptinemiya, insulin resistance, high oxidizing potential and hyperactivity of interleukins (ILS) -1β,-6,-8, a factor of a necrosis of tumors an alpha (FNO-α), interferon scale (INF-γ) are noted. the waist circle’ is characteristic direct weak correlation with the pro-inflammatory tsitokina oxidized by lipoproteins of blood (LDL-ok) and with the general oxidizing ability of blood (OOS), weak negative correlation of an indicator - with the general antioxidant ability of blood (OAS) and superoxide dismutase (SOD). The HOMA-IR index has direct correlation link of moderate force with levels of a leptin of blood, LDL-ok, OOS, pro-inflammatory tsitokin, negative correlation of moderate force - with OAS, SOD. At patients with psoriasis with MS direct strong correlation link of level of a leptin of blood with activity of the studied pro-inflammatory cytokine, LDL-ok, OOS moderated is established with the level of insulin in the blood., the HOMA-IR index, strong negative correlation with OAS, SOD. Conclusion. Presence at patients with psoriasis of signs of a metabolic syndrome is followed by increase in activity of immune and inflammatory mechanisms, development of oxidative stress.

A differentiated approach to the dental caries prevention in children with different levels of caries risk

2020 ◽  
Vol 20 (3) ◽  
pp. 211-215
Author(s):  
T. N. Tserakhava ◽  
N. V. Shakavets ◽  
E. I. Melnikava ◽  
M. I. Klenovskaya ◽  
D. N. Naumovich ◽  
...  
Keyword(s):  
Oral Hygiene ◽  
Calcium Phosphates ◽  
Clinical Effectiveness ◽  
Control Group ◽  
Caries Risk ◽  
Health Group ◽  
High Caries Risk ◽  
Permanent Molars ◽  
Different Levels ◽  
First Permanent Molars

Relevance. Prevention of caries of the first permanent molars is one of the most relevant problems in pediatricdentistry.Purpose – to develop an algorithm for prevention of first permanent molars caries in children with differentlevels of caries risk.Materials and methods. The article presents the results of the implementation of the algorithm for prevention of first permanent molars caries in children with different levels of caries risk. This algorithm includes a comprehensive assessment of the values of indices dmft, DMFT, OHI-S, and the patient's health group is also taken into account. The study involved 253 children aged 6-7 years divided into 4 groups: 3 groups of children depending on the health group and the control group. 3 subgroups were identified in each group – with a low, medium, and high caries risk. We developed preventive measures schemes were for children of each group including training in oral hygiene; controlled and home toothbrushing using fluoride-containing toothpastes; applications of varnishes containing fluoride, calcium, phosphates from 2 to 3 times a year; fissure sealing of the first permanent molars. We carried out these activities were for 24 months, and then evaluated theirs effectiveness. Children in the control group were trained in oral hygiene. The clinical effectiveness of medical prophylaxis was evaluated by changes in the above clinical indicators.Results. In group of children with medium caries risk the increase in caries was 0.09, and the reduction in caries was 89.65%. In children with a low and high caries risk no increase in caries was observed; the reduction in the intensity of caries was 100%. A significant decrease in OHI-S oral hygiene index values was noted in all groups (p < 0.05). We noted high preventive efficacy of fissures sealing in the first permanent molars. No occlusal surface caries developed in sealed fissures.Conclusions. The application of the proposed preventive schemes in patients demonstrates high efficacy of fluoride and calcium-containing varnishes and sealing the fissures of the first permanent molars. 

scholarly journals Equity considerations in outcome measures of the HIV pre-exposure prophylaxis care continuum in high-income countries: a systematic review protocol

BMJ Open ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. e040701
Author(s):  
Melissa Cabecinha ◽  
Danielle Solomon ◽  
Greta Rait ◽  
John Saunders ◽  
Hamish Mohammed ◽  
...  
Keyword(s):  
Systematic Review ◽  
English Language ◽  
Outcome Measure ◽  
Assessment Tool ◽  
Public Health Practice ◽  
Risk Groups ◽  
Care Continuum ◽  
Quantitative Studies ◽  
Prep Implementation ◽  
Exposure Prophylaxis

IntroductionHIV pre-exposure prophylaxis (PrEP) is an effective intervention to reduce acquisition of HIV. PrEP provision has increased in recent years, however, it is not known whether PrEP implementation has been equitably implemented across all risk groups, particularly groups experiencing high levels of health inequity. A PrEP care continuum (PCC) has been proposed to evaluate the success of PrEP implementation programmes, but the extent to which health equity characteristics are currently taken into account in the PCC has not been described. The objectives of this proposed systematic review are to (i) identify and collate outcome measure definitions for the main stages of the PCC (awareness, acceptability, uptake, adherence and retention), (ii) describe how equity characteristics are considered in outcome definitions of the PCC and (iii) describe data sources for capturing equity characteristics.Methods and analysisQuantitative studies published between 1 January 2012 and 3 March 2020 will be included. Five databases (MEDLINE, PubMed, Embase, Cumulative Index to Nursing and Allied Health Literature, Applied Social Sciences Index and Abstracts) will be searched to identify English language publications that include an outcome measure definition of at least one of the five main stages of the PCC. Risk of bias will be assessed using the Effective Public Health Practice Project Quality Assessment Tool for Quantitative Studies. Data on outcome measure definitions and equity characteristics will be extracted. Results will be presented in a narrative synthesis and all findings will be reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.Ethics and disseminationEthical approval is not required. The results will be disseminated via submission for publication to a peer-reviewed journal when complete. The review findings will have relevance to healthcare professionals, policymakers and commissioners in informing how to best evaluate PrEP implementation programmes and inform new implementation strategies for vulnerable and less advantaged populations.PROSPERO registration numberCRD42020169779.

Validation of different Cariogram settings and factor combinations in preschool children from areas with high caries risk

2019 ◽  
Vol 29 (4) ◽  
pp. 448-455 ◽  
Author(s):  
Eleftheria Birpou ◽  
Andreas Agouropoulos ◽  
Svante Twetman ◽  
Katerina Kavvadia
Keyword(s):  
Preschool Children ◽  
Caries Risk ◽  
High Caries Risk

Growth and Development of the Wheat Tiller. II. The Dynamics of Tiller Growth

1975 ◽  
Vol 23 (5) ◽  
pp. 745 ◽  
Author(s):  
RF Williams ◽  
RHM Langer
Keyword(s):  
Negative Correlation ◽  
Growth And Development ◽  
Critical Event ◽  
Vascular Differentiation ◽  
Strong Negative Correlation ◽  
Physical Constraints ◽  
Size Dependent ◽  
Bud Growth ◽  
Time Relation ◽  
Tiller Bud

From an analysis of the length-time relation for tiller growth in wheat it was concluded that tillers which emerged traced a discontinuous curve, and that the discontinuity marked a critical event in tiller growth. Tiller buds which did not emerge as tillers continued to grow even more slowly, at least until anthesis of the primary shoot. The critical event was identified as that of escape from the cavity in which the bud was tightly contained throughout early development. The timing of vascular differentiation in tiller buds was shown to be size-dependent and there was no evidence for any correlation with the critical event of escape. A strong negative correlation between the lengths of the 3rd tiller buds and their subtending internodes was established, and the presence or absence of the 4th tiller bud was also correlated with its internode length. Current hypotheses relating to apical dominance are reviewed, and it is suggested that the dynamic physical constraints implicit in tiller bud growth add a further complication. It was concluded that hormonal, nutritional and constraint mechanisms need to be integrated as partial mechanisms which interacted at the interfaces between successive levels within apical systems.

Sign in / Sign up

Export Citation Format

Share Document