Therapeutic Effect of Abelmoschus manihot on Type 2 Diabetic Nonproliferative Retinopathy and the Involvement of VEGF

Objective. To evaluate the efficacy of Abelmoschus manihot in treating type 2 diabetic nonproliferative retinopathy. Methods. It was a randomized controlled clinical trial. The recruited eighty subjects with type 2 diabetic nonproliferative retinopathy were randomly divided into treatment group and control group. The two groups received basic treatments including control of blood glucose, blood pressure and blood lipid, management of diet, exercise and health education, and monitoring of relevant indicators. Additionally, the treatment group was given oral administration of Abelmoschus manihot. All subjects were followed up on monthly basis for consecutive six months. The related parameters including diabetic retinopathy (DR) incidence rates, “Early Treatment Diabetic Retinopathy Study” (ETDRS) vision scores, retinal thicknesses in macular region, serum vascular endothelial growth factor (VEGF) levels, and biochemical indicators of both groups before and after treatment were accurately collected and statistically analyzed. Results. There were no significant differences of DR severity levels, ETDRS vision scores, macular retinal thicknesses such as cube average thickness (CAT), central subfield thickness (CST), and cube volume (CV), and serum VEGF levels between two groups before treatment. Meanwhile, there were no significant differences of demographic characteristics, case terminations, blood glucose, blood lipid, blood pressure, biochemical indicators of hepatorenal function, hypoglycemic drugs, hypotensive drugs, and other basic treatments between two groups during six months treatment. The present study suggested that the remission rate of DR and the ETDRS vision score in the treatment group were significantly higher than those of the control group (remission rate: 25.4% vs 9.3%, P=0.01; ETDRS score: 78 (72, 82) vs 72 (67, 80), P=0.0002) while the progression rate of DR in the treatment group was significantly lower than that of the control group (progression rate: 4.2% vs 18.7%, P=0.007) after six months treatment. In addition, the CAT, CST, CV, and serum VEGF levels of the treatment group were significantly improved after the treatment (CAT: 286 (278, 302) vs 282 (270, 295) μm, P<0.0001; CST: 251 (239, 274) vs 248 (235, 265) μm, P<0.0001; CV: 10.3 (10.0, 10.9) vs 10.1 (9.7, 10.6) mm3, P<0.0001; VEGF: 0.21 (0.14, 0.58) vs 0.16 (0.10, 0.23) ng/ml, P=0.0026), while there were no significant differences of the control group before and after treatment (CAT: 287 (279, 294) vs 287 (279, 295) μm, P=0.27; CST: 250 (240, 266) vs 252 (238, 266) μm, P=0.72; CV: 10.4 (10.1, 10.6) vs 10.4 (10.1, 10.7) mm3, P=0.53; VEGF: 0.21 (0.13, 0.66) vs 0.23 (0.12, 0.64) ng/ml, P=0.85). Conclusion. The study offered the novel evidence for the therapeutic effect of Abelmoschus manihot on type 2 diabetic nonproliferative retinopathy, which was associated with improved VEGF. This trial is registered with ChiCTR1800019292.

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PERBEDAAN PENURUNAN TEKANAN DARAH PRA LANSIA PRE HIPERTENSI YANG DIBERI JUS TOMAT (Lycopersicum grandifilum)

JURNAL MEDIA KESEHATAN ◽

10.33088/jmk.v10i2.337 ◽

2018 ◽

Vol 10 (2) ◽

pp. 152-158

Author(s):

Hari Yani Fadillah

Keyword(s):

Blood Pressure ◽

Treatment Group ◽

Block Design ◽

Pressure Control ◽

Tomato Juice ◽

Control Group ◽

Randomized Block Design ◽

Before And After ◽

Blood Pressure Treatment ◽

And Control

The research aims to know the effect of tomato juice on blood pressure in pre-elderly pre hypertension at Posbindu Puskesmas Nusa Indah Bengkulu City.The design of research was a quasi experiment include pre test post test. This population was all patients posbindu aged 45-59 years. Sampling of this research randomized block design of one factorial were 6 samples divided into treatment and control group. The data which have been analyzed using univariate and bivariate. From this research were obtained the results such as the mean of sistole blood pressure before and after intervention in treatment group p = 0,273 and diastole p = 0,27. Mean systole blood pressure control group p = 0.060 and diastole p = 2.14. Distribution of tomato juice (Lycopersicum grandifilum) did not given affect the decrease in blood pressure of systole diastole before and after intervention in pre-elderly pre hypertension. Whereas the difference in mean systole of blood pressure treatment and control group p = 0.935 and diastolic of blood pressure p = 0.678. There ware not difference in mean of blood pressure in the tomato juice treatment group and control of Vitamin C. The result concluded there were not effect of tomato juice (Lycopersicum grandifilum) on systolic of blood pressure in pre-elderly pre hypertension at Posbindu Puskesmas Nusa Indah Bengkulu City.

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Medium- and Short-Term Interventions with Ma-Pi 2 Macrobiotic Diet in Type 2 Diabetic Adults of Bauta, Havana

Journal of Nutrition and Metabolism ◽

10.1155/2012/856342 ◽

2012 ◽

Vol 2012 ◽

pp. 1-10 ◽

Cited By ~ 4

Author(s):

Carmen Porrata-Maury ◽

Manuel Hernández-Triana ◽

Eduardo Rodríguez-Sotero ◽

Raúl Vilá-Dacosta-Calheiros ◽

Héctor Hernández-Hernández ◽

...

Keyword(s):

Blood Pressure ◽

Dietary Intervention ◽

Diabetic Patients ◽

Short Term ◽

Type 2 Diabetic Patients ◽

Biochemical Indicators ◽

Serum Biochemical ◽

Macrobiotic Diet ◽

Type 2 Diabetic

Background.In Cuba, the Ma-Pi 2 macrobiotic diet has shown positive results in 6-month assays with type 2 diabetic patients. The objective of this study was to assess the influence of this diet at short and medium terms.Methods.Sixty-five type 2 diabetic volunteers were included for dietary intervention, institutionally based for 21 days and followed later at home, until completing 3 months. 54 of them stayed until assay end. Before intervention, and after both assay periods, they were submitted to anthropometric records, body composition analyses and measurements of serum biochemical indicators, glycemic profile in capillary blood, blood pressure, and medication consumption; food intake was evaluated by the 3-day dietary recall.Results.During the intervention, the energy intake was 200 kcal higher at instance of more complex carbohydrates and dietary fiber and despite less fat and protein. Blood pressure and serum biochemical indicators decreased significantly in both periods; the safety nutritional indicators (hemoglobin, serum total proteins, and albumin) showed no variations. The global cardiovascular risk decreased and insulin consumption dropped by 46% and 64%, in both periods, respectively.Conclusions.The Ma-Pi 2 macrobiotic diet was a successful therapy at short term and after 3-month home-based intervention, for type 2 diabetics.

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The Role of Liuwei Dihuang Pills and Ginkgo Leaf Tablets in Treating Diabetic Complications

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2016/7931314 ◽

2016 ◽

Vol 2016 ◽

pp. 1-8 ◽

Cited By ~ 7

Author(s):

Yue Zhao ◽

Jiangyi Yu ◽

Jingshun Liu ◽

Xiaofei An

Keyword(s):

Blood Pressure ◽

Treatment Group ◽

Microvascular Complications ◽

Vascular Complications ◽

Control Group ◽

Controlled Clinical Trial ◽

Cerebrovascular Events ◽

Liuwei Dihuang Pills ◽

Ginkgo Leaf

Objective. To observe the clinical prophylactic and therapeutic efficacy of Liuwei Dihuang Pills and Ginkgo Leaf Tablets for type 2 diabetic vascular complications. Methods. It was a randomized, double-blind and placebo-controlled clinical trial. 140 outpatients with type 2 diabetes were recruited and randomly divided into the treatment group and control group. The two groups were given basic therapy (management of blood sugar, blood pressure, etc.). Additionally, the treatment group was given Liuwei Dihuang Pills and Ginkgo Leaf Tablets, while the control group was given Liuwei Dihuang Pills and Ginkgo Leaf Tablets placebos. All subjects were followed up for consecutive 36 months and observed monthly. The clinical data as urinary microalbumin to urinary creatinine ratio (Umalb/cr), carotid intima-media thickness (IMT), diabetic nephropathy (DN) and diabetic retinopathy (DR) prevalence, cardiovascular and cerebrovascular events, blood glucose, and blood pressure were collected and analyzed statistically. Results. After 36-month treatment, the Umalb/cr level and DN and DR prevalence in treatment group were all significantly lower than control group (P<0.05). However, the IMT level and the incidence of cardiovascular and cerebrovascular events were not significantly different between the two groups (P>0.05). Conclusions. Liuwei Dihuang Pills and Ginkgo Leaf Tablets are beneficial to diabetic microvascular complications, while the efficacy to diabetic macrovascular complications needs more observations.

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What is Important For You (WIFY) dan Life Map berbasis Goal Attaintment Model terhadap Self Care Behaviour pada Pasien Diabetes Melitus Tipe 2

Journal of Health Sciences ◽

10.33086/jhs.v12i1.793 ◽

2019 ◽

Vol 12 (1) ◽

pp. 1-11

Author(s):

Kusnanto Kusnanto ◽

Moh Zen Arifin ◽

Ira Suarilah ◽

Hidayat Arifin

Keyword(s):

Goal Attainment ◽

Self Care ◽

Control Group ◽

P Value ◽

Significant Difference ◽

Before And After ◽

And Control ◽

Type 2 Diabetic ◽

Care Behavior

Introduction: Diabetes mellitus was an uncurable metabolic disease but it can be controlled. Diabetes can be controlled independently by diabetic with diabetes self-care behavior. Self-care behavior was challenge problem causing in adherence in majority diabetic clients especially in Persadia Darmo Hospital. Method: Research design was Quasy-Experiment study among type 2 diabetic client. This study involved 30 samples taken by purposive sampling. The independent variable were What is Important For You (WIFY) and Life Map. The dependent variable was self-care behavior. Data were taken by using SDSCA questionnaire then analyzed by using t-test with a= £0.05. Result and Analyze: WIFY and Life Map change self-care behavior in treatment group before and after treatment significantly with p value = 0,024. There was significant difference between treatment and control group of self-care behavior with p value = 0,029. Discussion: It could be concluded that application of WIFY and Life Map with goal attainment model increase self-care behavior in type 2 diabetic clients. The use of this approach could be optimizing diabetic counseling and education for clients. Further research to investigate WIFY and Life map effect on blood glucose level and HbA1c test in Type 2 Diabetic.

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Endothelin Level and Its Correlation with Uric Acid in Type 2 Diabetic Multiuse Patients

Al-Mustansiriyah Journal of Science ◽

10.23851/mjs.v31i3.849 ◽

2020 ◽

Vol 31 (3) ◽

pp. 35

Author(s):

Zahraa Majid Ismail ◽

Zyad Hussein Jawad ◽

Ali Jasim Hammood

Keyword(s):

Blood Pressure ◽

Uric Acid ◽

Significant Positive Correlation ◽

Endothelial Damage ◽

Control Group ◽

Factors Influencing ◽

Direct Linkage ◽

The Mean ◽

Type 2 Diabetic

This research aims to find the direct linkage among the Uric acid rates with Endothelin (ET-1), which is considered the indication of endothelial dysfunction or endothelial damage in patients with T2-DM. This study, included 96 patients with T2-DM and 96 controls, the mean age ranged (56.73 ± 9.14), (56.42 ± 8.74) respectively. Results showed a highly significant increase in Endothelin (ET-1) levels, uric acid, urea, and systolic blood pressure (SBP) was observed as compared with the control group, while Diastolic blood pressure (DBP) and body mass (BMI) were not substantially increased. Additionally, a significant positive correlation was found between ET-1 with uric acid, urea, SBP, DBP in patients with T2-DM (p < 0.05). Finally, elevated uric acid levels in older people who have chronic blood pressure are one of the factors influencing the increased release of ET-1, thus the development of cardiovascular disease.

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PELAYANAN HOME CARE TERHADAP TINGKAT KEMANDIRIAN KELUARGA DALAM MERAWAT ANGGOTA KELUARGA DENGAN DIABETES MELITUS TIPE 2

Jurnal Persatuan Perawat Nasional Indonesia (JPPNI) ◽

10.32419/jppni.v1i1.10 ◽

2017 ◽

Vol 1 (1) ◽

pp. 9

Author(s):

Lia Meilianingsih ◽

Ridwan Setiawan

Keyword(s):

Treatment Group ◽

Home Care ◽

Family Members ◽

Home Care Services ◽

Control Group ◽

Care Services ◽

The Family ◽

Before And After ◽

Taking Care

ABSTRAKTujuan penelitian: Penelitian ini bertujuan untuk mengetahui pengaruh pelayanan home careterhadap tingkat kemandirian keluarga dalam merawat anggota keluarga dengan diabetesmelitus (DM) tipe 2 di Wilayah Kerja Puskesmas Pasirkaliki, Bandung. Metode: Desain penelitianmenggunakan quasi experiment dengan pendekatan pre- post-test control group design. Sampelberjumlah 27 orang untuk kelompok perlakuan dan 27 orang untuk kelompok kontrol. Teknikpengambilan sampel secara purposive sampling. Intervensi pelayanan home care dilakukan enamkali kunjungan. Kemandirian keluarga dalam merawat anggota keluarga dengan DM tipe 2 sebelumdan sesudah diberikan pelayanan home care dilakukan dengan uji statistik T test independent dandependent. Instrumen untuk menilai kemandirian keluarga dengan kuesioner tentang kemandiriankeluarga dari Kementrian Kesehatan. Hasil: Terdapat perbedaan yang bermakna pada tingkatkemandirian keluarga dalam merawat anggota keluarga dengan DM tipe 2 sebelum dan setelahdilakukan pelayanan home care pada kelompok perlakuan (p=0,00), selanjutnya terdapat perbedaanyang bermakna juga antara kelompok kontrol dan kelompok perlakuan (p=0,00). Diskusi: Untukmencapai hasil yang maksimal perlu peningkatan pelayanan keperawatan keluarga dalam bentukHome Care secara berkesinambungan sehingga kemandirian keluarga dalam mengenal danmengatasi masalah kesehatan di keluarganya semakin meningkat. Simpulan: pelayanan homecare dapat meningkatkan kemandirian keluarga dalam merawat anggota keluarga dengan DM tipe2.Kata Kunci: diabetes melitus tipe 2, home care, kemandirian keluargaABSTRACTObjectives: This study aimed to identify the effect of home care services on the levels of independenceof family in taking care of family members with type 2 diabetes mellitus (DM) at Pasirkaliki PublicHealth Centre, Bandung. Method: This study was quasi-experimental with pre-post-test approachcontrol group design. Samples were divided into treatment group and control group, each of whichconsisted of 27 people. They were taken using purposive sampling. Home care services interventioninvolved six visits. The independence of the family in taking care of family members with type 2DM before and after home care services was analyzed using independent and dependent t test.Result: There were signifi cant differences in the levels of independence of the family in taking careof family members with type 2 DM before and after the home care services in the treatment group(p=0.00). There were also signifi cant differences between the control group and the treatment group(p 0.00). Discussion: In order to achieve maximum results, it was necessary to improve familynursing services in the form of Home Care on an ongoing basis so that the independence of thefamily in identifying and addressing family health issues would increase. Conclusion: Home careservices could improve the independence of the family in taking care of family members with type 2DM.Keywords: type 2 diabetes mellitus, home care, independence of family.

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Short-term renoprotective effect of SGLT-2 inhibitor for renal function and albuminuria in type 2 diabetes

10.21203/rs.3.rs-23179/v1 ◽

2020 ◽

Author(s):

Mitsunobu Kubota ◽

Eri SHiroyama ◽

Kanako Tanaka ◽

Yoko Yoshii

Keyword(s):

Blood Pressure ◽

Body Weight ◽

Diabetic Patients ◽

Protective Effects ◽

Renal Protection ◽

Short Term ◽

Type 2 Diabetic Patients ◽

Before And After ◽

Type 2 Diabetic

Abstract Background Progression of diabetic nephropathy in type 2 diabetic patients is a factor that determines the prognosis of life. Empagliflozin and canagliflozin, two oral diabetic SGLT-2 inhibitors, have shown improved renal outcomes in type 2 diabetic patients with chronic kidney disease in a large clinical study. These results suggest that SGLT-2 inhibitors could be used not only for hypoglycemic effects, but also for renal protective effects in patients with type 2 diabetes. It is not fully understood in which contexts the use of SGLT-2 inhibitors is likely to exert its renal protective effects. The purpose of this study was to clarify the profiles of patients in whom SGLT-2 inhibitors are more likely to exert a renal protective effect in clinical practice. We examined renal function and urinary albumin changes in short-term use of SGLT-2 inhibitors by patient background. Methods We retrospectively analyzed the chart information of sixty-three type 2 diabetic patients (33 males, 30 females, average age 53.0 ± 13.0 years) who were given usual doses of a SGLT-2 inhibitor. We investigated changes in body weight, blood pressure, glucose metabolism index, lipid metabolism index, estimated glomerular filtration rate (eGFR) and albuminuria (urinary albumin-to-creatinine ratio, UACR) three months before and after administration of a SGLT-2 inhibitor. Results Three months after administration of an SGLT-2 inhibitor, there were improvements in glucose tolerance, weight loss, blood pressure, and lipid indices. In all cases, there was no significant change in eGFR, but UACR decreased significantly. UACR decreased regardless of Angiotensin II Receptor Blocker medication and significantly decreased in the nephropathy stage 2 and 3 groups. UACR decreased only in the group in which blood pressure, body weight, and HbA1c decreased before and after administration of the SGLT-2 inhibitor. Conclusions Our study shows that SGLT-2 inhibitors are independent of renin-angiotensin system (RAS) inhibitors, and in addition to direct renal protection, the comprehensive effects of SGLT-2 inhibitors, which lower body weight, blood pressure, and blood glucose, are also important for their renal protection effects.

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Short-term renoprotective effect of SGLT-2 inhibitor for renal function and albuminuria in type 2 diabetes: a retrospective study

10.21203/rs.3.rs-35892/v1 ◽

2020 ◽

Author(s):

Mitsunobu Kubota ◽

Eri Shiroyama ◽

Kanako Tanaka ◽

Yoko Yoshii

Keyword(s):

Blood Pressure ◽

Body Weight ◽

Diabetic Patients ◽

Protective Effects ◽

Renal Protection ◽

Short Term ◽

Type 2 Diabetic Patients ◽

Before And After ◽

Type 2 Diabetic

Abstract Background Progression of diabetic nephropathy in type 2 diabetic patients is a factor that determines the prognosis of life. Empagliflozin and canagliflozin, two oral diabetic SGLT-2 inhibitors, have shown improved renal outcomes in type 2 diabetic patients with chronic kidney disease in a large clinical study. These results suggest that SGLT-2 inhibitors could be used not only for hypoglycemic effects, but also for renal protective effects in patients with type 2 diabetes. It is not fully understood in which contexts the use of SGLT-2 inhibitors is likely to exert its renal protective effects. The purpose of this study was to clarify the profiles of patients in whom SGLT-2 inhibitors are more likely to exert a renal protective effect in clinical practice. We examined renal function and urinary albumin changes in short-term use of SGLT-2 inhibitors by patient background. Methods We retrospectively analyzed the medical record information of sixty-three type 2 diabetic patients (33 males, 30 females, average age 53.0 ± 13.0 years) who were given usual doses of a SGLT-2 inhibitor. We investigated changes in body weight, blood pressure, glucose metabolism index, lipid metabolism index, estimated glomerular filtration rate (eGFR) and albuminuria (urinary albumin-to-creatinine ratio, UACR) three months before and after administration of a SGLT-2 inhibitor. Results Three months after administration of an SGLT-2 inhibitor, there were improvements in glucose tolerance, weight loss, blood pressure, and lipid indices. In all cases, there was no significant change in eGFR, but UACR decreased significantly. UACR decreased regardless of Angiotensin II Receptor Blocker medication and significantly decreased in nephropathy patients with microalbuminuria or overt albuminuria. UACR decreased only in the group in which blood pressure, body weight, and hemoglobin A1c decreased before and after administration of the SGLT-2 inhibitor. Conclusions Our study shows that the renoprotective effects of SGLT-2 inhibitors are more likely to be exerted in diabetic nephropathy patients who have advanced to at least microalbuminuria stage, and in addition to direct renal protection, the comprehensive effects of SGLT-2 inhibitors, which lower body weight, blood pressure, and blood glucose, are also important for their renal protection effects.

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LITERATUR REVIEW : EFEKTIVITAS BUAH MENGKUDU (Morinda Citrifolia L.) TERHADAP PENURUNAN HIPERTENSI

Jurnal Kebidanan ◽

10.35872/jurkeb.v13i02.460 ◽

2021 ◽

Vol 13 (02) ◽

pp. 128

Author(s):

Roikatul Miskiyah ◽

Friska Realita

Keyword(s):

Blood Pressure ◽

Treatment Group ◽

Systolic Blood Pressure ◽

Statistical Test ◽

Morinda Citrifolia ◽

Control Group ◽

P Value ◽

Fruit Extract ◽

Before And After ◽

Interaction Factors

ABSTRAKLatar Belakang : Hipertensi adalah The Silent Disease sehingga seseorang tidak akan mengetahui jika dirinya menderita hipertensi atau tekanan darah tinggi. Meningkatnya tekanan darah sistolik lebih besar dari 120 mmHg dan diastolik lebih besar dari 80 mmHg pada dua kali pengukuran dengan selang waktu 5 menit dalam keadaan cukup istirahat disebut dengan Hipertensi, Hal tersebut timbul karena adanya banyak faktor interaksi resiko yang dimiliki seseorang. Tujuan : Penelitian ini bertujuan untuk menganalisis efektivitas buah mengkudu dalam menurunkan hipertensi. Metode : Pencarian artikel nasional ini dilakukan dengan basis data seperti google scohlar. Dengan kata kunci: “hipertensi”.”ekstrak buah mengkudu”. Dan penulis menemukan 7 artikel yang relevan 2014-2018. masing-masing mewakili efektivitas buah mengkudu terhadap penurunan hipertensi terhadap semua sampel. Hasil : Tujuh artikel yang di dapat, Menunjukkan hasil uji statistik p Value 0,015 (p<0,05). berarti ada pengaruh antara tekanan darah siastolik maupun diastolik penderita hipertensi sebelum dan sesudah diberikan air perasan buah mengkudu. Kesimpulan : tekanan darah pada kelompok perlakuan sesudah intervensi buah mengkudu mengalami penurunan tekanan darah dibandingkan dengan kelompok control, efektivitas buah mengkudu ialah salah satu pengobatan non farmakologis.Kata kunci: Hipertensi, Ekstrak Buah MengkuduTHE EFFECTIVENESS OF NONI FRUIT (MORINDA CITRIFOLIA L.) TO REDUCE HYPERTENSIONABSTRACTBackground : Hypertension is The Silent Disease so that a person will not know if he has hypertension or high blood pressure. Increased systolic blood pressure greater than 120 mmHg and diastolic greater than 80 mmHg in two measurements with an interval of 5 minutes in a state of sufficient rest is called Hypertension. This arises because there are many risk interaction factors that a person has. Objective : This study aims to analyze the effectiveness of noni fruit in reducing hypertension. Methods : This national article search was carried out using databases such as Google Scohlar. With keywords: "hypertension", "noni fruit extract". And the author found 7 relevant articles 2014-2018. each represents the effectiveness of noni fruit in reducing hypertension in all samples. Results : Seven articles were obtained, showing the results of the statistical test p Value of 0.015 (p <0.05). This means that there is an influence between systolic and diastolic blood pressure in patients with hypertension before and after being given noni juice. Conclusion : blood pressure in the treatment group after the noni fruit intervention decreased blood pressure compared to the control group, the effectiveness of noni fruit is one of the non-pharmacological treatments.Keywords: Hypertension, Mengkudu Fruit Extract.

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EFFECTS OF ISOLATED AND COMBINED EFFECTS OF AEROBIC DANCING AND RESISTANCE TRAINING ON SYSTOLIC BLOOD PRESSURE OF TYPE-2 DIABETIC PATIENTS

International Journal of Research -GRANTHAALAYAH ◽

10.29121/granthaalayah.v5.i10.2017.2261 ◽

2017 ◽

Vol 5 (10) ◽

pp. 11-16

Author(s):

D. Maniazhagu

Keyword(s):

Blood Pressure ◽

Resistance Training ◽

Systolic Blood Pressure ◽

Control Group ◽

Diabetic Patients ◽

Combined Effects ◽

Type 2 Diabetic Patients ◽

Experimental Group ◽

Type 2 Diabetic

The purpose of study was to find out the effects of isolated and combined effects of aerobic dancing and resistance training on systolic blood pressure of type-2 diabetic patients. To achieve the purpose of the study, 60 type 2 diabetic patients from Karaikudi town, Sivaganga District, Tamilnadu were selected as subject at random. The study was formulated as pre and posttest random group design, in which sixty subject were divided into four equal groups. The experimental group-1 (n=15, AD, experimental group-2 (n=15, RT), experimental group – 3 (n=15, COM-T) and group-4 (n=15, CG) served as a control group. In this study, three training programme were adopted as independent variable, i.e., aerobic dancing, resistance training and combined training. The systolic blood pressure was chosen as dependent variable. The collected pre and post data was critically analyzed with apt statistical tool of analysis of co-variance. The Scheffe’s post hoc test was used to find out pair-wise comparisons between groups. The results of the present study proved that the three training interventions have produced significantly altered on systolic blood pressure.

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