scholarly journals Adherence to Isoniazid Preventive Therapy among Under-Five Children in Contact with Adult Bacteriologically Confirmed Pulmonary Tuberculosis Patients: A Mixed-Method Study

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Getachew Seid ◽  
Tsegaye Tsedalu ◽  
Marta Ayele ◽  
Faham Khamesipour
Keyword(s):  
Pulmonary Tuberculosis ◽  
World Health Organization ◽  
Study Design ◽  
Addis Ababa ◽  
Preventive Treatment ◽  
Preventive Therapy ◽  
World Health ◽  
Tuberculosis Patients ◽  
The World ◽  
Health Organization

Background. The World Health Organization recommends that all children below the age of five who have household contact with an infectious tuberculosis case should receive isoniazid preventive treatment for at least six months after the active tuberculosis disease has been ruled out. This research aims to determine the adherence of children, eligible for isoniazid preventive treatment, to the treatment who had contact with pulmonary tuberculosis patients. Methods. A mixed study design was used to prospectively assess the adherence to IPT among children under the age of 5 in contact with pulmonary TB patients through the quantitative study design and barriers of adherence in view of health care professionals and the family of children through a descriptive qualitative study. The study was conducted from July 2019 to December 2019 in Addis Ababa. Data were collected by a structured datasheet from the selected health center registration book. Data were entered into Epi Data software and analyzed by using SPSS version 20. Descriptive statistical methods were used to summarize the sociodemographic characteristics of the study participants. Result. The ratio of the total number of pulmonary tuberculosis index cases recruited into the study to the number of child contacts aged less than 5 years was 1 : 1.32. The total isoniazid preventive treatment uptake in this study was 75.2%; one-fifth (21.3%) of the children who started IPT did not complete the full course of six-month isoniazid preventive treatment. Except for HIV not to be tested ( P < 0.001 ), there was no significant association of the listed risk factors in default to complete the full six months of preventive treatment. Conclusion. Enrolment of eligible children for isoniazid preventive treatment in the urban city Addis Ababa was still below the target of the World Health Organization End tuberculosis strategy by 2030. The treatment adherence rate also needs a great deal of effort to achieve the strategy. Child default after the first visit indicates a lack of understanding about the benefit and safety of preventive therapy in young children among families of TB patients, and awareness-creating efforts by health extension workers will help to improve the outcomes.

scholarly journals Magnitude of infertility and associated factors among women attending selected public hospitals in Addis Ababa, Ethiopia: a cross-sectional study

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Mekdes Akalewold ◽  
Getachew W. Yohannes ◽  
Ziyad Ahmed Abdo ◽  
Yonas Hailu ◽  
Aynye Negesse
Keyword(s):  
World Health Organization ◽  
Addis Ababa ◽  
Cross Sectional Study ◽  
Public Hospitals ◽  
World Health ◽  
Care Providers ◽  
Sectional Study ◽  
Cross Sectional ◽  
The World ◽  
Health Organization

Abstract Introduction The World Health Organization estimated that approximately 48 million couples and 186 million people are infertile worldwide. Although the problem of infertility is increasing worldwide, as well as in Ethiopia, there are limited studies done. Therefore, this study aims to determine the magnitude of infertility and the major risk factors in three governmental hospitals in Addis Ababa, Ethiopia. Method An institutional-based cross-sectional study design was used to conduct the study. The participants were selected by using a systematic random sampling technique. Data were collected through an interview using a structured questionnaire. The data were entered into Epi Data version 3.1 and exported to SPSS version 25 for analysis. Logistic regression was used to identify the predictor variables. Statistical significance was considered at a P < 0.05 with an adjusted odds ratio calculated at 95% CI. Result The overall prevalence of infertility was 27.6% (95%CI = 23.2, 32.0). Of these, 14.4% had primary infertility, and 13.2% had secondary infertility. Those whose duration of marriage was less than 60 months [AOR = 3.85; 95%CI 1.39, 10.64], had a history of fallopian tube obstructions [AOR = 8.27; 95%CI 2.36, 28.91], had irregular frequency of coitus [AOR = 37.4; 95%CI 11.29, 124.114], had more than one sex partner [AOR = 3.51; 95%CI 1.64, 7.54], had an abortion greater than 3 times [AOR = 6.89; 95%CI 1.28, 37.09], and had partners who currently consumed alcohol [AOR = 1.31; 95%CI 1.11, 1.86] were more likely to be infertile than their counterparts. Conclusion According to the results of this study, the prevalence of infertility was high compared to the global estimate of the World Health Organization. The government, health care providers, and researchers should emphasize developing appropriate strategies, research, education, and awareness creation of infertility and its potential causes.

scholarly journals GAMBARAN PENGETAHUAN PASIEN TUBERCULOSIS PARU TENTANG PUTUS OAT (OBAT ANTI TUBERCULOSIS) DI RSU IPI MEDAN TAHUN 2019

2021 ◽  
Vol 7 (1) ◽  
pp. 78-83
Author(s):  
Jenti Sitorus
Keyword(s):  
Pulmonary Tuberculosis ◽  
Sampling Technique ◽  
Medical Personnel ◽  
World Health ◽  
Primary Data ◽  
Accurate Information ◽  
Tuberculosis Patients ◽  
The World ◽  
Health Organization ◽  
India And China

Pulmonary tuberculosis is an infectious disease that attacks the lungs which is typically characterized by the formation of granulomas causing tissue neocrosis. Pulmonary tuberculosis is caused by "mycrobacterium tuberculosis" a type of rod-shaped germ with a length of 1-4 / mm and a thickness of 0.3 -0.6 / mm. The World Health Organization (WHO) in 2007 stated that the number of tuberculosis sufferers in Indonesia was around 528 thousand or in third place in the world after India and China. The WHO report in 2009 recorded Indonesia's ranking according to fifth position with the number of tuberculosis sufferers of 429 thousand people, namely India, China, South Africa, Nigeria, and Indonesia (source WHO Global Tuberculosis Control 2010). This study aims to describe the knowledge of pulmonary tuberculosis patients about anti-tuberculosis drug withdrawal at RSU IPI Medan who is experiencing pulmonary tuberculosis. The sampling technique used in this research is Probability Sampling with the Random Sampling technique. Then the number of samples is 40 respondents. researchers used primary data. With the results of the study, it is hoped that respondents will increase their knowledge by finding out and caring about the health of others in order to prevent the transmission of pulmonary tuberculosis and change bad behavior for the better, with the participation and cooperation of medical personnel and other health teams in provide precise and accurate information.

scholarly journals Guidance for the Evaluation of Tuberculosis Diagnostics That Meet the World Health Organization (WHO) Target Product Profiles: An Introduction to WHO Process and Study Design Principles

2019 ◽  
Vol 220 (Supplement_3) ◽  
pp. S91-S98 ◽  
Author(s):  
Claudia M Denkinger ◽  
Samuel G Schumacher ◽  
Christopher Gilpin ◽  
Alexei Korobitsyn ◽  
William A Wells ◽  
...  
Keyword(s):  
World Health Organization ◽  
Study Design ◽  
Review Process ◽  
World Health ◽  
Index Test ◽  
Target Product ◽  
Incidence And Mortality ◽  
The World ◽  
Health Organization ◽  
Evidence Generation

Abstract Existing high-priority target product profiles (TPPs) of the World Health Organization (WHO) establish important needs for tuberculosis (TB) diagnostic development. Building on this earlier work, this guidance series aims to provide study guidance for performing accuracy studies of novel diagnostic products that may meet the 4 high-priority WHO TPPs and thus enable adequate evidence generation to inform a WHO evidence review process. Diagnostic accuracy studies represent a fundamental step in the validation of all tests. Unfortunately, such studies often have limitations in design, execution, and reporting, leading to low certainty of the evidence about true test performance, which can delay or impede policy and scale-up decisions. This introductory paper outlines the following: (1) the purpose of this series of papers on study guidance; (2) WHO evidence needs and process for the development of policy guidelines for new TB diagnostic tests; and (3) study design considerations, ie, general diagnostic study considerations, intended use of test and role in the clinical pathway, choice of population and setting, index-test specific issues, suitable reference standard and comparators, study flow and specimen issues, and finally key issues beyond accuracy that should be considered. The other 4 papers in this series will provide more detailed guidance for each of the 4 WHO high-priority TPPs. By increasing the clarity around the clinical evaluation needs for tests that have the potential to meet the TPP specifications, we hope to support harmonized evidence generation and enable the WHO review process towards meeting the WHO End TB Strategy targets for reducing the incidence and mortality associated with TB.

scholarly journals Edukasi dan Pemberian Bantuan pada Pasien Tuberkolosis

2018 ◽  
Vol 1 (1) ◽  
pp. 1
Author(s):  
Tohirin Tohirin Tohirin ◽  
Evy Rizki Amaliyah ◽  
Evy Rizki Amaliyah
Keyword(s):  
Pulmonary Tuberculosis ◽  
Infectious Diseases ◽  
World Health Organization ◽  
Health Sciences ◽  
World Health ◽  
World Community ◽  
The World ◽  
Health Organization

Tuberculosis (TB) is one of the deadly infectious diseases which is still a concern of the world community. According to the World Health Organization (WHO) report, in 2013, about 9 million people suffered from tuberculosis and 1.5 million died. This disease attacks various regions in Indonesia, one of them is Tangerang, Banten. Based on data from Puskesmas in Tangerang City, the number of suspect cases of pulmonary tuberculosis in 2015 were 7,455 cases, while the number of new cases of BTA (+) found as many as 1.005 people, and the number of cases of duration of pulmonary tuberculosis were 661 people. Meanwhile, according to gender, found as many as 1017 cases in men and 649 cases in women. This problem is then that pushed the Faculty of Health Sciences Muhammadiyah University Prof. DR. HAMKA reduces the students through the field propagation program. Students educate people about TB disease and raise funds to help people with TB.

Sign in / Sign up

Export Citation Format

Share Document