scholarly journals Influence of Bushen Tiaochong Cycle Therapy on Th1/Th2 Deviation, Sex Hormone Level, and Pregnancy Outcome of Alloimmune Recurrent Spontaneous Abortion

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Peng Wang ◽  
Guilin Jiang ◽  
Wenjuan Ju ◽  
Yaping Cai ◽  
Jinrong Wang ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Success Rate ◽  
Pregnancy Outcome ◽  
Birth Rate ◽  
Hormone Level ◽  
Sex Hormone ◽  
Control Group ◽  
Study Group ◽  
Preterm Birth Rate ◽  
Positive Rate

Objective. To analyze the influence of Bushen Tiaochong cycle therapy on Th1/Th2 deviation, sex hormone level, and pregnancy outcome of alloimmune recurrent spontaneous abortion (RSA). Methods. From August 2018 to April 2020, 130 patients with alloimmune RSA who met the inclusion criteria were randomly divided into the control group (n = 65) and the study group (n = 65). The former received lymphocyte immunotherapy (LIT), and the latter received Bushen Tiaochong cycle therapy on the basis of LIT. The treatment ended at 12 w of pregnancy. The total score of traditional Chinese medicine (TCM) syndromes, Th1 cytokine (IL-2), Th2 cytokine (IL-10), and related hormones (chorionic gonadotropin (hCG) and progesterone (P)) were compared between the two groups before and after treatment. The positive rate of blocking antibody (BA), pregnancy success rate, and preterm birth rate were counted. Result. After treatment, the total score of TCM syndromes, IL-2 level, and Th1/Th2 ratio in the two groups decreased significantly, while the levels of IL-10, hCG, and P increased significantly, and the study group improved significantly compared with the control group ( P < 0.05 ). The positive rate of BA and pregnancy success rate in the study group were higher than those in the control group ( P < 0.05 ). There was no significant difference in the preterm birth rate between the two groups ( P > 0.05 ). Conclusion. On the basis of routine western medicine treatment, a combined application of Bushen Tiaochong cycle therapy can significantly improve the Th1/Th2 deviation, serum sex hormone level, and pregnancy outcome in patients with alloimmune RSA.

scholarly journals Effect of Periodontal Treatment on Preterm Birth Rate: Meta-analysis

2013 ◽  
Vol 4 (4) ◽  
pp. 256-261
Author(s):  
Adel S Alobaid
Keyword(s):  
Preterm Birth ◽  
Treatment Group ◽  
Periodontal Disease ◽  
Birth Rate ◽  
Meta Analysis ◽  
Periodontal Treatment ◽  
Control Group ◽  
Increased Risk ◽  
Significant Difference ◽  
Preterm Birth Rate

ABSTRACT Introduction During pregnancy, the prevalence and severity of gingivitis have been reported to be elevated. Studies suggest that periodontitis is associated with an increased risk of preterm birth (PTB), as well as low birth weight (LBW) and pre-eclampsia. The purpose of this meta-analysis is to determine whether the treatment of periodontal disease by mechanical debridement and oral hygiene instructions during pregnancy will reduce the incidence of PTB < 37 weeks. Materials and methods Literature search was conducted for all clinical trials that related to periodontal disease and PTB from 2005 to 2012. Five were selected based no randomization technique, sample size and treatment approach. There were 2,767 patients randomly assigned to treatment group, in these trials, and 2,592 subjects randomly assigned to control group. Results There were 276 (9.98%) PTBs in treatment group vs 270 (10.42%) in control group. A total of 216 (8%) LBW were seen in experimental groups and 193 (7.5%) in control group. Our results showed no significant difference in the incidence of PTB with or without received periodontal treatment during pregnancy. Risk ratio (RR) was 0.99 (95% CI: 0.74-1.33) (p = 0.97) with moderate heterogeneity 12.33. df = 4 (p = 0.02) with I2= 68%. Experimental groups showed better periodontal health after delivery. Conclusion Periodontal treatment may improve the oral health during pregnancy without affecting the pregnancy outcome however; it did not reduce the incidence of PTB and LBW. Larger meta-analysis with less heterogeneity is needed. How to cite this article Alobaid AS. Effect of Periodontal Treatment on Preterm Birth Rate: Meta-analysis. World J Dent 2013;4(4):256-261.

scholarly journals Validity of pre and post-term birth rates based on the date of last menstrual period compared to early obstetric ultrasonography

2015 ◽  
Vol 31 (4) ◽  
pp. 885-890 ◽  
Author(s):  
Maria Nilza Lima Medeiros ◽  
Nádia Carenina Nunes Cavalcante ◽  
Fabrício José Alencar Mesquita ◽  
Rosângela Lucena Fernandes Batista ◽  
Vanda Maria Ferreira Simões ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Positive Predictive Value ◽  
Predictive Value ◽  
Birth Rate ◽  
Menstrual Period ◽  
Last Menstrual Period ◽  
Birth Rates ◽  
Term Birth ◽  
Preterm Birth Rate ◽  
Obstetric Ultrasonography

The aim of this study was to assess the validity of the last menstrual period (LMP) estimate in determining pre and post-term birth rates, in a prenatal cohort from two Brazilian cities, São Luís and Ribeirão Preto. Pregnant women with a single fetus and less than 20 weeks' gestation by obstetric ultrasonography who received prenatal care in 2010 and 2011 were included. The LMP was obtained on two occasions (at 22-25 weeks gestation and after birth). The sensitivity of LMP obtained prenatally to estimate the preterm birth rate was 65.6% in São Luís and 78.7% in Ribeirão Preto and the positive predictive value was 57.3% in São Luís and 73.3% in Ribeirão Preto. LMP errors in identifying preterm birth were lower in the more developed city, Ribeirão Preto. The sensitivity and positive predictive value of LMP for the estimate of the post-term birth rate was very low and tended to overestimate it. LMP can be used with some errors to identify the preterm birth rate when obstetric ultrasonography is not available, but is not suitable for predicting post-term birth.

scholarly journals Are COVID-19 mitigation measures reducing preterm birth rate in China?

2021 ◽  
Vol 6 (8) ◽  
pp. e006359
Author(s):  
Zheng Bian ◽  
Xiaoxian Qu ◽  
Hao Ying ◽  
Xiaohua Liu
Keyword(s):  
Preterm Birth ◽  
Birth Rate ◽  
Time Window ◽  
Time Windows ◽  
Mitigation Measures ◽  
Late Preterm Birth ◽  
Child Morbidity ◽  
Preterm Birth Rate ◽  
Underlying Mechanisms ◽  
The Impact

ObjectivePreterm birth is the leading cause of child morbidity and mortality globally. We aimed to determine the impact of the COVID-19 mitigation measures implemented in China on 23 January 2020 on the incidence of preterm birth in our institution.DesignLogistic regression analysis was used to investigate the association between the national COVID-19 mitigation measures implemented in China and the incidence of preterm birth.SettingShanghai First Maternity and Infant Hospital, Shanghai China.ParticipantsAll singleton deliveries abstracted from electronic medical record between 1 January 2014 to 31 December 2020.Main outcome measuresPreterm birth rate.ResultsData on 164 107 singleton deliveries were available. COVID-19 mitigation measures were consistently associated with significant reductions in preterm birth in the 2-month, 3-month, 4-month, 5-month time windows after implementation (+2 months, OR 0.80, 95% CI 0.69 to 0.94; +3 months, OR 0.83, 95% CI 0.73 to 0.94; +4 months, OR 0.82, 95% CI 0.73 to 0.92; +5 months, OR 0.84, 95% CI 0.76 to 0.93). These reductions in preterm birth were obvious across various degrees of prematurity, but were statistically significant only in moderate-to-late preterm birth (32 complete weeks to 36 weeks and 6 days) subgroup. The preterm birth difference disappeared gradually after various restrictions were removed (7th–12th month of 2020, OR 1.02, 95% CI 0.94 to 1.11). There was no difference in stillbirth rate across the study time window.ConclusionSubstantial decreases in preterm birth rates were observed following implementation of the national COVID-19 mitigation measures in China. Further study is warranted to explore the underlying mechanisms associated with this observation.

scholarly journals Incidence and trend of preterm birth in China, 1990–2016: a systematic review and meta-analysis

BMJ Open ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. e039303
Author(s):  
Shiwen Jing ◽  
Chang Chen ◽  
Yuexin Gan ◽  
Joshua Vogel ◽  
Jun Zhang
Keyword(s):  
Systematic Review ◽  
Preterm Birth ◽  
Birth Rate ◽  
Meta Analysis ◽  
Northwest China ◽  
Cochrane Library ◽  
Case Control Studies ◽  
Eligibility Criteria ◽  
Rate Of Increase ◽  
Preterm Birth Rate

ObjectivesTo update the WHO estimate of preterm birth rate in China in 1990–2016 and to further explore variations by geographic regions and years of occurrence.DesignSystematic review and meta-analysis.Data sourcesPubmed, Embase, Cochrane Library and Sinomed databases were searched from 1990 to 2018.Eligibility criteriaStudies were included if they provided preterm birth data with at least 500 total births. Reviews, case–control studies, intervention studies and studies with insufficient information or published before 1990 were excluded. We estimated pooled incidence of preterm birth by a random effects model, and preterm birth rate in different year, region and by livebirths or all births in subgroup analyses.ResultsOur search identified 3945 records. After the removal of duplicates and screening of titles and abstracts, we reviewed 254 studies in full text and excluded 182, leaving 72 new studies. They were combined with the 82 studies included in the WHO report (154 studies, 187 data sets in total for the meta-analysis), including 24 039 084 births from 1990 to 2016. The pooled incidence of preterm birth in China was 6.09% (95% CI 5.86% to 6.31%) but has been steadily increasing from 5.36% (95% CI 4.89% to 5.84%) in 1990–1994 to 7.04% (95% CI 6.09% to 7.99%) in 2015–2016. The annual rate of increase was about 1.05% (95% CI 0.85% to 1.21%). Northwest China appeared to have the highest preterm birth rate (7.3%, 95% CI 4.92% to 9.68% from 1990 to 2016).ConclusionsThe incidence of preterm birth in China has been rising gradually in the past three decades. It was 7% in 2016. Preterm birth rate varied by region with the West having the highest occurrence.

Regional Birth Outcomes after the 2011 Great East Japan Earthquake and Tsunami in Miyagi Prefecture

2018 ◽  
Vol 33 (2) ◽  
pp. 215-219 ◽  
Author(s):  
Junichi Sugawara ◽  
Noriyuki Iwama ◽  
Tetsuro Hoshiai ◽  
Hideki Tokunaga ◽  
Hidekazu Nishigori ◽  
...  
Keyword(s):  
Birth Weight ◽  
Preterm Birth ◽  
Low Birth Weight ◽  
Risk Analysis ◽  
Birth Outcomes ◽  
Birth Rate ◽  
Great East Japan Earthquake ◽  
Miyagi Prefecture ◽  
Preterm Birth Rate ◽  
Regional Risk Analysis

AbstractObjectivesThis study was aimed to analyze post-disaster birth outcomes in coastal and inland regions of Miyagi Prefecture, Japan.MethodsPrimary data sets were compiled from birth records of obstetric facilities and 12,808 patients were analyzed for baseline birth outcomes by region. Regional risk analysis of the low-birth-weight rate and premature birth rate were conducted using multi-level logistic regression analysis.ResultsFrom overall baseline birth outcomes, a preterm birth rate was 4.6% and low-birth-weight rate was 8.8%. Regional analysis revealed that a preterm birth rate was 3.2% (coastal) and 5.0% (inland), respectively, and the rate of low birth weight was 6.5% in the coastal and 8.5% in the inland region. In the risk analysis of low-birth-weight rate and preterm birth rate, the risk in the coastal region could not be considered any higher than in the inland region (adjusted odds ratio 0.91 [0.73-1.14] and 0.85 [0.46-1.59], respectively).ConclusionsThe incidence of preterm birth and low birth weight were not adversely affected by the disaster. Early transfer and intensive medical intervention may have led to those findings. Further survey will be necessary to determine the long-term effects in both mothers and children.SugawaraJ, IwamaN, HoshiaiT, TokunagaH, NishigoriH, MetokiH, OkamuraK, YaegashiN. Regional birth outcomes after the 2011 Great East Japan Earthquake and tsunami in Miyagi Prefecture. Prehosp Disaster Med. 2018;33(2):215–219.

scholarly journals Preterm Birth Rate

2018 ◽  
Vol 22 (1) ◽  
pp. 12
Author(s):  
Summer Hunt ◽  
Jennifer P. Hellwig
Keyword(s):  
Preterm Birth ◽  
Birth Rate ◽  
Preterm Birth Rate

scholarly journals When is the ideal time to remove cerclage in cases requiring cesarean hysterectomy for placenta accreta spectrum?

2019 ◽  
Vol 8 (4) ◽  
pp. 1668
Author(s):  
Futa Ito ◽  
Shinya Matsuzaki ◽  
Masayuki Endo ◽  
Tadashi Kimura
Keyword(s):  
Preterm Birth ◽  
Maternal Morbidity ◽  
Birth Rate ◽  
Placenta Accreta ◽  
Cervical Insufficiency ◽  
Short Cervix ◽  
Cesarean Hysterectomy ◽  
Preterm Birth Rate ◽  
Placenta Accreta Spectrum ◽  
The Ideal

Placenta accreta spectrum (PAS) presents one of the highest risks to pregnancy and often requires a cesarean hysterectomy for management, but the challenges associated with this surgery often cause severe obstetric haemorrhaging and high rates of maternal morbidity. Shirodkar cerclage is usually performed in cases with cervical insufficiency, a short cervix with previous preterm birth, etc., to decrease the preterm birth rate. It is recommended that Shirodkar cerclage is removed when the patient approaches term, but the ideal timing of removal for patient for whom cesarean hysterectomy is planned is not clear. Here, authors present a case of PAS in whom Shirodkar cerclage that was difficult to remove at the timing of cesarean hysterectomy. After cesarean hysterectomy, the patient had a vaginal abscess and required antibiotic therapy for approximately two weeks. In the light of our case, authors discuss the timing of removal of cerclage in the cases of PAS.

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