The Prevalence of Depressive Symptoms in Frontotemporal Dementia: A Meta-Analysis

Background: Depression is common in Alzheimer's and vascular dementia and is associated with poorer outcomes; however, less is known about the impact of depression on frontotemporal dementia (FTD). Here, we conducted a meta-analysis of diagnostic methods and the prevalence of depressive symptoms in FTD. Methods: PubMed, EMBASE and PsychINFO were queried for ‘depression' and/or ‘depressive mood' in behavioral- and language-variant FTD. The prevalence and diagnosis of depressive symptoms were extracted from relevant studies and the results pooled using a random-effects model. Results: We included 29 studies in this meta-analysis, with sample sizes ranging from 3 to 73 (n = 870). The omnibus estimated event rate of depressed mood was 0.334 (33%; 95% CI: 0.268-0.407). Symptoms were most commonly assessed via standardized neuropsychiatric rating scales, with other methods including subjective caregiver reports and chart reviews. The study results were heterogeneous due to the variability in diagnostic methods. Conclusions: Depressive symptoms similar to those in other dementias are commonly detected in FTD. However, the diagnostic methods are heterogeneous, and symptoms of depression often overlap with manifestations of FTD. Having a standardized diagnostic approach to depression in FTD will greatly facilitate future research in this area.

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Advances of 2nd Life Applications for Lithium Ion Batteries from Electric Vehicles Based on Energy Demand

Sustainability ◽

10.3390/su13105726 ◽

2021 ◽

Vol 13 (10) ◽

pp. 5726

Author(s):

Aleksandra Wewer ◽

Pinar Bilge ◽

Franz Dietrich

Keyword(s):

Life Cycle ◽

Lithium Ion Batteries ◽

Electric Vehicles ◽

Energy Demand ◽

Lithium Ion ◽

Life Cycles ◽

Future Research ◽

Research Areas ◽

Study Results ◽

The Impact

Electromobility is a new approach to the reduction of CO2 emissions and the deceleration of global warming. Its environmental impacts are often compared to traditional mobility solutions based on gasoline or diesel engines. The comparison pertains mostly to the single life cycle of a battery. The impact of multiple life cycles remains an important, and yet unanswered, question. The aim of this paper is to demonstrate advances of 2nd life applications for lithium ion batteries from electric vehicles based on their energy demand. Therefore, it highlights the limitations of a conventional life cycle analysis (LCA) and presents a supplementary method of analysis by providing the design and results of a meta study on the environmental impact of lithium ion batteries. The study focuses on energy demand, and investigates its total impact for different cases considering 2nd life applications such as (C1) material recycling, (C2) repurposing and (C3) reuse. Required reprocessing methods such as remanufacturing of batteries lie at the basis of these 2nd life applications. Batteries are used in their 2nd lives for stationary energy storage (C2, repurpose) and electric vehicles (C3, reuse). The study results confirm that both of these 2nd life applications require less energy than the recycling of batteries at the end of their first life and the production of new batteries. The paper concludes by identifying future research areas in order to generate precise forecasts for 2nd life applications and their industrial dissemination.

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The Parent–Child Relationship and Sport Parents’ Experiences of Burnout and Engagement

Journal of Clinical Sport Psychology ◽

10.1123/jcsp.2017-0006 ◽

2018 ◽

Vol 12 (2) ◽

pp. 218-233

Author(s):

J.D. DeFreese ◽

Travis E. Dorsch ◽

Travis A. Flitton

Keyword(s):

Youth Sport ◽

Self Report ◽

Future Research ◽

Parent Child Relationship ◽

Psychosocial Experiences ◽

Child Relationship ◽

Study Results ◽

The Impact ◽

Parents Experiences ◽

Parent Child

Burnout and engagement are important psychological outcomes in sport with potential to impact athletes as well as sport parents. The present study examined associations among markers of the sport-based parent child-relationship (warmth and conflict) and parent burnout and engagement in organized youth sport. Youth sport parents (N = 214) aged 26–66 years (M = 43.2,SD = 6.2) completed valid and reliable self-report assessments of study variables. Study results showcased warmth, but not conflict, in the parent–child relationship as a significant negative contributor to global burnout and a significant positive contributor to global engagement in sport parents. Results offer preliminary insight into the impact of parent–child warmth in sport on parents’ experiences of burnout and engagement. Findings have implications for future research and practice designed to promote positive psychosocial experiences for sport families.

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Effectiveness of Mobile Health Interventions on Diabetes and Obesity Treatment and Management: Systematic Review of Systematic Reviews (Preprint)

10.2196/preprints.15400 ◽

2019 ◽

Author(s):

Youfa Wang ◽

Jungwon Min ◽

Jacob Khuri ◽

Hong Xue ◽

Bo Xie ◽

...

Keyword(s):

Glycemic Control ◽

Systematic Reviews ◽

Mobile Health ◽

Weight Reduction ◽

Text Messaging ◽

Meta Analysis ◽

Obesity Treatment ◽

Future Research ◽

The Impact ◽

Diabetes And Obesity

BACKGROUND Diabetes and obesity have become epidemics and costly chronic diseases. The impact of mobile health (mHealth) interventions on diabetes and obesity management is promising; however, studies showed varied results in the efficacy of mHealth interventions. OBJECTIVE This review aimed to evaluate the effectiveness of mHealth interventions for diabetes and obesity treatment and management on the basis of evidence reported in reviews and meta-analyses and to provide recommendations for future interventions and research. METHODS We systematically searched the PubMed, IEEE Xplore Digital Library, and Cochrane databases for systematic reviews published between January 1, 2005, and October 1, 2019. We analyzed 17 reviews, which assessed 55,604 original intervention studies, that met the inclusion criteria. Of those, 6 reviews were included in our meta-analysis. RESULTS The reviews primarily focused on the use of mobile apps and text messaging and the self-monitoring and management function of mHealth programs in patients with diabetes and obesity. All reviews examined changes in biomarkers, and some reviews assessed treatment adherence (n=7) and health behaviors (n=9). Although the effectiveness of mHealth interventions varied widely by study, all reviews concluded that mHealth was a feasible option and had the potential for improving patient health when compared with standard care, especially for glycemic control (−0.3% to −0.5% greater reduction in hemoglobin A<sub>1c</sub>) and weight reduction (−1.0 kg to −2.4 kg body weight). Overall, the existing 6 meta-analysis studies showed pooled favorable effects of these mHealth interventions (−0.79, 95% CI −1.17 to −0.42; I2=90.5). CONCLUSIONS mHealth interventions are promising, but there is limited evidence about their effectiveness in glycemic control and weight reduction. Future research to develop evidence-based mHealth strategies should use valid measures and rigorous study designs. To enhance the effectiveness of mHealth interventions, future studies are warranted for the optimal formats and the frequency of contacting patients, better tailoring of messages, and enhancing usability, which places a greater emphasis on maintaining effectiveness over time.

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Shame Mediates the Relationship Between Pain Invalidation and Depression

Frontiers in Psychology ◽

10.3389/fpsyg.2021.743584 ◽

2021 ◽

Vol 12 ◽

Author(s):

Brandon L. Boring ◽

Kaitlyn T. Walsh ◽

Namrata Nanavaty ◽

Vani A. Mathur

Keyword(s):

Mental Health ◽

Depressive Symptoms ◽

Social Withdrawal ◽

Well Being ◽

Poor Mental Health ◽

Future Research ◽

Internalized Shame ◽

Self Worth ◽

The Impact ◽

The Relationship

The experience of pain is subjective, yet many people have their pain invalidated or not believed. Pain invalidation is associated with poor mental health, including depression and lower well-being. Qualitative investigations of invalidating experiences identify themes of depression, but also social withdrawal, self-criticism, and lower self-worth, all of which are core components of shame. Despite this, no studies have quantitatively assessed the interrelationship between pain invalidation, shame, and depression. To explore this relationship, participants recounted the frequency of experienced pain invalidation from family, friends, and medical professionals, as well as their feelings of internalized shame and depressive symptoms. As shame has been shown to be a precursor for depression, we further explored the role of shame as a mediator between pain invalidation and depressive symptoms. All sources of pain invalidation were positively associated with shame and depressive symptoms, and shame fully mediated the relationship between each source of pain invalidation and depression. Relative to other sources, pain invalidation from family was most closely tied to shame and depression. Overall, findings indicate that one mechanism by which pain invalidation may facilitate depression is via the experience of shame. Future research may explore shame as a potential upstream precursor to depression in the context of pain. Findings provide more insight into the harmful influence of pain invalidation on mental health and highlight the impact of interpersonal treatment on the experiences of people in pain.

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Depressive symptoms and web user experience

PeerJ ◽

10.7717/peerj.4439 ◽

2018 ◽

Vol 6 ◽

pp. e4439 ◽

Cited By ~ 9

Author(s):

Meinald T. Thielsch ◽

Carolin Thielsch

Keyword(s):

Depressive Symptoms ◽

Mental Disorders ◽

User Experience ◽

Structural Equation ◽

Drop Out ◽

Equation Modeling ◽

Subjective Perception ◽

Depression Severity ◽

Symptoms Of Depression ◽

The Impact

Background Depression, as one of the most prevalent mental disorders, is expected to become a leading cause of disability. While evidence-based treatments are not always easily accessible, Internet-based information and self-help appears as a promising approach to improve the strained supply situation by avoiding barriers of traditional offline treatment. User experience in the domain of mental problems therefore emerges as an important research topic. The aim of our study is to investigate the impact of depressive symptoms on subjective and objective measures of web user experience. Method In this two-part online study (Ntotal = 721) we investigate the relationship between depressive symptoms of web users and basic website characteristics (i.e., content, subjective and objective usability, aesthetics). Participants completed search and memory tasks on different fully-functional websites. In addition, they were asked to evaluate the given websites with standardized measures and were screened for symptoms of depression using the PHQ-9. We used structural equation modeling (SEM) to determine whether depression severity affects users’ perception of and performance in using information websites. Results We found significant associations between depressive symptoms and subjective user experience, specifically of website content, usability, and aesthetics, as well as an effect of content perception on the overall appraisal of a website in terms of the intention to visit it again. Small yet significant negative effects of depression severity on all named subjective website evaluations were revealed, leading to an indirect negative effect on the intention to revisit a website via impaired content perceptions. However, objective task performance was not influenced by depressiveness of users. Discussion Depression emerges as capable of altering the subjective perception of a website to some extend with respect to the main features content, usability, and aesthetics. The user experience of a website is crucial, especially as it facilitates revisiting a website and thus might be relevant in avoiding drop-out in online interventions. Thus, the biased impression of persons affected by symptoms of depression and resulting needs of those users should be considered when designing and evaluating E-(Mental)-Health-platforms. The high prevalence of some mental disorders such as depression in the general population stresses the need for further investigations of the found effects.

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Symptoms of Depression in a Large Healthy Population Cohort are related to Subjective Memory Complaints and Memory Performance in Negative Contexts

10.1101/101642 ◽

2017 ◽

Cited By ~ 1

Author(s):

Susanne Schweizer ◽

Rogier A. Kievit ◽

Tina Emery ◽

Richard N. Henson ◽

Keyword(s):

Depressive Symptoms ◽

General Population ◽

Memory Performance ◽

Large Population ◽

Healthy Population ◽

Subjective Memory Complaints ◽

Subjective Memory ◽

Symptoms Of Depression ◽

Memory Complaints ◽

The Impact

AbstractDecades of research have investigated the impact of clinical depression on memory, which has revealed biases and in some cases impairments. However, little is understood about the effects of sub-clinical symptoms of depression on memory performance in the general population. Here we report the effects of symptoms of depression on memory problems in a large population-derived cohort (N = 2544), 87% of whom reported at least one symptom of depression. Specifically, we investigate the impact of depressive symptoms on subjective memory complaints, objective memory performance on a standard neuropsychological task and, in a subsample (n = 288), objective memory in affective contexts. There was a dissociation between subjective and objective memory performance, with depressive symptoms showing a robust relationship with self-reports of memory complaints, even after adjusting for age, gender, general cognitive ability and symptoms of anxiety, but not with performance on the standardised measure of verbal memory. Contrary to our expectations, hippocampal volume (assessed in a subsample, n = 592) did not account for significant variance in subjective memory, objective memory or depressive symptoms. Nonetheless, depressive symptoms were related to poorer memory for pictures presented in negative contexts, even after adjusting for memory for pictures in neutral contexts. Thus the symptoms of depression, associated with subjective memory complaints, appear better assessed by memory performance in affective contexts, rather than standardised memory measures. We discuss the implications of these findings for understanding the impact of depressive symptoms on memory functioning in the general population.

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Research on capital structure determinants: a review and future directions

International Journal of Managerial Finance ◽

10.1108/ijmf-09-2014-0135 ◽

2017 ◽

Vol 13 (2) ◽

pp. 106-132 ◽

Cited By ~ 17

Author(s):

Satish Kumar ◽

Sisira Colombage ◽

Purnima Rao

Keyword(s):

Capital Structure ◽

Meta Analysis ◽

Empirical Studies ◽

Secondary Data ◽

Theoretical Models ◽

Order Theory ◽

Organizational Level ◽

Future Research ◽

Content Type ◽

The Impact

Purpose The purpose of this paper is to study the status of studies on capital structure determinants in the past 40 years. This paper highlights the major gaps in the literature on determinants of capital structure and also aims to raise specific questions for future research. Design/methodology/approach The prominence of research is assessed by studying the year of publication and region, level of economic development, firm size, data collection methods, data analysis techniques and theoretical models of capital structure from the selected papers. The review is based on 167 papers published from 1972 to 2013 in various peer-reviewed journals. The relationship of determinants of capital structure is analyzed with the help of meta-analysis. Findings Major findings show an increase of interest in research on determinants of capital structure of the firms located in emerging markets. However, it is observed that these regions are still under-examined which provides more scope for research both empirical and survey-based studies. Majority of research studies are conducted on large-sized firms by using secondary data and regression-based models for the analysis, whereas studies on small-sized firms are very meager. As majority of the research papers are written only at the organizational level, the impact of leverage on various industries is yet to be examined. The review highlights the major determinants of capital structure and their relationship with leverage. It also reveals the dominance of pecking order theory in explaining capital structure of firms theoretically as well as statistically. Originality/value The paper covers a considerable period of time (1972-2013). Among very few review papers on capital structure research, to the best of authors’ knowledge; this is the first review to identify what is missing in the literature on the determinants of capital structure while offering recommendations for future studies. It also synthesize the findings of empirical studies on determinants of capital structure statistically.

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Improvement of Acupuncture Therapy on Relapse of P atients with G outy A rthritis: A Pairwise and Bayesian Network Meta analysis

Acupuncture & Electro-Therapeutics Research ◽

10.3727/036012921x16298112109457 ◽

2021 ◽

Author(s):

Zhihui Li ◽

Min Chen ◽

Chunzhi Tang

Keyword(s):

Acupuncture Therapy ◽

Bayesian Network ◽

Meta Analysis ◽

Gouty Arthritis ◽

Serum Urate ◽

Cochrane Library ◽

Future Research ◽

Fire Needle ◽

The Impact

Objective: The aim of this study is to investigate the impact of acupuncturetherapy on relapse of patients with gouty arthritis (GA). Methods: “gout ORgouty arthritis” AND “a cupuncture therapy OR acupuncture OR moxibustionOR electroacupuncture OR fire needle OR acupotomology OR blood lettingpuncture OR plum blossom needle” were used as search strategies forsearching related studies. Twenty two studies involving 2394 patient s wereenrolled in this research through the analysis of databases of CNKI, Wanfang,VIP, PubMed, Embase and Cochrane Library. Results: The results of pairwise metaanalysis and network meta analysis (NMA) indicated that patients withacupuncture therapy had a significantly lower relapse rate (RR) compared withthose without acupuncture therapy (OR = 0.21, 95% CI: 0.16 0.26, P <0.00001); the follow up time (TFU) and serum urate concentration (SUA)before treatment had no significant effect on the reductio n of RR caused byacupuncture therapy (P > 0.05); and patients treated with acupuncture plusWestern medicine (WM) had the lowest RR (surface under the cumulativeranking [SUCRA] = 85.0%), followed by acupuncture plus traditional Chinesemedicine (TCM, SUC RA = 73.5%), acupuncture only (SUCRA = 72.8%),fourthly acupuncture plus TCM and WM (SUCRA = 33.0%), then TCM(SUCRA = 28.7%), finally WM (SUCRA = 7.0%). Conclusion: Our findingmay facilitate the application of acupuncture therapy in patients with GA. Ourresearch also offered some information for the future research.

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Comparative Efficacy of Seven Exercise interventions for Symptoms of depression in college students: a network of meta-analysis

10.21203/rs.2.13156/v1 ◽

2019 ◽

Author(s):

Shengyu Guo ◽

Fuying Li ◽

Yan Yang ◽

Ling Chen

Keyword(s):

College Students ◽

Depressive Symptoms ◽

Usual Care ◽

Tai Chi ◽

Exercise Intervention ◽

Meta Analysis ◽

Eligibility Criteria ◽

Exercise Interventions ◽

Symptoms Of Depression ◽

Depressed College Students

Abstract Background Depression among college students is common, exercise interventions are valued as one of the most widely prescribed interventions for depressed college students, however, it is especially difficult for university administrators to determine which exercise intervention is most effective, and efficacy of exercise interventions among depressed college students have not been evaluated. Objectives To systematically review and compare the efficacy of Seven Exercise interventions for Symptoms of depression in college students. Method A network of meta-analysis was conducted to fill the objectives. PubMed, Embase databases, and two Chinese language electronic databases WANFANG and CNKI were searched for the related articles. Eligibility criteria Randomized controlled trials comparing the efficacy of Seven Exercise interventions with usual care of college students with depression were included in the review. Main outcomes The Primary outcome of the present study were standardized mean difference(SMD) and the mean change of depressive symptoms. Results 14 trials were identified, including 2010 depressed college students. The result of direct meta-analysis of this review indicated exercise interventions overall had a significantly lower mean depression scores (SMD=-1.13) when compared with usual care. The result of NMA indicated when comparing with badminton intervention, yoga(SMD=-7.7, 95%CI -14 to -0.93) and tai chi (SMD=-9.4, 95%CI -16 to -2.7) can significantly decrease depression scores of the depressed college students. The rank of seven exercise interventions with respect to efficiently decrease symptom of depressed undergraduates was Tai chi > Yoga > Volleyball > Dance > Run> Basketball> Badminton, respectively. Conclusions Tai chi exhibited the highest probability that became the most efficacy intervention among the comparions, and Yoga showed the second most effectiveness to alleviate depressive symptoms of depressed college students, and dance ranks the third, followed by run, volleyball, basketball, badminton respectively.

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Emergent Issues in the World War Against Global Terrorism

Violent Extremism ◽

10.4018/978-1-5225-7119-3.ch023 ◽

2019 ◽

pp. 429-449

Author(s):

Kenneth David Strang

Keyword(s):

Critical Analysis ◽

Meta Analysis ◽

Contingency Management ◽

Future Research ◽

The World ◽

Culture Of Fear ◽

Emerging Culture ◽

Future Research Directions ◽

Global Terrorism ◽

The Impact

The chapter examines the impact of global terrorism on the top most-impacted nations. Global terrorism continues to impact many nations. There are two impacts – actual attacks causing deaths injuries and/or property damage as well as the emerging culture of fear where human rights have regressed – both impact the risk and contingency management community of practice. The critical analysis method is integrated with a meta-analysis of selected studies. Retrospective and inductive analysis techniques are applied. The risk of global terrorism is reviewed and calculated for the most-impacted nations. The recommendations address the emergent risks for contingency planning specialists, practitioners and researchers to consider. Additionally, future research directions are provided.

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