Contrasting Rates of LINE-1 Amplification among New World Primates of the Atelidae Family

2018 ◽  
Vol 154 (4) ◽  
pp. 217-228 ◽  
Author(s):  
Akash Sookdeo ◽  
Manuel Ruiz-García ◽  
Horacio Schneider ◽  
Stéphane Boissinot
Keyword(s):  
New World ◽  
Single Species ◽  
Spider Monkeys ◽  
New World Monkeys ◽  
South American ◽  
Evolutionary Analysis ◽  
New World Primates ◽  
Mammalian Genomes ◽  
Host Life ◽  
Control Of Transposition

LINE-1 (L1) retrotransposons constitute the dominant category of transposons in mammalian genomes. L1 elements are active in the vast majority of mammals, and only a few cases of L1 extinction have been documented. The only possible case of extinction in primates was suggested for South American spider monkeys. However, these previous studies were based on a single species. We revisited this question with a larger phylogenetic sample, covering all 4 genera of Atelidae and 3 species of spider monkeys. We used an enrichment method to clone recently inserted L1 elements and performed an evolutionary analysis of the sequences. We were able to identify young L1 elements in all taxa, suggesting that L1 is probably still active in all Atelidae examined. However, we also detected considerable variations in the proportion of recent elements indicating that the rate of L1 amplification varies among Atelidae by a 3-fold factor. The extent of L1 amplification in Atelidae remains overall lower than in other New World monkeys. Multiple factors can affect the amplification of L1, such as the demography of the host and the control of transposition. These factors are discussed in the context of host life history.

scholarly journals Referential alarm calling behaviour in New World primates

2012 ◽  
Vol 58 (5) ◽  
pp. 680-697 ◽  
Author(s):  
Cristiane Cäsar ◽  
Klaus Zuberbühler
Keyword(s):  
New World ◽  
General Pattern ◽  
Referential Communication ◽  
New World Monkeys ◽  
Human Language ◽  
New World Primates ◽  
Ample Evidence ◽  
Old World ◽  
Call Type ◽  
Wide Range

Abstract There is relatively good evidence that non-human primates can communicate about objects and events in their environment in ways that allow recipients to draw inferences about the nature of the event experienced by the signaller. In some species, there is also evidence that the basic semantic units are not individual calls, but call sequences and the combinations generated by them. These two findings are relevant to theories pertaining to the origins of human language because of the resemblances of these phenomena with linguistic reference and syntactic organisation. Until recently, however, most research efforts on the primate origins of human language have involved Old World species with comparatively few systematic studies on New World monkeys, which has prevented insights into the deeper phylogenetic roots and evolutionary origins of language-relevant capacities. To address this, we review the older primate literature and very recent evidence for functionally referential communication and call combinations in New World primates. Within the existing literature there is ample evidence in both Callitrichids and Ce-bids for acoustically distinct call variants given to external disturbances that are accompanied by distinct behavioural responses. A general pattern is that one call type is typically produced in response to a wide range of general disturbances, often on the ground but also including inter-group encounters, while another call type is produced in response to a much narrower range of aerial threats. This pattern is already described for Old World monkeys and Prosimians, suggesting an early evolutionary origin. Second, recent work with black-fronted titi monkeys has produced evidence for different alarm call sequences consisting of acoustically distinct call types. These sequences appear to encode several aspects of the predation event simultaneously, notably predator type and location. Since meaningful call sequences have already been described in Old World primates, we suggest that basic combinatorial vocal communication has evolved in the primate lineage long before the advent of language. Moreover, it is possible that some of these communicative abilities have evolved even earlier, or independently, as there is comparable evidence in other taxonomic groups. We discuss these findings in an attempt to shed further light on the primate stock from which human language has arisen.

scholarly journals High susceptibility, viral dynamics and persistence of South American Zika virus in New World monkey species

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Neil Berry ◽  
Deborah Ferguson ◽  
Claire Ham ◽  
Jo Hall ◽  
Adrian Jenkins ◽  
...  
Keyword(s):  
Zika Virus ◽  
New World ◽  
Rhesus Macaques ◽  
World Monkey ◽  
South American ◽  
High Susceptibility ◽  
New World Primates ◽  
Common Marmosets ◽  
World Species ◽  
Old World

Abstract South American Zika virus (ZIKV) recently emerged as a novel human pathogen, linked with neurological disorders. However, comparative ZIKV infectivity studies in New World primates are lacking. Two members of the Callitrichidae family, common marmosets (Callithrix jacchus) and red-bellied tamarins (Saguinus labiatus), were highly susceptible to sub-cutaneous challenge with the Puerto Rico-origin ZIKVPRVABC59 strain. Both exhibited rapid, high, acute viraemia with early neuroinvasion (3 days) in peripheral and central nervous tissue. ZIKV RNA levels in blood and tissues were significantly higher in New World hosts compared to Old World species (Macaca mulatta, Macaca fascicularis). Tamarins and rhesus macaques exhibited loss of zonal occludens-1 (ZO-1) staining, indicative of a compromised blood-brain barrier 3 days post-ZIKV exposure. Early, widespread dissemination across multiple anatomical sites distant to the inoculation site preceded extensive ZIKV persistence after 100 days in New and Old World lineages, especially lymphoid, neurological and reproductive sites. Prolonged persistence in brain tissue has implications for otherwise resolved human ZIKV infection. High susceptibility of distinct New World species underscores possible establishment of ZIKV sylvatic cycles in primates indigenous to ZIKV endemic regions. Tamarins and marmosets represent viable New World models for ZIKV pathogenesis and therapeutic intervention studies, including vaccines, with contemporary strains.

scholarly journals Design of cages and diet for metabolic studies using small new world primates

1971 ◽  
Vol 5 (2) ◽  
pp. 257-265 ◽  
Author(s):  
R. T. Herbert
Keyword(s):  
Stainless Steel ◽  
New World ◽  
New World Monkeys ◽  
New World Primates ◽  
Synthetic Diet ◽  
Metabolic Studies ◽  
Stainless Steel Cage

Metabolic studies using monkeys are difficult. Some of the problems involved are discussed. A stainless-steel cage unit, suitable for metabolic studies using small New World monkeys, is described. The composition and method of preparation of an appropriate pelleted, semi-synthetic diet is also described.

scholarly journals High susceptibility, viral dynamics and persistence of South American Zika virus in New World monkeys

2019 ◽  
Vol 1 (1A) ◽  
Author(s):  
Neil Berry ◽  
Claire Ham ◽  
Jo Hall ◽  
Adrian Jenkins ◽  
Elaine Giles ◽  
...  
Keyword(s):  
Zika Virus ◽  
New World ◽  
New World Monkeys ◽  
South American ◽  
Viral Dynamics ◽  
High Susceptibility

scholarly journals Resolving the organization of the third tier visual cortex in primates: A hypothesis-based approach

2015 ◽  
Vol 32 ◽  
Author(s):  
ALESSANDRA ANGELUCCI ◽  
MARCELLO G.P. ROSA
Keyword(s):  
Visual Cortex ◽  
Experimental Evidence ◽  
Visual Processing ◽  
New World ◽  
Dorsal Stream ◽  
Macaque Monkey ◽  
New World Monkeys ◽  
New World Primates ◽  
Developmental Context ◽  
The Third

AbstractAs highlighted by several contributions to this special issue, there is still ongoing debate about the number, exact location, and boundaries of the visual areas located in cortex immediately rostral to the second visual area (V2), i.e., the “third tier” visual cortex, in primates. In this review, we provide a historical overview of the main ideas that have led to four models of third tier cortex organization, which are at the center of today's debate. We formulate specific predictions of these models, and compare these predictions with experimental evidence obtained primarily in New World primates. From this analysis, we conclude that only one of these models (the “multiple-areas” model) can accommodate the breadth of available experimental evidence. According to this model, most of the third tier cortex in New World primates is occupied by two distinct areas, both representing the full contralateral visual quadrant: the dorsomedial area (DM), restricted to the dorsal half of the third visual complex, and the ventrolateral posterior area (VLP), occupying its ventral half and a substantial fraction of its dorsal half. DM belongs to the dorsal stream of visual processing, and overlaps with macaque parietooccipital (PO) area (or V6), whereas VLP belongs to the ventral stream and overlaps considerably with area V3 proposed by others. In contrast, there is substantial evidence that is inconsistent with the concept of a single elongated area V3 lining much of V2. We also review the experimental evidence from macaque monkey and humans, and propose that, once the data are interpreted within an evolutionary-developmental context, these species share a homologous (but not necessarily identical) organization of the third tier cortex as that observed in New World monkeys. Finally, we identify outstanding issues, and propose experiments to resolve them, highlighting in particular the need for more extensive, hypothesis-driven investigations in macaque and humans.

scholarly journals Simian homologues of human herpesvirus 8

2001 ◽  
Vol 356 (1408) ◽  
pp. 535-543 ◽  
Author(s):  
Blossom Damania ◽  
Ronald C. Desrosiers
Keyword(s):  
Rhesus Monkeys ◽  
Epstein Barr Virus ◽  
New World ◽  
Human Herpesvirus ◽  
Spider Monkeys ◽  
New World Monkeys ◽  
Old World ◽  
Herpesvirus 8 ◽  
Barr Virus ◽  
Epstein Barr

γ–Herpesviruses can be found in most primates including Old World an New World monkeys. The γ– herpesvirinae are grouped into two classes: lymphocryptoviruses (γ 1 ) and rhadinoviruses (γ 2 ). The lymphocryptoviruses include Epstein–Barr virus, lymphocryptovirus of rhesus monkeys, and Herpesvirus papio of baboons. Rhadinoviruses that infect New World monkeys include Herpesvirus saimiri , whose natural host is the squirrel monkey, and Herpesvirus ateles , which infects spider monkeys. Rhadinoviruses that infect hominoids and Old World monkeys include Kaposi's sarcoma–associated herpesvirus, also known as HHV–8, and rhesus monkey rhadinovirus.

scholarly journals Species-Specific Inhibition of Foamy Viruses from South American Monkeys by New World Monkey TRIM5α Proteins

2010 ◽  
Vol 84 (8) ◽  
pp. 4095-4099 ◽  
Author(s):  
Beatriz Pacheco ◽  
Andrés Finzi ◽  
Kathleen McGee-Estrada ◽  
Joseph Sodroski
Keyword(s):  
New World ◽  
World Monkey ◽  
Foamy Virus ◽  
South American ◽  
New World Primates ◽  
Common Marmosets ◽  
Geographic Ranges ◽  
New World Monkey ◽  
Foamy Viruses ◽  
Species Specific

ABSTRACT Foamy virus evolution closely parallels that of the host species, indicating virus-host coadaptation. We studied simian foamy viruses (SFVs) from common marmosets, spider monkeys, and squirrel monkeys, New World monkey (NWM) species that share geographic ranges. The TRIM5α protein from each of these NWM species inhibited the replication of at least one of the SFVs associated with the other two species but did not affect the replication of its own SFV. Thus, TRIM5α has potentially shaped the evolution of SFVs in NWM hosts. Conversely, SFVs may have influenced the evolution of TRIM5 variants in New World primates.

scholarly journals Tissue expression of antigens of ABH blood groups in species of New World Monkeys (Aotus infulatus, Callithrix jacchus, Sapajus apella and Saimiri sciureus)

PLoS ONE ◽  
2020 ◽  
Vol 15 (11) ◽  
pp. e0241487
Author(s):  
Délia Cristina Figueira Aguiar ◽  
Washington Luiz Assunção Pereira ◽  
Gyselly de Cássia Bastos de Matos ◽  
Klena Sarges Marruaz da Silva ◽  
Rosane do Socorro Pompeu de Loiola ◽  
...  
Keyword(s):  
New World ◽  
Genetic Model ◽  
Tissue Expression ◽  
Saimiri Sciureus ◽  
New World Monkeys ◽  
New World Primates ◽  
Human Type ◽  
Sapajus Apella ◽  
Mesodermal Origin ◽  
Species Specific

ABH antigens are histo-antigens, but were first described on the surface of human erythrocytes. They are found in those cells only in great apes and humans, while in more primitive animals they are found in tissues and body fluids. ABH antigens are mainly distributed in tissues that are in contact with the external environment and may serve as ligands for pathogens in tissues or block their connection. Description of the distribution of these molecules in non-human primate tissues is restricted to a few tissues and species. This paper describes the expression of human A, B and H type antigens in different organs from four species of New World Primates, obtained from the Centro Nacional de Primatas, as well as comparing that expression with what has been described for humans. In this study, although the tissue description of the antigens is similar to the genetic model for humans, some differences in expression between some organs from those species and those of humans were found. The differences occurred mainly in endodermal organs that have secretory functions and are probably under the control of the human-type FUT-2 enzyme. In the mesodermal-origin organs there was a reduction or absence of A and B antigen marking, particularly in the H precursor substance, indicating that those organs are under the control of the human-type FUT-1 enzyme. These findings have demonstrated that there is similar ABH antigen reactivity in tissue distribution between the species, although there are some species-specific cases.

scholarly journals Serological evidence of infection with Tana and Yaba pox viruses among several species of monkey

1974 ◽  
Vol 72 (2) ◽  
pp. 245-250 ◽  
Author(s):  
A. W. Downie
Keyword(s):  
South America ◽  
Rhesus Monkeys ◽  
New World ◽  
Neutralizing Antibody ◽  
New World Monkeys ◽  
South American ◽  
Serological Evidence ◽  
Cynomolgus Monkeys

SUMMARYSera from cynomolgus monkeys from Malaysia, from Indian rhesus monkeys, from various species of monkeys from Africa and from South America have been examined for neutralizing antibody to Tanapox and Yaba viruses. No antibody was found to either virus in the sera of rhesus monkeys or South American monkeys. A certain proportion of sera from cynomolgus monkeys and various species of African monkey showed antibody to one or other of the viruses, but few of the positive sera showed antibody to both. The results would seem to suggest that infection with the two viruses is endemic in African and Malaysian monkeys but does not occur or is very rare in Indian rhesus and New World monkeys.

scholarly journals Plasmodium malariae: Parasite and Disease

2007 ◽  
Vol 20 (4) ◽  
pp. 579-592 ◽  
Author(s):  
William E. Collins ◽  
Geoffrey M. Jeffery
Keyword(s):  
Malaria Parasite ◽  
New World ◽  
Plasmodium Malariae ◽  
New World Monkeys ◽  
South American ◽  
Malaria Therapy ◽  
Parasite Detection ◽  
Molecular Studies ◽  
History Of ◽  
Plasmodium Brasilianum

SUMMARY A review of the life history of Plasmodium malariae, the quartan malaria parasite of humans, is presented. Much of the information is based on data obtained from induced infections in humans who were given malaria therapy for the treatment of neurosyphilis between 1940 and 1963. Prepatent periods (i.e., the time until the first day of parasite detection) fever episodes, and maximum parasitemias as a result of infection with P. malariae were obtained and are presented. Experimental and known vectors of the parasite are also discussed. Splenectomized chimpanzees and New World monkeys are readily infected and serve as sources of parasites and antigens for diagnostic and molecular studies. South American monkeys are naturally infected with a parasite known as Plasmodium brasilianum. This parasite appears to be P. malariae that has adapted from humans to grow in monkeys, probably within the last 500 years. Infection with P. malariae is associated with the production of immune complexes in the kidneys and the associated nephrotic syndrome. The essential lesions are a thickening of the glomerular basement membrane and endocapillary cell proliferation. Studies of monkeys infected with P. malariae indicate the same pathology as that demonstrated in humans.

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