scholarly journals Factors Influencing Total Serum IgE in Adults: The Role of Obesity and Related Metabolic Disorders

2020 ◽  
pp. 1-9
Author(s):  
Iago Carballo ◽  
Manuela Alonso-Sampedro ◽  
Elena Gonzalez-Conde ◽  
Juan Sanchez-Castro ◽  
Carmen Vidal ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Body Mass ◽  
Cross Sectional Study ◽  
Normal Weight ◽  
Total Serum ◽  
Cross Sectional ◽  
Positive Skin ◽  
Serum Ige ◽  
Definition Of

<b><i>Background and Aim:</i></b> Few reports have investigated the association between metabolic abnormalities (obesity and related metabolic syndrome) and total serum IgE concentrations. <b><i>Methods:</i></b> This cross-sectional study included a random sample of 1,516 adult individuals (44.7% men, aged 18–91 years, median 52 years) from a single municipality in Spain. Serum IgE was measured in the ADVIA Centaur system. Atopy was defined by the presence of positive skin prick tests to a panel of common aeroallergens in the area. Body mass index and data related to the definition of metabolic syndrome were obtained from all participants. Alcohol consumption, smoking, and regular physical exercise were assessed by a questionnaire. <b><i>Results:</i></b> Atopy (present in 21.9% of 1,514 evaluable individuals) was the strongest factor determining serum IgE concentrations. Male sex and heavy alcohol drinking were independently associated with higher IgE concentrations, particularly in the non-atopic individuals. Body mass index was positively associated with IgE concentrations, independent of potential confounders, although the effect was only evident among non-atopic individuals. In that group, median IgE concentrations in normal-weight and obese individuals were 15 and 24 kU/L, respectively (<i>p</i> &#x3c; 0.001); likewise, obesity was associated with high (&#x3e;100 kU/L) IgE concentrations after adjusting for potential confounders (odds ratio: 1.79, 95% confidence interval: 1.26–2.56, <i>p</i> = 0.001). The presence of metabolic syndrome and its components, particularly abdominal obesity and hyperglycaemia, was also positively and independently associated with higher IgE concentrations in non-atopic individuals. <b><i>Conclusions:</i></b> Obesity and metabolic syndrome components are associated with high total serum IgE concentrations, particularly in non-atopic individuals.

scholarly journals Association between Acne and Body Mass Index: A Hospital Based Cross Sectional Study

2018 ◽  
Vol 16 (1) ◽  
pp. 53-56
Author(s):  
Saraswoti Neupane ◽  
Binamra Basnet ◽  
Tara Devi Sharma
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Acne Vulgaris ◽  
Cross Sectional Study ◽  
Normal Weight ◽  
P Value ◽  
Cross Sectional ◽  
Middle Income ◽  
Medical College ◽  
Middle Income Countries

Introduction: Acne vulgaris is a common and chronic inflammatory skin disease of pilosebaceous unit. Obesity is one of the biggest problems in western life style but nowadays, the problem is increasing even in low and middle-income countries. Body Mass Index (BMI) is used to accurately measure obesity.Objective: To find out the association between different categories of BMI and severity of acne.Materials and methods: This was a cross sectional prospective study conducted in the outpatient department of Gandaki Medical College from January to July, 2017. All the newly diagnosed patients with acne were included in the study. Height and weight of the patients was recorded and BMI was calculated. BMI was categorized as underweight, normal weight, overweight and obese. Type of lesions were noted and severity of acne was graded from 1 to 4.Statistical analysis was performed using SPSS version 17.0 for windows. One-way Analysis of Variance between groups (ANOVA) test was applied. P value of less than 0.05 was considered significant.Results: There were altogether 249 patients with acne. Age of the patients ranged from 10 to 44 years with mean age of 20.82 ±5.9 years. Most of the patients were in the age group of 11-20 years. Female: male ratio was 1:1.4. Majority of patients (65.5%) had normal BMI. Most of the patients had Grade 2 acne (52.6%). There was no significant association between the BMI and severity of acne (p=0.129).Conclusion: There was no significant association between BMI and severity of acne.

scholarly journals Sex Differences in the Influence of Sleep on Body Mass Index and Risk of Metabolic Syndrome in Middle-Aged Adults

Healthcare ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 561
Author(s):  
Hyun-E Yeom ◽  
Jungmin Lee
Keyword(s):  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Body Mass ◽  
Cross Sectional Study ◽  
Poor Sleep ◽  
Middle Aged ◽  
Cross Sectional ◽  
Aged People ◽  
Middle Aged Adults ◽  
The Impact

Poor sleep and obesity are intimately related to cardiovascular diseases. We aimed to examine whether the influence of sleep and body mass index (BMI) on the risk of metabolic syndrome (MetS) differed by sex in middle-aged people. It is a cross-sectional study of 458 Korean participants who completed self-administered surveys; the data were analyzed using the PROCESS macro for SPSS. We found that both sleep and BMI were significant predictors of MetS risk in women, particularly by the role of BMI connecting the impact of sleep to MetS risk. However, the association was not found in men, showing that BMI, but not sleep, was a significant predictor of MetS. This sex-related difference was due to different relationships between sleep and BMI, indicating that BMI was more dependent on sleep quality for women than for men. Therefore, a sex-specific approach to decrease the risk of MetS is warranted.

scholarly journals Correlation of neck circumference with abdominal circumference and body mass index in patients with metabolic syndrome in a hospital from northern Peru: a cross-sectional study

2021 ◽  
Author(s):  
Virgilio E Failoc-Rojas ◽  
Eduardo Díaz-Guevara ◽  
Diego Chambergo-Michilot ◽  
Sandra Zeña-Ñañez ◽  
Karoline Sánchez-Sánchez ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Body Mass ◽  
Cross Sectional Study ◽  
Neck Circumference ◽  
Abdominal Circumference ◽  
Homogeneous Distribution ◽  
Sectional Study ◽  
Cross Sectional ◽  
Anthropometric Parameter

Abstract Background We aimed to evaluate the correlation of neck circumference with abdominal circumference and body mass index in patients with metabolic syndrome in Chocope, Trujillo. Methods This cross-sectional study included patients with untreated metabolic syndrome. Health professionals measured the anthropometric parameters of participants as per the international guidelines. Pearson’s correlation coefficients and single and multiple regression models were used for analysis. Results Data from 250 participants showed homogeneous distribution with respect to age, comorbidities, and biochemical properties according to sex. The mean age was 53.6 years. A positive correlation of neck circumference with abdominal circumference (r = 0.6 and 0.74 for females and males, respectively) and body mass index (r = 0.51 and 0.65 for females and males, respectively) was observed. The linear correlation model showed that a 1-cm increase in neck circumference increased the abdominal circumference by 2.20 cm (p < 0.001) and 2.27 cm (p < 0.001) and body mass index by 0.72 kg/m2 (p < 0.001) and 0.94 kg/m2 (p < 0.001) in males and females, respectively, independent of other variables. Conclusions In participants with metabolic syndrome in this study, neck circumference showed a strong correlation with abdominal circumference and body mass index. This anthropometric parameter can be extremely useful for evaluating obesity among patients with metabolic syndrome.

Balance Assessment Using Multi-Directional Reach Test in Community-Dwelling Elderly People with Different Body Mass Index

2021 ◽  
Vol 104 (12) ◽  
pp. 1908-1912
Keyword(s):  
Body Mass Index ◽  
Elderly People ◽  
Body Mass ◽  
Cross Sectional Study ◽  
Normal Weight ◽  
Community Dwelling ◽  
Balance Assessment ◽  
Weight Group ◽  
Cross Sectional ◽  
Overweight Group

Objective: To assess ability of balance in community-dwelling elderly people with different body mass index (BMI) using multi-directional reach test (MDRT) test. Materials and Methods: The cross-sectional study design was used to evaluate the effects of body mass index (BMI) on ability of balance using MDRT in community-dwelling elderly people. Results: Obese community-dwelling elderly people had the lowest scores in all directions of MDRT when compared with those of normal weight and overweight groups. Furthermore, in overweight group, the scores in all directions of MDRT were significantly reduced compared to those of normal weight group (p<0.05). Moreover, the scores of MDRT were negatively correlated with BMI (p<0.05). Conclusion: Obese and overweight community-dwelling elderly people had decreased ability of balance. Additionally, BMI was negatively correlated with the scores of MDRT in community-dwelling elderly people. Keywords: Body mass index; Multi-directional reach test; Falls; Elderly; Balance

Night eating status according to body mass index of Korean adolescents

2017 ◽  
Vol 47 (1) ◽  
pp. 89-100 ◽  
Author(s):  
Mi-Kyeong Choi ◽  
Yu-Jin Cho ◽  
Myung-Hee Kim ◽  
Yun Jung Bae
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Dietary Habits ◽  
Cross Sectional Study ◽  
Normal Weight ◽  
School Students ◽  
Cross Sectional ◽  
Fast Foods ◽  
Content Type ◽  
Night Eating

Purpose The purpose of this study was to investigate the differences in night eating status according to adolescents’ body mass index (BMI). Design/methodology/approach This was a cross-sectional study that included a total of 688 middle-school students. The subjects were categorized as underweight, normal weight and overweight according to their BMI, and their night eating intake patterns, night eating menu preference and intake frequency were compared and analyzed. Findings With regard to their night eating frequency, 39.8 per cent replied almost never, while 24.3 per cent replied once a week and less and 22.5 per cent replied two to three times a week. Among 11 night eating menus, the preference for fast foods, confectioneries, street foods and noodles was significantly higher in the underweight group than in the overweight group. The intake frequency of night eating menus such as fast foods, confectioneries and breads increased in the following order: overweight, normal and underweight group. The underweight group had a higher frequency of night eating, and they preferred to eat snacks more frequently from their night eating menu. Originality/value In conclusion, it is necessary to form positive dietary habits including nighttime eating for proper dietary management of adolescents.

scholarly journals Analysis of Body Composition of 9- and 10-Year-Old Children in Latvia

Medicina ◽  
2011 ◽  
Vol 47 (10) ◽  
pp. 82
Author(s):  
Helena Karklina ◽  
Peteris Apinis ◽  
Liga Kalnina ◽  
Melita Sauka ◽  
Dzintars Mozgis ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Pediatric Population ◽  
Cross Sectional Study ◽  
Physical Development ◽  
Normal Weight ◽  
Overweight And Obesity ◽  
Cross Sectional ◽  
High Prevalence ◽  
Nutritional Level

Background and Objective. According to the data of epidemiologic research, the prevalence of both excessive and insufficient body weight is increasing in a pediatric population leading to the growing burden of health problems due to these changes. The aim of the study was to understand the current situation of physical development of 9- and 10-year-old boys and girls in Latvia and to estimate the prevalence of underweight, normal weight, overweight, and obesity among young adolescents. Material and Methods. During 2007–2009, a random sample of healthy 9-year-old (n=184) and 10-year-old (n=320) children from all regions and different socioeconomic groups of Latvia was surveyed in a cross-sectional study. The anthropometric measurements of height, weight, 3 circumferences, and 5 skinfolds were performed. The percentage of body fat was calculated by the equation of Slaughter et al. Body mass index and fat mass index were calculated for each respondent. Children were divided into groups according to these indexes. At the age of 9 years, 69.5% of boys had a normal nutritional level either by BMI or FMI, and 54.5% and 72.2% of the girls of the same age had a normal nutritional level by BMI and by FMI, respectively. Obesity according to BMI in 9-year-old boys was found to be 4.7% and in girls 6.1%; according to FMI, 3.7% and 2.3%, respectively. A similar trend was also observed in the cohort of 10-year-old children. Conclusions. The results of the research showed that the problem of high prevalence of Latvian children with underweight is not smaller than the problem of children with obesity. Evaluation of physical development in children based only body mass index may lead to overdiagnosis of obesity.

scholarly journals Metabolic Phenotyping Using Metabolic Syndrome Criteria and Cardiometabolic Disabilities Criteria in Bangladeshi Adult Population

2019 ◽  
Vol 11 (1) ◽  
pp. 1-8
Author(s):  
S Naher ◽  
SS Sejooti ◽  
MM Hoque ◽  
MS Zaman ◽  
H Imam ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Body Mass ◽  
Adult Population ◽  
Normal Weight ◽  
Cross Sectional ◽  
Global Epidemic ◽  
Metabolic Phenotypes ◽  
Metabolically Healthy ◽  
Medical University

Obesity has become a global epidemic and has been found to be associated with numerous comorbidities. Body mass index (BMI) based classification of obesity is simple but co-morbidities do not affect all obese and overweight people. The present study was aimed to find out the frequency of metabolic phenotypes in different BMI groups using metabolic syndrome (MetS) criteria and cardiometabolic disabilities (CA) criteria and also to find out an appropriate method for defining metabolic health among adult population attending out patient department of Bangabandhu Sheikh Mujib Medical University (BSMMU). This cross-sectional analytical study was carried out in the Department of Biochemistry, Bangabandhu Sheikh Mujib Medical University (BSMMU) from March 2016 to February 2017. By non probability sampling, a total of 1023 study subjects were selected from apparently healthy adult individuals attending outpatient department of BSMMU. The study subjects were grouped into three body mass index classes and also further categorized into six groups according to metabolically unhealthy or healthy phenotypes by presence or absence of metabolic syndrome (MetS) criteria as well as cardiometabolic disabilities (CA) criteria respectively. Then agreement among different metabolic phenotypes based on these two criteria were observed. Frequency of different metabolic phenotypes i,e metabolically healthy normal weight (MHNW), metabolically obese normal weight (MONW), metabolically healthy over weight (MHOW), metabolically obese over weight (MOOW), metabolically healthy obese (MHO) and metabolically unhealthy obese (MUO) were 12.3%, 6.9%, 21.4%, 27.7%, 7.7%, 23.9% by MetS criteria and 7.7%, 11.5%, 11.6%, 37.4%, 6.1%, 25.6% by CA criteria respectively. MOOW followed by MUO were found to be predominant among all phenotypes. Fare agreement was found between two criteria in case of normal weight and overweight groups and good agreement was found in case of obese groups. From this study, it may be concluded that, attention should be given to the metabolically obese phenotypes in different BMI classes to reduce co-morbidities. Bangladesh J Med Biochem 2018; 11(1): 1-8

scholarly journals EFFECT OF LEPR AND GR GENE POLYMORPHISMS ON HEALTH STATUS OF MOTHERS WITH METABOLIC DISORDERS AND THEIR NEWBORNS

2020 ◽  
Vol 20 (3) ◽  
pp. 20-25
Author(s):  
V.I. Pokhуlko ◽  
Yu.I. Cherniavska ◽  
S.M. Tsvirenko ◽  
Z.I. Rossokha ◽  
Yu.Yu. Klymchiuk
Keyword(s):  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Body Mass ◽  
Gene Polymorphisms ◽  
Metabolic Disorders ◽  
Cross Sectional Study ◽  
Control Group ◽  
Genetic Determinants ◽  
Cross Sectional ◽  
Prevalence Of Obesity

The high prevalence of obesity and metabolic syndrome throughout the world over the past two decades provided the grounds to the WHO to consider overweight as a non-infectious pandemic. Among the factors that negatively affect the metabolism, result in metabolic disorders and obesity there are genetic, prenatal, diet-related, somatic, psychogenic and others. Analysis of LEPR and GR gene polymorphisms among mothers and their newborns can be an important component in the prediction of metabolic disorders and obesity. The aim of this study was to analyze the presence of clinical and genetic determinants of metabolic syndrome in mothers and their newborns. Materials and methods. A cross-sectional study of 42 pairs of mothers and newborns was performed; we analyzed their anthropometric, clinical and laboratory parameters and, in particular, 2 types of genetic polymorphisms (LEPR rs1137101 and GR, BClI polymorphism). The main group consisted of 15 mother-child pairs, where the woman was clinically obese (body mass index more than 30), the comparison group included 27 mother-child pairs, where the women were overweight (body mass index more than 25). Results. Obese mothers were significantly more likely to have a miscarriage (p = 0.01). Children from obese mothers had significantly higher percentiles of birth weight compared to the control group (60.9 ± 7.7 and 49.75 ± 4.5, respectively, p = 0.05). The GG genotype of the GR gene was associated with more common indications for hospitalization (p = 0.012), rapid delivery (p = 0.01), umbilical cord entanglement around the neck of the foetus (p = 0.012). Among the children- carriers of the GG BclI genotype GR, cardio-metabolic disorders detected by the auscultation of the heart (arrhythmia, functional noise) were found out as significantly more frequent (p = 0.003). Conclusion. The study did not find the associations between LEPR and GR gene polymorphism in obese mothers and the development of overweight in their children, but the study revealed an adverse effect of polymorphic variants on obstetric and gynaecological status of mothers, labour and adaptation of infants in the early neonatal period.

scholarly journals Body mass index, asthma, and respiratory symptoms: a population-based study

2020 ◽  
Vol 46 (1) ◽  
Author(s):  
Elaine Cristina Caon de Souza ◽  
Marcia Margaret Menezes Pizzichini ◽  
Mirella Dias ◽  
Maíra Junkes Cunha ◽  
Darlan Lauricio Matte ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Respiratory Symptoms ◽  
Family Income ◽  
Smoking Status ◽  
Demographic Data ◽  
Population Based ◽  
Cross Sectional Study ◽  
Normal Weight ◽  
Cross Sectional

ABSTRACT Objective: To estimate the prevalence of respiratory symptoms and asthma, according to body mass index (BMI), as well as to evaluate factors associated with physician-diagnosed asthma, in individuals ≥ 40 years of age. Methods: This was a population-based cross-sectional study conducted in Florianópolis, Brazil, with probability sampling. Data were collected during home visits. Demographic data were collected, as were reports of physician-diagnosed asthma, respiratory symptoms, medications in use, and comorbidities. Anthropometric measurements were taken. Individuals also underwent spirometry before and after bronchodilator administration. Individuals were categorized as being of normal weight (BMI < 25 kg/m2), overweight (25 kg/m2 ≥ BMI < 30 kg/m2), or obese (BMI ≥ 30 kg/m2). Results: A total of 1,026 individuals were evaluated, 274 (26.7%) were of normal weight, 436 (42.5%) were overweight, and 316 (30.8%) were obese. The prevalence of physician-diagnosed asthma was 11.0%. The prevalence of obesity was higher in women (p = 0.03), as it was in respondents with ≤ 4 years of schooling (p < 0.001) or a family income of 3-10 times the national minimum wage. Physician-diagnosed asthma was more common among obese individuals than among those who were overweight and those of normal weight (16.1%, 9.9%, and 8.0%, respectively; p = 0.04), as were dyspnea (35.5%, 22.5%, and 17.9%, respectively; p < 0.001) and wheezing in the last year (25.6%, 11.9%, and 14.6%, respectively; p < 0.001). These results were independent of patient smoking status. In addition, obese individuals were three times more likely to report physician-diagnosed asthma than were those of normal weight (p = 0.005). Conclusions: A report of physician-diagnosed asthma showed a significant association with being ≥ 40 years of age and with having a BMI ≥ 30 kg/m2. Being obese tripled the chance of physician-diagnosed asthma.

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