scholarly journals Sex Differences in the Influence of Sleep on Body Mass Index and Risk of Metabolic Syndrome in Middle-Aged Adults

Healthcare ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 561
Author(s):  
Hyun-E Yeom ◽  
Jungmin Lee

Poor sleep and obesity are intimately related to cardiovascular diseases. We aimed to examine whether the influence of sleep and body mass index (BMI) on the risk of metabolic syndrome (MetS) differed by sex in middle-aged people. It is a cross-sectional study of 458 Korean participants who completed self-administered surveys; the data were analyzed using the PROCESS macro for SPSS. We found that both sleep and BMI were significant predictors of MetS risk in women, particularly by the role of BMI connecting the impact of sleep to MetS risk. However, the association was not found in men, showing that BMI, but not sleep, was a significant predictor of MetS. This sex-related difference was due to different relationships between sleep and BMI, indicating that BMI was more dependent on sleep quality for women than for men. Therefore, a sex-specific approach to decrease the risk of MetS is warranted.

BMC Neurology ◽  
2005 ◽  
Vol 5 (1) ◽  
Author(s):  
Michael A Ward ◽  
Cynthia M Carlsson ◽  
Mehul A Trivedi ◽  
Mark A Sager ◽  
Sterling C Johnson

Author(s):  
Yangchang Zhang ◽  
Yang Xiong ◽  
Jia Dong ◽  
Tingting Guo ◽  
Xiaoman Tang ◽  
...  

Background: This paper investigates the problems regarding caffeinated drinks intake, late chronotype, and increased body mass index (BMI) among medical students at a Chinese university. Methods: This cross-sectional study was conducted in 2018 with 616 medical students from Chongqing Medical University in Chongqing, China, whose information were collected by a self-reported questionnaire that included four sections: Demographic characteristics; Caffeinated drinks intake and physical state; Morningness-Eveningness Questionnaire; Depression Anxiety Stress Scale 21. Multiple mediation analyses were conducted to test the impact of late chronotype on increased BMI through caffeinated drinks consumption through two models. Results: The significantly mediated effect of caffeinated drinks consumption was revealed (estimate: −0.01, SE = 0.01, 95% CI [−0.02, −0.01]), and which played a positive role in linking late chronotype (B = −0.01, SE = 0.01, p < 0.001) and increased BMI (B = 1.37, SE = 0.21, p < 0.01), but their significant association did not be found in reversed model. In addition, physical activity and inactivity times demonstrated significant indirect effects in the two models. Conclusions: Interventions should focus on reducing caffeinated drinks intake and sedentary behavior time, enhancing physical activity among medical students.


2007 ◽  
Vol 23 (2) ◽  
pp. 297-304 ◽  
Author(s):  
Rosana Farah Simony ◽  
Suely Godoy Agostinho Gimeno ◽  
Sandra Roberta Gouveia Ferreira ◽  
Laércio Joel Franco

The objective of this study was to evaluate the impact of different body mass index (BMI) ranges associated with the risk of diabetes and hypertension in Japanese-Brazilians. This cross-sectional study was based on data from 1,330 Japanese-Brazilians > 30 years of age who participated in a population-based survey on the prevalence of diabetes mellitus and associated diseases. Glucose tolerance status was classified according to WHO criteria and blood pressure levels according to the VI-JNC. Odds ratios for diabetes and hypertension were calculated for different BMI ranges; for different BMIs, sensitivity and specificity for percentiles 25, 50, 75, 90 and 95 were obtained. Increased odds ratios for diabetes mellitus and hypertension were observed with BMI values > 25kg/m². The 50th percentile corresponded to the highest sensitivity and specificity for the identification of risk for both diseases. Our results suggest that BMI values proposed by WHO should also be useful for this group of Japanese descendants in the assessment of risk for DM and hypertension.


2021 ◽  
Author(s):  
Virgilio E Failoc-Rojas ◽  
Eduardo Díaz-Guevara ◽  
Diego Chambergo-Michilot ◽  
Sandra Zeña-Ñañez ◽  
Karoline Sánchez-Sánchez ◽  
...  

Abstract Background We aimed to evaluate the correlation of neck circumference with abdominal circumference and body mass index in patients with metabolic syndrome in Chocope, Trujillo. Methods This cross-sectional study included patients with untreated metabolic syndrome. Health professionals measured the anthropometric parameters of participants as per the international guidelines. Pearson’s correlation coefficients and single and multiple regression models were used for analysis. Results Data from 250 participants showed homogeneous distribution with respect to age, comorbidities, and biochemical properties according to sex. The mean age was 53.6 years. A positive correlation of neck circumference with abdominal circumference (r = 0.6 and 0.74 for females and males, respectively) and body mass index (r = 0.51 and 0.65 for females and males, respectively) was observed. The linear correlation model showed that a 1-cm increase in neck circumference increased the abdominal circumference by 2.20 cm (p < 0.001) and 2.27 cm (p < 0.001) and body mass index by 0.72 kg/m2 (p < 0.001) and 0.94 kg/m2 (p < 0.001) in males and females, respectively, independent of other variables. Conclusions In participants with metabolic syndrome in this study, neck circumference showed a strong correlation with abdominal circumference and body mass index. This anthropometric parameter can be extremely useful for evaluating obesity among patients with metabolic syndrome.


Author(s):  
Iago Carballo ◽  
Manuela Alonso-Sampedro ◽  
Elena Gonzalez-Conde ◽  
Juan Sanchez-Castro ◽  
Carmen Vidal ◽  
...  

<b><i>Background and Aim:</i></b> Few reports have investigated the association between metabolic abnormalities (obesity and related metabolic syndrome) and total serum IgE concentrations. <b><i>Methods:</i></b> This cross-sectional study included a random sample of 1,516 adult individuals (44.7% men, aged 18–91 years, median 52 years) from a single municipality in Spain. Serum IgE was measured in the ADVIA Centaur system. Atopy was defined by the presence of positive skin prick tests to a panel of common aeroallergens in the area. Body mass index and data related to the definition of metabolic syndrome were obtained from all participants. Alcohol consumption, smoking, and regular physical exercise were assessed by a questionnaire. <b><i>Results:</i></b> Atopy (present in 21.9% of 1,514 evaluable individuals) was the strongest factor determining serum IgE concentrations. Male sex and heavy alcohol drinking were independently associated with higher IgE concentrations, particularly in the non-atopic individuals. Body mass index was positively associated with IgE concentrations, independent of potential confounders, although the effect was only evident among non-atopic individuals. In that group, median IgE concentrations in normal-weight and obese individuals were 15 and 24 kU/L, respectively (<i>p</i> &#x3c; 0.001); likewise, obesity was associated with high (&#x3e;100 kU/L) IgE concentrations after adjusting for potential confounders (odds ratio: 1.79, 95% confidence interval: 1.26–2.56, <i>p</i> = 0.001). The presence of metabolic syndrome and its components, particularly abdominal obesity and hyperglycaemia, was also positively and independently associated with higher IgE concentrations in non-atopic individuals. <b><i>Conclusions:</i></b> Obesity and metabolic syndrome components are associated with high total serum IgE concentrations, particularly in non-atopic individuals.


Author(s):  
V.I. Pokhуlko ◽  
Yu.I. Cherniavska ◽  
S.M. Tsvirenko ◽  
Z.I. Rossokha ◽  
Yu.Yu. Klymchiuk

The high prevalence of obesity and metabolic syndrome throughout the world over the past two decades provided the grounds to the WHO to consider overweight as a non-infectious pandemic. Among the factors that negatively affect the metabolism, result in metabolic disorders and obesity there are genetic, prenatal, diet-related, somatic, psychogenic and others. Analysis of LEPR and GR gene polymorphisms among mothers and their newborns can be an important component in the prediction of metabolic disorders and obesity. The aim of this study was to analyze the presence of clinical and genetic determinants of metabolic syndrome in mothers and their newborns. Materials and methods. A cross-sectional study of 42 pairs of mothers and newborns was performed; we analyzed their anthropometric, clinical and laboratory parameters and, in particular, 2 types of genetic polymorphisms (LEPR rs1137101 and GR, BClI polymorphism). The main group consisted of 15 mother-child pairs, where the woman was clinically obese (body mass index more than 30), the comparison group included 27 mother-child pairs, where the women were overweight (body mass index more than 25). Results. Obese mothers were significantly more likely to have a miscarriage (p = 0.01). Children from obese mothers had significantly higher percentiles of birth weight compared to the control group (60.9 ± 7.7 and 49.75 ± 4.5, respectively, p = 0.05). The GG genotype of the GR gene was associated with more common indications for hospitalization (p = 0.012), rapid delivery (p = 0.01), umbilical cord entanglement around the neck of the foetus (p = 0.012). Among the children- carriers of the GG BclI genotype GR, cardio-metabolic disorders detected by the auscultation of the heart (arrhythmia, functional noise) were found out as significantly more frequent (p = 0.003). Conclusion. The study did not find the associations between LEPR and GR gene polymorphism in obese mothers and the development of overweight in their children, but the study revealed an adverse effect of polymorphic variants on obstetric and gynaecological status of mothers, labour and adaptation of infants in the early neonatal period.


2019 ◽  
Author(s):  
Yang Liu ◽  
Liyan Jiang ◽  
Mengru Zeng

Abstract Background Evidence regarding the association between demographics, socioeconomic status and metabolic syndrome is limited. We aim to investigate whether demographics and socioeconomic status are correlated with metabolic syndrome using data from National Health and Nutrition Examination Survey through 2013/2014 to 2015/2016.Methods A total of 4313 selected participants were included in this cross-sectional study. The independent variables were demographics (age, gender,and race/ethnicity) and socioeconomic status (the ratio of family income to poverty). The dependent variable was metabolic syndrome. The covariates included data release cycle, education level, marital status, dietary data, health insurance, average alcoholic drinks, current smoking, sedentary activity hours, physical activity minutes, and body mass index. Logistic regression analysis was used to evaluate the association between demographics, socioeconomic status and metabolic syndrome.Results In fully-adjusted models, we found that age was positively associated with metabolic syndrome (OR:1.05, 95%CI:1.04-1.05); compared with the male group, female was positively associated with metabolic syndrome in participants with body mass index under 25 kg/m 2 (OR:1.84, 95%CI:1.07-3.18) whereas it was negatively associated with metabolic syndrome in those with body mass index equal to or greater than 30 kg/m 2 (OR:0.62, 95%CI:0.48-0.81); compared with Mexican American, non-Hispanic Asian and other race/ethnicity were positively associated with metabolic syndrome in participants with body mass index under 25 kg/m 2 (OR: 7.30, 95%CI: 1.50-35.62 and OR: 6.09, 95%CI: 1.25-29.74, respectively) while non-Hispanic Black was negatively associated with metabolic syndrome in participants with body mass index equal to or greater than 25 kg/m 2 and less than 30 kg/m 2 (OR:0.58, 95%CI:0.36-0.92); there was no significant association between the ratio of family income to poverty and metabolic syndrome.Conclusions Among the population of nationally representative non-pregnant American adults, there is a correlation between demographics and metabolic syndrome whereas no correlation between socioeconomic status and metabolic syndrome after multivariates adjustment. Healthcare interventions targeting those with metabolic syndrome including older individuals, obese males, along with females, non-Hispanic Asian and other race/ethnicity with BMI under 25 kg/m 2 are required to address these disparities.


PLoS ONE ◽  
2021 ◽  
Vol 16 (10) ◽  
pp. e0257306
Author(s):  
Solomon Mekonnen Abebe ◽  
Abayneh Girma Demisse ◽  
Shitaye Alemu ◽  
Bewketu Abebe ◽  
Nebiyu Mesfin

Background Metabolic syndrome (MetS) is becoming a major public health problem globally; it is clear that the burden of MetS is rapidly increasing the rates of non-communicable diseases (NCD). In Ethiopia studies done so far have shown a large disparity in magnitude of the prevalence of MetS and were mainly institution-based studies. Therefore, this study assess the prevalence of MetS among adults who are residing in Gondar city using Adult Treatment Panel III (ATP III) and the International Diabetes Federation (IDF) assessment tool. The findings are imperative to developing and strengthening national NCD prevention and control programs. Methods This study was conducted in Gondar city Northwest Ethiopia in 2018. It employs a community-based cross-sectional study design among 3,227 individuals 18 years of age or older. Data was collected using the WHO stepwise tool, lipid profile, blood pressure (BP), waist circumference (WC) body mass index (BMI), fasting blood glucose levels (FG), and anthropometric measurements. The prevalence estimation was made along with a 95% confidence interval (CI). The Kappa statistic was used to analyze the statistical agreement between ATP III and IDF definitions of the MetS. Stratified analysis was also performed for description and analysis components using ATP III and IDF as an outcome. Result Of the total study participants (3227), 3059 (94.8%) were included in the final analysis and 52.5% were female. The mean (±SD) age of the study participant was 40.8 years (16.2 ±SD). The overall prevalence of MetS using ATP III was 11.2% [95%CI: 10.1, 12.3] and using IDF was 11.9% [95%CI: 10.8, 13.2]. The sex-specific proportion was high in females rather than males irrespective of the criteria. The overall level of agreement between ATP III and IDF prevalence was 91.7% and the Kappa statistics was 0.594. Older age, low-density lipoprotein cholesterol, body mass index, being female, born in an urban area, consumption of an alcoholic drink in the preceding 30 days, and non-fasting practice was significantly associated with MetS. Conclusion and recommendation There was a higher prevalence of metabolic syndrome among females than males irrespective of metabolic syndrome diagnostic criteria. This also shows good agreement between ATP III and IDF. Being female, urban birthplace, frequent alcohol consumption in the last 30 days, and non-fasting practice are factors associated with higher rates of metabolic syndrome. Hence, awareness campaigns, physical exercise, and nutrition education intervention should be undertaken to promote health behavioral practice.


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