Not So Uncommon Cause of Foot Pain: Cutaneous Hair Splinter of the Sole

2021 ◽  
pp. 1-5
Author(s):  
Ralph M. Trüeb ◽  
Ngoc-Nhi Catharina Luu ◽  
Maria Fernanda Reis Gavazzoni Dias
Keyword(s):  
Stratum Corneum ◽  
Clinical Examination ◽  
Pilonidal Sinus ◽  
Clinical Presentation ◽  
Hair Shaft ◽  
Hair Follicles ◽  
Foot Pain ◽  
Case Presentation ◽  
Animal Hair

<b><i>Introduction:</i></b> A fragment of hair penetrating the skin has been referred to as cutaneous pili migrans in the literature. The condition is regarded rare and the cause unknown. <b><i>Case Presentation:</i></b> A 55-year-old female experienced painful sensations of the sole. Dermoscopy revealed hair fragments penetrating the skin, and histopathology a hair shaft embedded in the stratum corneum. The hairs were mechanically extracted with immediate relief from the pain. <b><i>Discussion and Conclusion:</i></b> Hair splinters of the sole may be a cause of foot pain related to the skin. The hair splinter is yet another form of hair that has embedded itself in the skin. Patients may believe the hair is growing out of the feet, while the soles are among the specialized skin regions that are hairless. The origin of the hair is exogenous and related to an exposure to freshly cut human or animal hair. Cutaneous embedded hairs can be classified based on the clinical presentation, the location, and association with hair follicles into hair splinters, interdigital pilonidal sinus, migrating hair, or ingrown hair. The condition is an important cause of foot pain and should be considered on clinical examination of the skin of the soles.

Intermammary Hidradenitis Suppurativa: Considerations on a Unique Presentation

2021 ◽  
pp. 1-4
Author(s):  
Ana Luísa João ◽  
Nélia Cunha ◽  
Joana Cabete
Keyword(s):  
Surgical Approach ◽  
Inflammatory Disease ◽  
Pilonidal Sinus ◽  
Hidradenitis Suppurativa ◽  
Chronic Inflammatory Disease ◽  
Pilonidal Sinus Disease ◽  
Sinus Disease ◽  
Case Presentation ◽  
Overweight Women

Introduction: Hidradenitis suppurativa (HS) is a potentially disabling chronic inflammatory disease. The intermammary location, not clearly specified in the usual phenotypic classifications, entails significant functional and cosmetic compromise. Case Presentation: Eleven cases of predominantly intermammary disease with multiple fistulization and disfiguring scarring were observed at our Department between January 2016 and March 2020. They were young (mean age = 22 years) obese or overweight women, in which the medical-surgical approach has led to variable results. Discussion/Conclusion: Intermammary HS possibly represents a unique phenotypic presentation, likely to be fistulizing and severe. We believe that anatomo-functional considerations, which can be paralleled to pilonidal sinus disease, contribute to its pathophysiology and striking appearance, and further emphasize the importance of multidisciplinary endeavor to reduce the morbidity associated with this seemingly overlooked location.

Animal hair as a rare cause of pilonidal sinus – a case report

Nowa Medycyna ◽  
2018 ◽  
Vol 25 (4) ◽  
Author(s):  
Paweł Dutkiewicz ◽  
Przemysław Ciesielski
Keyword(s):  
Case Report ◽  
Inflammatory Disease ◽  
Pilonidal Sinus ◽  
Human Hair ◽  
Clinical Case ◽  
Chronic Inflammatory Disease ◽  
Animal Origin ◽  
Safe Procedure ◽  
The World ◽  
Animal Hair

Pilonidal sinus is a chronic inflammatory disease caused by the penetration of hair into the skin. Most often, it is located in the intergluteal area, but it may also develop at a different location. It is usually caused by the penetration of human hair, but animal hair can alaso cause it in rare cases. In the world publications, there are reports of the disease in other, often distant locations, e.g. the suprapubic area, armpit, foot, penis, umbilicus, eyelid, clitoris, intermammary cleft, nose, or scar after removing a Tenckhoff catheter. Usually, it is human hair that causes the formation of pilonidal sinus, but the literature also reports cases caused by animal hair in people who shear sheep. There is no other Polish publication describing pilonidal sinus of animal origin. The article presents a case of atypical pilonidal sinus caused by animal hair, located between the fingers of the patient who is professionally involved in shearing dogs. In the presented clinical case, treatment involved staged fistulotomy with the use of surgical thread. The patient was cured and full function of the hand was preserved. Staged fistulotomy is a safe procedure and can be used to treat pilonidal sinus of the hand.

scholarly journals Morphological characteristics of hair cuticle of clinically healthy domestic cats and dogs

2020 ◽  
pp. 90-95
Author(s):  
O. P. Tymoshenko ◽  
◽  
O. S. Snopenko ◽  
G. A. Papeta ◽  
G. V. Vikulina ◽  
...  
Keyword(s):  
Root Zone ◽  
Clinical Signs ◽  
Morphological Characteristics ◽  
Paint Layer ◽  
Hair Shaft ◽  
Glass Slide ◽  
Domestic Cats ◽  
Hair Samples ◽  
Animal Hair ◽  
Index Value

It is known that the typical for animals of different species the nature of the serrations of the free edges of the scales of the hair cuticle, the density of their location and proximity to each other can determine the species of animal hair samples. The aim of the study was to establish the value of the cuticular index in clinically healthy domestic cats and dogs. The area of the outer surface of the scales of the hair cuticle, or cuticular index, was determined in 20 clinically healthy domestic cats and 18 dogs. Examination of the cuticle was performed using prints on a colorless lacquer, which was applied to a glass slide, pressing the hair to the paint layer. The imprint was examined under a microscope (enlargement ×400) and the cuticular index value was established in the root zone, in the thickest part of the hair shaft, expressed in μM2. It was found that in domestic cats and dogs without clinical signs of any pathology, the values of the cuticular index are in the range of 80-170 and 100-210 μM2accordingly. The value of the cuticular index in domestic cats 60-70 μM2 and in dogs 60-90 μM2in 100 % accidents does not meet in healthy animals. The obtained results can be used as a control during diagnostic activities for numerous variants of internal pathology of domestic cats and dogs, as additional diagnostic tests.

scholarly journals Unusual Site for a White Nodule on the Palatine Tonsil: Presentation, Differential Diagnosis, and Discussion

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Ashwag Yagoub Aloyouny
Keyword(s):  
Differential Diagnosis ◽  
Clinical Presentation ◽  
Surgical Intervention ◽  
Fungal Infections ◽  
The Body ◽  
Palatine Tonsil ◽  
Unusual Site ◽  
Case Presentation ◽  
Lymphoepithelial Cysts ◽  
Malignant Lesions

Introduction. Palatine tonsils are part of the mucosa-associated lymphoid tissue, located in the oropharyngeal region. Although these tissues protect the body from foreign intruders, they are more prone to infections due to their anatomical structure and location. For instance, the differential diagnosis of a white lesion on the palatine tonsil can range from benign to malignant lesions. Oral lymphoepithelial cysts commonly arise as painless, yellowish nodules on the floor of the mouth and the ventral or lateral surface of the tongue. Case Presentation. This paper presents a rare case of an unusual site of a lymphoepithelial cyst (LEC) in the oral cavity. The lesion was located in the tonsil of a 20-year-old woman with a chief complaint of a painless, white lump in the back of the mouth for nine months. Discussion. The differential diagnosis of a white lesion on the palatine tonsil is caused by several factors, such as bacterial, viral, and fungal infections; trauma; stones; cysts; abscess; or cancer. In this case, both the clinical presentation and extra- and intraoral examinations were highly associated with LEC. Oral LEC etiopathogenesis is uncertain, and several theories have been proposed to discuss the causes of LEC. In addition, oral LEC could be monitored without surgical intervention if the nodule is asymptomatic. Conclusion. We emphasize the importance of a thorough clinical examination of oral and oropharyngeal lesions, which are usually neglected.

scholarly journals Hepatitis and Meningoencephalitis due to Enterovirus in a Toddler

2018 ◽  
Vol 3 (1) ◽  
pp. 43
Author(s):  
Mohammad Ali Raza Qizalbash ◽  
Rida Zahra ◽  
Adnan Adil Mithwani ◽  
Anwar Adil Mithwani ◽  
Muaaz Adil Mithwani
Keyword(s):  
Acute Hepatitis ◽  
Clinical Picture ◽  
Clinical Presentation ◽  
Viral Infections ◽  
Coxsackie Virus ◽  
Watery Diarrhea ◽  
Case Presentation

Background: Acute hepatitis caused by viral organisms which are typically implicated in the cases of encephalitis are rarely reported in literature. The presentation of enteroviral meningoencephalitis predominated with the clinical picture of hepatitis has rarely been recorded in populations other than neonates. Case Presentation: A male 2-year-old, presenting with a fever of 38 to 40 °C with chills and rigors, lethargy and drowsiness for 6 days. Along with the nausea, vomiting and watery diarrhea, he developed mouth ulcers (peri-oral vesicles) during the stay at the hospital. After extensive workup he was later diagnosed with meningoencephalitis and acute hepatitis due to Coxsackie virus A. After a stay of more than a month he was successfully treated and discharge. Conclusion: A more thorough evaluation should be carried out for atypical viral infections presenting with clinical presentation of hepatitis and meningoencephalitis.

scholarly journals Interesting Clinical Presentation of Myxoid Liposarcoma of Oropharynx

2013 ◽  
Vol 4 (1) ◽  
pp. 57-58
Author(s):  
Sagaya Raj ◽  
Shuaib Merchant ◽  
Azeem Mohiyuddin ◽  
P Arun
Keyword(s):  
Head And Neck ◽  
Clinical Presentation ◽  
Surgical Excision ◽  
Myxoid Liposarcoma ◽  
Lateral Wall ◽  
Posterior Wall ◽  
Low Grade ◽  
Present Case Report ◽  
Case Presentation ◽  
Histologic Pattern

ABSTRACT Aims To describe an unusual presentation of myxoid liposarcoma of oropharynx and a brief review of literature. Introduction Liposarcomas of head and neck are very rare. Its treatment and prognosis mainly depends on the site and the histologic pattern of the tumor. Case presentation The present case report describes a 65-year-old male with complaints of dysphagia, dyspnea, and a peculiar complaint of mass in the throat which turned out to be a low-grade myxoid liposarcoma arising from right lateral wall of oropharynx extending intraluminal in the esophagus, compressing posterior wall of trachea. The mass was successfully excised surgically and postoperative period was uneventful and patient was asymptomatic 4 months after surgery. Conclusion Myxoid liposarcoma is a rare tumor in head and neck and surgical excision with adequate margin is the treatment of choice. How to cite this article Mohiyuddin A, Raj S, Merchant S, Arun P. Interesting Clinical Presentation of Myxoid Liposarcoma of Oropharynx. Int J Head and Neck Surg 2013;4(1):57-58.

A case of severe SARS-CoV-2 infection with negative nasopharyngeal PCR in pregnancy

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Anna Fuchs ◽  
Lauren Harris ◽  
Ashley Huber ◽  
Mia Heiligenstein ◽  
Cassandra Heiselman ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Clinical Status ◽  
Igg Antibodies ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Case Presentation ◽  
Preterm Premature Rupture ◽  
High Clinical Suspicion ◽  
Maternal Status

Abstract Objectives SARS-CoV-2 remains a pressing issue for our obstetric community during the current pandemic. We present a case of a 22-year-old nulliparous woman 31 weeks pregnant, with significant clinical SARS-CoV-2 disease, in the setting of negative nasopharyngeal PCR testing but positive IgG antibodies. Case presentation This was a 22-year-old patient 31 weeks pregnant who presented with fever, tachycardia, and subsequently preterm premature rupture of membranes (PPROM) and pulmonary emboli with multifocal pneumonia. The patient underwent three negative SARS-CoV-2 tests via nasopharyngeal PCR testing during her hospital stay as well as a negative workup for fever. After a cesarean section for worsening maternal status after 7 days of hospitalization, the patient was admitted for worsening clinical status to the SICU. At the time of SICU admission patient was found to have serum IgG positive antibodies and was managed with intubation, antibiotics, and anticoagulation. Patient eventually left hospital against medical advice on hospital day 16 on oral antibiotics but was found to be recovering well at later outpatient follow up. Conclusions Diagnosis of SARS-CoV-2 remains a complicated picture in the setting of testing limitations. This case highlights an antepartum clinical presentation of severe SARS-CoV-2 and recommends a high clinical suspicion for diagnosis of SARS-CoV-2 and initiation of treatment in the pregnant population, even in the presence of negative nasopharyngeal PCR testing.

scholarly journals The local hypothalamic–pituitary–adrenal axis in cultured human dermal papilla cells

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Eun Young Lee ◽  
You Jin Nam ◽  
Sangjin Kang ◽  
Eun Ju Choi ◽  
Inbo Han ◽  
...  
Keyword(s):  
Hpa Axis ◽  
Hair Loss ◽  
Human Hair ◽  
Stress Hormones ◽  
Dermal Papilla ◽  
Hair Shaft ◽  
Hair Follicles ◽  
Follicle Cells ◽  
Dermal Papilla Cells ◽  
Underlying Mechanisms

Abstract Background Stress is an important cause of skin disease, including hair loss. The hormonal response to stress is due to the HPA axis, which comprises hormones such as corticotropin releasing factor (CRF), adrenocorticotropic hormone (ACTH), and cortisol. Many reports have shown that CRF, a crucial stress hormone, inhibits hair growth and induces hair loss. However, the underlying mechanisms are still unclear. The aim of this study was to examine the effect of CRF on human dermal papilla cells (DPCs) as well as hair follicles and to investigate whether the HPA axis was established in cultured human DPCs. Results CRF inhibited hair shaft elongation and induced early catagen transition in human hair follicles. Hair follicle cells, both human DPCs and human ORSCs, expressed CRF and its receptors and responded to CRF. CRF inhibited the proliferation of human DPCs through cell cycle arrest at G2/M phase and induced the accumulation of reactive oxygen species (ROS). Anagen-related cytokine levels were downregulated in CRF-treated human DPCs. Interestingly, increases in proopiomelanocortin (POMC), ACTH, and cortisol were induced by CRF in human DPCs, and antagonists for the CRF receptor blocked the effects of this hormone. Conclusion The results of this study showed that stress can cause hair loss by acting through stress hormones. Additionally, these results suggested that a fully functional HPA axis exists in human DPCs and that CRF directly affects human DPCs as well as human hair follicles under stress conditions.

Clinical presentation and treatment response to diazoxide in two siblings with congenital hyperinsulinism as a result of a novel compound heterozygous ABCC8 missense mutation

2017 ◽  
Vol 30 (4) ◽  
Author(s):  
Sonya Galcheva ◽  
Violeta Iotova ◽  
Sian Ellard ◽  
Sarah E. Flanagan ◽  
Irina Halvadzhiyan ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Index Patient ◽  
Compound Heterozygous ◽  
Congenital Hyperinsulinism ◽  
Compound Heterozygosity ◽  
Clinical Heterogeneity ◽  
Intravenous Glucose ◽  
Hyperinsulinaemic Hypoglycaemia ◽  
Case Presentation ◽  
Compound Heterozygotes

AbstractBackground:Congenital hyperinsulinism (CHI) can present with considerable clinical heterogeneity which may be due to differences in the underlying genetic etiology. We present two siblings with hyperinsulinaemic hypoglycaemia (HH) and marked clinical heterogeneity caused by compound heterozygosity for the same two novelCase presentation:The index patient is a 3-year-old boy with hypoglycaemic episodes presenting on the first day of life. HH was diagnosed and treatment with intravenous glucose and diazoxide was initiated. Currently he has normal physical and neurological development, with occasional hypoglycaemic episodes detected following continuous fasting on treatment with diazoxide. The first-born 8-year-old sibling experienced severe postnatal hypoglycaemia, generalised seizures and severe brain damage despite diazoxide treatment. The latter was stopped at 6-months of age with no further registered hypoglycaemia. Genetic testing showed that both children were compound heterozygotes for two novelConclusions:These

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