scholarly journals Experimental research on the origin of adhesions in the abdominal cavity after operations

2020 ◽  
Vol 5 (5) ◽  
pp. 504-507
Author(s):  
N. Aleksenko
Keyword(s):  
Experimental Research ◽  
Inflammatory Process ◽  
Abdominal Cavity ◽  
Abdominal Wound ◽  
Middle Line ◽  
Clinical Observations

Fusion of intestines and omentum after surgery, mainly with an abdominal wound, is a frequent phenomenon, proven by a number of clinical observations during repeated operations in the same subjects. Meanwhile, the question of the reasons for such a phenomenon, despite attempts to experimentally resolve it (Snger, Dembowski, Kelterborn), remains open to this day. According to the opinion of the last mentioned authors, the main cause of adhesions in the abdominal cavity after operations is infection, the accretion of the omentum to the middle line is caused by the release of air and the local inflammatory process; further - sloughing of the epithelium and scars of the peritoneum in uncomplicated cases do not give adhesions, ligatures in the abdominal cavity for the most part also do not cause adhesions, but show a tendency to encapsulate.

Two-stage resection of the large intestine with deep peritoneal stitching

1927 ◽  
Vol 23 (2) ◽  
pp. 246-246
Author(s):  
I. Tsimkhes
Keyword(s):  
Colorectal Cancer ◽  
Large Intestine ◽  
Abdominal Cavity ◽  
Parietal Peritoneum ◽  
Abdominal Wound ◽  
Two Stage ◽  
Wound Area

For almost 20 years, in colorectal cancer, where the affected loop and adjacent healthy sections of the large intestine cannot be sufficiently mobilized, even after separation and ligation of the mesentery, the author has been cutting off the parietal peritoneum with fascia of the abdominal wound area and plunging them as deeply into the abdominal cavity as possible.

FEATURES OF ULTRASONIC CHARACTERISTICS OF MESENTERIC LYMPH NODES IN COVID-19 IN CHILDREN WITH ACUTE ABDOMINAL SYNDROME: DESCRIPTION OF CLINICAL CASES

2021 ◽  
Vol 100 (6) ◽  
pp. 178-181
Author(s):  
S.S. Nikitin ◽  
◽  
Yu.G. Pyattoev ◽  
N.B. Guseva ◽  
M.V. Leukhin ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Infection Type ◽  
Abdominal Cavity ◽  
Free Fluid ◽  
Mesenteric Lymph Nodes ◽  
Clinical Observations ◽  
Mesenteric Lymph ◽  
Ultrasound Diagnostics ◽  
Mesenteric Adenitis ◽  
Increased Blood Flow

The authors describe clinical observations of children with acute mesenteric adenitis with PCRconfirmed COVID-19 infection. Attention during ultrasound diagnostics is drawn to the condition of the lymph nodes – mesenteric adenitis in COVID-19 infection was manifested by a significant increase in the size of the nodes – more than 15 mm, a large number of nodes in the cut with a tendency to form a conglomerate, a more rounded shape, significantly increased blood flow, a reaction of the peritoneum in the form its thickening and the presence of free fluid in the abdominal cavity. Unusual for a «ordinary» respiratory viral or intestinal infection type of lymph nodes was the only sign that distinguishes the manifestations of mesenteric infection in COVID-19 infection.

scholarly journals Вміст фактора некрозу пухлин α і трансформуючого фактора росту β1 у сироватці крові хворих на гострий апендицит та абдомінальний туберкульоз

2018 ◽  
Author(s):  
V. M. Akimova
Keyword(s):  
Differential Diagnosis ◽  
Immune System ◽  
Serum Level ◽  
Acute Appendicitis ◽  
Inflammatory Process ◽  
Abdominal Cavity ◽  
Abdominal Tuberculosis ◽  
Urgent Problem ◽  
Elisa Method ◽  
Chronic Inflammatory Process

Introduction. Differential diagnosis of acute appendicitis with abdominal tuberculosis is аn urgent problem of medicine. Тhe immune system is involved іn the pathogenesis of diseases, and cytokines are the regulators of inflammation.The aim of the study – to determine the level of cytokines with the pro- and anti-inflammatory potential of TNFα and TGFβ1 and their correlation in the blood of patients with acute appendicitis and abdominal tuberculosis in order to improve diagnosis and treatment tactics. Research Methods. 51 patients with urgent abdominal pathology were examined, 21 of them with phlegmonous form of acute appendicitis, 30 patients with histologically confirmed diagnosis of abdominal tuberculosis. The content of TNFα и ТGFβ1 in serum was examined by the ELISA method by the reagents “Diaclone” and “DRG Diagnostic”.Results and Discussion. The results of studies have shown that the development of acute and chronic inflammatory process in the abdominal cavity is determined by activation of the macrophage-monocytic system, manifested by a significant increase in the serum level of TNFα. It was established that in patients with abdominal tuberculosis on the background of increased serum level of TNFα ((17.57±1.05) vs. (4.97±0.18) pg/ml) the TGFβ1 level does not differ from the control ((16.52±1.15) vs. (17.94±0.71) ng/ml) at that time, as with acute appendicitis, its level decreased ((11.32±0.65) vs. (17.94±0.71) ng/ml). ТGFβ1/TNFα ratio during the abdominal inflammation was much lower than control, but in abdominal tuberculosis in 1.5 times higher than in acute appendicitis.Conclusions. The serum level and ratio of monocyte-macrofage derived TNFα and ТGFβ1 determines the type of inflammation and may be useful in differential diagnostic of acute appendicitis and abdominal tuberculosis.

scholarly journals Experimental Validation of the Use of Immobilized Form of Miramistin in the Treatment of Advanced Peritonitis

2021 ◽  
Vol 14 (1) ◽  
pp. 53-60
Author(s):  
Boris Semenovich Sukovatykh ◽  
Maria Alekseevna Zatolokina ◽  
Anastasiya Viktorovna Mosolova
Keyword(s):  
Aqueous Solution ◽  
Inflammatory Process ◽  
Comparison Group ◽  
Abdominal Cavity ◽  
Inflammatory Activity ◽  
Sodium Carboxymethylcellulose ◽  
Generalized Peritonitis ◽  
Fecal Suspension ◽  
Anti Inflammatory ◽  
Experimental Group

Introduction. Mortality in generalized peritonitis ranges from 16% to 30%.The aim of research was to experimentally study the effect of the immobilized form of 0.01% miramistin on the basis of sodium salt of carboxymethylcellulose on the course of the inflammatory process in generalized purulent peritonitis.Materials and methods. The experimental study included 288 male Wistar rats, divided into 3 groups, 96 animals each. Animals of the 1st group (control) were exposed to laparotomy and lavage of the abdominal cavity with saline under aseptic conditions 24 hours after the introduction of fecal suspension into the abdominal cavity. Simultaneously, animals of the 2nd group (comparison) underwent a thorough sanitation of the abdominal cavity with saline with removal of purulent effusion and fibrin films at the first stage, and at the second stage, they were injected 5 ml of an aqueous solution of 0.01% miramistin. In animals of the 3rd (experimental) group, 5 ml of 0.01% miramistin gel was evenly distributed over the entire surface of the peritoneum after laparotomy and sanitation of the abdominal cavity with saline solution. The anti-inflammatory activity of the dosage forms was assessed by the dynamics of leukocytosis and the leukocyte index of intoxication, and the anti-inflammatory activity was assessed by the dynamics of the number of microorganisms in the abdominal exudate. The lethality of animals in each group was estimated. The following areas were taken for histological examination: small and large intestine, parietal peritoneum, pancreas, liver.Results. The anti-inflammatory activity of the immobilized form of 0.01% miramistin on the basis of sodium carboxymethylcellulose was superior to the aqueous solution of miramistin 0.01% on the 1st day - 1.3 times, on the 3rd day - 1.6 times, on the 7th day - 1.5 times. Antimicrobial activity in animals of the experimental group was 1.3 times higher on the 1st day, 1.9 times higher on the 3rd day, and 1.7 times higher on the 7th day than in the comparison group. The mortality rate in animals of the experimental group was 1.5 times lower on the 1st day, and 1.4 times lower on the 3rd and 7th days than in animals of the comparison group. On the first day, the morphological picture of peritonitis in animals of the experimental and comparison groups had no significant differences. On the 3rd day in animals of the comparison group, the inflammatory process in the abdominal cavity was pronounced, and in the experimental group, the intensity of peritonitis began to decrease, and by the 7th day it was completely eliminated.Conclusion. The results of the study allow recommending the use of the immobilized form of 0.01% miramistin based on sodium carboxymethylcellulose in the treatment of generalized peritonitis.

scholarly journals Uterine torsion in the mare: diagnosis, operation methods and prognosis

2017 ◽  
Vol 73 (2) ◽  
pp. 124-128
Author(s):  
Maciej Witkowski ◽  
Bernard Turek ◽  
Marek Tischner
Keyword(s):  
Digestive System ◽  
Abdominal Cavity ◽  
Uterine Wall ◽  
The Other ◽  
Midline Laparotomy ◽  
Linea Alba ◽  
Clinical Observations ◽  
Uterine Torsion ◽  
Risk Of Rupture ◽  
Spontaneous Delivery

The aim of the study was to present clinical observations regarding the reposition of uterine torsion in pregnant mares. Treatments were performed in 10 mares hospitalized with a diagnosis of uterine torsion in the period from the 8th to the 11th month of pregnancy, including one mare treated during delivery. In 4 mares, obstetric examination revealed the presence of dead fetuses. In one mare admitted during labor, Kamer's repositioning technique was applied by inserting a hand through the vagina into the uterus. In all other cases, mares underwent surgical repositioning after laparotomy performed in linea alba. In 4 mares, in which the uterine wall was at risk of rupture during handling because of advanced changes, a caesarean section was performed before repositioning. Eight out of the 9 mares survived treatment and recovered without complications. One of five mares in which live fetuses were left, miscarried, while the other four delivered healthy foals. Uterine torsion reposition by midline laparotomy offers the best possibilities for inspecting the abdominal cavity, including the uterus, and for detecting any other abnormalities of the digestive system. In the case of mares in which fetuses were left, spontaneous delivery had no adverse effect on the healing of the wound.

scholarly journals REPARACIÓN ENDOSCÓPICA PREAPONEURÓTICA (REPA) DE LA DIÁSTASIS DE LOS MÚSCULOS RECTOS ASOCIADA O NO A HERNIAS DE LA LÍNEA MEDIA. ESTUDIO MULTICÉNTRICO

2019 ◽  
Author(s):  
Derlin Marcio Juárez Muas ◽  
Ezequiel Palmisano ◽  
Guillermo Pou Santoja ◽  
Salvatore Cuccomarino ◽  
Gabriel Gonzalez Higuera ◽  
...  
Keyword(s):  
Endoscopic Surgery ◽  
Intraoperative Complications ◽  
Abdominal Cavity ◽  
Barbed Suture ◽  
Oblique Muscle ◽  
Middle Line ◽  
Work Activity ◽  
Linea Alba ◽  
Average Return ◽  
Diastasis Recti

AUTORES:Juárez Muas, DerlinM1; Palmisano EzequielM2; Pou Santoja Guillermo3; Cuccomarino Salvatore4; González Higuera Luis G5; Mayo Pablo6; Martínez Maya Juan D7; Domínguez Guillermo8; Ayala Acosta Juan C9; Chichisola Agustín10.1 Salta, Argentina; 2 Rosario, Argentina; 3 Valencia, España; 4 Turín, Italia; 5 Bogotá, Colombia; 6 San Martín de Los Andes, Argentina; 7 Medellín, Colombia; 8 Buenos Aires, Argentina; 9 Bogotá, Colombia; 10 La Plata, Argentina. (Grupo Iberoamericano de Hernias)LUGAR DE TRABAJO: Hospital Público Materno Infantil. 1302 Sarmiento Ave. Salta, Argentina. Tel: 54 9 387- 432500. Ext. 4123 – Cell Phone: 54 9 387- 5175176. Mail: [email protected]: INTRODUCCIÓN:La diástasis de los rectos es una patología habitual en puerperio, asociado a hernias de la línea media. La cirugía endoscópica nos permite restaurar la línea alba. METODO: Estudio multicéntrico y prospectivo entre abril de 2014 y julio de 2018, se operaron 215 pacientes, 94% mujeres con edad promedio de 40 años. Se confirmó el diagnóstico mediante TAC (51,6%) y ecografía (45,5%).RESULTADO: La diástasis de los rectos se asoció con hernias de la línea media en 93,4%.Se diagnosticó diástasis de losrectos <50 mm (55,5%), de 51 a 80 mm (29,6%) y > 81 mm (14,9%).Se realizó plicatura de losrectos con sutura barbada.Se asocióa descarga del músculooblicuo externo en 8,8%, siendo unilateral (8%).Se colocaron mallas de polipropileno ligeras / intermedias (97,3%) y pesadas (2,7%), fijadas con agrafes absorbible (76,2%) , no absorbible (8,8%),adhesivos (7%) y puntos poliglactina 910 (8%). Se colocó drenajes en el 100%. El tiempo quirúrgico promedio 107 minutos.Complicaciones intraoperatorias (1,39%): 2 hipercapnia y 1 lesión térmica de piel umbilical. Complicaciones postoperatoria (12,5%): seroma (9,7%), hematoma preaponeurótico (1,4%).Estancia hospitalaria: 1.6 días.Retorno laboral promedio15 días.Control clínico y ecográfico a los 12 meses (58,6%), sin complicaciones ni recurrencias.CONCLUSION:La cirugía endoscópica nos permitió resolver el defecto parietal con plicatura de los rectos y prótesis preaponeurótica de refuerzo, aumentando la seguridad de la reparación, sin ingresar a la cavidad abdominal, hospitalización reducida, baja tasa de complicaciones, sin recurrencia, evidenciándose la factibilidad, seguridad y reproductibilidad de éste acceso.KEYWORDS: REPARACIÓN ENDOSCÓPICA PREAPONEURÓTICA – PLICATURA DERECTOS - DIÁSTASIS DE RECTOS REPAIR ENDOSCOPIC PREAPONEUROTICA (REPA) OF THE DIASTASIS OF THE RECTI ASSOCIATED OR NOT TO HERNIAS OF THE MIDDLE LINE. MULTI-CENTER STUDYSUMMARY:INTRODUCTION:  Diastasis of the recti is a common pathology in puerperium, associated with middle line hernias. Endoscopic surgery allows us to restore the linea alba.METHOD: Multicenter and prospective study between April 2014 and July 2018, 215 patients were operated, 94% women with an average age of 40 years. The diagnosis was confirmed by CT (51.6%) and ultrasound (45.5%).RESULT: Diastasis of the recti was associated with midline hernias in 93.4%. Diastasis of the recti were diagnosed <50 mm (55.5%), from 51 to 80 mm (29.6%) and> 81 mm (14.9%). Plication of the recti with a barbed suture was performed. It was associated with discharge of the external oblique muscle in 8.8%, being unilateral (8%). Lightweight / intermediate (97.3%) and heavy (2.7%) polypropylene meshes, fixed with absorbable (76.2%), non-absorbable (8.8%), adhesive (7%) and 910 polyglactin stitches were placed (8%). Drainage was placed in 100% of the cases. The surgical time average was 107 minutes. Intraoperative complications (1.39%): 2 hypercapnia and 1 thermal umbilical skin lesion. Postoperative complications (12.5%): seroma (9.7%), preaponeurotic hematoma (1.4%). Hospital stay: 1.6 days. Average return to work activity was of 15 days. Clinical and ultrasound check-up at 12 months (58.6%), without complications or recurrences.CONCLUSION: Endoscopic surgery allowed us to resolve the parietal defect with plication of the recti and reinforcement preapponeurotic prosthesis, increasing the safety of the repair, without entering the abdominal cavity, reduced hospitalization, low rate of complications, without recurrence, evidencing the feasibility, security and reproducibility of this approach.KAYWORDS: PREAPONEUROTIC ENDOSCOPIC REPAIR – RECTI PLICATION - DIASTASIS RECTI

scholarly journals Mite-induced Inflammation: More than Allergy

2012 ◽  
Vol 3 (1) ◽  
pp. ar.2012.3.0025 ◽  
Author(s):  
Mario Sánchez-Borges ◽  
Enrique Fernández-Caldas ◽  
Arnaldo Capriles-Hulett ◽  
Fernan Caballero-Fonseca
Keyword(s):  
Inflammatory Process ◽  
Genetic Factors ◽  
Medical Literature ◽  
Hypersensitivity Reactions ◽  
Atopic Diseases ◽  
Chronic Inflammatory Process ◽  
Clinical Observations ◽  
Cyclooxygenase 1 ◽  
Mite Allergy ◽  
Inflammatory Drugs

Clinical observations have suggested that there is an association of atopic conditions with hypersensitivity reactions to nonsteroidal anti-inflammatory drugs (NSAIDs). This relationship has been especially present in patients allergic to mites. This study was designed to review clinical and experimental evidence linking atopy, mite allergy, and hypersensitivity to aspirin and NSAIDs and discuss the possible mechanisms explaining this association. A review of the medical literature concerning the association of atopic diseases, mite hypersensitivity, and intolerance to NSAIDs using PubMed and other relevant articles is presented. NSAID-sensitive patients are frequently atopic and allergic to mites, and patients who develop oral mite anaphylaxis (OMA) show an increased prevalence of NSAID hypersensitivity. The study of atopic, mite-sensitive patients, who experience urticaria and angioedema when exposed to NSAIDs and patients with OMA suggests an interesting interaction between atopic allergy and disorders of leukotriene synthesis or metabolism. Various mechanisms that could be involved in this interaction are presented, including genetic factors, inhibition of cyclooxygenase-1, and other effects (not related to IgE sensitization) of mite constituents on the immune system. The association of mite hypersensitivity with aspirin/NSAIDs intolerance has been confirmed and provides additional clues to various nonallergic pathways that may contribute to the acute and chronic inflammatory process observed in atopic, mite-allergic, individuals. The clinical relevance of these observations is presently under investigation.

scholarly journals Notes on the fifty operations

2020 ◽  
Vol 5 (5) ◽  
pp. 503-504
Author(s):  
A. Fisher
Keyword(s):  
Abdominal Wall ◽  
Mercuric Chloride ◽  
Chloride Solution ◽  
Abdominal Cavity ◽  
Abdominal Wound ◽  
Absolute Alcohol ◽  
Sulfuric Ether ◽  
Mercuric Chloride Solution ◽  
Entire Thickness ◽  
Boiled Water

At the beginning of his report, the author describes in detail the environment in which he operates. The instruments immediately before the operation are boiled in water for 5 minutes, toothed instruments (tweezers, etc.) are calcined on an alcohol lamp; during the operation, they lie in boiled water. For seams, silk is used, boiled in a 5% carbolic solution and stored in a mixture of equal parts of a 1% (? Ref.) Solution of mercuric chloride and absolute alcohol; is used to apply a catgut disinfected previously lying in the course of 12 hours 0.1% mercuric chloride solution and then kept for several days in a mixture of 1 part ol juniperi and 2 parts alcohol. Sponges are rarely used - they are replaced by tampons from aseptic gauze, which are put into 1/2 solution of mercuric chloride at the time of the operation. The operator and his four assistants put on decontaminated rubber aprons; the sleeves are rolled up above the elbows; hands are washed with green soap and a brush, then with absolute alcohol and mercuric chloride solution. The patient is given a general bath on the eve of the operation and a laxative is given; then, when it is already chloroformed, the hair on mons Veneris is shaved off, the abdominal wall is thoroughly washed with green soap with a brush, sulfuric ether and 1 solution of mercuric chloride. After that, during the operation itself, the author does not use any disinfectant liquids; the abdominal cavity, if necessary, is washed with boiled water. After the operation, the edges of the abdominal wound are washed with mercuric chloride and pulverized with idoform; then sutures are applied, 3-4 deep, covering the entire thickness of the abdominal walls, and many superficial.

scholarly journals Adolf Gessner. - Zwei Fälle von Spontaner Uterusruptur. (Centralbl. F. Gynäk., 1895, No. 2). Two cases of arbitrary uterine rupture

2020 ◽  
Vol 9 (5) ◽  
pp. 492
Author(s):  
N. Kakushkin
Keyword(s):  
Umbilical Cord ◽  
Uterine Rupture ◽  
Abdominal Cavity ◽  
Broad Ligament ◽  
Abdominal Wound ◽  
Fetal Head ◽  
Acute Anemia ◽  
Internal Bleeding ◽  
Transverse Position ◽  
Large Hematoma

1) In 35-year-olds, multiparous, with the correct pelvis, the transverse position of the fetus, the prolapse of the handle and umbilical cord were recognized. During anesthesia and disinfection of the genital parts, a left-sided rupture of the uterus and an upper cut of the vagina was detected, with the exit of the fetal head into the abdominal cavity. Turning and ejecting the child (2600 grm., 48 cm) in asphyxiation, soon revived. After removing it is easy. The gap is tamped. The phenomena of internal bleeding with all the manifestations of acute anemia were soon discovered. Charevosuchenie. There was a large hematoma in the left broad ligament; there is no continuing bleeding. The abdominal wound was sutured. The patient recovered.

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