scholarly journals Exercise tolerance and alcohol intake. Blood pressure relation.

Hypertension ◽  
1990 ◽  
Vol 16 (5) ◽  
pp. 501-507 ◽  
Author(s):  
G H Hartung ◽  
H W Kohl ◽  
S N Blair ◽  
S J Lawrence ◽  
R B Harrist
1994 ◽  
Vol 72 (01) ◽  
pp. 058-064 ◽  
Author(s):  
Goya Wannamethee ◽  
A Gerald Shaper

SummaryThe relationship between haematocrit and cardiovascular risk factors, particularly blood pressure and blood lipids, has been examined in detail in a large prospective study of 7735 middle-aged men drawn from general practices in 24 British towns. The analyses are restricted to the 5494 men free of any evidence of ischaemic heart disease at screening.Smoking, body mass index, physical activity, alcohol intake and lung function (FEV1) were factors strongly associated with haematocrit levels independent of each other. Age showed a significant but small independent association with haematocrit. Non-manual workers had slightly higher haematocrit levels than manual workers; this difference increased considerably and became significant after adjustment for the other risk factors. Diabetics showed significantly lower levels of haematocrit than non-diabetics. In the univariate analysis, haematocrit was significantly associated with total serum protein (r = 0*18), cholesterol (r = 0.16), triglyceride (r = 0.15), diastolic blood pressure (r = 0.17) and heart rate (r = 0.14); all at p <0.0001. A weaker but significant association was seen with systolic blood pressure (r = 0.09, p <0.001). These relationships remained significant even after adjustment for age, smoking, body mass index, physical activity, alcohol intake, lung function, presence of diabetes, social class and for each of the other biological variables; the relationship with systolic blood pressure was considerably weakened. No association was seen with blood glucose and HDL-cholesterol. This study has shown significant associations between several lifestyle characteristics and the haematocrit and supports the findings of a significant relationship between the haematocrit and blood lipids and blood pressure. It emphasises the role of the haematocrit in assessing the risk of ischaemic heart disease and stroke in individuals, and the need to take haematocrit levels into account in determining the importance of other cardiovascular risk factors.


Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Stacy T Sims ◽  
Sandra Tsai ◽  
Marcia L Stefanick

Background: Barriers to physical activity for obese women include overheating, sweating, fatigue, exhaustion, and rapid heart rate. Adipose tissue acts as a thermal insulator, promoting a greater heat load on the nonfat tissues, reducing heat tolerance; exercise causes a rise in body temperature with an inability to dissipate heat contributing to reduced exercise tolerance. With difficulties of thermoregulation in the sedentary obese population, the aspect of attenuating the discomfort thus associated may encourage continuation of exercise. A heat sink applied to palmar surfaces extracts heat and cools the venous blood, reducing thermal strain by enhancing the volume of cooled venous return. We hypothesized that palmar cooling using a rapid thermal exchange device (RTX) during exercise would attenuate the thermal discomfort of exercise of sedentary obese women, improving exercise tolerance. Methods: To examine whether palmar cooling would impact exercise tolerance in obese women, 24 healthy women aged 30–45 years, with no history of long term structured exercise, a body mass of 120–135% above ideal and/or BMI between 30 and 34.9 were recruited. Women were randomized into a cooling (RXT with 16°C water circulating) or a control (RTX with 37°C water circulating) group and attended 3 exercise sessions a week for 3-months (12 weeks). Each session was comprised of 10 min body weight exercises, 25–45 min treadmill walking at 70–85% HRR with the RTX device, and 10 min of core strengthening exercises. The performance marker was a 1.5 mi walk for time; conducted on the first and last days of the intervention. Mixed models were used to model each of the outcomes as a function of thermal strain, time and treatment with covariates of speed, heart rate, distance, and the interaction of the main effects included in the model. Results: Groups were matched at baseline for key variables (time for 1.5 mile walk test, resting and exercising heart rate [HR], blood pressure [BP], waist circumference [WC], body weight, body mass index [BMI]). Among the cooling group, time to complete the 1.5mile walk test was significantly faster (31.6 ± 2.3 vs. 24.6 ± 2.5 min, pre vs. post, P< 0.01). A greater average exercising HR was observed (136 vs. 154 bpm, pre vs. post, P <0.001), with a significant reduction in WC (41.8 ± 3.1 vs. 39.1 ± 2.2 inches, pre vs. post, P< 0.01) and resting BP (139/84 ± 124/70 mmHg, pre vs. post, P < 0.025). There were no significant differences observed in the control group. Conclusion: Results indicate that exercise tolerance in obese women improved with cooling during exercise, more so than those women who did not have cooling. An improvement in blood pressure, heart rate, waist circumference, and overall aerobic fitness was observed. These findings suggest that by reducing thermal discomfort during exercise, tolerance increases, thus improving cardiovascular parameters of obese women.


Hypertension ◽  
2017 ◽  
Vol 70 (suppl_1) ◽  
Author(s):  
A’ja V Duncan ◽  
Wayne Graham ◽  
Liliya Yamaleyeva ◽  
Patricia E Gallagher ◽  
E. Ann A Tallant ◽  
...  

Muscadine grapes ( Vitis rotundifolia ) contain significant levels of polyphenols and their antioxidant capacity may have cardiovascular benefit. We determined the cardiovascular effects of a water soluble muscadine grape extract (MGE) from Piedmont Research & Development Corporation (PRDC, Winston-Salem, NC) that we confirmed has a high content of epicatechin, gallic acid, ellagic acid and procyanidin B2. We hypothesize that this soluble MGE with a potentially high phenolic bioavailability exhibits cardioprotective actions. The effect of long-term MGE intake on blood pressure, cardiac function and exercise tolerance was established in female and male hemizygous (mRen2)27 [mRen2] transgenic rats, an Ang II-AT 1 R-dependent model of hypertension. The mRen2 were administered MGE (8 mg of total phenolics/mL) in the drinking water for 26 weeks (7 female; 7 male); control rats (9 female; 11 male) were given water only. At 40 weeks of age, exercise tolerance was assessed by treadmill (10.2 m x min -1 , 5% inclination). The MGE-treated female mRen2 exhibited a >300% improvement in workload ( W: g X m ) as compared to the untreated group [14551 ± 1313 vs. 4498 ± 481; p<0.01]. MGE intake also extended the time to fatigue (TTF) by 300% in females (4943 ± 443 vs.1615 ± 166 sec; p<0.01). In contrast, chronic intake of MGE had no effect on either exercise workload or TTF in the male mRen2. MGE intake did not alter systolic blood pressure in females (162 ± 3 vs. 166 ± 6 mm Hg, p>0.05) and males (165 ± 5 vs. 160 ± 3 mm Hg) nor alter body weight in either group [females: 334 ± 7 g vs. 339 ± 8 g; males: 613 ± 12 g vs. 590 ± 6 g). Echocardiographic analyses revealed that although the female mRen2 exhibited a higher ejection fraction [73.4±5.1 vs. 42.3±4.5%, n=4-5, p<0.05] and a higher fractional shortening [44.2±4.2 vs. 22.1±2.7%, n=4-5, p<0.05] as compared to males, MGE treatment did not improve these indices in either group. We conclude that the marked improvement in exercise capacity in older adult hypertensive females by chronic MGE intake is not accompanied by augmented cardiac performance, perhaps reflecting the lack of an effect on blood pressure. Thus, it is possible that MGE may directly impact the skeletal muscle to improve exercise in the hypertensive mRen2 females, but not the males.


1988 ◽  
Vol 9 (3) ◽  
pp. 187-208
Author(s):  
Matthew Adeyanju

The study was set up to potentially determine if a stepwise multiple regression model composed of such factors as sociodemographics, attitudes, and behaviors in combination with selected biomedical measures can be used to predict adolescent at risk health conditions such as hypertension and to examine the implications for health education practice. The study population consisted of 650 ninth grade (14–16-year-old) students in the baseline survey (1981) and 606 twelfth grade students in the final survey of 1985. Data collected included clinical measures of height, weight, triceps skinfold thickness, blood pressure, body mass index (BMI), resting pulse, and percent ideal body weight (PIBW). Self-reported health behaviors, attitudes, and sociodemographic variables were also assessed. Principal factor analysis with varimax rotation was employed to determine the grouping of the behavioral/attitudinal test items. Stepwise multiple regression analysis was used to determine the variables' potentials as predictors of blood pressure in adolescents. Significant potential predictors of male diastolic blood pressure included smoking, alcohol intake habits, obesity, pulse, race, age and parents' socioeconomic status; while predictors for the females focused on smoking, alcohol intake habits, stress, obesity, pulse and race. Potential indicators for male systolic blood pressure were smoking, alcohol habits, weight, height, race, parent's socioeconomic status; while smoking, alcohol habits, stress, obesity, pulse and race for the females. Community health promotion, prevention and educational programs directed at these potential predictors need to be implemented to encourage healthful lifestyles in the younger generation.


2000 ◽  
Vol 12 (2) ◽  
pp. 71-78 ◽  
Author(s):  
N.C. Hazarika ◽  
D. Biswas ◽  
K. Narain ◽  
R.K. Phukan ◽  
H.C. Kalita ◽  
...  

A cross sectional study on hypertension was done on 294 subjects aged 30 years and above. 150 households were selected randomly representing 50 households from each locality inhabited exclusively by the rural Mizos, indigenous rural Assamese and the tea-garden workers respectively, in the northeastern region of India. Blood pressure was measured by sphygmo-manorneter in sitting posture. Anthro-pometric measurements were taken using standard procedure for measuring height, weight, waist and hip girth. Information on age, sex, ethnicity, literacy, alcohol intake, smoking pattern, physical activity, occupation, amount of salt consumption was collected using a standard and pre-tested questionnaire. Significant differences were observed in both the systolic and diastolic blood pressure levels among the three different ethnic groups selected for this study ( p<0.0001). Multiple regression analyses indicated that in Mizos, age, waist circumference and alcohol intake were independently associated with increase in systolic blood pressure whereas smoking was found to be negatively associated with systolic blood pressure ( R2=0.391, p<0.001). Factors, which were the best predictors of diastolic blood pressure, were age and body mass index [(kg/m2) ( R2=0.227, p<0.001)]. In the rural Assamese population, the best predictors of systolic blood pressure were age and waist circumference ( R2=0.263, p=0.018). For the diastolic blood pressure, age, alcohol intake and body mass index were important correlates ( R2 = 0.131, p<0.001). In the tea garden community, important predictors of systolic blood pressure were age, gender and marital status ( R2=0.187, p<0.001). On the other hand, age and alcohol intake were best predictors for diastolic blood pressure ( R2=0.09, p<0.001). Asia Pac J Public Health 2000,-12(2): 71-78


Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Mana Kogure ◽  
Tomohiro Nakamura ◽  
Naho Tsuchiya ◽  
Takumi Hirata ◽  
Akira Narita ◽  
...  

Introduction: Recently, the balance between sodium and potassium intake, i.e. sodium-to-potassium (Na/K) ratio, has received significant attention for prevention of hypertension. Previous studies reported the positive association between urinary Na/K (uNa/K) ratio and hypertension. However, even the same uNa/K ratio value, there might be high Na/ high K ratio or low Na/ low K ratio. Hypothesis: We assessed the hypothesis that blood pressure (BP) is higher in high Na/ high K group than that in low Na/ low K group even at the same uNa/K ratio in general population in cross-sectional study. Methods: The subjects were 20 to 74 years old who participated in The Tohoku Medical Megabank Project Community-based Cohort Study. Of these participants, we targeted 54,011 subjects (men: 20,505 women: 33,506 mean age: 59.9 years) who had information of BP, urinary Na and K. We estimated 24-h urinary excretion of Na and K using Tanaka formula. Urinary Na and K were each classified into quartiles (Na; Q1~Q4, K; Q1~Q4), and set all 16 groups of uNa/K ratio by combining Na and K respectively. To assess the relationship between casual uNa/K ratio and BP, we performed an analysis of covariance to calculate the adjusted mean systolic BP (SBP). We included covariate factors as age, sex, BMI and alcohol intake. We also assessed the relationship between uNa/K ratio and SBP using multiple regression analyses adjusted for covariate factors. We stratified the participants into two groups: ‘under treatment for hypertension’ (n=17,091) and ‘without treatment for hypertension (n=36,920)’. Results: The mean of uNa/K ratio for each group of Na (Q1)/K(Q1), Na (Q2)/K(Q2), Na (Q3)/K(Q3) and Na (Q4)/K(Q4) was all 4.0. As previous report showed, higher uNa/K ratio group showed higher SBP and lower uNa/K group showed lower BP. When we compared adjusted mean SBP of Na (Q1)/K(Q1) and Na (Q4)/K(Q4) the value were comparable, but the value were significantly higher in Na (Q4)/K(Q4) group (The adjusted mean SBP of Na (Q1)/K(Q1), Na (Q2)/K(Q2), Na (Q3)/K(Q3) and Na (Q4)/K(Q4) was 123.6, 124.9, 124.7 and 125.5 mmHg, respectively). The uNa/K was significantly positively associated with SBP independently of age, sex, BMI, and alcohol intake. The finding was unchanged the results in under treatment group. Conclusions: BP was significantly higher in high Na/ high K group than in low Na/ low K group even at the same uNa/K ratio. We suggested that not only increasing K intake but also reducing salt is important for preventing hypertension.


2004 ◽  
Vol 27 (9) ◽  
pp. 669-673 ◽  
Author(s):  
Takashi KURIHARA ◽  
Hirofumi TOMIYAMA ◽  
Hideki HASHIMOTO ◽  
Yoshio YAMAMOTO ◽  
Eiji YANO ◽  
...  

1990 ◽  
Vol 43 (1) ◽  
pp. 1-13 ◽  
Author(s):  
Alan R. Dyer ◽  
Gary R. Cutter ◽  
Kiang Liu ◽  
Mary Anne Armstrong ◽  
Gary D. Friedman ◽  
...  

2020 ◽  
Vol 22 (Supplement_H) ◽  
pp. H108-H111
Author(s):  
Piotr Jankowski ◽  
Maciej Banach ◽  
Jolanta Małyszko ◽  
Mirosław Mastej ◽  
Andrzej Tykarski ◽  
...  

Abstract Hypertension remains the most important cardiovascular risk factor in Poland. May Measurement Month is a global initiative organized by the International Society of Hypertension aimed at raising awareness of hypertension and the need for blood pressure (BP) screening and demonstrating the potential of the opportunistic BP measurements. An opportunistic cross-sectional survey of volunteers aged ≥18 was carried out in 146 sites in May 2018. Blood pressure was measured in 6450 subjects (mean age: 41 ± 15 years; 59% females). After multiple imputation, the age and sex standardized systolic and diastolic BP was 126.7/78.4 mmHg in the whole analysed group, 132.8/81.3 mmHg in subjects taking antihypertensive drugs, and 125.7/78.0 mmHg in those not taking any antihypertensive drugs. After multiple imputation, the proportions of subjects with high BP (systolic ≥140 mmHg or diastolic ≥90 mmHg or on treatment for raised BP) were 22.2% in the whole analysed group, 39.2% in subjects taking antihypertensive drugs, and 18.6% those not taking any antihypertensive drugs. Overall, hypertension was present in 32.8% of participants, among them 38.7% were not aware of the disease, 53.1% were taking antihypertensive drugs, and 32.3% had BP controlled to target (&lt;140/90 mmHg). Blood pressure was increasing with increasing body mass index and alcohol intake. Smokers and project participants with diabetes had increased average BP. In conclusion, this project provides additional evidence for a considerable potential for further reduction of cardiovascular risk through improvement in detection and treatment of hypertension in Poland.


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