Abstract P418: Trans Fats Consumption Linked to Higher BMI

Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Beatrice A Golomb ◽  
Hayley J Koslik
Keyword(s):  
Clinical Trial ◽  
Statistical Significance ◽  
Depression Scale ◽  
Fat Deposition ◽  
Metabolic Effects ◽  
Trans Fats ◽  
Food Frequency ◽  
Men And Women ◽  
Adult Men ◽  
Age And Sex

Background: Increasing evidence suggests that factors beyond calorie balance may affect fat deposition (consider environmental obesogens like bisphenol A). Trans fats are prooxidant, proinflammatory, have shown adverse metabolic effects and increased fat deposition in animals. Goal: To assess the relation of dietary trans fatty acid ( dTFA ) consumption to BMI in humans. Method: Subjects were 1018 adult men and women clinical trial screenees (age 20-85, without known diabetes, CVD, with screening LDL 115-190mg/dL). Height and weight were measured at screening and BMI calculated. The Fred Hutchinson Food Frequency Questionnaire provided data on dTFA (gm/d) and calories. Surveys elicited activity, and chocolate consumption (times/week, previously linked favorably in this sample to BMI). Mood (adversely linked to dTFA in this sample and in literature) was assessed by the CES-D (depression scale). Regression assessed the relation of BMI (outcome) to dTFA, unadjusted and in models adjusted for age and sex, calories and activity, chocolate consumption, and mood. Results: Higher dTFA was linked with higher BMI across adjustment models, with strong statistical significance. The coefficient was strengthened, not attenuated, when calories and activity were considered. Each additional gram/day of dTFAs was associated with around 0.4 points greater BMI. Discussion: These findings extend adverse metabolic associations of dTFA, and comport with evidence suggesting that composition of calories, as well as their number, has relevance to BMI.

scholarly journals Depressive Symptoms and Relationship Between Genders: Differences in Young Adults in a Randomized Clinical Trial

2017 ◽  
Vol 27 (67) ◽  
pp. 3-9 ◽  
Author(s):  
Mariane Ricardo Acosta Lopez Molina ◽  
Karen Jansen ◽  
Ricardo Tavares Pinheiro ◽  
Ricardo Azevedo da Silva ◽  
Miguel Bezerra dos Passos ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Depressive Symptoms ◽  
Randomized Clinical Trial ◽  
Rating Scale ◽  
Behavioral Therapy ◽  
Post Intervention ◽  
Major Depressive ◽  
Men And Women ◽  
Adult Men ◽  
High Prevalence

Abstract: Depression has a high prevalence in the general population, especially among women. There is no consensus in the scientific literature about differences between men and women in the manifestations of depressive symptoms, nor about psychotherapy indications according to gender. This research aimed to verify differences in depressive symptoms and symptoms improvement between young adult men and women with current Major Depressive Disorder and to identify differences between two brief Cognitive Psychotherapy models. Randomized clinical trial in which participants were randomized between: Cognitive Behavioral Therapy and Narrative Cognitive Therapy. Depressive symptoms pre and post-intervention were evaluated using the Hamilton Depression Rating Scale. The sample was composed of 25 men and 95 women. Genital symptoms and insight were significantly different between genders. Concerning improvement in symptoms according to the psychotherapy model, CBT presented a trend toward being more effective in men. Therefore, the symptoms and improvement in depressive symptoms are manifested differently between genders.

scholarly journals Trans Fats Consumption and Body Mass Index in Cross Sectional Analysis

2021 ◽  
Author(s):  
Beatrice A. Golomb ◽  
Arthur Pavlovsky ◽  
Hayley J. Koslik
Keyword(s):  
Body Mass Index ◽  
Waist Circumference ◽  
Body Mass ◽  
Fat Deposition ◽  
Metabolic Effects ◽  
Cross Sectional ◽  
Trans Fats ◽  
Cross Sectional Analysis ◽  
Consumption Frequency ◽  
Sectional Analysis

AbstractBackgroundTrans fats remain on the market in parts of the world. Emerging evidence suggests that factors beyond calorie balance may affect fat deposition and body mass index (BMI). Trans fats are prooxidant, proinflammatory, and have shown adverse metabolic effects and increased fat deposition in animals.ObjectiveTo assess the relation of dietary trans fatty acid consumption (dTFA) to BMI in humans.DesignCross-sectional analysis of baseline data from a broadly-sampling study.SettingCommunity-dwelling adults from Southern California.Participants1018 adult men and women aged 20-85 without known diabetes, CVD, or cancer, with screening LDL 115-190mg/dL. Women of procreative potential and children were excluded.MeasurementsHeight, weight, and waist circumference were measured, and BMI calculated (kg/m2). The Fred Hutchinson Food Frequency Questionnaire provided data on dTFA (grams/day) and calories consumed. Additional covariates included activity, chocolate consumption frequency, and mood. Regression assessed the relation of BMI (outcome) to dTFA, unadjusted and in models adjusting for age and sex, and adding calories and activity, chocolate consumption frequency, and mood.ResultsHigher dTFA was associated with higher BMI and waist circumference. The coefficient was strengthened, not attenuated, with adjustment for calories and activity, and other assessed covariates. In the fully adjusted model, each gram/day of dTFAs was associated with 0.44 higher BMI (SE=0.12;95%CI=0.21,0.67); P<0.001 and 1cm greater waist circumference (SE=0.35;95%CI=0.37,1.7); P=0.003.ConclusionFindings relating greater dTFA to higher BMI in humans comport with experimental data in animals, extend adverse metabolic associations of dTFA, and buttress evidence that foods’ composition, as well as caloric number, bears on BMI. Findings are cross-sectional but strength and consistency of association, biological gradient, and biological plausibility add “weight” to the prospect of a causal connection.Strengths and limitations of this studyFindings are cross-sectional and rely on dietary recall.Observational studies carry risks of bias and confounding; but randomized trials are problematic where products with potential for harm are under evaluation.Although some nations have implemented plans to remove or reduce dTFAs from the food supply, dTFA remain on the market in other nations, rendering findings of continued interest.The association of increased dTFA with increased BMI and waist circumference fits with other documented adverse metabolic associations of dTFA and is buttressed by experimental documentation that dTFA (without excess calories) increases visceral fat in animals, supporting prospects for causality in the observed association.

879: Sensitivity Mapping of Adult Men and Women Based on Sagasf Survey

2004 ◽  
Vol 171 (4S) ◽  
pp. 233-233
Author(s):  
Justine M. Schober ◽  
Heino F.L. Meyer-Bahlburg ◽  
Philip G. Ransley
Keyword(s):  
Men And Women ◽  
Adult Men

Alcohol use and aggressive behavior among adult men and women

2010 ◽  
Author(s):  
Kenneth Leonard ◽  
B. Quigley ◽  
M. Testa ◽  
R. Houston
Keyword(s):  
Alcohol Use ◽  
Aggressive Behavior ◽  
Men And Women ◽  
Adult Men

Risk of Depression in Adolescents and Young Adults with Rheumatic Diseases

2020 ◽  
Vol 62 (1) ◽  
pp. 38-42
Author(s):  
Anna Kostiukow ◽  
Wojciech Strzelecki ◽  
Mateusz W. Romanowski ◽  
Marta Rosołek ◽  
Ewa Mojs ◽  
...  
Keyword(s):  
Young Adults ◽  
Young People ◽  
Rheumatic Diseases ◽  
Disease Risk ◽  
Statistical Significance ◽  
Energy Levels ◽  
Young Patients ◽  
Depression Scale ◽  
Adolescents And Young Adults ◽  
Control Group

Introduction: The study is aimed at drawing the attention of the medical environment to the mental health aspects of young patients as a factor that significantly influences the efficiency of their rheumatic disease treatment. Aim: This paper is to check the risk of depression among a group of adolescents and young adults with rheumatic diseases. Material and Methods: The study was conducted among a group of 68 late adolescents and young adults (18-22 years old) with rheumatic diseases. The control group consisted of 102 young people (18-22 years old) without a diagnosed chronic disease. Risk of depression was measured using a screening tool – the Kutcher Adolescent Depression Scale (KADS). Results: The analysis showed that the probability of depression in the study group was 35.3%. In the control group, this rate was 19.6%. The results were statistical significance (p=0.028). Conclusions: The results of this study prove that the risk of depression among adolescents and young adults with rheumatic diseases is significantly higher than in healthy young people. The highest risk of depression is related to feeling tired, fatigue, low energy levels and lack of motivation as well as feeling worried, nervous, panicky, tense, keyed-up and anxious.

scholarly journals Dietary Fat Chain Length, Saturation, and PUFA Source Acutely Affect Diet-Induced Thermogenesis but Not Satiety in Adults in a Randomized, Crossover Trial

Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2615
Author(s):  
Bret M. Rust ◽  
Susan K. Raatz ◽  
Shanon L. Casperson ◽  
Sara E. Duke ◽  
Matthew J. Picklo
Keyword(s):  
Energy Expenditure ◽  
Dietary Fatty Acids ◽  
Degree Of Saturation ◽  
Postprandial Period ◽  
Men And Women ◽  
Adult Men ◽  
Randomized Crossover Trial ◽  
Structural Differences ◽  
Diet Induced Thermogenesis ◽  
Postprandial Energy Expenditure

Structural differences in dietary fatty acids modify their rate of oxidation and effect on satiety, endpoints that may influence the development of obesity. This study tests the hypothesis that meals containing fat sources with elevated unsaturated fats will result in greater postprandial energy expenditure, fat oxidation, and satiety than meals containing fats with greater saturation. In a randomized, 5-way crossover design, healthy men and women (n = 23; age: 25.7 ± 6.6 years; BMI: 27.7 ± 3.8 kg/m2) consumed liquid meals containing 30 g of fat from heavy cream (HC), olive oil (OO), sunflower oil (SFO), flaxseed oil (FSO), and fish oil (FO). Energy expenditure and diet-induced thermogenesis (DIT) were determined by metabolic rate over a 240 min postprandial period. Serum concentrations of ghrelin, glucose, insulin, and triacylglycerol (TAG) were assessed. DIT induced by SFO was 5% lower than HC and FO (p = 0.04). Energy expenditure and substrate oxidation did not differ between fat sources. Postprandial TAG concentrations were significantly affected by fat source (p = 0.0001). Varying fat sources by the degree of saturation and PUFA type modified DIT but not satiety responses in normal to obese adult men and women.

scholarly journals Evolution of the prevalence of obesity in the adult population in France, 2013–2016: the Constances study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sébastien Czernichow ◽  
Adeline Renuy ◽  
Claire Rives-Lange ◽  
Claire Carette ◽  
Guillaume Airagnes ◽  
...  
Keyword(s):  
Linear Trend ◽  
Adult Population ◽  
Age Groups ◽  
French Population ◽  
Obesity Prevalence ◽  
Point Change ◽  
Men And Women ◽  
Class 1 ◽  
Prevalence Of Obesity ◽  
Age And Sex

AbstractThis study provides trends in obesity prevalence in adults from 2013 to 2016 in France. 63,582 men and women from independent samples upon inclusion from the Constances cohort were included. Anthropometrics were measured at Health Screening Centers and obesity defined as a Body mass index (BMI) ≥ 30 kg/m2; obesity classes according to BMI are as follows: class 1 [30–34.9]; class 2 [35–39.9]; class 3 [≥ 40 kg/m2]. Linear trends across obesity classes by sex and age groups were examined in regression models and percentage point change from 2013 to 2016 for each age category calculated. All analyses accounted for sample weights for non-response, age and sex-calibrated to the French population. Prevalence of obesity ranged from 14.2 to 15.2% and from 14 to 15.3% in women and men respectively from 2013 to 2016. Class 1 obesity category prevalence was the only one to increase significantly across survey years in both men and women (p for linear trend = 0.04 and 0.01 in women and men respectively). The only significant increase for obesity was observed in the age group 18–29 y in both women and men (+ 2.71% and + 3.26% point increase respectively, equivalent to an approximate rise of 50% in women and 93% in men, p = 0.03 and 0.02 respectively). After adjustment for survey non-response and for age and sex distribution, the results show that class 1 obesity prevalence has significantly increased in both women and men from 2013 to 2016, and only in young adults in a representative sample of the French population aged 18–69 years old.

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