Abstract 18838: The Impacts of Burst Exercise Compared to Sustained Exercise on the Cardiometabolic Status and Exercise Behavior of Newly Diagnosed Type 2 Diabetic Patients
Introduction: Physical activity is an integral part of type 2 diabetes (NIDDM) rehabilitation. Historically, NIDDM rehabilitation has employed low intensity, sustained exercise. Recent studies have demonstrated cardiometabolic benefits of high intensity burst exercise in healthy volunteers. The impacts of burst exercise in NIDDM have yet to be assessed. This study compared the impacts of burst and sustained exercises on cardiometabolic factors including: BMI, exercise adherence, cardiopulmonary fitness, HbA1C and lipid profiles in newly diagnosed NIDDM. Hypothesis: High-intensity burst physical activity may yield greater cardiometabolic benefits than low intensity, sustained exercise. Methods: This was a single center, single blind randomized trial. 76 patients, within three months of diagnosis of NIDDM, were recruited. Patients were randomized to a control group prescribed 30 minutes of exercise five days a week at 65% of target heart rate or an intervention group prescribed ten minutes of exercise three times a day, five days a week at 85% of target heart rate. All patients underwent routine blood tests, stress tests and logged exercise duration and frequency in logbooks. Patients were excluded from the study if they had evidence for diabetic end organ damage or cardiovascular disease, or took medications which would impact the cardiometabolic parameters assessed in this study. Results: Of 225 patients screened, 76 patients were recruited for the study with an average age of 67; 70% were male. No significant differences in demographics were noted between groups. Patients prescribed the burst regimen exercised 27% more than the control (p<0.01). Burst exercise patients also showed a 2.3 fold greater improvement in HbA1c (p<0.01). The intervention group also improved more in their lipid profile, BMI and cardiopulmonary fitness (as measured by stress testing). Linear regression analysis revealed greater improvements in both HbA1C and BMI with burst exercise than with sustained exercise, for the same duration of exercise. Conclusions: The burst exercise regimen significantly improved the cardiometabolic and fitness status of newly diagnosed NIDDM. This regimen may represent a simple and effective way to improve diabetes rehabilitation.