Chronic Respiratory Disease, Comorbid Cardiovascular Disease, And Mortality In A Representative U.S. Cohort

Author(s):  
David M. Mannino ◽  
Kourtney J. Davis ◽  
Rachael L. DiSantostefano
Author(s):  
Chincholikar Sanjeev Vasantrao

Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus. Most people infected with the COVID-19 virus will experience mild to moderate respiratory illness and recover without requiring special treatment. It has been declared a pandemic by the World Health Organization which exhibited human-to-human transmissibility and spread rapidly across countries. Older people, and those with underlying medical problems like cardiovascular disease, diabetes, chronic respiratory disease, and cancer are more likely to develop serious illness. Climate, with temperature, humidity, Bacillus Calmette–Guérin (BCG) vaccination, immune status of persons, elderly people, uncontrolled co morbid conditions like heart diseases, diabetes mellitus, hypertension, kidney diseases seems to play an important role in spread and severity of corona virus infection. As reported from MOHFW website, the COVID-19 deaths are more in above 60 years of age with comorbidities cardiovascular disease, diabetes, chronic respiratory disease, and cancer.


2021 ◽  
pp. bmjspcare-2021-003107
Author(s):  
Lesley A. Henson ◽  
Emeka Chukwusa ◽  
Clarissa Ng Yin Ling ◽  
Shaheen A. Khan ◽  
Wei Gao

BackgroundThe presence of comorbidities in people with lung cancer is common. Despite this, large-scale contemporary reports describing patterns and trends in comorbidities are limited.Design and methodsPopulation-based patterns and trends analysis using Office for National Statistics Mortality Data. Our cohort included all adults who died from lung cancer (ICD-10 codes C33–C34) in England between 2001 and 2017. We describe decedents with 0, 1 or ≥2 comorbidities and explore changes overtime for the six most common comorbidities identified: chronic respiratory disease; diabetes; cardiovascular disease; dementia; cerebrovascular disease and chronic kidney disease. To determine future trends, the mean annual percentage change between 2001 and 2017 was calculated and projected forwards, while accounting for anticipated increases in lung cancer mortality.ResultsThere were 472 259 deaths from lung cancer (56.9% men; mean age 72.9 years, SD: 10.7). Overall, 19.0% of lung cancer decedents had 1 comorbidity at time of death and 8.8% had ≥2. The proportion of patients with comorbidities increased over time—between 2001 and 2017 decedents with 1 comorbidity increased 54.7%, while those with ≥2 increased 294.7%. The most common comorbidities were chronic respiratory disease and cardiovascular disease, contributing to 18.5% (95% CI: 18.0 to 18.9) and 11.4% (11.0 to 11.7) of deaths in 2017. Dementia and chronic kidney disease had the greatest increase in prevalence, increasing 311% and 289% respectively.ConclusionTo deliver high-quality outcomes for the growing proportion of lung cancer patients with comorbidities, oncology teams need to work across traditional boundaries of care. Novel areas for development include integration with dementia and chronic kidney disease services.


Author(s):  
Elham Ghazanchaei ◽  
Davoud Khorasani-Zavareh ◽  
Javad Aghazadeh-Attari ◽  
Iraj Mohebbi

Background: Patients with non-communicable diseases are vulnerable to disasters. This is a systematic review describing the impact of disasters on non-communicable diseases. Methods: A systematic review was conducted using PRISMA standards. Relevant articles published from 1997 to 2019 collected by searching the Scopus, PubMed, Science Direct, databases. We specifically examined reports describing NCDs and including the key words “non-communicable disease and Disasters”. NCDs included cardiovascular, respiratory, diabetes, cancer and mental health diseases. Results: Of the 663 studies identified, only 48 articles met all the eligibility criteria. Most studies have shown the impact of all natural disasters on non-communicable diseases (39.8% n=19). The largest study was the effect of earthquakes on non-communicable diseases (29.2% n=14). For the NCDs targeted by this research, most of the included studies were a combination of four diseases: cardiovascular disease, respiratory disease, diabetes and cancer (44% n=21). Followed by cardiovascular disease (14.6% n=7), chronic respiratory disease (12.5% n=6), diabetes and cancer (6.2% n=3) and mental health (12.5% n=6). Conclusion: The incidence of disasters affects the management of treatment and care for patients with NCDs. Specific measures include a multi-part approach to ensuring that patients with non-communicable diseases have access to life-saving services during and after disasters. The approach of the health system should be expanded from traditional approaches to disasters and requires comprehensive planning of health care by policy makers and health professionals to develop effective strategies to enable patients to access medical, therapeutic and diagnostic services in natural disasters.


2021 ◽  
Vol 5 (3) ◽  
Author(s):  
I Wayan Suryasa ◽  
María Rodríguez-Gámez ◽  
Tihnov Koldoris

The nurse has an important role caring for the patient infected with the coronavirus disease (COVID- 19). It is an infectious disease caused by the SARS-CoV-2 virus. The virus can spread from the mouth or nose of an infected person in small liquid particles when they cough, sneeze, speak, sing, or breathe. These particles range from larger respiratory droplets to smaller aerosols. It is important to practice respiratory etiquette, for example coughing into a flexed elbow, and to stay home and self-isolate until you recover if you feel unwell. Most people infected with the virus will experience mild to moderate respiratory illness and will recover without requiring special treatment. Older people and people with underlying medical conditions such as cardiovascular disease, diabetes, chronic respiratory disease, or cancer are more likely to develop serious illnesses. The goal of the research is to propose the best way to prevent and slow down transmission is to be well informed about the disease and how the virus spreads. Protect yourself and others from infection by staying at least 1 meter away from others, wearing a well-fitting mask, and washing your hands or using an alcohol-based rub frequently.


2018 ◽  
Vol 16 (3) ◽  
pp. 154-166 ◽  
Author(s):  
Karolina Lisy ◽  
Jared M. Campbell ◽  
Catalin Tufanaru ◽  
Sandeep Moola ◽  
Craig Lockwood

2020 ◽  
Author(s):  
Ebuka Miracle Anieto ◽  
Veronica Ebere Ogbodo ◽  
Ijeoma Blessing Nwadilibe ◽  
Omotoyosi Johnson Adu ◽  
Bouwien C.M. Smits-Engelsman ◽  
...  

Abstract BackgroundOlder individuals (over 60 years) with hypertension, diabetes, cardiovascular disease, chronic respiratory disease, and cancer are at the highest risk of contracting and dying from Coronavirus (COVID-19). Compromised immunity (both innate and adaptive) and increased inflammatory response (cytokine-storm syndrome) are predictors for high mortality among this population group. Exercise/physical activity seems to be a plausible way to decrease both the risk of transmission and mortality, and improve health outcomes among this population since there is no available treatment for COVID-19. The study will investigate the effectiveness of physical activity/exercise in improving the immune parameters and reducing the inflammatory biomarkers in proxy conditions that make individuals susceptible to COVID-19.MethodsThe Preferred Reporting Items for systematic reviews and Meta-Analyses Protocol (PRISMA-P) 2015 will guide this review. We will search ten databases (until August 2020) to include randomized control trials articles that explored the effectiveness of physical activity/exercise in improving immune parameters and reducing inflammatory biomarkers in proxy conditions (hypertension, diabetes, cardiovascular disease, chronic respiratory disease and cancer). Two review authors will independently screen citations (title and abstract), extract data (using standardized forms), assess the risk of bias (using Cochrane risks of bias) and quality of data (using GRADE). Homogenous studies will be analyzed using the fixed-effect model of meta-analysis, while a narrative synthesis will be conducted for heterogeneous studies.DiscussionThere are no specific physical activity/exercise parameters (frequency, intensity, type of exercise and time- FITT) for interventionists to use when developing high-quality RCT for individuals vulnerable to COVID-19. Therefore, it is important to review the literature to identify and highlight the exercise FITT parameters that increase the immune outcomes and reduce inflammatory biomarkers for proxy conditions that make individuals susceptible to COVID-19. It is also important to identify the specific exercise regimen suitable and beneficial for each proxy group.Systematic review registrationPROSPERO CRD42020196907


Sign in / Sign up

Export Citation Format

Share Document