scholarly journals Arterial Hypertension and Diabetes Mellitus as Risk Factors in the Evolution of Patients with COVID-19

2021 ◽  
Vol 6 (2) ◽  
pp. 22
Author(s):  
Carlos Miguel Campos Sanchez ◽  
Jose Carlos Garcia Roque ◽  
Liz Greit Garcia Rodriguez ◽  
Laura Adalys Guillen Leon ◽  
Juan Miguel Garcia Velazquez ◽  
...  
2019 ◽  
Vol 26 (17) ◽  
pp. 1843-1851 ◽  
Author(s):  
Anja Handschin ◽  
Stefanie Brighenti-Zogg ◽  
Jonas Mundwiler ◽  
Stéphanie Giezendanner ◽  
Claudia Gregoriano ◽  
...  

Aims Few data are available on cardiovascular risk stratification in primary care patients treated for arterial hypertension. This study aimed at evaluating the cardiovascular risk profile of hypertensive patients included into the Swiss Hypertension Cohort Study according to the 2013 European Society of Hypertension/European Society of Cardiology Guidelines. Methods The Swiss Hypertension Cohort Study is a prospective, observational study conducted by the Centre for Primary Health Care of the University of Basel from 2006 to 2013. Patients with a diagnosis of arterial hypertension (office blood pressure measurement ≥140/90 mmHg) were enrolled. Office blood pressure measurement, cardiovascular risk factors, subclinical organ damage, diabetes mellitus, and established cardiovascular and renal disease were recorded at baseline and at an annual interval during routine consultations by general practitioners in Switzerland. Results In total, 1003 patients were eligible for analysis (55.6% male, mean age: 64.0 ± 13.2 years). At baseline, 78.5% of patients presented with either more than three additional cardiovascular risk factors, diabetes mellitus or subclinical organ damage, while 44.4% of patients had a high or very high overall cardiovascular risk. Cardiovascular risk factors and information about diabetes mellitus, established cardiovascular disease and renal disease were recorded mostly completely, whereas substantial gaps were revealed regarding the assessment of subclinical organ damage. Conclusion The present findings demonstrate that the majority of primary care patients with arterial hypertension bear a substantial number of additional cardiovascular risk factors, subclinical and/or established organ damage. This emphasizes the need for continuous cardiovascular risk stratification and adequate treatment of arterial hypertension in Switzerland.


2013 ◽  
Vol 6 (2) ◽  
pp. 89-93
Author(s):  
Maya P. Danovska ◽  
Margarita L. Alexandrova ◽  
Irena I. Gencheva

Summary Individuals with hypertension and diabetes mellitus are at high risk of cerebrovascular and cardiovascular morbidity and mortality. Recent advances in the multifactorial pathophysiology of atherogenesis provide important information about the complex interrelations between traditional risk factors, inflammation and oxidative stress in mediating all stages of atherosclerosis. The objective of the study was to determine if some inflammatory and oxidative stress markers in patients with arterial hypertension and diabetes mellitus differ from those in healthy age-matched controls. Our results revealed a significant difference in blood pro/antioxidant activities in hypertensive diabetics and the controls. The investigation of inflammatory and oxidative stress markers along with traditional risk factors proves useful in complex assessment of vascular risk and primary prophylaxis of cerebrovascular and cardiovascular events.


2019 ◽  
Vol 27 (2) ◽  
pp. 172-180 ◽  
Author(s):  
Daria V. Seliverstova

Aim. Identification of risk factors (RF) for myocardial infarction (MI) among women with preserved menstrual function. Material and Methods. 121 Female patients under 55 years of age, who were hospitalized with MI in the cardiology departments of Ryazan in the period 2010-2016, were studied. All patients were divided into 2 groups. The first group included women with a regular menstrual cycle without menopausal symptoms (n=60, mean age 48.0±6.1 years). The second group consisted of postmenopausal women (n=61, mean age 49.8±4.3 years). Of a cohort of studied  women a group of women was isolated (n=18 from group 1 and n=15 from group 2) who, during hospitalization with MI in 2015-2016, filled in questionnaires on nutrition and physical activity. Results. In women of group 1 such risk factors as burdened heredity for cardiovascular diseases (58.3%, p=0.02) and smoking (46.7%, p=0.03) were more common than in women of group 2. Only women of group 1 took oral contraceptives before the onset of MI (15%, p=0.005). The most common RFs were: arterial hypertension (˃80% of patients in both groups; overweight and obesity (78.3% of women from group 1 and 83.6% from group 2); type 2 diabetes mellitus  (23.3% in group 1 and 24.6% in group 2). According to the results of the questionnaire on food habits, insufficient use of fruit and vegetables was detected among all patients of both groups. In analysis of the results of the International Physical Activity Questionnaire (IPAQ), 72.2% of patients in group 1 experienced insufficient physical activity, and 53.3% of patients in group 2 showed pronounced hypodynamia. Biochemical analysis of blood revealed increased average levels of total cholesterol, low-density lipoproteins and triglycerides, with high-density lipoproteins within the normal range in both groups. Conclusion. The most common risk factors for myocardial infarction in women with preserved menstrual function in comparison with postmenopausal women were: positive heredity for cardiovascular diseases, smoking and taking oral contraceptives. Besides, a wide spread of arterial hypertension, dyslipidemia and diabetes mellitus, overweight and obesity, low physical activity and lack of fruit and vegetables in the diet of women in both groups should be noted.


2018 ◽  
Vol 12 (4) ◽  
pp. 849
Author(s):  
Maria Evani Souza Borges ◽  
Jefferson De Sousa Melo ◽  
Luiza Chayanne Da Silva Soares ◽  
Adélia Dalva Da Silva Oliveira ◽  
Adriana Sávia De Souza Araújo ◽  
...  

RESUMOObjetivo: identificar os fatores de risco para a hipertensão arterial sistêmica e diabetes mellitus em vigilantes. Método: estudo quantitativo, descritivo, transversal, realizado com 23 vigilantes, por meio de um questionário analisado pelo software SPSS e apresentado em tabelas. Resultados: predominou os que praticam atividade física; não fumam; não consomem bebida alcóolica; consomem vegetais, frutas, legumes ou grãos; consomem frituras, salgados ou carnes gordas; têm antecedentes pessoais e familiares de hipertensão e diabetes, com maior ocorrência de hipertensão. A maioria obteve pressão arterial ótima e risco aumentado e muito aumentado para obesidade abdominal. Conclusão: apesar da atividade exercida ser considerada fator predisponente para a hipertensão arterial sistêmica e diabetes mellitus, os pesquisados demonstraram hábitos de vida saudáveis e níveis pressóricos dentro do padrão de normalidade. Descritores: Saúde Pública; Diabetes Mellitus; Hipertensão; Trabalho em Turnos; Fatores de Risco; Enfermagem.                                                                                                                    ABSTRACT Objective: to identify the risk factors for systemic arterial hypertension and diabetes mellitus in vigilantes. Method: quantitative, descriptive, cross - sectional study with 23 vigilantes, through a questionnaire analyzed by SPSS software and presented in tables. Results: predominantly those who practice physical activity; do not smoke; do not consume alcoholic beverage; consume vegetables, fruits, vegetables or grains; eat fried foods, salty foods or fatty meats; have a personal and family history of hypertension and diabetes, with a higher occurrence of hypertension. Most had optimal blood pressure and increased and greatly increased risk for abdominal obesity. Conclusion: although the activity was considered a predisposing factor for systemic arterial hypertension and diabetes mellitus, the subjects showed healthy habits and blood pressure levels within the normal range. Descritores: Public Health; Diabetes Mellitus; Hypertension; Shift Work; Risk Factors; Nursing. RESUMEN Objetivo: identificar los factores de riesgo para la hipertensión arterial sistémica y la diabetes mellitus en vigilantes. Método: estudio cuantitativo, descriptivo, transversal, realizado con 23 vigilantes, por medio de un cuestionario analizados por el software SPSS y presentados en tablas. Resultados: predominó los que practican actividad física; no fuman; no consumen bebida alcohólica; consumen vegetales, frutas, legumbres o granos; consumen frituras, salados o carnes gordas; tiene antecedentes personales y familiares de hipertensión y diabetes, con mayor ocurrencia de hipertensión. La mayoría obtuvo una presión arterial óptima y un riesgo aumentado y muy aumentado para la obesidad abdominal.  Conclusión: a pesar de la actividad ejercida como factor predisponente para la hipertensión arterial sistémica y diabetes mellitus, los encuestados demostraron hábitos de vida saludables y niveles de presión dentro del patrón de normalidad. Descritores: Salud Pública; Diabetes Mellitus; Hipertensión; Trabajo en Turnos; Factores de Riesgo; Enfermería.


Author(s):  
S. Kh. Mekhdiyev ◽  
I. I. Mustafaev ◽  
M. N. Mamedov

The presented study in Azerbaijan is carried out for the first time within State Programs on fight against a type 2 diabetes mellitus (DM2) and other noninfectious diseases.Aim.To define predictors of arterial hypertension (AH) in patients with DM2 in Azerbaijan population.Material and methods. In the single-step clinical-epidemiology cohort study were included 528 patients with DM2 at the age of 30-69 (30,5% — men and 69,5% — women) who answered questions using “ARIC” questioner to define AH and its risk factors.Results.The prevalence of AH in women (72,4%) was 2,6 times more than in men (27,6%) and the frequent occurrence of AH was at the age of 60-69 (respectively, 26,7±2,1% vs 9,6±2,9%, p<0,001). It was not determined remarkable differences between AH level and occupation status, alcohol consumption, low physical activity, feeding disorder of the patients, at the same time in patients with AH smoking frequency was about 2 times often than in others (respectively, 19,3±1,9% vs 10,6±3,0%, p<0,05). In parents of AH patients AH rates, in comparison with eutonics, were occurred like these: (respectively, in fathers 21,9±2,0% vs 12,5±3,2%, p<0,05; in mothers 42,2±2,4% vs 26,9±4,3%, p<0,01), in mothers DM2 (respectively, 33,7±2,3% vs 221 ±4,1 %, p<0,05), overweight and obesity were watched much more often (95,0±1,1% vs 88,5±3,1%, p<0,05), at the same time these patients were suffered from abdominal obesity (respectively, 96,5±0,9% vs 89,4±3,0%, p<0,01). The mean values of systolic and diastolic arterial pressure (respectively, 148,3±1,1 vs 119,8±1,3 Hg, p<0,001 and 85,9±0,5 vs 74,8±0,8 Hg, p<0,001) were often determined in patients with AH, and on the other hand in these patients were noted prevalence of anxious syndrome (respectively, 78,5±2,0% vs 72,1±4,4%, p<0,05) and depression (68,2±2,3% vs 62,5±4,7%, p>0,05). Regardless of AH level in all patients was noted stress (respectively, 99,8±0,2% vs 100,0±0,0%, p>0,05), which changed for the worse life quality of the patients with AH significantly (respectively, 1,0±2,2% vs 61,5±4,8%, p<0,05).Conclusion.For patients with DM2 in Azerbaijan cohort female sex, increasing of the age, body mass index, abdominal obesity and anxious conditions are significant risk factors for AH. Presence of AH in both parents and DM2 in mothers increase this risk significantly, which decrease life quality of these patients.


2019 ◽  
Vol 24 (4) ◽  
pp. 34-36
Author(s):  
Cătălin Cosmin Mutu ◽  
Larisa Georgiana Cerei

Abstract Ischemic stroke (IS) is the second frequent vascular disease after myocardial infarction, with different clinical and etiological aspects and various risk factors. Large vessel atherosclerotic disease is the most frequent IS causing pathology, followed by cerebral microangiopathy and cardioembolic events. Cervical arteries Doppler ultrasonography helps identifying the subtype of IS, and by revealing the vascular status of the patient, guides the therapeutic decision and secondary IS prevention. The aim of this paper is to present the results of an observational, retrospective, analytical study on a number of 174 patients with acute IS evaluated by Doppler carotid ultrasound in CVASIC Research Centre of Academic Emergency Hospital of Sibiu from January to December 2018. Materials and methods: All patients with IS admitted in our centre received a Doppler carotid ultrasound evaluation. We observed the degree of carotid stenosis, presence of atherosclerotic risk factors and their influence. Results: The mean age of patients was 71.3 years (36 to 92 years range). 16 (9.19%) patients presented occlusion of internal carotid artery (ICA) on the same side as stroke, 37 (21.26%) had severe carotid stenosis (>70%), 31 (17.81%) presented moderate stenosis (50-70%), the remaining patients had mild or no stenosis. 129 (74,13%) patients presented arterial hypertension, 51 (29.31%) patients had diabetes mellitus, 14 (8.04%) were smokers, 81 (46.56%) had dyslipidemia. Conclusions: A large number of patients had severe carotid stenosis and occlusion. The most common risk factor was arterial hypertension, followed by dyslipidemia and diabetes mellitus. Continuous medical education of population at risk regarding good nutrition principles and healthy lifestyle are needed to reduce the social costs of ischemic stroke.


VASA ◽  
2021 ◽  
Author(s):  
Anja Boc ◽  
Barbara Eržen ◽  
Rok Luciano Perme ◽  
Vinko Boc

Summary: Background: Disabling peripheral arterial disease (PAD) of femoropopliteal segment is usually treated with percutaneous balloon dilatation, and when this is not successful, stent is placed. Long-term patency of stent is often compromised due to in-stent restenosis (ISR). We aimed to identify factors associated with bailout stenting, and to recognise risk factors for ISR in procedures without paclitaxel application. Patients and methods: We analysed 592 consecutive successful femoropopliteal interventions performed in patients with either disabling intermittent claudication or chronic critical limb ischemia (CLI). In patients with stent implantation, clinical and ultrasound (US) examination were performed one year after the intervention to establish the presence of ISR, defined as >50% stenosis on US imaging. Results: Bailout stenting was required in 133 (22.5%) procedures. Patients with stent placement were younger (70±10 vs 72±11 years, p=0.007) and less often presented with CLI (29.3% vs 40.5%, p=0.019). They more often reported smoking (63.2% vs 49.2%, p=0.005), less often had diabetes mellitus (35.3% vs 47.5%, p=0.013) and arterial hypertension (82.0% vs 90.8%; p=0.004). Stenting was also dependent on lesion complexity (TASC II C>B>A; p<0.001). Subgroup analysis of 110 procedures with bare metal stent (BMS) placement performed in 107 patients revealed ISR in 46.4% of stents, in half of cases it was symptomatic. Neither clinical nor lesion characteristics proved to differ between the group of procedures with ISR and group of procedures without ISR. Conclusions: Factors associated with bailout stenting were age, diabetes mellitus, arterial hypertension, smoking, clinical picture of PAD and complexity of treated lesions. We did not find any risk factors influencing development of ISR in BMS.


Author(s):  
Benjamin Longo-Mbenza ◽  
Dieudonné Vangu Ngoma ◽  
Damien Nahimana ◽  
Dominique Mupepe Mayuku ◽  
Simon Mbungu Fuele ◽  
...  

Background The trend of hypertension and other risk factors of cardiovascular disease is changing because of epidemiological, demographic and nutritional transitions in sub-Saharan Africa. Objectives The aim of this study is to determine the prevalence and risk factors of arterial hypertension in the Kinshasa region, Democratic Republic of Congo (DRC). Design and methods Data were collected from random sample cross-sectional surveys of adult black Africans from Kinshasa, with the help of a structured questionnaire, physical examinations and blood samples, using the World Health Organisation (WHO) stepwise approach. Sex, age, place of residence (urban versus rural), psychosocial risk factors (socioeconomic status, stress), overweight status (BMI: 25–29.9 kg/m2), general obesity (BMI: ≥ 30 kg/m2), abdominal obesity (waist circumference: ≥ 94 cm) and diabetes mellitus were considered to be the potential risk factors for screen-detected hypertension. Results The weighted prevalences of hypertension, diabetes mellitus, overweight status, general obesity and abdominal obesity were 15.2, 140.2, 13.5, 4.8 and 7.5%, respectively. Blood pressure and the proportion of participants with hypertension increased with age and BMI group in the population, for both men and women. Age, rural residence, low socioeconomic status, high socioeconomic status, general obesity and abdominal obesity were the risk factors for hypertension. Women aged 55 years and above had higher levels of blood pressure and hypertension than men. Conclusion Absolute levels of hypertension, all types of obesity and diabetes mellitus are high risk factors in the army camps and semiurban extension cities; general obesity and abdominal obesity are the risk factors for detectable hypertension. Effective control of general obesity and abdominal obesity and psychosocial strategies that target both semirural and urban areas of the Kinshasa region have the potential to prevent much premature cardiovascular disease.


2020 ◽  
Vol 101 (6) ◽  
pp. 825-833
Author(s):  
I T Murkamilov ◽  
K A Aitbaev ◽  
V V Fomin ◽  
Zh A Murkamilova ◽  
F A Yusupov ◽  
...  

Chronic kidney disease and its complications are one of the leading causes of morbidity, disability and mortality in the world population, due to both the widespread prevalence of arterial hypertension, diabetes mellitus and coronary heart disease, and the increase in life expectancy. In the terminal stage of chronic kidney disease, mortality from cardiovascular events increases significantly. This review examines the most common risk factors for stroke in end-stage kidney disease. The role of arterial hypertension, diabetes mellitus, chronic heart failure is discussed, taking into account common risk factors, hyperactivation of the renin-angiotensin-aldosterone system, the development of oxidative stress, volume overload with an increase in the size of the left atrium and a subsequent increase in the risk of thrombosis and stroke in patients with end-stage kidney disease on programmed hemodialysis. In addition, data are presented in the study of the contribution of bone mineral disorders to the occurrence of cerebral complications in this category of patients. Timely diagnosis of cardiovascular diseases and secondary prevention of stroke, including adequate antihypertensive, hypoglycemic therapy and correction of heart failure with blockers of the renin-angiotensin-aldosterone system, as well as the elimination of bone mineral disorders are currently a very popular approach to improving the quality of life and increased survival in the discussed category of patients. Understanding the pathogenetic mechanism of stroke in patients with end-stage kidney disease on programmed hemodialysis, with the study of risk factors in the development of an acute cerebrovascular accident, will help to develop a strategy for their management.


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