Reconstruction in A Two-Person World May Be More About The Present Than The Past: Freud and The Wolf Man, an Illustration

2017 ◽  
Vol 65 (2) ◽  
pp. 305-316 ◽  
Author(s):  
Richard M. Gottlieb
Keyword(s):  
Clinical Utility ◽  
Emotional Involvement ◽  
Primal Scene ◽  
The Past ◽  
Clinical Relationship ◽  
Potential Clinical Utility ◽  
The Subject ◽  
The Relationship ◽  
Wolf Man ◽  
Broad Consensus

The psychoanalytic process of reconstruction has yet to be examined from the perspective of today’s two-person psychologies. Earlier writers on the subject have implicated the analyst and his emotional involvement as influences that may distort the valid recovery of memories, while others have written that the transference and the reconstructed past are interdependent. By contrast with both views, it is suggested here that the reconstructed product itself may reflect the transference-countertransference engagement of the dyad: in some instances, and to some extent in all instances, the scene or story of the presumed past will be a version of the current analytic relationship. In certain cases consideration of the conscious and unconscious emotional entanglements of the dyad will reveal that the reconstruction says more about the analytic present than about the past. Freud’s Wolf Man case provides a good illustration of this point. While a broad consensus exists that its famous primal scene reconstruction cannot be veridical, it has most often been dismissed as distorted by Freud’s theoretical commitments. A closer examination of the relationship between Freud and Pankejeff reveals that the reconstruction is an accurate rendering of warded-off aspects of the dyad’s way of being together. The potential clinical utility of adopting this perspective is that it encourages the analyst to reflect on his clinical reconstructions, interrogating them for clues to otherwise elusive aspects of the current clinical relationship.

Staring Down Death

Crisis ◽  
2016 ◽  
Vol 37 (3) ◽  
pp. 212-217 ◽  
Author(s):  
Thomas E. Joiner ◽  
Melanie A. Hom ◽  
Megan L. Rogers ◽  
Carol Chu ◽  
Ian H. Stanley ◽  
...  
Keyword(s):  
Suicide Risk ◽  
Clinical Utility ◽  
Blink Rate ◽  
Specific Task ◽  
Careful Planning ◽  
Eye Blink ◽  
Eye Blinks ◽  
Potential Clinical Utility ◽  
The Relationship

Abstract. Background: Lowered eye blink rate may be a clinically useful indicator of acute, imminent, and severe suicide risk. Diminished eye blink rates are often seen among individuals engaged in heightened concentration on a specific task that requires careful planning and attention. Indeed, overcoming one’s biological instinct for survival through suicide necessitates premeditation and concentration; thus, a diminished eye blink rate may signal imminent suicidality. Aims: This article aims to spur research and clinical inquiry into the role of eye blinks as an indicator of acute suicide risk. Method: Literature relevant to the potential connection between eye blink rate and suicidality was reviewed and synthesized. Results: Anecdotal, cognitive, neurological, and conceptual support for the relationship between decreased blink rate and suicide risk is outlined. Conclusion: Given that eye blinks are a highly observable behavior, the potential clinical utility of using eye blink rate as a marker of suicide risk is immense. Research is warranted to explore the association between eye blink rate and acute suicide risk.

scholarly journals Human TERT promoter mutations as a prognostic biomarker in glioma

2021 ◽  
Vol 147 (4) ◽  
pp. 1007-1017
Author(s):  
Branka Powter ◽  
Sarah A. Jeffreys ◽  
Heena Sareen ◽  
Adam Cooper ◽  
Daniel Brungs ◽  
...  
Keyword(s):  
Clinical Utility ◽  
Nucleotide Polymorphism ◽  
Liquid Biopsies ◽  
Single Nucleotide ◽  
Tert Promoter ◽  
Tert Promoter Mutations ◽  
Potential Clinical Utility ◽  
Promoter Mutations ◽  
The Relationship ◽  
Potential Use

AbstractThe TERT promoter (pTERT) mutations, C228T and C250T, play a significant role in malignant transformation by telomerase activation, oncogenesis and immortalisation of cells. C228T and C250T are emerging as important biomarkers in many cancers including glioblastoma multiforme (GBM), where the prevalence of these mutations is as high as 80%. Additionally, the rs2853669 single nucleotide polymorphism (SNP) may cooperate with these pTERT mutations in modulating progression and overall survival in GBM. Using liquid biopsies, pTERT mutations, C228T and C250T, and other clinically relevant biomarkers can be easily detected with high precision and sensitivity, facilitating longitudinal analysis throughout therapy and aid in cancer patient management.In this review, we explore the potential for pTERT mutation analysis, via liquid biopsy, for its potential use in personalised cancer therapy. We evaluate the relationship between pTERT mutations and other biomarkers as well as their potential clinical utility in early detection, prognostication, monitoring of cancer progress, with the main focus being on brain cancer.

scholarly journals Tocopherols and Tocotrienols—Bioactive Dietary Compounds; What Is Certain, What Is Doubt?

2021 ◽  
Vol 22 (12) ◽  
pp. 6222
Author(s):  
Kacper Szewczyk ◽  
Aleksandra Chojnacka ◽  
Magdalena Górnicka
Keyword(s):  
Vitamin E ◽  
Metabolic Disorders ◽  
Tissue Concentration ◽  
Biological Properties ◽  
Biological Role ◽  
Future Research ◽  
The Past ◽  
The Subject ◽  
The Relationship

Tocopherols and tocotrienols are natural compounds of plant origin, available in the nature. They are supplied in various amounts in a diet, mainly from vegetable oils, some oilseeds, and nuts. The main forms in the diet are α- and γ-tocopherol, due to the highest content in food products. Nevertheless, α-tocopherol is the main form of vitamin E with the highest tissue concentration. The α- forms of both tocopherols and tocotrienols are considered as the most metabolically active. Currently, research results indicate also a greater antioxidant potential of tocotrienols than tocopherols. Moreover, the biological role of vitamin E metabolites have received increasing interest. The aim of this review is to update the knowledge of tocopherol and tocotrienol bioactivity, with a particular focus on their bioavailability, distribution, and metabolism determinants in humans. Almost one hundred years after the start of research on α-tocopherol, its biological properties are still under investigation. For several decades, researchers’ interest in the biological importance of other forms of vitamin E has also been growing. Some of the functions, for instance the antioxidant functions of α- and γ-tocopherols, have been confirmed in humans, while others, such as the relationship with metabolic disorders, are still under investigation. Some studies, which analyzed the biological role and mechanisms of tocopherols and tocotrienols over the past few years described new and even unexpected cellular and molecular properties that will be the subject of future research.

New Agendas for Special Education Policy: What the National Reports Haven't Said

1987 ◽  
Vol 53 (4) ◽  
pp. 295-299 ◽  
Author(s):  
Marleen Pugach ◽  
Mara Sapon-Shevin
Keyword(s):  
Special Education ◽  
Education Policy ◽  
Educational Reform ◽  
Special Focus ◽  
Special Education Policy ◽  
The Past ◽  
The Subject ◽  
The Impact ◽  
The Relationship

The calls for educational reform that have dominated the professional and lay literature for the past few years have been decidedly silent in discussing the role of special education either as a contributor or a solution to the problems being raised. As an introduction to this “Special Focus” on the relationship between general educational reform and special education, this article summarizes some of the more prominent reports with regard to their treatment (and nontreatment) of special education. The impact of proposed reforms for the conceptualization and operation of special education is the subject of the five articles that follow.

I. The Augustan Historian

1974 ◽  
Vol 8 ◽  
pp. 5-7
Keyword(s):  
Nazi Germany ◽  
The Political ◽  
New Order ◽  
The Past ◽  
Ab Urbe Condita ◽  
The Future ◽  
The Subject ◽  
The Relationship

During the past forty years the dominant preoccupation of scholars writing on Livy has been the relationship between the historian and the emperor Augustus, and its effects on the Ab Urbe Condita. Tacitus’ testimony that the two were on friendly terms, and Suetonius’ revelation that Livy found time to encourage the historical studies of the future emperor Claudius, appeared to have ominous overtones to scholars writing against the political backcloth of Nazi Germany and Fascist Italy. Though the subject had not been wholly ignored previously, the success of the German cultural propaganda-machine stimulated a spate of approving or critical treatments. While some were hailing Livy as the historian whose work signalled and glorified the new order, others following a similar interpretation were markedly scathing.

scholarly journals Operant Matching as a Nash Equilibrium of an Intertemporal Game

2009 ◽  
Vol 21 (10) ◽  
pp. 2755-2773 ◽  
Author(s):  
Yonatan Loewenstein ◽  
Drazen Prelec ◽  
H. Sebastian Seung
Keyword(s):  
Nash Equilibrium ◽  
Matching Law ◽  
Single Subject ◽  
Multiple Selves ◽  
The Past ◽  
Aggregate Behavior ◽  
The Subject ◽  
Individual Choices ◽  
The Relationship ◽  
Mutual Defection

Over the past several decades, economists, psychologists, and neuroscientists have conducted experiments in which a subject, human or animal, repeatedly chooses between alternative actions and is rewarded based on choice history. While individual choices are unpredictable, aggregate behavior typically follows Herrnstein's matching law: the average reward per choice is equal for all chosen alternatives. In general, matching behavior does not maximize the overall reward delivered to the subject, and therefore matching appears inconsistent with the principle of utility maximization. Here we show that matching can be made consistent with maximization by regarding the choices of a single subject as being made by a sequence of multiple selves—one for each instant of time. If each self is blind to the state of the world and discounts future rewards completely, then the resulting game has at least one Nash equilibrium that satisfies both Herrnstein's matching law and the unpredictability of individual choices. This equilibrium is, in general, Pareto suboptimal, and can be understood as a mutual defection of the multiple selves in an intertemporal prisoner's dilemma. The mathematical assumptions about the multiple selves should not be interpreted literally as psychological assumptions. Human and animals do remember past choices and care about future rewards. However, they may be unable to comprehend or take into account the relationship between past and future. This can be made more explicit when a mechanism that converges on the equilibrium, such as reinforcement learning, is considered. Using specific examples, we show that there exist behaviors that satisfy the matching law but are not Nash equilibria. We expect that these behaviors will not be observed experimentally in animals and humans. If this is the case, the Nash equilibrium formulation can be regarded as a refinement of Herrnstein's matching law.

The Pathogenesis of Anaërobic Microbic Infections in the Major and Minor Psychoses, with Control Cases

1932 ◽  
Vol 78 (320) ◽  
pp. 12-95 ◽  
Author(s):  
W. M. Ford-Robertson
Keyword(s):  
Mental Disorders ◽  
Complex Problem ◽  
Chronic Infections ◽  
The Past ◽  
The Subject ◽  
Relationship Of ◽  
The Relationship

The subject of this thesis is the outcome of what might be termed a hereditary interest in the complex problem of the relationship of chronic infections to the psychoses and allied mental disorders. Circumstances enabled me, while still a student, to undertake very humbly the continuation of my father's researches in the Scottish Asylums' Laboratory at a point where his illness and death might have proved the closing of a long and arduous chapter. That this would have been so is, as far as I know, borne out by the fact that up to the present no work directly bearing on his later bacteriological studies has been published. The researches I have undertaken during the past six years have been an attempt to elucidate more clearly what exactly are the bacteriological factors at work, and, further, in what manner they attack the economy generally, and with what result. In my endeavour to verify and extend Ford-Robertson's views I have been singularly fortunate.

The Mechanical Requirements of the Royal National Lifeboat Institution

1941 ◽  
Vol 145 (1) ◽  
pp. 30-37 ◽  
Author(s):  
P. H. Johnson
Keyword(s):  
Rolling Resistance ◽  
Not Given ◽  
Internal Corrosion ◽  
The Past ◽  
Alternative Method ◽  
The Subject ◽  
Special Mention ◽  
General Aspects ◽  
The Relationship

After dealing briefly with the historical and general aspects of the subject, the author touches on the disposition of lifeboats round the coast and the factors which govern this distribution. Details of the boats themselves and their equipment are not given, but the paper concentrates on the difficulties involved, and the methods and equipment employed, in launching from the beach. Certain difficult beach conditions have been met by mounting the 11 tons of lifeboat and carriage on track units of the rigid girder type. Reference is made to the wheels employed in launching lighter boats in the past. Excessive rolling resistance made these wheels impracticable for soft beaches. The relationship between rolling resistance and the width and diameter of steel-tyred wheels is given, together with a description of the girdled wheels devised some forty years ago by Commander Gartside-Tipping, R.N. The development and construction of the girder track units now employed in place of wheels is fully dealt with. The method of launching a lifeboat by tractor is described, and shows how necessary are extreme reliability and watertightness in the tractor employed. The lifeboat “roadless” tractor is then described in detail and particulars given of the methods by which it is made waterproof. Special mention is made of gear for extracting the tractor from quicksand or mud pockets, and a résumé is given of the experience gained in this direction with tanks during the war of 1914–18. An alternative method to that adopted for waterproofing the tractor is referred to. A summary is provided of the submergence and other tests to which the tractor is subjected and of the special precautions which are taken in service to prevent trouble arising from internal corrosion due to condensation. The paper closes with the possible applications in other directions of the experience gained with the machinery described.

scholarly journals El acceso al pasado en una sociedad acelerada

2021 ◽  
Vol 24 ◽  
pp. 11-32
Author(s):  
Iker Samper Ayape
Keyword(s):  
The Internet ◽  
The Past ◽  
External Objects ◽  
The World ◽  
Current Context ◽  
The Subject ◽  
Siglo Xx ◽  
The Relationship ◽  
With Memory ◽  
Sobre Todo

Tras los acontecimientos bélicos que asolaron el mundo durante el siglo XX, en concreto, a partid de 1980, aumento el interés y el acercamiento teórico sobre el pasado y la memoria. Partiendo de ello, la cuestión a tratar en el presente trabajo es: qué características tiene nuestro presente y cómo esto determina algunas formas de acceso al pasado. Para luego preguntarnos sobre la relación que se establece con los memoriales, es decir, en qué medida el contexto o condiciones del sujeto mediatizan su relación con la memoria. Dado que la reflexión acerca de la memoria puede estar condicionada por las características propias de nuestro contexto: aceleración social. El acercamiento que puede tener un sujeto perteneciente a las generaciones más alejadas de lo acontecido en el siglo XX difiere mucho de la relación que pueden tener aquellos que vivieron el suceso o las consecuencias de una forma más inmediata. Por ello, debemos preguntarnos: ¿Hemos -sobre todo las generaciones más jóvenes- volcado la memoria y el conocimiento en objetos externos a los que recurrir y de esa manera no llevar el peso y poder adaptarnos al contexto actual? Estos objetos portadores de la memoria y conocimiento, como las imágenes, internet, o los memoriales, etc. ¿Están sólo bajo una lógica del consumo inmediato?, o ¿es el tipo de uso más potenciado? ¿Qué relación establecemos con los memoriales? Monumentos creados con el fin de recordar. After the warlike events that devastated the world during the 20th century, specifically, from 1980, interest and the theoretical approach on the past and memory increased. Starting from this, the question to be dealt with in the present work is: what characteristics does our present have and how this determines some forms of access to the past. To then ask ourselves about the relationship that is established with memorials, that is, to what extent the context or conditions of the subject mediate his relationship with memory. Since the reflection on memory can be conditioned by the characteristics of our context: social acceleration. The approach that a subject belonging to the generations furthest away from what happened in the twentieth century may have differs greatly from the relationship that those who experienced the event or the consequences can have in a more immediate way. For this reason, we must ask ourselves: Have we - especially the younger generations - turned memory and knowledge into external objects to turn to and thus not carry the weight and be able to adapt to the current context? These objects that carry memory and knowledge, such as images, the internet, or memorials, etc. Are they only under a logic of immediate consumption? Or is it the most enhanced type of use? What relationship do we establish with the memorials? Monuments created in order to remember.

Calvinism and Humanism: The First Generation

1975 ◽  
Vol 44 (2) ◽  
pp. 167-181 ◽  
Author(s):  
Robert D. Linder
Keyword(s):  
First Generation ◽  
Direct Relationship ◽  
John Calvin ◽  
Exact Nature ◽  
The Past ◽  
Reformed Church ◽  
The Reformation ◽  
The Subject ◽  
New Evidence ◽  
The Relationship

The nature of the relationship between the Renaissance and the Reformation has intrigued historians of both the past and the present. Recently a number of noted scholars have attempted to demonstrate the connection between the two movements with varying degrees of success. Historians seem to have marshalled an impressive and growing body of evidence to show the direct relationship between the advent of humanism and the coming of the Lutheran Reformation, even though the exact nature of this relationship has not yet been clarified in a definitive manner. But in the case of humanism and Calvinism no consensus has been reached concerning this problem; consequently, the situation is still in doubt. The purpose of this study is to enhance the historical understanding of the connection between humanism and Calvinism by a fresh analysis of the life and thought of three important first generation leaders of the Reformed church, namely, John Calvin, Theodore Beza and Pierre Viret. Moreover, new evidence on the subject from the career of Viret, the least known but nevertheless a very important member of this Calvinist trinity, will be presented to demonstrate more clearly the positive and direct link between humanism and Calvinism in the formative years of the Reformation.

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