Leiomyosarcoma of the Nasal Cavity and Paranasal Sinuses

1976 ◽  
Vol 85 (3) ◽  
pp. 399-403 ◽  
Author(s):  
Lloyd R. Dropkin ◽  
Chik Kwun Tang ◽  
John R. Williams
Keyword(s):  
Nasal Cavity ◽  
Paranasal Sinuses ◽  
Medical Literature ◽  
Recurrent Disease ◽  
Surgical Excision ◽  
High Rate ◽  
Term Survival ◽  
Complete Surgical Excision

A case of leiomyosarcoma of the nasal cavity and paranasal sinuses is presented along with a review of the medical literature. The clinicopathological aspects of this tumor are discussed. The mode of treatment is complete surgical excision with close follow-up due to its high rate of local recurrence. The long-term survival with recurrent disease in this case is unusual.

Neurilemmoma of the Nasal Cavity and Paranasal Sinuses

2021 ◽  
pp. 014556132110079
Author(s):  
Xindi He ◽  
Ying Wang
Keyword(s):  
Nasal Cavity ◽  
Paranasal Sinuses ◽  
Benign Tumor ◽  
Postoperative Radiotherapy ◽  
Surgical Excision ◽  
Complete Resection ◽  
Sinus Surgery ◽  
Complete Surgical Excision ◽  
The Mean

Objectives: Neurilemmoma in the nasal cavity and paranasal sinuses is very rare. The study aimed to improve the understanding of neurilemmoma in the nasal cavity and paranasal sinuses. Materials and Methods: The clinical data of 10 patients with neurilemmoma in the nasal cavity and paranasal sinuses treated from January 2014 to June 2019 in our hospital were retrospectively studied. Results: There were 6 females and 4 males patients in our study. The mean age was 49.5 years (range 37-77 years), and the most common clinical symptom was unilateral nasal obstruction. The site of tumor included the nasal cavity, maxillary sinus, ethmoid sinus, and sphenoid sinus. There were 2 cases with malignant neurilemmoma. Nine patients underwent functional endoscopic sinus surgery (FESS); however, 1 patient underwent FESS combined with the lateral rhinotomy for complete resection of the tumor. Two patients with malignant neurilemmoma received postoperative radiotherapy. The mean follow-up was 3.82 years (range 2-7 years). There were no incidences of tumor recurrence during the study period. Conclusions: Neurilemmoma in the nasal cavity and paranasal sinuses is a mainly benign tumor. Complete surgical excision by FESS is the only treatment option for neurilemmoma in the nasal cavity and paranasal sinuses; while malignant neurilemmoma needs postoperative radiotherapy.

Extramedullary Plasmacytoma of The Frontal Sinus: A Case Report

FACE ◽  
2021 ◽  
pp. 273250162110536
Author(s):  
Joshua Harrison ◽  
Samantha Marley ◽  
Shawhin Shahriari ◽  
Christian Bowers ◽  
Anil Shetty
Keyword(s):  
Frontal Sinus ◽  
Surgical Excision ◽  
Extramedullary Plasmacytoma ◽  
High Rate ◽  
Solitary Plasmacytoma ◽  
Case Presentation ◽  
Long Term Follow Up ◽  
History Of

We report a rare case of an extramedullary plasmacytoma (EMP) in the frontal sinus with an indolent clinical presentation. Although a history of trauma was absent, the initial diagnosis was a mucocele, based on the radiological findings. Upon surgical excision, the patient was found to have an EMP. EMP, a form of solitary plasmacytoma, has a significantly high rate of conversion to multiple myeloma. This mandates long-term follow-up, even after successful radiotherapy and/or resection. While radiation therapy is generally considered a first line treatment for EMP, surgical intervention may provide optimal treatment in complicated cases. This case presentation highlights the prognosis of patients diagnosed with EMP.

scholarly journals Cardiac Metastasis from Medullary Thyroid Cancers with Long-Term Survival under Vandetanib

2021 ◽  
pp. 1-6
Author(s):  
Camille Buffet ◽  
Sophie Leboulleux ◽  
Françoise Kraeber-Bodéré ◽  
Caroline Bodet-Milin ◽  
Laure Cabanes ◽  
...  
Keyword(s):  
Kinase Inhibitor ◽  
Surgical Excision ◽  
Cardiac Metastasis ◽  
Term Survival ◽  
Long Term Survival ◽  
Thyroid Cancers ◽  
Medullary Thyroid ◽  
Cardiac Metastases

<b><i>Background:</i></b> Cardiac metastases from thyroid cancers are uncommon with a poor prognosis. There is a lack of long-term follow-up studies. <b><i>Cases:</i></b> We report 2 cases of cardiac metastasis from medullary thyroid cancer (MTC). Both patients presented limited metastatic disease apart from a cardiac metastasis. The initial diagnosis was challenging and was facilitated by functional imaging with an immuno-PET-CT using an anti-CEA bispecific antibody and a <sup>68</sup>Ga-labeled peptide. Both patients were treated with the multitarget kinase inhibitor vandetanib with prolonged stability. The first patient was alive at the last follow-up, 14 years after the diagnosis of cardiac metastasis. The second patient required surgical excision of the cardiac mass because of disease progression under vandetanib. <b><i>Conclusion:</i></b> These cases illustrate long-term survival and effectiveness of clinical management of 2 patients who developed cardiac metastases from MTC, in the current era of personalized medicine with targeted therapy.

Efficacy of systemic chemotherapy (CT) for the patients (pts) with unresectable liver metastasis (LM) of colorectal cancer (CRC)

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 13567-13567
Author(s):  
K. Mera ◽  
A. Ohtsu ◽  
T. Doi ◽  
M. Muto ◽  
Y. Sano ◽  
...  
Keyword(s):  
Colorectal Adenocarcinoma ◽  
Recurrent Disease ◽  
Survival Rates ◽  
R0 Resection ◽  
Term Survival ◽  
Long Term Survival ◽  
Unresectable Liver Metastasis ◽  
Age Range

13567 Background: Surgical resection of colorectal LM is the only treatment which provides long-term survival for pts with advanced disease confined to the liver. However, most of LM are initially unresectable. The aim of this retrospective study was to evaluate the efficacy of systemic CT for the pts with initially unresectable LM from CRC. Methods: Subjects of this study were advanced CRC with unresectable LM treated by systemic CT at our institution between Aug ’92 and Dec ’03, and fulfilled the following criteria; Age ≤ 75, PS ≤ 2, histologically confirmed colorectal adenocarcinoma, no extrahepatic disease, no prior CT and no serious complication. Results: A total of 349 pts with metastatic CRC were managed by systemic CT between the period. Among these, there were 47 pts who met the recruitment criteria. Their characteristics were; male/female: 32/15, median age (range): 59 (34–75), PS 0/1/2: 33/12/2, primary tumor: colon/rectum: 26/21, sinchronous/metachronous: 26/21, number of LM: 4 ≥ / 5 ≤: 9/38. Regimens of CT were; 5FU/5FU+LV/CPT-11+5FU/CPT-11+5FU+LV/Others: 4/11/7/18/7. In all 47 pts, response rate was 53%, median survival time and 3-year survival rate were 14.6 month and 14.6%, respectively, at a median follow-up of 43.4 month. Seven of 47 (15%) could be secondarily resected after response to CT and all had R0 resection. Estimated 3-year survival rates in resected and non-resected pts were 57.1% and 0%, respectively. Prior CT before liver resection was CPT-11+5FU+LV (IFL)/CPT-11 alone: 6/1. Of the 7 resected pts, 2 pts are alive with no evidence of disease for 38 and 40 month after initiation of CT. Five of 7 pts relapsed (liver 3, liver and lung 2) and all treated with systemic CT for recurrence. Although recurrent disease is persisting, 2 of 5 are still alive for 34 and 48 month by continuing CT. Conclusions: Effective systemic CT allows some pts with unrsectable colorectal LM to be rescued by hepatic resection and provides a chance of long-term survival. No significant financial relationships to disclose.

Hemangiopericytoma of the Nasal Cavity: A Review of 15 Cases over a 40-Year Period

1992 ◽  
Vol 6 (6) ◽  
pp. 203-209 ◽  
Author(s):  
Kenneth V. Hughes ◽  
Michael C. Bard ◽  
Jean E. Lewis ◽  
Jan L. Kasperbauer ◽  
George W. Facer
Keyword(s):  
Local Recurrence ◽  
Nasal Cavity ◽  
Paranasal Sinuses ◽  
Clinical Course ◽  
Recurrence Rates ◽  
Long Term Follow Up ◽  
Vascular Origin ◽  
The Mean

Hemangiopericytomas are rare tumors of vascular origin most commonly found in the extremities or retroperitoneal area. When they originate from the nasal cavity and paranasal sinuses, they tend to be less aggressive and generally do not metastasize. The term “hemangiopericytoma-like lesion” has been coined for sinonasal hemangiopericytomas that display more benign histologic and growth characteristics than do those located elsewhere. Fifteen cases of hemangiopericytoma of the nasal cavity and paranasal sinuses were reviewed over the period 1951 to 1990; included are follow-up data on cases reported earlier from this institution. The clinical course, management, and outcome was evaluated and correlated with the histologic characteristics of the tumors. The recurrence rate in our series was 13.3%; the mean follow-up was 11 years. No patients died of their disease or had evidence of metastatic disease. This clinicopathologic review suggests that sinonasal hemangiopericytomas should not be classified as “hemangiopericytoma-like” lesions; rather, they should be expected to have significant local recurrence rates with low rates of distant metastasis and mortality. Long-term follow-up is essential as there can be local recurrence after many years.

Small cell neuroendocrine carcinoma of the nasal cavity and paranasal sinuses: a rare case

2012 ◽  
Vol 126 (12) ◽  
pp. 1284-1286 ◽  
Author(s):  
I P Tang ◽  
S Singh ◽  
G Krishnan ◽  
L M Looi
Keyword(s):  
Nasal Cavity ◽  
Neuroendocrine Carcinoma ◽  
Paranasal Sinuses ◽  
Rare Case ◽  
Surgical Excision ◽  
Small Cell ◽  
High Rate ◽  
Intracranial Extension ◽  
Small Cell Neuroendocrine Carcinoma ◽  
Rare Tumour

AbstractObjective:We report a rare case of small cell neuroendocrine carcinoma of the nasal cavity and paranasal sinuses with intracranial extension, and discuss the management of this rare tumour.Results:Small cell neuroendocrine carcinoma involving the nasal cavity and paranasal sinuses with intracranial extension may be treated successfully with surgery alone, without development of local recurrence.Conclusion:Small cell neuroendocrine carcinoma is a locally aggressive tumour with a high rate of recurrence. Early and aggressive surgical excision with or without radiotherapy or chemotherapy can improve a patient's outcome and prognosis. Regular follow up is needed to detect any local or distant recurrence.

scholarly journals Tricky nasal mass from meek polyp to intricate papilloma: A diagnostic dilemma

2021 ◽  
Vol 4 (3) ◽  
pp. 115-118
Author(s):  
Sphoorthi Basavannaiah
Keyword(s):  
Nasal Cavity ◽  
Paranasal Sinuses ◽  
Residual Disease ◽  
Inverted Papilloma ◽  
Antrochoanal Polyp ◽  
Diagnostic Dilemma ◽  
Nasal Mass ◽  
Epithelial Growth

Inverted papilloma is a benign epithelial growth arising from the underlying stroma of the nasal cavity and paranasal sinuses. The pathogenesis of this lesion uptil date remains unclear. The tumor is known for its local invasiveness, rapid recurrence and link with malignancy. The recurrence rate of this tumor is usually too high that represents residual disease in most of the cases. Hence, it is mandate that the patient keeps a proper follow up on long term concerns. Here is one such patient, whose nasal mass seemed Antrochoanal polyp clinically but ended up as Inverted papilloma histopathologically.

scholarly journals Massive angiomyofibroblastoma of the glans penis

2019 ◽  
Vol 12 (6) ◽  
pp. e229486 ◽  
Author(s):  
Sherif Monib ◽  
Mohamed Ibrahim
Keyword(s):  
Surgical Excision ◽  
Distant Recurrence ◽  
Glans Penis ◽  
Complete Surgical Excision ◽  
Long Term Follow Up ◽  
Rare Benign Tumour ◽  
Guide Lines ◽  
Male Genital

Male genital tract angiomyofibroblastoma (AMF) is a rare benign tumour, with a total of 34 cases reported in literature. We are presenting a case of AMF of the glans penis in a 68-year-old man who presented with a progressively increasing in size large lesion located on the tip of his penis. Following routine investigations, the lesion was surgically excised with no adjuvant treatment, the patient was followed-up for 5 years with no evidence of local, nodal or distant recurrence. As AMF of the glans penis is extremely rare, there is not enough literature to support management guide lines, but it appears that AMF responds very well to complete surgical excision; occasional cases of recurrence have been previously reported, so a long-term follow-up is advised.

scholarly journals Extragnathic Sinonasal Ameloblastoma: A Rare Benign Intranasal Tumor with Malignant Features

2013 ◽  
Vol 28 (1) ◽  
pp. 19-23
Author(s):  
Jonel Donn Leo S. Gloria
Keyword(s):  
Nasal Cavity ◽  
Paranasal Sinuses ◽  
Malignant Tumors ◽  
Lateral Displacement ◽  
Surgical Excision ◽  
University Hospital ◽  
Intracranial Extension ◽  
Complete Surgical Excision ◽  
Magnetic Resonance Imaging Mri ◽  
The Right

Objective:       To report a case of extragnathic sinonasal ameloblastoma and discuss its clinical features, approach to diagnosis, pathology, and management.   Methods: Study Design:             Case report Setting:                       Tertiary government university hospital Subject:                      One   Results:  A 40-year-old female consulted for a rapidly enlarging right intranasal mass of 4 months duration associated with recurrent profuse epistaxis and nasal obstruction.  Previous specimens of the mass were histopathologically interpreted as ameloblastoma versus craniopharyngioma.  Examination revealed a pink, fleshy, smooth right intranasal mass with associated nasomaxillary bulge and supero-lateral displacement of the right eye.  Computed tomography (CT) scan and magnetic resonance imaging (MRI) of the nasal cavity and paranasal sinuses demonstrated a soft-tissue density occupying the entire nasal cavity with erosion but no invasion of the maxillary sinus and no intracranial extension despite erosion of the skull base.  The mass was completely excised via lateral rhinotomy and the final histopathologic diagnosis was ameloblastoma.   Conclusion:    Extragnathic sinonasal ameloblastoma is a benign but locally aggressive variant of ameloblastoma involving the nasal cavity and/or paranasal sinuses often mimicking malignant tumors.  Diagnosis is primarily based on histopathology but radiologic and intraoperative findings help distinguish it from differentials.  Complete surgical excision remains the treatment of choice, and coupled with good follow up, may improve the prognosis of patients.   Keywords: sinonasal ameloblastoma, extragnathic, craniopharyngioma

scholarly journals Reoperation following Pancreaticoduodenectomy

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
J. R. Reddy ◽  
R. Saxena ◽  
R. K. Singh ◽  
B. Pottakkat ◽  
A. Prakash ◽  
...  
Keyword(s):  
Intestinal Obstruction ◽  
Retrospective Analysis ◽  
Anastomotic Leak ◽  
Adjuvant Radiotherapy ◽  
Recurrent Disease ◽  
Term Survival ◽  
Long Term Follow Up ◽  
Early Reoperation

Introduction. The literature on reoperation following pancreaticoduodenectomy is sparse and does not address all concerns.Aim. To analyze the incidence, causes, and outcome of patients undergoing reoperations following pancreaticoduodenectomy.Methods. Retrospective analysis of 520 consecutive patients undergoing pancreaticoduodenectomy from May 1989 to September 2010.Results. 96 patients (18.5%) were reoperated; 72 were early, 18 were late, and 6 underwent both early and late reoperations. Indications for early reoperation were post pancreatectomy hemorrhage in 53 (68%), pancreatico-enteric anastomotic leak in 10 (13%), hepaticojejunostomy leak in 3 (3.8%), duodenojejunostomy leak in 4 (5%), intestinal obstruction in 1 (1.2%) and miscellaneous causes in 7 (9%). Patients reoperated early did not fare poorly on long-term follow up. Indications for late reoperations were complications of index surgery (n= 12), recurrence of the primary disease (n= 8), complications of adjuvant radiotherapy (n= 3), and gastrointestinal bleed (n= 1). The median survival of 16 patients reoperated late without recurrent disease was 49 months.Conclusion. Early reoperations following pancreaticoduodenectomy, commonly for post pancreatectomy hemorrhage, carries a high mortality due to associated sepsis, but has no impact on long-term survival. Long-term complications related to pancreaticoduodenectomy and adjuvant radiotherapy can be managed successfully with good results.

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