scholarly journals Diagnostic Value of Urine Mercury Measurements

1977 ◽  
Vol 14 (1-6) ◽  
pp. 297-300 ◽  
Author(s):  
Andrew Taylor ◽  
Vincent Marks
Keyword(s):  
Heavy Metals ◽  
Case Reports ◽  
Diagnostic Value ◽  
Mercury Toxicity ◽  
Mercury Poisoning ◽  
Urine Mercury

A review of referrals to a regional heavy metals centre for possible mercury poisoning was made. Samples were received either from subjects who were well but were known to have some contact with mercury or from patients with an illness under investigation but undiagnosed. The problems associated with diagnosis of mercury toxicity in the absence of known exposure are illustrated by two case reports.

Elemental Mercury Exposure Among Children of Thermometer Plant Workers

PEDIATRICS ◽  
1987 ◽  
Vol 79 (6) ◽  
pp. 935-938
Author(s):  
Paul J. Hudson ◽  
Richard L. Vogt ◽  
Jack Brondum ◽  
Linden Witherell ◽  
Gary Myers ◽  
...  
Keyword(s):  
Mercury Level ◽  
Elemental Mercury ◽  
Mercury Exposure ◽  
Manufacturing Plant ◽  
Mercury Toxicity ◽  
Working Parents ◽  
Department Of Health ◽  
Mercury Thermometer ◽  
Urine Mercury ◽  
Pediatric Neurologist

Because evidence of mercury exposure was found among workers of a mercury thermometer-manufacturing plant in March 1984, the Vermont Department of Health studied the workers' children for both exposure to mercury and evidence of mercury toxicity. The median urine mercury level of 23 workers' children was 25 µg/L. This was significantly higher than the level (5 µg/L) among 39 children randomly selected from nonworkers' households in the same community (P < .001). Mercury-in-air levels measured in workers' homes were higher than those measured in control homes. A significant correlation was found between the urine mercury levels of the workers' children and the urine mercury levels of their working parents. No child had frank mercury toxicity. No evidence of neurologic toxicity among exposed children was discovered by a pediatric neurologist who examined these and unexposed children without knowledge of their exposure status. This is the first report demonstrating mercury exposure in children of mercury workers. Although toxic effects of mercury were not demonstrated at these levels of exposure, children of mercury workers are at risk for mercury exposure and potential mercury toxicity.

scholarly journals CAN WE IDENTIFY HIGH DIFFERENTIATED CANCER IN THYROID ULTRASOUND IMAGING?

2020 ◽  
Vol 23 (2) ◽  
pp. 42-47
Author(s):  
A. G. Butyrskii ◽  
V. Yu. Mikhaylichenko ◽  
V. V. Dubovenko ◽  
Yu. B. Shupta ◽  
I. B. Butyrskaia
Keyword(s):  
Thyroid Cancer ◽  
Ultrasound Imaging ◽  
Case Reports ◽  
Thyroid Neoplasms ◽  
Fine Needle Biopsy ◽  
Diagnostic Value ◽  
Papillary Cancer ◽  
Primary Diagnostics ◽  
Benign Nodules ◽  
Cancer Multiple

Primary diagnostics of thyroid neoplasms remains actual issue of modern endocrinology. Comprehensive clinical examination, ultrasound, and fine needle biopsy enable to make a conclusion about thyroid nodule properties but with a lot of mistakes, and take much time. Aims: assessment of diagnostic value of ultrasound criteria those may direct at papillary thyroid cancer. Materials and methods: one carried out observation multicenter retrospective continuous research among patients undergone for thyroid nodules surgery. It included adult patients (18-78) of both sexes. Patients’ case reports within 2013-2019 were sampled. Patients were shared into 2 groups according to final histological results. Results: the objects of research were 124 in-patients’ case reports. 32 of them were diagnosed thyroid cancer (24 - papillary, 8 – follicular), and 92 – benign nodules. Among searched criteria all (except hypoechogenicity) evidently differed between benign nodules and papillary cancer. In comparison criterion «absence of thin halo» reached the upper border of evidence of suspicion for papillary cancer. Multiple comparison indicated statistical difference between benign nodules (p<0,001) and follicular cancer (p<0,05). 2 of 24 papillary cancer patients (9%) in ultrasound did not demonstrate any criterion; all after this were arranged to benign nodules. 21 of 24 patients (88%) with 2 and more positive criteria were assessed correctly, but 51 of 92 benign nodules (56%) in ultrasound were assessed as papillary cancer. Conclusions: ultrasound imaging accuracy in thyroid papillary cancer is approximately equal in presence of 2 to 4 criteria; maximum accuracy (74%) is reached in presence of 3 criteria. In presence of 1 or 5 criteria is significantly lower: in 1 criterion due to low specificity, in 5 criteria – due to rarity of simultaneous combination. Follicular cancer can’t be identified in ultrasound imaging.

scholarly journals Differentiation between acute macular neuroretinopathy and paracentral acute middle maculopathy in elderly persons: two case reports

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Qin Zhang ◽  
Xiuhong Qin ◽  
Ling Xu
Keyword(s):  
Diabetes Mellitus ◽  
Optical Coherence Tomography ◽  
Case Reports ◽  
Young Patients ◽  
Diagnostic Value ◽  
Fundus Photography ◽  
Elderly Persons ◽  
Optical Coherence ◽  
Blurred Vision ◽  
Acute Macular Neuroretinopathy

Abstract Background We report one case of rare acute macular neuroretinopathy (AMN) in an elderly patient with hypertension and one case of common paracentral acute middle maculopathy (PAMM) in a patient with diabetes mellitus to illustrate the difference between the two diseases. Case presentation This report describes two cases, one involving AMN and the other PAMM. The first patient was a 70-year-old man complaining of blurred vision for 3 days. He was examined with fundus photography, optical coherence tomography angiography (OCTA) and optical coherence tomography (OCT); a diagnosis of AMN was established. The second patient was a 50-year-old woman who complained of decreased vision during the past month. She had had diabetes mellitus for 6 years. From the ophthalmic imaging examination, the patient was diagnosed with PAMM and non-proliferative diabetic retinopathy (NPDR). Both patients were treated with drugs for improving microcirculation and neurotrophic drugs; however, there was no significant improvement in visual acuity. Conclusions AMN is more common in young patients and is rarely observed in elderly patients with systemic diseases. The OCTA examination has an auxiliary diagnostic value for deep retinal capillary network ischaemia. Meanwhile, OCT examination has important imaging value in differentiating AMN from PAMM and can help avoid missed diagnoses.

scholarly journals The Study of Diagnostic Value of Bipolarity Index for Bipolar Disorder in China: Meta-analysis of Sensitivity and Specificity

2020 ◽  
Author(s):  
Fengli Sun ◽  
Zhu Jianfeng ◽  
Tao Hejian ◽  
Jin Weidong
Keyword(s):  
Bipolar Disorder ◽  
Predictive Value ◽  
Case Reports ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Diagnostic Value ◽  
Psychiatric Clinic ◽  
Significant Heterogeneity ◽  
Study Results

Abstract BackgroundThe diagnosis of bipolar disorder is still one of the key problems in psychiatric clinic. Although DSM-5 has made some important changes, it has not completely changed the missed diagnosis and misdiagnosis of bipolar disorder.It was very important that diagnostic scale was used in clinic.But the study results of assist diagnostic scale for bipolar disorder should been concluded and analyzed.Bipolarity index was one of assist diagnostic scale,which should be analyzed comprehensively.MethodsWe searched CBM, CNKI , WANFANG and CSSCI in Chinese to find literature from Julyr 31 2004 to July 31 2020 related to Bipolarity Index in diagnosis for bipolar disorder ,among which results such as comments, letters, reviews and case reports were excluded. The rate of sensitivity,specificity,accuracy,positive predictive value and negative predictive value in diagnosis was synthesized and discussed.ResultsA total of 1237 subjects were included in 5 studies. Random effect model is used to account for the data by Revman 5.2. The results showed that the sensitivity of BI in diagnostic was 0.93 (95% CI: 0.93–1.00), the specificity was 85% (95% CI: 0.69–0.96). the positive predict value was 74% (95% CI: 0.53–0.91).the negative predict value was 95% (95% CI: 0.81–1.00).and accuracy was 86% (95% CI: 0.77–0.93). Significant heterogeneity was detected across studies regarding these incidence estimates. ConclusionThe idea diagnostic value of BI was found. although the significant heterogeneity detected in studies.We must interpret the results with caution and also put attention to this result,which include comparison to other diagnostic scale,perfecting sue of BI in clinical psychiatry.

Environmental Pollution of Estuaries — A Problem of Hazards

1978 ◽  
Vol 5 (3) ◽  
pp. 205-211 ◽  
Author(s):  
C. L. So
Keyword(s):  
Heavy Metals ◽  
Environmental Monitoring ◽  
Environmental Pollution ◽  
Spatial Variations ◽  
Estuarine Environment ◽  
Mercury Poisoning ◽  
Long Run

The problem of environmental pollution of estuaries is viewed in the wider perspective, including the role of mixing, as a process common to estuaries and other systems and regulated by spatial variations. Increasing mobilization of heavy-metals and other pollutants to the estuarine environment, imparting hazards to Man in the long run, is a cause for concern and provides the reasons and bases for environmental monitoring. Already total lessons have been learnt from catastrophic outbreaks of mercury poisoning in Japan.

scholarly journals The Poisoning of Marinogammarus Marinus by Cupric Sulphate and Mercuric Chloride

1949 ◽  
Vol 26 (2) ◽  
pp. 113-124
Author(s):  
W. RUSSELL HUNTER
Keyword(s):  
Heavy Metals ◽  
Mercuric Chloride ◽  
Metabolic Process ◽  
Optimum Conditions ◽  
Mercury Poisoning ◽  
Low Concentrations ◽  
Marine Amphipod ◽  
Cupric Sulphate ◽  
Effect Of Copper ◽  
Copper Poisoning

The toxicity, under various conditions, of cupric sulphate and mercuric chloride to the marine amphipod, Marinogammarus marinus, has been studied. With optimum conditions copper is virtually non-toxic over the range of concentrations studied (e.g. becoming effective as a poison on decrease in salinity or oxygen tension). The toxic action of mercury is not greatly affected by changed conditions. At very low concentrations, copper has a pronounced effect on animals undergoing mercury poisoning. Subtoxic traces of mercury have no effect on the course of copper poisoning. It is suggested that in M. marinus, mercury acts directly by poisoning of the protoplasm while the effect of copper is indirect, involving the upset of some metabolic process. The relation of this work to other studies of the action of heavy metals is briefly discussed.

scholarly journals Assessment of Concentrations of Heavy Metals in Postmyocardial Infarction Patients and Patients Free from Cardiovascular Event

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Grzegorz Józef Nowicki ◽  
Barbara Ślusarska ◽  
Andrzej Prystupa ◽  
Eliza Blicharska ◽  
Agnieszka Adamczuk ◽  
...  
Keyword(s):  
Heavy Metals ◽  
Risk Factor ◽  
Environmental Exposure ◽  
Cardiovascular Event ◽  
Inductively Coupled Plasma ◽  
Area Under The Curve ◽  
Developed Countries ◽  
Diagnostic Value ◽  
Control Group ◽  
Postmyocardial Infarction

Cardiovascular diseases (CVDs) constitute the first cause of death among the population of developing and developed countries. Atherosclerosis, which is a disorder with multifactorial etiopathogenesis, underlies most CVDs. The available literature includes ample research studies on the influence of classic cardiovascular (CV) risk factors. However, environmental exposure to heavy metals, among other substances, is still an unappreciated risk factor of CVDs. This study aimed to assess the concentration of some heavy metals (copper (Cu), zinc (Zn), manganese (Mn), cobalt (Co), and iron (Fe)) in the blood serum of postmyocardial infarction (post-MI) patients and patients free from myocardial infarction (MI) as well as estimate the relationship between the occurrence of MI and increased concentration of heavy metals. The concentration of heavy metals (Cu, Zn, Mn, Co, and Fe) was assessed using the inductively coupled plasma mass spectrometry technique in a group of 146 respondents divided into two groups: post-MI group (study group (SG), n = 74) and group without cardiovascular event (CVE) having a low CV risk (control group (CG), n = 72). The concentration of the analyzed heavy metals was higher in SG. All the heavy metals showed a significant diagnostic value p < 0.001 . The highest value of area under the curve (AUC) was observed for manganese (Mn) (0.955; 95% confidence interval (CI) = 0.922–0.988), while the lowest value was found for zinc (Zn) (0.691; 95% CI = 0.599–0.782). In one-dimensional models, high concentrations of each of the analyzed heavy metals significantly increased the chances of having MI from 7-fold (Cu) to 128-fold (Mn). All the models containing a particular metal showed a significant and high discrimination value for MI occurrence (AUC 0.72–0.92). Higher concentrations of Cu, Zn, Mn, Co, and Fe were found to considerably increase the chances of having MI. Considering the increasingly higher environmental exposure to heavy metals in recent times, their concentrations can be distinguished as a potential risk factor of CVDs.

scholarly journals Implications and Significance of Mercury in Rice

2020 ◽  
pp. 1-5
Author(s):  
James R. Palmieri ◽  
Beverly Rzigalinski ◽  
Brooke Benjamin ◽  
Erin Collins ◽  
Gurleen Kaur ◽  
...  
Keyword(s):  
Heavy Metals ◽  
Heavy Metal ◽  
Rice Plant ◽  
Agricultural Soils ◽  
The United States ◽  
Mercury Content ◽  
Mercury Toxicity ◽  
Toxic Heavy Metal ◽  
The Usa ◽  
Control Samples

Previous research on rice asserts certain heavy metals, like mercury, in the agricultural soils are incorporated into the rice plant. Mercury is considered to be the most toxic heavy metal. This study aims to investigate mercury levels in rice grown in the United States versus rice imported from Asia. In this study, 29 samples of rice were compared for mercury content (12 from Thailand, 6 from India, 6 from China, compared to 5 control samples from the USA). Samples ranged from 0.18 to 6.01 ng of element / g. Further research is needed to establish standards for mercury toxicity.

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