Risk Factors in Multiple Carcinomas of the Lip

1980 ◽  
Vol 88 (3) ◽  
pp. 248-251 ◽  
Author(s):  
Shan R. Baker
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
General Population ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Prolonged Exposure ◽  
Significant Risk ◽  
Facial Skin ◽  
Actinic Cheilitis ◽  
Serologic Reaction

Certain risk factors appear to separate subjects with repeated primary carcinomas of the lip from the general population of patients with carcinoma of the lip. Factors that were found statistically significant in increasing the chance of recurrent carcinoma of the lip include outdoor occupations requiring prolonged exposure to sunlight or the use of tobacco on a regular basis. Significant risk factors of a clinical nature include a positive serologic reaction for syphilis; the presence of leukoplakia, hyperkeratosis, or actinic cheilitis; or the presence of a basal cell or squamous cell carcinoma of the facial skin.

scholarly journals Risk factors for distant metastasis in locoregionally controlled oral squamous cell carcinoma: a retrospective study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Hirofumi Tomioka ◽  
Yuko Yamagata ◽  
Yu Oikawa ◽  
Toshimitsu Ohsako ◽  
Takuma Kugimoto ◽  
...  
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Distant Metastasis ◽  
Significant Risk ◽  
Distant Metastases ◽  
Cervical Lymph Node Metastasis ◽  
Extranodal Extension

AbstractThe control of distant metastasis in oral squamous cell carcinoma is an important determinant of improved prognosis. The study aimed to identify risk factors for distant metastasis in patients with locoregionally controlled oral carcinoma. We identified 982 patients with oral squamous cell carcinoma treated at our hospital between January 2008 and December 2017. After excluding patients with distant metastasis at initial treatment, patients with metastasis to the oral cavity, those receiving palliative treatment, and those lacking follow-up data, 941 patients were selected. Finally, among these 941 patients, 887 with locoregionally controlled oral squamous cell carcinoma were included in the study. Among the 887 patients, 36 had confirmed distant metastasis (4.1%), and the lung was the most common site (31/36 patients, 86.1%). Multivariate analysis showed that the incidence of primary intraosseous carcinoma of the mandible, cervical lymph node metastasis at levels IV and V, and the presence of pathological extranodal extension were significant risk factors for distant metastasis. When treating patients with oral squamous cell carcinoma who are positive for the aforementioned risk factors, the possibility of developing distant metastases must be accounted for, and aggressive treatment should be planned accordingly.

scholarly journals Characteristics, risk factors and histopathological types of bronchogenic carcinoma among cases presented to Chest Department, Al-Zahraa Hospital, Al-Azhar University

2018 ◽  
Vol 5 (4) ◽  
pp. 1281
Author(s):  
Omaima I. Abo-Elkheir ◽  
Manal R. Hafez
Keyword(s):  
Risk Factors ◽  
Lung Cancer ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Bronchogenic Carcinoma ◽  
Significant Risk ◽  
Occupational Exposures ◽  
Cement Dust ◽  
Female Ratio

Background: Recently, lung cancer representing 5-7% of all cancers in Egypt with unavailable accurate epidemiological data. This study aims to identify characteristics, risk factors and histopathological types of bronchogenic carcinoma among a group of Egyptian patients.Methods: A cross sectional study was conducted on 123 cases of histopathological confirmed bronchogenic carcinoma presented to chest diseases department, Al-Zahraa Hospital, Al-Azhar University, Egypt in the period from July 2013 to May 2017. Statistical analysis of patients’ database was done using SPSS version 17.Results: Male to female ratio was 3.2:1; the majority of cases presented in their fifth (55.3%) and sixth (29.3%) decades of life, and urban: rural residence ratio was 2.1:1. Smoking was the most significant risk factor among 93.5% of cases, among them 65.9% were current smokers, 13.0% were ex-smokers and 14.6% were passive smokers. Occupational exposure to cement dust were reported among 47.2% of cases, 16.3% were farmers, 13.0% were employees, 8.9% were house wives, 8.1% were shoe makers and 6.5% were drivers. COPD was reported among 54.5% of cases. The commonest histopathological types were squamous cell carcinoma (31.7%), adenocarcinoma (30.9%), and large cell carcinoma (26.0%). Adenocarcinoma was the predominant type among females (55.3%), passive smokers (31.6%) and non-smokers (15.8%).Conclusions: Small cell lung cancer and squamous cell carcinoma subtypes were predominant among males, active smokers and workers exposed to cement dust. Adenocarcinoma was the commonest type among females, passive smokers and non-smokers. Conduction of anti-smoking campaigns; reduction of environmental pollution with regulation of occupational exposures to cement dust are recommended.

Rediscussing the Role of Traditional Risk Factors in Young Adults With Oral Squamous Cell Carcinoma

2020 ◽  
Vol 40 (12) ◽  
pp. 6987-6995
Author(s):  
NORBERT NECKEL ◽  
MARCO MICHAEL ◽  
DANIEL TROELTZSCH ◽  
JONAS WÜSTER ◽  
STEFFEN KOERDT ◽  
...  
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Young Adults ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Traditional Risk Factors

scholarly journals Leiomyosarcoma of the Tracheostomy Site in a Patient with History of Laryngeal Squamous Cell Carcinoma

2021 ◽  
pp. 912-917
Author(s):  
Zainub Ajmal ◽  
Abdul Moiz Khan ◽  
Lezah McCarthy ◽  
Allison Lupinetti ◽  
Syed Mehdi
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
English Literature ◽  
Neck Region ◽  
Multiple Risk Factors ◽  
History Of ◽  
Rare Malignancy

Leiomyosarcoma (LMS) of the trachea is an extremely rare malignancy with only a few reported cases in English literature. As such the diagnosis can be frequently missed or delayed. We present a case of a 69-year-old male who underwent tracheostomy for airway obstruction secondary to glottic squamous cell carcinoma and treated definitely with radiation therapy. Subsequently, the patient developed LMS of the tracheostomy site. The case further details multiple risk factors that could contribute to development of LMS including radiation exposure, prior malignancy, and chronic inflammation. These risk factors have been well established for LMS in other sites but less so in the head and neck region, which is the subject of our discussion. We also review the current guidelines for head and neck as well as limb sarcomas and discussed role of surgery or radiation and their accompanying challenges in management of this rare malignancy.

scholarly journals A nomogram to predict lymph node metastasis risk for early esophageal squamous cell carcinoma

BMC Cancer ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xiaofeng Duan ◽  
Xiaobin Shang ◽  
Jie Yue ◽  
Zhao Ma ◽  
Chuangui Chen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Early Stage ◽  
Derivation Cohort ◽  
Node Metastasis

Abstract Background A nomogram was developed to predict lymph node metastasis (LNM) for patients with early-stage esophageal squamous cell carcinoma (ESCC). Methods We used the clinical data of ESCC patients with pathological T1 stage disease who underwent surgery from January 2011 to June 2018 to develop a nomogram model. Multivariable logistic regression was used to confirm the risk factors for variable selection. The risk of LNM was stratified based on the nomogram model. The nomogram was validated by an independent cohort which included early ESCC patients underwent esophagectomy between July 2018 and December 2019. Results Of the 223 patients, 36 (16.1%) patients had LNM. The following three variables were confirmed as LNM risk factors and were included in the nomogram model: tumor differentiation (odds ratio [OR] = 3.776, 95% confidence interval [CI] 1.515–9.360, p = 0.004), depth of tumor invasion (OR = 3.124, 95% CI 1.146–8.511, p = 0.026), and tumor size (OR = 2.420, 95% CI 1.070–5.473, p = 0.034). The C-index was 0.810 (95% CI 0.742–0.895) in the derivation cohort (223 patients) and 0.830 (95% CI 0.763–0.902) in the validation cohort (80 patients). Conclusions A validated nomogram can predict the risk of LNM via risk stratification. It could be used to assist in the decision-making process to determine which patients should undergo esophagectomy and for which patients with a low risk of LNM, curative endoscopic resection would be sufficient.

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