Injuries to the Shoulder in the Throwing Athlete

2000 ◽  
Vol 28 (2) ◽  
pp. 265-275 ◽  
Author(s):  
Keith Meister
Keyword(s):  
Sports Medicine ◽  
Surgical Techniques ◽  
Diagnostic Techniques ◽  
Manual Examination ◽  
Shoulder Kinematics ◽  
Surgical Treatments ◽  
Insight Into ◽  
Throwing Motion ◽  
Made In ◽  
Sophisticated Technology

Over the last decade, significant advances have been made in the study and understanding of shoulder mechanics. Much of this may be attributed to the use of more sophisticated technology to improve our ability to assess the shoulder in real-time athletics. As a consequence of these advances, our understanding of the pathophysiology of injury has also increased. Our manual examination skills have improved and our noninvasive diagnostic techniques have advanced greatly. New insight into forces at play during actions as complex as the throwing motion has allowed us to develop better protocols for the prevention and treatment of the most common injuries. Additionally, paralleling improvements in the understanding of shoulder kinematics and the pathophysiology of injury, advances in surgical techniques, particularly arthroscopy, have aided in the diagnosis of and the development of less invasive surgical treatments for injuries that do not respond to nonoperative measures. Undoubtedly, an up-to-date understanding of the developments in shoulder biomechanics, pathophysiology of injury, diagnostic techniques, and surgical management is necessary for the clinician who wishes to continue to apply proper skills in the sports medicine setting.

The Coronary Circulation

1993 ◽  
Vol 115 (4B) ◽  
pp. 558-561 ◽  
Author(s):  
Robert E. Mates
Keyword(s):  
Bypass Surgery ◽  
Coronary Circulation ◽  
Surgical Techniques ◽  
Diagnostic Techniques ◽  
Resonance Imaging ◽  
Complete Understanding ◽  
Geometric Information ◽  
Artery Disease ◽  
And Control ◽  
Made In

Dramatic advances have been made in the last two decades in the diagnosis and treatment of coronary artery disease. The development of open heart surgical techniques for bypassing occluded arteries made quantitative diagnostic techniques more important. Computer enhanced angiographic methods, together with measurements using tomography, ultrasound and magnetic resonance imaging have greatly improved the precision of the diagnosis. A more complete understanding of coronary mechanics and control has enabled physicians to better interpret the significance of geometric information and to supplement this information with functional assessment of stenosed arteries. Finally, traditional bypass surgery is now supplemented with closed-chest techniques such as balloon angioplasty. Biomedical engineers have been involved in all of these developments. This paper will review these developments and attempt to identify remaining questions.

scholarly journals Progress in Local Treatment of Breast Cancer: A Narrative Review

2020 ◽  
Vol 42 (06) ◽  
pp. 356-364
Author(s):  
Francisco Pimentel Cavalcante ◽  
Eduardo Camargo Millen ◽  
Felipe Pereira Zerwes ◽  
Guilherme Garcia Novita
Keyword(s):  
Breast Cancer ◽  
Molecular Subtype ◽  
Local Treatment ◽  
Surgical Techniques ◽  
Distant Metastases ◽  
Randomized Controlled Clinical Trials ◽  
Systemic Adjuvant Therapy ◽  
Surgical Treatments ◽  
Disease Free ◽  
Made In

AbstractThe present paper reports on the local treatment of breast cancer from a historical perspective. A search for articles written in English was made in the Medline and EMBASE databases, and 40 papers were selected. Over the past 10 years, various randomized, controlled clinical trials on the local treatment of breast cancer indicated that patients with the same molecular subtype may receive different individualized surgical treatments aimed at optimizing systemic adjuvant therapy. With a view to retaining the gains made in disease-free and overall survival, surgical techniques have advanced from radical surgery to conservative mastectomies, thus reducing sequelae, while adjuvant and neoadjuvant therapies have contributed toward controlling the disease, both distant metastases and local recurrence. Current studies evaluate whether future breast cancer therapy may even succeed in eliminating surgery to the breast and axilla altogether.

Will Love Tear Us Apart: Adapting the Lyrical to the Ludic

CounterText ◽  
2016 ◽  
Vol 2 (2) ◽  
pp. 217-235
Author(s):  
Gordon Calleja
Keyword(s):  
Design Process ◽  
Game Design ◽  
Digital Games ◽  
Design Decisions ◽  
The Core ◽  
Lyrical Poetry ◽  
Insight Into ◽  
Made In

This paper gives an insight into the design process of a game adaptation of Joy Division's Love Will Tear Us Apart (1980). It outlines the challenges faced in attempting to reconcile the diverging qualities of lyrical poetry and digital games. In so doing, the paper examines the design decisions made in every segment of the game with a particular focus on the tension between the core concerns of the lyrical work being adapted and established tenets of game design.

New insight into the molecular switch mechanism of human Rho family proteins: shifting a paradigm

2013 ◽  
Vol 394 (1) ◽  
pp. 89-95 ◽  
Author(s):  
Mamta Jaiswal ◽  
Eyad Kalawy Fansa ◽  
Radovan Dvorsky ◽  
Mohammad Reza Ahmadian
Keyword(s):  
Quantitative Analysis ◽  
Bound State ◽  
Molecular Switch ◽  
Nucleotide Exchange ◽  
Gtp Binding ◽  
Switch Mechanism ◽  
Rho Family ◽  
Rho Family Proteins ◽  
Insight Into ◽  
Made In

Abstract Major advances have been made in understanding the structure, function and regulation of the small GTP-binding proteins of the Rho family and their involvement in multiple cellular process and disorders. However, intrinsic nucleotide exchange and hydrolysis reactions, which are known to be fundamental to Rho family proteins, have been partially investigated in the case of RhoA, Rac1 and Cdc42, but for others not at all. Here we present a comprehensive and quantitative analysis of the molecular switch functions of 15 members of the Rho family that enabled us to propose an active GTP-bound state for the rather uncharacterized isoforms RhoD and Rif under equilibrium and quiescent conditions.

Formation, translocation and resolution of Holliday junctions during homologous genetic recombination

1995 ◽  
Vol 347 (1319) ◽  
pp. 21-25 ◽  
Keyword(s):  
Molecular Mechanisms ◽  
Genetic Recombination ◽  
Holliday Junctions ◽  
The Novel ◽  
E Coli ◽  
The Past ◽  
Endonucleolytic Cleavage ◽  
Insight Into ◽  
Made In

Over the past three or four years, great strides have been made in our understanding of the proteins involved in recombination and the mechanisms by which recombinant molecules are formed. This review summarizes our current understanding of the process by focusing on recent studies of proteins involved in the later steps of recombination in bacteria. In particular, biochemical investigation of the in vitro properties of the E. coli RuvA, RuvB and RuvC proteins have provided our first insight into the novel molecular mechanisms by which Holliday junctions are moved along DNA and then resolved by endonucleolytic cleavage.

Recent progress in the freeze-etching technique

1971 ◽  
Vol 261 (837) ◽  
pp. 121-131 ◽  
Keyword(s):  
High Vacuum ◽  
Molecular Size ◽  
Etching Technique ◽  
Structural Distortions ◽  
Shadow Casting ◽  
Structural Details ◽  
Freeze Etching ◽  
The One ◽  
Insight Into ◽  
Made In

The freeze-etching technique must be improved if structures at the molecular size level are to be seen. The limitations of the technique are discussed here together with the progress made in alleviating them. The vitrification of living specimens is limited by the fact that very high freezing rates are needed. The critical freezing rate can be lowered on the one hand by the introduction of antifreeze agents, on the other hand by the application of high hydrostatic pressure. The fracture process may cause structural distortions in the fracture face of the frozen specimen. The ‘double-replica’ method allows one to evaluate such artefacts and provides an insight into the way that membranes split. During etching there exists the danger of contaminating the fracture faces with condensable gases. Because of specimen temperatures below —110 °C, special care has to be taken in eliminating water vapour from the high vacuum. An improvement in coating freeze-etched specimens has resulted from the application of electron guns for evaporation of the highest melting-point metals. If heat transfer from gun to specimen is reduced to a minimum, Pt, Ir, Ta, W and C can be used for shadow casting. Best results are obtained with Pt-C and Ta-W . With the help of decoration effects Pt-C shadow castings give the most information about the fine structural details of the specimen.

scholarly journals “It’s Not Just a Simple Meal. It’s So Much More”: Interactions Between Meals on Wheels Clients and Drivers

2018 ◽  
Vol 39 (2) ◽  
pp. 151-158 ◽  
Author(s):  
Kali S. Thomas ◽  
Emily A. Gadbois ◽  
Renee R. Shield ◽  
Ucheoma Akobundu ◽  
Andrea M. Morris ◽  
...  
Keyword(s):  
The United States ◽  
Case Managers ◽  
Qualitative Research Study ◽  
Personal Benefit ◽  
Meals On Wheels ◽  
Clear Insight ◽  
Additional Support ◽  
Insight Into ◽  
Made In ◽  
Meal Delivery

Background and Objectives: Meals on Wheels (MOW) programs provide home-delivered meals to over 1.5 million older adults; yet, very little is known about the drivers who make meal deliveries possible. Specifically, we do not have clear insight into their interaction with clients or the benefits that they may receive through their service. The objective of this article is to describe the characteristics of MOW drivers, the interactions among drivers and clients, and the benefits of the program to both. Research Design and Method: This qualitative research study reports on interviews with 84 MOW staff (leadership, case managers/client assessors, volunteer coordinators) and drivers at six geographically and operationally distinct programs across the United States. Results: Qualitative analysis of the interviews with MOW staff and drivers revealed the following key themes: (a) clients have multiple vulnerabilities; (b) clients appear to derive social, as well as nutritional benefit from receiving meals; (c) drivers report they provide additional support to their clients beyond delivering the meal; (d) social bonds between drivers and clients were reported to strengthen over time; (e) drivers claim that they, too, derive validation and personal benefit through their meal delivery. Discussion and Implications: This research highlights the significant contributions that meal delivery drivers made in the lives of MOW clients beyond the actual meal itself. This research also spotlights the perceived benefits experienced by the drivers and points to the importance of conducting further research to determine the effects of meal delivery on client and drivers’ outcomes, more broadly.

scholarly journals Closing up onto our sun: solar imaging

2020 ◽  
Vol 240 ◽  
pp. 07011
Author(s):  
Kushagra Shrivastava ◽  
Keith Wen Kai Chia ◽  
Kang Jun Wong ◽  
Alfred Yong Liang Tan ◽  
Hwee Tiang Ning
Keyword(s):  
Solar Activity ◽  
The Sun ◽  
Research Needs ◽  
Large Numbers ◽  
Wide Range ◽  
Future Science ◽  
Insight Into ◽  
Term Data ◽  
Made In

Solar activity research provides insight into the Sun’s past, future (Science Daily, 2018). The solar activity includes observations of large numbers of intense sunspots, flares, and other phenomena; and demands a wide range of techniques and measurements on the observations. This research needs long term data collection before critical analyses can occur, to generate meaningful learning and knowledge. In this project, we will use solar imaging to make observations of solar activity, and take our baby steps to make contributions in citizen science. Observations will be made in 3 wavelengths to gain a more thorough analysis by looking at different perspectives of the Sun, namely H-Alpha, Calcium-K, and white light.

scholarly journals Complications and Pitfalls in Maxillofacial Trauma

2014 ◽  
Vol 48 (2) ◽  
pp. 91-97
Author(s):  
Vidya Rattan ◽  
Sachin Rai ◽  
Shikha Yadav
Keyword(s):  
Treatment Failure ◽  
Surgical Procedure ◽  
Treatment Plan ◽  
Surgical Techniques ◽  
Maxillofacial Trauma ◽  
Trauma Surgeon ◽  
Form And Function ◽  
Fixation Devices ◽  
And Function ◽  
Made In

ABSTRACT Complications and pitfalls are unavoidable sequel of any surgical procedure. Although advances have been made in surgical techniques and fixation devices, these are far from ideal. The aim of trauma surgeon is to restore the patient to pre-injury form and function, but it may not be possible in each and every case. Treatment failure and poor outcome in a case of severe maxillofacial trauma is not uncommon. This is mainly dependent upon the extent of injury, delay in management, improper diagnosis, wrong treatment plan, poor execution of a treatment plan, wrong choice of fixation devices, inexperience of the surgeon and inability to seek help from other specialists, etc. The objective of this article is to discuss and analyze common complications and pitfalls along with the various methods and modalities to prevent and manage it. How to cite this article Rattan V, Rai S, Yadav S. Complications and Pitfalls in Maxillofacial Trauma. J Postgrad Med Edu Res 2014;48(2):91-97.

scholarly journals Korok és Kórok kiállítás 2019-2020

2021 ◽  
Vol 11 (22) ◽  
pp. 305-315
Author(s):  
Krisztina Scheffer ◽  
Enikő Szvák ◽  
Hedvig Győry
Keyword(s):  
Natural History ◽  
Educational Program ◽  
Art Museum ◽  
Additional Material ◽  
History Museum ◽  
Museum Visitors ◽  
Know How ◽  
Hungarian Natural History Museum ◽  
Insight Into ◽  
Made In

The HNM Semmelweis Museum of Medical History's exhibition „Diseases for the Ages, What the Deceased Tell Us”, is displaying the anthropological collection of the Museum which never was presented earlier, and the mummy-research made in the framework of the Nephthys Project, with some additional material from the Hungarian Natural History Museum and the Hopp Ferenc Asian Art Museum. Visitors can learn about the appearance of known and little-known diseases visible on archaeological human remains and gain insight into the know-how and the results of the mummy research. The exhibition is accompanied by a museum educational program and a series of lectures.

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