Retinal findings similar to retinopathy of prematurity in a term-infant with congenital cytomegalovirus infection

2021 ◽  
pp. 112067212110393
Author(s):  
Zuhal Ozen Tunay ◽  
Turan Derme ◽  
Damla Erginturk Acar ◽  
Esra Beser
Keyword(s):  
Retinopathy Of Prematurity ◽  
Retinal Vasculitis ◽  
Term Infant ◽  
Common Finding ◽  
Cmv Infection ◽  
Congenital Cytomegalovirus ◽  
Born Infant ◽  
Inflammatory Processes ◽  
History Of ◽  
The Relationship

Purpose: To present a term-born infant with congenital cytomegalovirus (C-CMV) infection with an atypical retinal finding mimicking retinopathy of prematurity (ROP). Case description: A term-born infant was referred to our clinic due to a C-CMV infection. Fundoscopic examination of both eyes revealed a demarcation line at zone II level and peripheral avascular retina along the temporal retina. There was no chorioretinitis, no vitritis, and no retinal vasculitis. There was no history of oxygen supplementation. The demarcation lines in both eyes regressed spontaneously within 3 weeks without any sequelae. Conclusions: It has been known for many years that C-CMV infection may affect the eye, and chorioretinitis is the most common finding. In this case report, we presented an atypical ROP-like retinal finding in an infant with C-CMV infection. We think that the development of retinal vascularization may be affected by C-CMV infection. We hope that this finding may provide a clue for future investigations to understand the relationship between the pathogenesis of ROP and infection-induced inflammatory processes in prenatal and perinatal life.

scholarly journals Plasma C-C Chemokine Concentrations in Intermediate Age-Related Macular Degeneration

2021 ◽  
Vol 8 ◽  
Author(s):  
Alan G. Palestine ◽  
Brandie D. Wagner ◽  
Jennifer L. Patnaik ◽  
Rebecca Baldermann ◽  
Marc T. Mathias ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Plasma Concentrations ◽  
Age Related Macular Degeneration ◽  
Disease Development ◽  
Cutoff Value ◽  
Multiplex Assays ◽  
Age Related ◽  
Inflammatory Processes ◽  
History Of ◽  
The Relationship

Purpose: To determine the relationship between plasma concentrations of the C-C chemokines CCL2, CCL3, CCL4, and CCL5 and intermediate age-related macular degeneration (iAMD) patients compared with control inidividuals to further define the inflammatory pathways associated with age-related macular degeneration.Methods: The concentrations of CCL2, CCL3, CCL4, and CCL5 were measured using multiplex assays in plasma collected from 210 patients with iAMD and 102 control individuals with no macular degeneration as defined by multi-modal imaging. Non-inflammatory data included in the analysis were: age, sex, family history of AMD, history of smoking, body mass index, presence of reticular pseudo-drusen and cardiovascular disease. Median concentrations as well as a cutoff value for each chemokine were compared between the two groups.Results: The median concentrations of CCL2 and CCL4 did not differ between control and iAMD groups, however, CCL2 was elevated in iAMD when a cutoff comparison was used (p < 0.05). Median CCL3 and CCL5 concentrations were significantly decreased in the macular degeneration group compared with controls (p < 0.001) as well as when a cutoff value comparison was used. CCL3 and CCL5 were negatively correlated in cases and positively correlated in controls.Conclusions: Plasma CCL3 and CCL5 concentrations were significantly decreased and CCL2 concentrations were increased in patients with iAMD compared with controls, suggesting a role for C-C chemokines in the systemic inflammatory processes associated with disease development.

The Etiology of Hysterical Seizures

1975 ◽  
Vol 20 (1) ◽  
pp. 67-73 ◽  
Author(s):  
K.F. Standage
Keyword(s):  
Brain Damage ◽  
Neurological Disease ◽  
Recent Literature ◽  
Previous History ◽  
Physical Illness ◽  
Common Finding ◽  
Eeg Abnormalities ◽  
History Of ◽  
The Relationship

Four patients have been described who were believed to be suffering from hysterical attacks. The recent literature on hysterical seizures has been examined and the four new patients were added to two other reported series to provide a profile of 25 cases. Preceding or accompanying physical illness was a common finding, and 32 percent of subjects had a previous history of neurological disease. The existence of a substrate of CNS damage is supported by the finding of EEG abnormalities in 40 percent of patients. In other ways the cases resembled classical descriptions of subjects liable to hysterical illness. The operation of either dissociative or conversion mechanisms during the attacks was difficult to demonstrate, and suggestion was sometimes the only factor found to account for the form of the symptoms. Further studies to examine the nature of the relationship between brain damage and hysterical disorders appear justified.

scholarly journals A case report of a pregnant woman with coronavirus disease 2019 (COVID-19) and her live-born infant

Biomedicine ◽  
2021 ◽  
Vol 40 (4) ◽  
pp. 551-553
Author(s):  
Altynai Zhumabekova ◽  
Tugolbai Tagaev ◽  
Vityala Yethindra ◽  
Shirin Zhumabaeva ◽  
Datka Ysabaeva ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Case Report ◽  
Pregnant Woman ◽  
Polymerase Chain Reaction Analysis ◽  
Term Infant ◽  
Chain Reaction ◽  
Global Pandemic ◽  
Born Infant ◽  
History Of ◽  
Polymerase Chain

In December 2019, an outbreak of coronavirus disease 2019 (COVID-19) occurred in Wuhan, China. The disease, which is now a global pandemic, is reportedly associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this study, we report a case of COVID-19 in a 31-year-old pregnant woman who showed symptoms that included fever, a four-day history of dry cough, and myalgia. Real-time reverse transcriptase-polymerase chain reaction analysis of naso- and oropharyngeal samples was positive for the SARS-CoV-2. A cesarean section was performed during the acute phase of COVID-19; the full-term infant was isolated from his mother and underwent formula feeding. He was healthy and negative for the SARS-CoV-2. This report describes the clinical features, diagnosis, and treatment of the mother’s illness and its effects on her live-born infant.

Clinical profile of symptomatic congenital cytomegalovirus infection: cases from a tertiary hospital in north India

2020 ◽  
Vol 50 (3) ◽  
pp. 282-284
Author(s):  
Deepanjan Bhattacharya ◽  
Inusha Panigrahi ◽  
Chakshu Chaudhry
Keyword(s):  
Intracranial Haemorrhage ◽  
Tertiary Hospital ◽  
North India ◽  
Common Finding ◽  
Cmv Infection ◽  
Chain Reaction ◽  
Congenital Cytomegalovirus Infection ◽  
Congenital Cytomegalovirus ◽  
The Mean ◽  
Polymerase Chain

We retrospectively analysed the records of nine infants with polymerase chain reaction proven congenital cytomegalovirus (CMV) infection, of which 66% were born preterm. Microcephaly was a universal finding, followed by hepatosplenomegaly in 89%, while chorioretinitis was seen in only 44% cases. The mean age at diagnosis was 3.5 months. Neuroimaging was abnormal in 78%, with ventriculomegaly being the most common finding followed by T2/FLAIR white matter abnormalities, periventricular cysts and intracranial haemorrhage.

scholarly journals A Seromolecular Study on the Prevalence of Cytomegalovirus in Pregnant Women Living in Golestan Province, Iran

2020 ◽  
Vol 21 (7) ◽  
Author(s):  
Elahe Lakzayi ◽  
Leila Fozouni ◽  
Hamidreza Pordeli
Keyword(s):  
Pregnant Women ◽  
Occupational Status ◽  
Molecular Techniques ◽  
Human Beings ◽  
Cmv Infection ◽  
Northern Iran ◽  
Study Results ◽  
History Of ◽  
Golestan Province ◽  
The Relationship

Background: Infection with cytomegalovirus (CMV) is highly frequent during pregnancy in human beings, which mostly results in preterm birth. Objectives: The current study aimed at comparing serological and molecular methods to determine the frequency of CMV infection in pregnant women admitted to hospitals in Golestan Province, Northern Iran. Methods: The study was conducted on 315 blood samples collected from pregnant women. After completion of the screening test questionnaire, CMV-IgG, CMV-IgM, and CMV-IgG avidity tests were performed to determine the seropositivity prevalence of CMV. Finally, after DNA extraction, the PCR technique was employed to detect the CMV genome in the samples. Results: Out of the studied women, 81.2% were positive for CMV-IgG and CMV-IgM, but only 8.2% had positive results in the molecular detection of CMV, out of which 61.9% had a history of abortion. In terms of the correlation between ethnicity and infection with CMV, 66.7% of positive samples belonged to Fars ethnic group. The relationship between ethnicity and occupational status in terms of CMV infection revealed that 85% of Fars and 29% of Turkmen housewives were positive for CMV. In terms of the relationship between ethnicity and age, 35% of pregnant women from Fars and 42% from Turkmen ethnic groups were over 30 years. Furthermore, the results showed that 71% of Fars and 42% of Turkmen pregnant women were infected with CMV during the 2nd trimester of pregnancy. Among all these variables, a significant relationship was observed only between the age of pregnant women and infection with CMV (P = 0.045). Conclusions: The current study results showed that despite the increasing frequency of CMV infection in pregnant women, seropositivity, and even higher titers of CMV-IgG have no predictive value for active CMV infection. Concerning the importance of rapid and definitive diagnosis of the disease before the emergence of manifestations, molecular techniques could be of great help as they are effective in the diagnosis of infection with smaller amounts of the pathogenic genome.

The relationship of the scleractinian corals to the rugose corals

Paleobiology ◽  
1980 ◽  
Vol 6 (02) ◽  
pp. 146-160 ◽  
Author(s):  
William A. Oliver
Keyword(s):  
Critical Points ◽  
Scleractinian Corals ◽  
Convincing Evidence ◽  
Early Triassic ◽  
Rugose Corals ◽  
History Of ◽  
The Subject ◽  
Relationship Of ◽  
The Relationship ◽  
Biologic Factors

The Mesozoic-Cenozoic coral Order Scleractinia has been suggested to have originated or evolved (1) by direct descent from the Paleozoic Order Rugosa or (2) by the development of a skeleton in members of one of the anemone groups that probably have existed throughout Phanerozoic time. In spite of much work on the subject, advocates of the direct descent hypothesis have failed to find convincing evidence of this relationship. Critical points are:(1) Rugosan septal insertion is serial; Scleractinian insertion is cyclic; no intermediate stages have been demonstrated. Apparent intermediates are Scleractinia having bilateral cyclic insertion or teratological Rugosa.(2) There is convincing evidence that the skeletons of many Rugosa were calcitic and none are known to be or to have been aragonitic. In contrast, the skeletons of all living Scleractinia are aragonitic and there is evidence that fossil Scleractinia were aragonitic also. The mineralogic difference is almost certainly due to intrinsic biologic factors.(3) No early Triassic corals of either group are known. This fact is not compelling (by itself) but is important in connection with points 1 and 2, because, given direct descent, both changes took place during this only stage in the history of the two groups in which there are no known corals.

Investigating the Relationship Between Self-Esteem and Stigma Among Young Adults With History of Suicide Attempts

Crisis ◽  
2016 ◽  
Vol 37 (4) ◽  
pp. 265-270 ◽  
Author(s):  
Meshan Lehmann ◽  
Matthew R. Hilimire ◽  
Lawrence H. Yang ◽  
Bruce G. Link ◽  
Jordan E. DeVylder
Keyword(s):  
Young Adults ◽  
Suicide Attempts ◽  
Self Esteem ◽  
High Risk Population ◽  
High Functioning ◽  
People With Mental Illness ◽  
History Of ◽  
The Individual ◽  
The Impact ◽  
The Relationship

Abstract. Background: Self-esteem is a major contributor to risk for repeated suicide attempts. Prior research has shown that awareness of stigma is associated with reduced self-esteem among people with mental illness. No prior studies have examined the association between self-esteem and stereotype awareness among individuals with past suicide attempts. Aims: To understand the relationship between stereotype awareness and self-esteem among young adults who have and have not attempted suicide. Method: Computerized surveys were administered to college students (N = 637). Linear regression analyses were used to test associations between self-esteem and stereotype awareness, attempt history, and their interaction. Results: There was a significant stereotype awareness by attempt interaction (β = –.74, p = .006) in the regression analysis. The interaction was explained by a stronger negative association between stereotype awareness and self-esteem among individuals with past suicide attempts (β = –.50, p = .013) compared with those without attempts (β = –.09, p = .037). Conclusion: Stigma is associated with lower self-esteem within this high-functioning sample of young adults with histories of suicide attempts. Alleviating the impact of stigma at the individual (clinical) or community (public health) levels may improve self-esteem among this high-risk population, which could potentially influence subsequent suicide risk.

Misreading Egypt

2018 ◽  
Author(s):  
Jesse Schotter
Keyword(s):  
New Media ◽  
Narrative Form ◽  
Experimental Film ◽  
Tower Of Babel ◽  
Avant Garde ◽  
Sergei Eisenstein ◽  
History Of ◽  
The One ◽  
The Relationship ◽  
Modern Technologies

The first chapter of Hieroglyphic Modernisms exposes the complex history of Western misconceptions of Egyptian writing from antiquity to the present. Hieroglyphs bridge the gap between modern technologies and the ancient past, looking forward to the rise of new media and backward to the dispersal of languages in the mythical moment of the Tower of Babel. The contradictory ways in which hieroglyphs were interpreted in the West come to shape the differing ways that modernist writers and filmmakers understood the relationship between writing, film, and other new media. On the one hand, poets like Ezra Pound and film theorists like Vachel Lindsay and Sergei Eisenstein use the visual languages of China and of Egypt as a more primal or direct alternative to written words. But Freud, Proust, and the later Eisenstein conversely emphasize the phonetic qualities of Egyptian writing, its similarity to alphabetical scripts. The chapter concludes by arguing that even avant-garde invocations of hieroglyphics depend on narrative form through an examination of Hollis Frampton’s experimental film Zorns Lemma.

Meat without Animals: Outcast Objects and the Improvement of London

2018 ◽  
Author(s):  
Ted Geier
Keyword(s):  
Animal Rights ◽  
Legal Reform ◽  
Meat Production ◽  
History Of ◽  
Relationship Of ◽  
The Relationship

Covers the long history of the Smithfield animal market and legal reform in London. Shows the relationship of civic improvement tropes, including animal rights, to animal erasure in the form of new foodstuffs from distant meat production sites. The reduction of lives to commodities also informed public abasement of the butchers.

A Note on the Publication History of John Polidori's The Vampyre

2020 ◽  
Vol 22 (3) ◽  
pp. 330-343
Author(s):  
Fabio Camilletti
Keyword(s):  
Textual Criticism ◽  
Active Role ◽  
Publication History ◽  
History Of ◽  
The Relationship ◽  
Opening Up

It is generally assumed that The Vampyre was published against John Polidori's will. This article brings evidence to support that he played, in fact, an active role in the publication of his tale, perhaps as a response to Frankenstein. In particular, by making use of the tools of textual criticism, it demonstrates how the ‘Extract of a Letter from Geneva’ accompanying The Vampyre in The New Monthly Magazine and in volume editions could not be written without having access to Polidori's Diary. Furthermore, it hypothesizes that the composition of The Vampyre, traditionally located in Geneva in the course of summer 1816, can be postdated to 1818, opening up new possibilities for reading the tale in the context of the relationship between Polidori, Byron, and the Shelleys.

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