scholarly journals A Seromolecular Study on the Prevalence of Cytomegalovirus in Pregnant Women Living in Golestan Province, Iran

2020 ◽  
Vol 21 (7) ◽  
Author(s):  
Elahe Lakzayi ◽  
Leila Fozouni ◽  
Hamidreza Pordeli

Background: Infection with cytomegalovirus (CMV) is highly frequent during pregnancy in human beings, which mostly results in preterm birth. Objectives: The current study aimed at comparing serological and molecular methods to determine the frequency of CMV infection in pregnant women admitted to hospitals in Golestan Province, Northern Iran. Methods: The study was conducted on 315 blood samples collected from pregnant women. After completion of the screening test questionnaire, CMV-IgG, CMV-IgM, and CMV-IgG avidity tests were performed to determine the seropositivity prevalence of CMV. Finally, after DNA extraction, the PCR technique was employed to detect the CMV genome in the samples. Results: Out of the studied women, 81.2% were positive for CMV-IgG and CMV-IgM, but only 8.2% had positive results in the molecular detection of CMV, out of which 61.9% had a history of abortion. In terms of the correlation between ethnicity and infection with CMV, 66.7% of positive samples belonged to Fars ethnic group. The relationship between ethnicity and occupational status in terms of CMV infection revealed that 85% of Fars and 29% of Turkmen housewives were positive for CMV. In terms of the relationship between ethnicity and age, 35% of pregnant women from Fars and 42% from Turkmen ethnic groups were over 30 years. Furthermore, the results showed that 71% of Fars and 42% of Turkmen pregnant women were infected with CMV during the 2nd trimester of pregnancy. Among all these variables, a significant relationship was observed only between the age of pregnant women and infection with CMV (P = 0.045). Conclusions: The current study results showed that despite the increasing frequency of CMV infection in pregnant women, seropositivity, and even higher titers of CMV-IgG have no predictive value for active CMV infection. Concerning the importance of rapid and definitive diagnosis of the disease before the emergence of manifestations, molecular techniques could be of great help as they are effective in the diagnosis of infection with smaller amounts of the pathogenic genome.

2010 ◽  
Vol 2010 ◽  
pp. 1-8 ◽  
Author(s):  
Vanessa L. Short ◽  
Jørgen S. Jensen ◽  
Deborah B. Nelson ◽  
Pamela J. Murray ◽  
Roberta B. Ness ◽  
...  

Objective. As the consequences ofMycoplasma genitaliumin pregnant women are unknown, we examined the relationship between prenatalM. genitaliuminfection and SAB.Methods. The presence ofM. genitaliumwas determined by PCR in urine from 82 women who subsequently experienced a SAB and 134 women who maintained their pregnancies past 22 weeks gestation. The relationships betweenM. genitaliumand subsequent SAB, demographic, current pregnancy, and reproductive health history characteristics were evaluated.Results. Compared to women withoutM. genitalium, women withM. genitaliumwere more likely to report nulliparity (41.7% versus 17.4%,P=.04), history of pelvic inflammatory disease (27.3% versus 8.8%,P=.08), priorC. trachomatisinfection (63.6% versus 36.9%,P=.11,) and problems getting pregnant (18.2% versus 4.4%,P=.10).M. genitaliumwas not associated with SAB (AOR 0.9, 95% CI 0.2–3.8).Conclusions. Pregnant women who test positive forM. genitaliumdo not have an increased risk of SAB but report a history of reproductive morbidities.


2019 ◽  
Vol 10 (2) ◽  
pp. 358
Author(s):  
Diah Andriani ◽  
Rusnoto Rusnoto

Latar Belakang: Preeklampsia/eklampsia merupakan salah satu penyebab utama morbiditas dan mortalitas perinatal di Indonesia. Sampai sekarang penyakit preeklamsia/eklamsia masih merupakan masalah kebidanan yang belum dapat erpecahkan secara tuntas. Preeklampsia merupakan penyakit yang angka kejadiannya di setiap negara berbeda-beda.Tujuan : Mengetahui hubungan paritas, riwayat kehamilan,dan asupan kalsium dengan kejadian pre eklampsia berat di UPT Puskesmas Jepang.Metode: Dalam penelitian ini yang menjadi populasi adalah semua ibu hamil yang melakukan ANC di Puskesmas Jepang Kecamatan Mejobo Kabupaten Kudus pada bulan Agustus 2017 sebanyak 30 ibu hamil.Sampel dalam penelitian ini adalah ibu hamil yang melakukan kunjungan ANC di Puskesmas Jepang Kecamatan Mejobo Kabupaten Kudus  pada bulan Agustus 2017 sebanyak 30 orang. Analisis data menggunakan analisis univariat dan bivariat. Hasil penelitian Mayoritas responden memiliki paritas multipara sebanyak 18 orang (60%), dan yang primipara sebanyak 12 orang (40%). Mayoritas responden memiliki riwayat tidak pernah pre eklampsia berat sebanyak 16 orang (53,3%) dan yang pernah pre eklampsia berat sebanyak 14 orang (46,7%). Mayoritas responden memiliki asupan kalsium cukup sebanyak 18 orang (60%) dan yang asupan kalsium tidak cukup sebanyak 12 orang (40%). Mayoritas responden tidak pre eklampsia berat sebanyak 18 orang (60%) dan yang pre eklampsia berat sebanyak 12 orang (40%). Ada  hubungan paritas dengan kejadian pre eklampsia berat di upt puskesmas jepang (p value = 0,001). Ada  hubungan riwayat kehamilan dengan kejadian pre eklampsia berat di upt puskesmas jepang (p value = 0,001). Ada  hubungan asupan kalsium dengan kejadian pre eklampsia berat di upt puskesmas jepang (p value = 0,009). Berdasarkan analisis regresi faktor yang paling berpengaruh dengan kejadian pre eklampsia berat adalah asupan kalsium (koefisien = 0,477). Kesimpulan Ada  hubungan paritas, riwayat kehamilan dan asupan kalsium dengan kejadian pre eklampsia berat di UPT Puskesmas Jepang..Kata Kunci      : Preeklampsia berat, paritas, riwayat kehamilan, asupan kalsiu ABSTRACT Background: Preeclampsia / eclampsia is one of the major causes of perinatal morbidity and mortality in Indonesia. Until now the disease of preeclampsia / eclampsia is still a matter of obstetrics that can not be eradicated completely. Preeclampsia is a disease whose number of events in each country is different. Objective: To determine the relationship of parity, pregnancy history, and calcium intake with the incidence of severe pre eclampsia Method: In this study the population is all pregnant women who do the ANC at the Health Center of Jepang District Mejobo Kudus Regency in August 2017 as many as 30 pregnant women. Samples in this study were pregnant women who visited the ANC at the Puskesmas Jepang District Mejobo Kudus District on in August 2017 as many as 30 people. Data analysis used univariate and bivariate analysis. Result of research Majority of respondents have multiparity parity as many as 18 people (60%), and primipara 12 (40%). The majority of respondents have a history of never preeclampsia  as many as 16 people (53.3%) and who ever peb as many as 14 people (46.7%). The majority of respondents have enough intake of calcium as many as 18 people (60%) and who intake of calcium is not enough as many as 12 people (40%). The majority of respondents are not preeclampsia as many as 18 people (60%) and who preeclampsia  as many as 12 people (40%). There is a parity relationship with the incidence of severe eclampsia in Puskesmas Jepang upt (p value = 0.001). There was a correlation of pregnancy history with severe pre eclampsia incidence at upt Puskesmas jepang  (p value = 0,001). There is a correlation of calcium intake with severe pre eclampsia occurrence at UPT Puskesmas jepang  (p value = 0,009). Based on regression analysis the most influential factor with severe pre eclampsia incidence was calcium intake (coefficient = 0.477). Conclusion There was a parity relationship, a history of pregnancy and calcium intake with severe preeclampsia events at the UPT Puskesmas Jepang. . Keywords: severe preeclampsia, parity, pregnancy history, calcium supplements  


2020 ◽  
Vol 7 (1) ◽  
pp. 32-38
Author(s):  
Alfi Noviyana ◽  
Purwati Purwati

The conditions of pregnancy can increase anxiety in women, therefore it can cause a negativeimpact on pregnant women themselves and on their fetuses. Anxiety is one of the risk factors ofthe incidence of pre-eclampsia in pregnant women. Pre-eclampsia is still the top three causes ofmaternal death in the field of obstetrics in Indonesia. The purpose of this study is to know andanalyze the relationship of anxiety with the incidence of pre-eclampsia in RSUD Dr. R. GoetengTarunadibrata Purbalingga. This research is a quantitative study, with case control design,sampling technique with an accidental sampling approach. Data collection using a standardquestionnaire from Hamilton. Analysis in quantitative studies using the X2 test (chi square) Theresults of this study that there is no statistical relationship between anxiety and the incidence ofpre-eclampsia with a value of ρ = 0.732 but clinically found that mothers with anxiety have a riskof 1, 26 times higher experience pre-eclampsia ( value of OR = 1.26). As for some externalvariables in this study that theoretically become a predisposing factor for pre-eclampsia includingage, previous history of pre-eclampsia or hypertension, hereditary history, history of hormonalfamily planning acceptors related to pre-eclampsia.


2020 ◽  
Vol 5 (2) ◽  
pp. 144-149
Author(s):  
Budi Asty Andini ◽  
Khobibah Khobibah ◽  
Mimi Ruspita

Background: Sexual intercourse during pregnancy is a physiological need for pregnant women that is influenced by factors of perception from within oneself and previous experience and gender role factors in the family with the aim of knowing the relationship between gender roles and sexual relations in pregnant women. Methods: Non-experimental research with a population of all pregnant women in the village of Curugsewu in the District of Patean. The total sample of pregnant women receiving antenatal care was 30 with the Kendal statistical test. Results: significance T = 0.022 <0.005 there is a relationship between gender roles and sexual relations of sufficient strength in the negative direction -391*.Conclusion: there is a relationship between gender roles and sexual relations, the husband's role is very dominant but the frequency of sex in early pregnancy is largely not done because it is influenced by cultural factors and a history of previous abortion sex.


2017 ◽  
Vol 2 (1) ◽  
pp. 40
Author(s):  
Safrillah - Safrillah

Balia is a traditional ritual which is potentially disappeared due to the development of modern health care and the influence of Islam. In fact, balia still exists in this ever changing world. Balia even attracts public attention when it was performed in the main stage of Festival Nomoni in 2016. Balia has become ‘the bridge’ between the history of Kaili and Bugis through Sawerigading. Balia is a symbolic expression of the relationship between human beings and their spiritual nature that was originated from belief system towards god (dewa) and spirit (roh) which control the object of nature. Balia can survive because of its efficacy to cure diseases even though it is economically quite expensive. The efficacy of balia seems to confirm the view that disease is a 'spiritual game', which is identified with idolatry (kemusyrikan). In the face of conflict with the teachings of Islam, Kaili residents use the strategy of 'cultural dialogue' by integrating elements and symbols of Islam in the implementation of the tradition of balia.


2020 ◽  
Vol 3 (2) ◽  
pp. 86-96
Author(s):  
Chalank Kanbe ◽  
Ali Galleb ◽  
Hanaa Al –Ani

Obesity is one of the most common nutritional problems of complicating pregnancy.Compared with normal-weight women, obese women have a greater risk of developing.complications during pregnancy Objective: The aim of this study is to compare maternal outcome of pregnancy in relation to .body mass index .Study design: Prospective study.Setting: Kirkuk General Hospital, from 1st of January 2017 to the end of June 2017 Patients and methods: A total number of 150 pregnant women are included in this study. The studied women are divided into three groups according to their BMI of; first group with BMI from (18.5kg/m2-24.9kg/m2), the second group (25 kg/m2 to 29.9kg/m2), and the third group from 30kg/m2 and above. Each group consists of 50 pregnant women. Singleton pregnancy, both primigravida and multigravida of completed 37 weeks-42 weeks are included in this study. Women with previous caesarean section, women with history of severe hyperemesis gravidarum, pregnant women with heart diseases and thyroid disorders, generalized oedema,.blood diseases and autoimmune diseases are excluded from this study Results: In this study highly significant relation is found between hypertension and increase BMI (p=0.000). Equal number of diabetes mellitus is found in all groups 2% (p=1.000). It is noticed that history of infertility and intrauterine death rose with increasing BMI. The results shows that most of women with normal BMI delivered vaginally compared with overweight and obese women. While delivery by Cesarean section is more frequent in both over weight.)and obese pregnant women, the relation is highly significant (p= 0.000:Conclusions: Regarding the results of this study, the following can be concluded.High BMI significantly increases the risk of delivery by cesarean section Obesity is associated with increased incidence of hypertension, infertility, and IUD.


Author(s):  
A. Dzyubaylo ◽  
V. Lotkov

The article presents the results of the relationship of Smoking in women with a history of obstetric (OAA). The study is based on the results of a survey of 107 smokers and 136 non-Smoking women observed in the antenatal clinic for pregnancy. The study found an increase in the number of miscarriages and abortions in Smoking women compared to non-smokers. Detection of Smoking women of fertile age when attached to outpatient clinics, active detection of Smoking pregnant women, as well as Smoking relatives in the family, carrying out measures to reduce Smoking significantly reduce the likelihood of having children with chronic pathology.


Author(s):  
Kattan Gribetz Sarit

The rabbinic corpus begins with a question — “when?” — and is brimming with discussions about time and the relationship between people, God, and the hour. This book explores the rhythms of time that animated the rabbinic world of late antiquity, revealing how rabbis conceptualized time as a way of constructing difference between themselves and imperial Rome, Jews and Christians, men and women, and human and divine. Each chapter explores a unique aspect of rabbinic discourse on time. The book shows how the ancient rabbinic texts artfully subvert Roman imperialism by offering “rabbinic time” as an alternative to “Roman time.” It examines rabbinic discourse about the Sabbath, demonstrating how the weekly day of rest marked “Jewish time” from “Christian time.” The book looks at gendered daily rituals, showing how rabbis created “men's time” and “women's time” by mandating certain rituals for men and others for women. The book delves into rabbinic writings that reflect on how God spends time and how God's use of time relates to human beings, merging “divine time” with “human time.” Finally, it traces the legacies of rabbinic constructions of time in the medieval and modern periods. In doing so, the book sheds new light on the central role that time played in the construction of Jewish identity, subjectivity, and theology during this transformative period in the history of Judaism.


2021 ◽  
Vol 18 (2(Suppl.)) ◽  
pp. 1086
Author(s):  
Haider Turky Mousa Al-Mousawi ◽  
Qabas Neamah AL-Hajjar

Human cytomegalovirus (CMV) is the globally highly prevalent herpesvirus worldwide. CMV infects populations of all ages according to the Center for Disease Control and Prevention (CDC) and World Health Organization (WHO). CMV infections remain the most common viral complication potentially multiple in humans and are a major cause of congenital normality in women, which is why they are critical for diagnosis in several times when it happens during pregnancy. Pregnant women with CMV infection can be in charge of abortion or congenital expandaedby. This study involves the collection a total of (90) samples taken from each aborted and pregnant woman (70 with abortion cases and 20 of pregnant without history of abortion as control subjects) referring to Babylon teaching hospital for Maternity and Children, covering a period from (October 2018 to March 2019) to investigate the occurrence of Cytomegalovirus (CMV) in Babylon city. Patients and controls were evaluated for IgG, IgM antibodies and anti-HCMV IgG, IgM for (90) subjects were controlled in this study using the Enzyme Immunoassay Test Kit and read by enzyme - linked immunosorbent analyze (ELISA). In addition the  polymerase  chain reaction (PCR)  DNA  detection  for  CMV  are  based  on  the  amplification  of  pathogen  genomes  in  a particular  region  using different primers. The Chi-square test was used to analyze the data. The results show among 90 samples, women were evaluated for CMV infection, the seroprevalence titer was significantly higher at P <0.05 in seropositive cases ranging from 62(89%) toward positive CMV IgG, while the 65 (93%) of patients were positive CMV IgM from (70) women with abortions. By contrast, the results obtained from the controls were 9 (45%) subjects seropositive for IgG and all of them were seronegative with IgM. The anti – HCMV IgG finding showed high positivity that represents the furthermost of CMV infections among females through ages ranging between 20-29 years. Furthermore, the outcomes of molecular detection showed that a small number of samples 13 (19%) were HCMV DNA detectable in aborted women less than in pregnant women 3 (15%).       


e-CliniC ◽  
2019 ◽  
Vol 8 (1) ◽  
Author(s):  
Widia R. Husain ◽  
Freddy Wagey ◽  
Eddy Suparman

Abstract: To date, the main cause of maternal mortality rate is bleeding. Placenta previa is one of the causes of bleeding in pregnant women. This study was aimed to obtain the relationship between the occurence of placenta previa and pregnancy history among patients at RS Bhayangkara Manado, RSU GMIM Pancaran Kasih Manado, Prof. Dr. R. D. Kandou Hospital Manado. This was a descriptive and retrospective study with a cross sectional design. Subjects were pregnant women or women who laboured from January 2017 to December 2018 that had placenta previa. There were 72 cases as subjects, obtained by using non random sampling. The results showed that placenta previa were most common among subjects aged ≥35 tahun as many as 30 subjects (41.7%), multiparity as many as 39 subjects (54.2%), no history of sectio caesarea as many 39 subjects (54.2%), and no history of curetage as many as 66 subjects (91.7%). In conclusion, there were relationships between the occurence of placenta previa and age ≥35 years as well as multiparity, albeit, there were no relationships between the occurence of placenta previa and sectio caesaria as well as curetage history.Keywords: placenta previa, age, parity, histories of sectio caesarea and curetage Abstrak: Penyebab angka kematian ibu (AKI) yang utama ialah perdarahan. Plasenta previa merupakan salah satu penyebab perdarahan yang tersering terjadi pada ibu hamil. Penelitian ini bertujuan untuk mengetahui hubungan kejadian plasenta previa dengan riwayat kehamilan sebelumnya di RS Bhayangkara Manado, RSU GMIM Pancaran Kasih Manado dan RSUP Prof. Dr. R. D. Kandou Manado. Jenis penelitian ialah deskriptif retrospektif dengan desain potong lintang. Subyek penelitian ialah ibu hamil atau bersalin yang mengalami plasenta previa pada periode Januari 2017-Desember 2018 yang berjumlah 72 kasus, diperoleh dengan metode non random sampling. Hasil penelitian menunjukkan kejadian plasenta previa terbanyak pada usia ibu >35 tahun yaitu 30 orang (41,7%), paritas multipara yaitu 39 orang (54,2%), tidak ada riwayat seksio sesarea yaitu 39 orang (54,2%), dan tidak ada riwayat kuretase yaitu 66 orang (91,7%). Simpulan penelitian ini ialah terdapat hubungan kejadian plasenta previa dengan usia ibu dan multiparitas namun tidak terdapat hubungan dengan riwayat seksio sesarea dan riwayat kuretase.Kata kunci: plasenta previa, umur ibu, paritas, riwayat seksio sesaria dan riwayat kuretase


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