scholarly journals Dittrichia Viscosa L. Greuter: Phytochemistry and Biological Activity

2008 ◽  
Vol 3 (11) ◽  
pp. 1934578X0800301
Author(s):  
Alejandro F. Barrero ◽  
M. Mar Herrador ◽  
Pilar Arteaga ◽  
Julieta V. Catalán
Keyword(s):  
Biological Activity ◽  
Mediterranean Region ◽  
Biological Activities ◽  
Dittrichia Viscosa ◽  
The Mediterranean ◽  
Anti Inflammatory

Dittrichia viscosa is a plant widely distributed in the Mediterranean region. This species and its components present a broad range of biological activities (for example, anti-inflammatory, antifungal, antiulcer, antiviral, antiparasitic), which are reviewed. Extracts of the species are particularly rich in terpenoids, in particular eudesmane acids, notably ilicic acid (45) and α-costic acid (44). Flavonoids are also abundant, especially during flowering.

AN UPDATE ON THE SYNTHESIS OF BENZOXAZOLES

2017 ◽  
Vol 10 (10) ◽  
pp. 48 ◽  
Author(s):  
Jyothi M ◽  
Ramchander Merugu
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Biological Activity ◽  
Biological Activities ◽  
Starting Material ◽  
Bioactive Molecules ◽  
Living Systems ◽  
Inflammatory Activity ◽  
Anti Inflammatory

Benzoxazoles being structurally similar to bases adenine and guanine interact with biomolecules present in living systems. These compounds possess antimicrobial, central nervous system activities, antihyperglycemic potentiating activity, analgesic, and anti-inflammatory activity. It can also be used as starting material for other bioactive molecules. Modifications in structure and the biological profiles of new generations of benzoxazoles were found to be more potent with enhanced biological activity. Considering all these, we have prepared this review and discussed the synthesis and biological activities of benzoxazoles.

scholarly journals Isolation and Quantification of Pinitol, a Bioactive Cyclitol, in Retama spp

2016 ◽  
Vol 11 (3) ◽  
pp. 1934578X1601100 ◽  
Author(s):  
Nuria H. González-Mauraza ◽  
Antonio J. León-González ◽  
José L. Espartero ◽  
Juan B. Gallego-Fernández ◽  
Marina Sánchez-Hidalgo ◽  
...  
Keyword(s):  
Mediterranean Region ◽  
2D Nmr ◽  
Spectroscopic Techniques ◽  
Aqueous Extracts ◽  
Aerial Parts ◽  
The Mediterranean ◽  
Anti Inflammatory ◽  
Identification And Quantification

The genus Retama (Fabaceae) is widely distributed in the Mediterranean region. In the present study, pinitol (3- O-methyl- chiro-inositol), an anti-inflammatory and antidiabetic molecule, was isolated from aerial parts of R. monosperma, and its structure established on the basis of spectroscopic techniques (1D/2D NMR) and MS. Identification and quantification of pinitol in R. raetam and R. sphaerocarpa were also performed. R. monosperma had the highest concentration of pinitol (2.3%). The presence of pinitol in aqueous extracts of Retama spp. may explain the adaptation of these plants to drought and salinity. Furthermore, pinitol could be considered as a mediator in the anti-inflammatory and hypoglycemic activities of Retama spp., which are traditionally used to treat diabetes.

A Review: Therapeutic and Biological Activity of Benzothiazole Derivatives

2017 ◽  
Vol 4 (3) ◽  
Author(s):  
Suresh Choudhary ◽  
G Jeyabalan ◽  
Naresh Kalra
Keyword(s):  
Biological Activity ◽  
Biological Activities ◽  
New Products ◽  
Therapeutic Agents ◽  
Present Review ◽  
Benzothiazole Derivatives ◽  
Anti Inflammatory

The Benzothiazole nucleus is present in compounds involved in research aimed at evaluating new products that possess interesting biological activities, such as antitumor, antimicrobial, anthelmintic, antileishmanial, anticonvulsant and anti-inflammatory. The present review focuses on the benzothiazoles with potential activities that are now in development. The synthesized benzothiazole derivatives could be considered as lead molecule for the development of therapeutic agents.

Overview of Coumarins and its Derivatives: Synthesis and Biological Activity

2020 ◽  
Vol 17 ◽  
Author(s):  
Tanvi Sahni ◽  
Sunita Sharma ◽  
Diksha Verma ◽  
Pardeep Kaur
Keyword(s):  
Biological Activity ◽  
Pharmaceutical Industry ◽  
Schiff Bases ◽  
Enzyme Inhibitors ◽  
Biological Activities ◽  
Anti Inflammatory

Abstract: Coumarin is a heterocyclic scaffold and its derivatives namely Schiff bases, esters, and hydrazides, etc, play an important role in the field of agrochemical and pharmaceutical industry due to its structure. Over the years, various biological activities like antifungal, antimicrobial, anti-viral, anti-cancerous, anti-tumor, anti-inflammatory, anti-filarial, enzyme inhibitors, anti-aflatoxigenic, analgesics, antioxidant and Oestrogenic, etc had been analyzed. This review covers the latest literature and knowledge on the synthetic procedures for various coumarin and its derivatives, biological and pharmacological applications.

An Overview: 1, 3, 4- oxadiazole and its uses

2021 ◽  
pp. 389-392
Author(s):  
Anuja S. Patil. ◽  
Shrinivas K. Mohite
Keyword(s):  
Biological Activity ◽  
Heterocyclic Compound ◽  
Heterocyclic Compounds ◽  
Functional Group ◽  
Biological Activities ◽  
Anti Inflammatory ◽  
Anti Hiv

Heterocyclic compounds show various potent biological activity. Every heterocyclic compound has different structure, different functional group and designed for different biological activities. Oxadiazole is one of those heterocyclic compounds possess various biological activity. The structure is simple contain carbon, nitrogen, oxygen, hydrogen. It shows various type of biological activities such as anti- convulsant, anti- microbial, anti- tumor, anti-helminth, anti- HIV, anti- Alzheimer, insecticidal, pesticidal, anti- inflammatory. This review gives a glance on oxadiazole compound, its different derivatives and its biological uses.

scholarly journals Biological activity and flavonoid profile of five species of the Bursera genus

2020 ◽  
Vol 98 (4) ◽  
pp. 545-553
Author(s):  
Ma. Beatriz Sánchez ◽  
Ana María García ◽  
José Luis Contreras ◽  
David Eduardo Torres ◽  
Rubén San Miguel ◽  
...  
Keyword(s):  
Biological Activity ◽  
Biological Activities ◽  
Research Question ◽  
Antifungal Effect ◽  
Antibacterial And Antifungal Activities ◽  
Medicinal Use ◽  
Flavonoid Composition ◽  
Anti Inflammatory ◽  
Antibacterial And Antifungal ◽  
Edema Inhibition

Background: The genus Bursera Jacq. ex. L. concentrates its diversity in Mexico. Among the secondary metabolites that can be isolated from organic its extracts are flavonoids and lignans. Research question: Do the biological activity of the hydroalcoholic extracts from five Bursera species studied depend on their flavonoid content? Study site: Oaxaca, Mexico. Methods: The extracts of B. aptera Ramírez, B. fagaroides (Kunth) Engl., B. schlechtendalii Engl., B. galeottiana Engl., B. morelensis Ramírez were analyzed by High Resolution Liquid Chromatography (HPLC) to determine their flavonoid composition. The antiradical DPPH, anti-inflammatory, antibacterial and antifungal activities of the extracts were determined. Results: Phlorizin and quercetin were conserved in both stems and leaves of the five species studied. The phloretin was present only in the leaves of B. aptera. The highest antibacterial activity was observed against Staphylococcus epidermidis and Salmonella typhimurium by the extracts of leaves of B. aptera (MIC 0.002 mg/mL) and the stems of B. fagaroides (MIC 0.015 mg/mL). The extract of stems of B. morelensis against Fusarium boothii presented the highest antifungal effect (lower than 50 ?g/mL). The anti-inflammatory activity of B. fagaroides was 51.24 % edema inhibition (1 mg/ear) compare to 78.76 % of indomethacin (0.358 mg/ear). Conclusion: The presence of flavonoids in five species studied suggests the richness of these compounds in Bursera genus. The biological activities studied indicated the potential medicinal use of these species and the role that the flavonoids play in plant physiology.

scholarly journals 3,4-dihydro-2H-1,3-benzoxazines and their oxo-derivatives chemistry and bioactivities

2020 ◽  
pp. 1-1 ◽  
Author(s):  
El-Din Sharaf
Keyword(s):  
Biological Activity ◽  
Bioactive Compounds ◽  
Biological Activities ◽  
Anti Inflammatory ◽  
Derivatives Of ◽  
Anti Hiv ◽  
Significant Class

3,4-Dihydro-2H-1,3-benzoxazines derivatives are a significant class of heterocycles with a particular awareness due to their remarkable biological activities in humans, plant as well as in animals and also, they are naturally occurrence. Because of alteration in the benzoxazines skeleton, beside their comparative chemical simplicity and accessibility, make these compounds to be suitable sources of other bioactive compounds. Resulting in the discovery of a wide set of these compounds that have a broad biological activity such as antifungal, antibacterial, anti-HIV, anticancer, anticonvulsant, anti-inflammatory and so on. Subsequently, this review herein gives a brief overview of derivatives of 3,4-dihydro-2H-1,3-benzoxazines monomers and their oxo-derivatives chemistry and bioactivities.

scholarly journals A Review on Synthesis and Biological Activity of Thiazole and its Derivatives

2021 ◽  
Vol 70 (1) ◽  
Author(s):  
Namitha TH ◽  
Saranya S Nair ◽  
Dr.Arun Kumar ◽  
Dr.Vinod B ◽  
Dr.Daisy P A
Keyword(s):  
Biological Activity ◽  
Pharmacological Activity ◽  
Biological Activities ◽  
Synthetic Compounds ◽  
The Past ◽  
Current Review ◽  
Heteroaromatic Ring ◽  
Wide Range ◽  
Anti Inflammatory

Thiazole, a five-membered heteroaromatic ring, is an important framework of a large number of synthetic compounds. Its diverse pharmacological activity is mirrored in many clinically approved thiazole-containing molecules with, wide range of biological activities, such as antibacterial, antifungal, antiviral, anthelmintic, antitumor, and anti-inflammatory effects. The current review provides an overview of the biological activities of thiazole during the past years.

Bioactive Flavonoids from Verbenaceae

2020 ◽  
Vol 17 (6) ◽  
pp. 754-766
Author(s):  
Kui-Wu Wang ◽  
Ting-Ting Zhang
Keyword(s):  
Biological Activity ◽  
Biological Activities ◽  
Structural Diversity ◽  
Plant Kingdom ◽  
Anti Oxidant ◽  
Anti Inflammatory

Flavonoids are widely distributed in the plant kingdom and possess a variety of biological activities, such as anti-oxidant, anti-inflammatory, and anti-viral activities. Due to the structural diversity and biological activity, flavonoid derivatives isolated from Verbenaceae family have received a lot of attention by the research scholars. In this paper, a total of 150 natural flavonoids isolated from Verbenaceae and their bioactivities were summarized.

scholarly journals A Comprehensive Review of Phytochemistry and Biological Activities of Quercus Species

Forests ◽  
2020 ◽  
Vol 11 (9) ◽  
pp. 904
Author(s):  
Ema Burlacu ◽  
Adrian Nisca ◽  
Corneliu Tanase
Keyword(s):  
Biological Activity ◽  
Biological Activities ◽  
Acne Vulgaris ◽  
Anticancer Activities ◽  
Exclusion Criteria ◽  
Research Fields ◽  
Lack Of Information ◽  
Quercus Species ◽  
Volatile Organic ◽  
Anti Inflammatory

The Quercus genus provides a large amount of biomaterial with many applications in fields like pharmaceutics, cosmetics, and foodstuff areas. Due to the worldwide dissemination of the genus, many species were used for centuries in traditional healing methods or in the wine maturing process. This review aims to bring together the results about phytoconstituents from oak extracts and their biological applicability as antioxidants, antimicrobial, anticancer, etc. The literature data used in this paper were collected via PubMed, Scopus, and Science Direct (2010–June 2020). The inclusion criteria were papers published in English, with information about phytoconstituents from Quercus species (leaves, bark and seeds/acorns) and biological activities such as antioxidant, antibacterial, antiobesity, anti-acne vulgaris, antifungal, anticancer, antiviral, antileishmanial, antidiabetic, anti-inflammatory. The exclusion criteria were the research of other parts of the Quercus species (e.g., galls, wood, and twigs); lack of information about phytochemistry and biological activities; non-existent Quercus species reported by the authors. The most studied Quercus species, in terms of identified biomolecules and biological activity, are Q. brantii, Q. infectoria and Q. robur. The Quercus species have been reported to contain several phytoconstituents. The main bioactive phytochemicals are phenolic compounds, volatile organic compounds, sterols, aliphatic alcohols and fatty acids. The, Quercus species are intensely studied due to their antioxidant, anti-inflammatory, antimicrobial, and anticancer activities, provided by their phytochemical composition. The general conclusion is that oak extracts can be exploited for their biological activity and can be used in research fields, such as pharmaceutical, nutraceutical and medical.

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